NO20020330L - Nye vitamin D-derivater med sykliske strukturer i deres sidekjeder, metode og mellomprodukter for deres fremstilling ogbruk ved fremstilling av medikamenter - Google Patents

Nye vitamin D-derivater med sykliske strukturer i deres sidekjeder, metode og mellomprodukter for deres fremstilling ogbruk ved fremstilling av medikamenter

Info

Publication number: NO20020330L
Authority: NO; Norway
Prior art keywords: alkyl; formula; give; new; perhydroindane
Prior art date: 1999-07-23

Application number

NO20020330A

Other languages

English (en)

Norwegian (no)

Other versions

NO20020330D0 (no

Inventor

Andreas Steinmeyer

Katica Schwarz

Claudia Giesen

Martin Haberey

Marianne Faehnrich

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-23

Filing date

2002-01-22

Publication date

2002-03-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7916563&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20020330(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-01-22 Application filed by Schering Ag filed Critical Schering Ag

2002-01-22 Publication of NO20020330D0 publication Critical patent/NO20020330D0/no

2002-03-22 Publication of NO20020330L publication Critical patent/NO20020330L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- B—PERFORMING OPERATIONS; TRANSPORTING
- B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
- B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES, PROFILES OR LIKE SEMI-MANUFACTURED PRODUCTS OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
- B21C25/00—Profiling tools for metal extruding
- B21C25/02—Dies
- B—PERFORMING OPERATIONS; TRANSPORTING
- B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
- B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES, PROFILES OR LIKE SEMI-MANUFACTURED PRODUCTS OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
- B21C25/00—Profiling tools for metal extruding
- B21C25/10—Making tools by operations not covered by a single other subclass
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Mechanical Engineering (AREA)
Pulmonology (AREA)
Obesity (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Immunology (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Thiazole And Isothizaole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20020330A 1999-07-23 2002-01-22 Nye vitamin D-derivater med sykliske strukturer i deres sidekjeder, metode og mellomprodukter for deres fremstilling ogbruk ved fremstilling av medikamenter NO20020330L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19935771A DE19935771A1 (de)	1999-07-23	1999-07-23	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
PCT/EP2000/007104 WO2001007405A2 (de)	1999-07-23	2000-07-24	Neue vitamin d-derivate mit cyclischen substrukturen in den seitenketten, verfahren und zwischenprodukte zu ihrer herstellung und die verwendung zur herstellung von arzneimitteln

Publications (2)

Publication Number	Publication Date
NO20020330D0 NO20020330D0 (no)	2002-01-22
NO20020330L true NO20020330L (no)	2002-03-22

Family

ID=7916563

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20020330A NO20020330L (no)	1999-07-23	2002-01-22	Nye vitamin D-derivater med sykliske strukturer i deres sidekjeder, metode og mellomprodukter for deres fremstilling ogbruk ved fremstilling av medikamenter

Country Status (29)

Country	Link
US (2)	US6603031B1 (ru)
EP (2)	EP1210327B1 (ru)
JP (1)	JP2003505447A (ru)
KR (1)	KR100713744B1 (ru)
CN (1)	CN1372543A (ru)
AT (1)	ATE316073T1 (ru)
AU (1)	AU773673B2 (ru)
BG (1)	BG106334A (ru)
BR (1)	BR0013175A (ru)
CA (1)	CA2376465A1 (ru)
CZ (1)	CZ2002150A3 (ru)
DE (2)	DE19935771A1 (ru)
DK (1)	DK1210327T3 (ru)
EA (1)	EA004703B1 (ru)
EE (2)	EE200800025A (ru)
ES (1)	ES2254222T3 (ru)
HR (1)	HRP20020161A2 (ru)
HU (1)	HUP0202015A3 (ru)
IL (2)	IL147634A0 (ru)
MX (1)	MXPA01013330A (ru)
NO (1)	NO20020330L (ru)
NZ (1)	NZ515891A (ru)
PL (1)	PL353102A1 (ru)
SI (1)	SI1210327T1 (ru)
SK (1)	SK872002A3 (ru)
UA (1)	UA82307C2 (ru)
WO (1)	WO2001007405A2 (ru)
YU (1)	YU4402A (ru)
ZA (1)	ZA200201482B (ru)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6242434B1 (en)	1997-08-08	2001-06-05	Bone Care International, Inc.	24-hydroxyvitamin D, analogs and uses thereof
US6566353B2 (en) *	1996-12-30	2003-05-20	Bone Care International, Inc.	Method of treating malignancy associated hypercalcemia using active vitamin D analogues
US20020128240A1 (en) *	1996-12-30	2002-09-12	Bone Care International, Inc.	Treatment of hyperproliferative diseases using active vitamin D analogues
DE19935771A1 (de) *	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
AU7895601A (en) *	2000-07-18	2002-01-30	Bone Care Int Inc	Stabilized 1alpha-hydroxy vitamin d
EP1559708A4 (en) *	2002-10-10	2006-07-19	Wisconsin Alumni Res Found	2,2-DISUBSTITUTED 1A, 25-DIHYDROXY-19-NORVITAMINE D DERIVATIVE
EP1458678A1 (en) *	2002-11-18	2004-09-22	Teva Pharmaceutical Industries Limited	A crystallization method for purification of calcipotriene
NZ545804A (en) *	2003-09-19	2009-09-25	Wisconsin Alumni Res Found	Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-or-vitamin D derivatives and a bisphosphonate
WO2005027930A1 (en) *	2003-09-19	2005-03-31	Pfizer Products Inc.	2-alkylene-19-nor-vitamin d derivatives for the treatment of osteosarcoma
WO2005027922A1 (en) *	2003-09-19	2005-03-31	Pfizer Products Inc.	2-alkylidene-19-nor-vitamin d derivatives for the treatment of hypogonadism or andropause
WO2005027918A1 (en) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a cyclooxgenase-2 inhibitor
WO2005027916A1 (en) *	2003-09-19	2005-03-31	Pfizer Products Inc.	Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and aromatase inhibitors
AU2004273667A1 (en) *	2003-09-19	2005-03-31	Wisconsin Alumni Research Foundation (Warf)	2-alkylidene-19-nor-vitamin D derivatives for the treatment of osteopenia or male osteoporosis
JP4795023B2 (ja) *	2004-02-03	2011-10-19	中外製薬株式会社	ビタミンｄ化合物及びそれらの合成中間体の合成方法
US7094775B2 (en)	2004-06-30	2006-08-22	Bone Care International, Llc	Method of treating breast cancer using a combination of vitamin D analogues and other agents
DE102005017775A1 (de) *	2005-04-13	2006-10-19	Schering Ag	Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins
GB0608806D0 (en) *	2006-05-04	2006-06-14	Lipopeptide Ab	Combination therapy product and uses thereof
JP2010502624A (ja) *	2006-08-29	2010-01-28	テバファーマシューティカルインダストリーズリミティド	低ｐＨ親和性を有するコルチコステロイド化合物及びビタミンＤ含有化合物を含む安定な薬理活性組成物
WO2012151058A1 (en)	2011-05-03	2012-11-08	Wisconsin Alumni Research Foundation	(20s)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin d3 analogs and their uses
US10548908B2 (en)	2016-09-15	2020-02-04	Nostopharma, LLC	Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3933034A1 (de)	1989-10-02	1991-04-11	Schering Ag	24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
DE4003854A1 (de) *	1990-02-06	1991-08-08	Schering Ag	Seitenketten-homologe vitamin d-derivate, verfahren zu ihrer herstellung, diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
US5532228A (en) *	1990-02-06	1996-07-02	Schering Aktiengesellschaft	Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
ES2055521T3 (es) *	1990-02-06	1994-08-16	Schering Ag	Derivados de vitamina d que son homologos en la cadena lateral, procedimiento para su preparacion, preparados farmaceuticos que contienen estos derivados asi como su utilizacion como medicamentos.
PL171580B1 (pl) *	1991-11-07	1997-05-30	Res Inst Medicine Chem	Sposób wytwarzania nowych analogów witaminy D3 PL PL PL
DE4220757A1 (de) *	1992-06-24	1994-01-05	Schering Ag	Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
GB9309422D0 (en) *	1993-05-07	1993-06-23	Res Inst Medicine Chem	Chemical compounds
ATE191712T1 (de) *	1993-07-09	2000-04-15	Theramex	Neue strukturelle vitamin d derivate
GB9315253D0 (en) *	1993-07-23	1993-09-08	Res Inst Medicine Chem	Chemical compounds
US5384313A (en) *	1993-11-24	1995-01-24	Wisconsin Alumni Research Foundation	21-norvitamin D compounds
GB9325415D0 (en) *	1993-12-13	1994-02-16	Res Inst Medicine Chem	Chemical compounds
US5384314B1 (en) *	1994-03-11	1997-08-05	Hoffmann La Roche	1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
GB9405715D0 (en) *	1994-03-23	1994-05-11	Res Inst Medicine Chem	Chemical compounds
EP0712843B1 (en)	1994-06-07	1999-11-17	Teijin Limited	Vitamin d3 derivative and process for producing the same
ATE178596T1 (de)	1994-12-14	1999-04-15	Duphar Int Res	Vitamin-d-derivate und verfahren zur herstellung dieser verbindungen
DE19619036A1 (de) *	1996-04-30	1997-11-13	Schering Ag	Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
SG70010A1 (en)	1996-05-23	2000-01-25	Hoffmann La Roche	Fluorinated vitamin d3 analogs
US5945410A (en) *	1997-03-17	1999-08-31	Wisconsin Alumni Research Foundation	2-alkyl-19-nor-vitamin D compounds
MA26481A1 (fr) *	1997-04-21	2004-12-20	Hoffmann La Roche	Derives d'arylsecocholadiene
JP2002508383A (ja)	1997-12-17	2002-03-19	シエーリングアクチエンゲゼルシャフト	側鎖中にリン原子を有するビタミンｄ誘導体
EP0927721A1 (de) *	1997-12-17	1999-07-07	Schering Aktiengesellschaft	Neue Vitamin D-Derivate mit Phosphoratomen in den Seitenketten, Zwischenprodukte bei ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
EP0957098A1 (en) *	1998-05-14	1999-11-17	F. Hoffmann-La Roche Ag	Intermediates for the synthesis of 3-epi vitamin D3 metabolites and analogs
US6177688B1 (en) *	1998-11-24	2001-01-23	North Carolina State University	Pendeoepitaxial gallium nitride semiconductor layers on silcon carbide substrates
DE19935771A1 (de) *	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
DE20118652U1 (de) *	2000-12-19	2002-03-21	Dräger Safety AG & Co. KGaA, 23560 Lübeck	Vorrichtung zur Befestigung von Augengläsern

1999
- 1999-07-23 DE DE19935771A patent/DE19935771A1/de not_active Withdrawn
2000
- 2000-07-24 CA CA002376465A patent/CA2376465A1/en not_active Abandoned
- 2000-07-24 DE DE50012087T patent/DE50012087D1/de not_active Expired - Fee Related
- 2000-07-24 HR HR20020161A patent/HRP20020161A2/hr not_active Application Discontinuation
- 2000-07-24 EE EEP200800025A patent/EE200800025A/xx unknown
- 2000-07-24 AU AU74072/00A patent/AU773673B2/en not_active Ceased
- 2000-07-24 PL PL00353102A patent/PL353102A1/xx not_active Application Discontinuation
- 2000-07-24 JP JP2001512492A patent/JP2003505447A/ja not_active Withdrawn
- 2000-07-24 EP EP00962278A patent/EP1210327B1/de not_active Expired - Lifetime
- 2000-07-24 HU HU0202015A patent/HUP0202015A3/hu unknown
- 2000-07-24 US US09/624,608 patent/US6603031B1/en not_active Expired - Fee Related
- 2000-07-24 YU YU4402A patent/YU4402A/sh unknown
- 2000-07-24 EA EA200200096A patent/EA004703B1/ru not_active IP Right Cessation
- 2000-07-24 EE EEP200200036A patent/EE05027B1/xx not_active IP Right Cessation
- 2000-07-24 AT AT00962278T patent/ATE316073T1/de not_active IP Right Cessation
- 2000-07-24 UA UA2002021477A patent/UA82307C2/ru unknown
- 2000-07-24 WO PCT/EP2000/007104 patent/WO2001007405A2/de not_active Ceased
- 2000-07-24 CN CN00810762A patent/CN1372543A/zh active Pending
- 2000-07-24 SI SI200030802T patent/SI1210327T1/sl unknown
- 2000-07-24 EP EP03090212A patent/EP1362848A1/de not_active Withdrawn
- 2000-07-24 MX MXPA01013330A patent/MXPA01013330A/es active IP Right Grant
- 2000-07-24 BR BR0013175-0A patent/BR0013175A/pt not_active Application Discontinuation
- 2000-07-24 NZ NZ515891A patent/NZ515891A/xx unknown
- 2000-07-24 KR KR1020027000905A patent/KR100713744B1/ko not_active Expired - Fee Related
- 2000-07-24 CZ CZ2002150A patent/CZ2002150A3/cs unknown
- 2000-07-24 ES ES00962278T patent/ES2254222T3/es not_active Expired - Lifetime
- 2000-07-24 SK SK87-2002A patent/SK872002A3/sk not_active Application Discontinuation
- 2000-07-24 IL IL14763400A patent/IL147634A0/xx active IP Right Grant
- 2000-07-24 DK DK00962278T patent/DK1210327T3/da active
2002
- 2002-01-15 IL IL147634A patent/IL147634A/en not_active IP Right Cessation
- 2002-01-21 BG BG106334A patent/BG106334A/bg unknown
- 2002-01-22 NO NO20020330A patent/NO20020330L/no not_active Application Discontinuation
- 2002-02-21 ZA ZA200201482A patent/ZA200201482B/en unknown
- 2002-11-26 US US10/303,916 patent/US7115758B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US7115758B2 (en)	2006-10-03
WO2001007405A2 (de)	2001-02-01
EA004703B1 (ru)	2004-06-24
AU7407200A (en)	2001-02-13
KR20020022780A (ko)	2002-03-27
DK1210327T3 (da)	2006-04-03
YU4402A (sh)	2005-03-15
EE05027B1 (et)	2008-06-16
MXPA01013330A (es)	2002-07-09
DE19935771A1 (de)	2001-02-01
US20030149006A1 (en)	2003-08-07
KR100713744B1 (ko)	2007-05-02
NO20020330D0 (no)	2002-01-22
CZ2002150A3 (cs)	2002-05-15
ES2254222T3 (es)	2006-06-16
SI1210327T1 (sl)	2006-04-30
IL147634A (en)	2006-10-31
ZA200201482B (en)	2003-07-30
EA200200096A1 (ru)	2002-06-27
EP1210327A2 (de)	2002-06-05
IL147634A0 (en)	2002-08-14
ATE316073T1 (de)	2006-02-15
UA82307C2 (ru)	2008-04-10
HRP20020161A2 (en)	2005-10-31
HUP0202015A3 (en)	2004-04-28
PL353102A1 (en)	2003-10-20
AU773673B2 (en)	2004-06-03
HUP0202015A2 (en)	2002-10-28
US6603031B1 (en)	2003-08-05
CN1372543A (zh)	2002-10-02
JP2003505447A (ja)	2003-02-12
EP1210327B1 (de)	2006-01-18
WO2001007405A3 (de)	2002-03-28
EE200200036A (et)	2003-04-15
SK872002A3 (en)	2002-09-10
NZ515891A (en)	2004-03-26
BR0013175A (pt)	2002-04-02
BG106334A (bg)	2002-06-28
EP1362848A1 (de)	2003-11-19
EE200800025A (et)	2008-06-16
DE50012087D1 (de)	2006-04-06
CA2376465A1 (en)	2001-02-01

Publication	Publication Date	Title
NO20020330D0 (no)	2002-01-22	Nye vitamin D derivater med sykliske strukturer i deres sidekjeder, metode og mellomprodukter for deres fremstilling ogbruk ved fremstilling av medikamenter
AR007253A1 (es)	1999-10-27	Derivados de pirimidina o sus sales y n-oxidos farmaceuticamente aceptables composicion farmaceutica que los contiene, procedimiento para preparar a dichosderivados y metodo para la preparacion de una composicion farmaceutica conteniendo a uno de dichos derivados
IL114996A (en)	1997-07-13	1-biphenylimidazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
WO2008033956A3 (en)	2008-11-27	Macrocyclic lactone compounds and methods for their use
ATE336484T1 (de)	2006-09-15	Pyrimidine verbindungen
HUT72662A (en)	1996-05-28	Serotonin receptor benzotiophene derivatives, pharmaceutical compositions containing them and process for their preparation
GB0204468D0 (en)	2002-04-10	Novel thioxanthone derivatives, and their use as cationic photoinitiators
DK1026167T3 (da)	2003-05-26	Tricykliske triazolobenzazepinderivater, fremgangsmåde til fremstilling af disse samt antiallergiske midler
NO306062B1 (no)	1999-09-13	Syremellomprodukter til bruk ved fremstilling av taxanderivater
ATE196904T1 (de)	2000-10-15	Benzodioxan derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
WO2003095427A1 (en)	2003-11-20	Spiro-ring compound
DK1092717T3 (da)	2003-04-14	Polycykliske azaindolforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske tilberedninger indeholdende disse
NO960441L (no)	1996-02-02	Benzopyraner og farmasöytiske forbindelser inneholdende dem
IL106993A (en)	1997-06-10	Benzenalkanoic acid derivatives and pharmaceutical compositions containing them
AR045209A1 (es)	2005-10-19	6-(1,1-difluoralquilo) -4- aminopicolinatos y su uso como herbicidas
DK1631557T3 (da)	2007-05-07	Cyklisk hydroxylamin som psykoaktive forbindelser
NO20002315D0 (no)	2000-05-02	Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem
ES8401056A1 (es)	1983-12-16	"procedimiento para la fabricacion de derivados de la quinolina".
ATE229513T1 (de)	2002-12-15	Disubstituierte trans-3,4,4a,5,6,10b-hexahydro-2h-napht(1,2-b)- ,4-oxazine, verfahren zu deren herstellung und diese enthaltende pharmazeutigsche zusammensetzungen
FR2737207B1 (fr)	1997-10-17	Nouvelles n-heterocyclyl-1-aryloxyalcoyl-4-piperidinamines substituees, leur preparation et leur application en therapeutique
NO955071D0 (no)	1995-12-14	abeo-Ergolin-derivater som 5HT1A-ligander
TNSN06337A1 (en)	2008-02-22	6-substituted pyridoindolone derivatives production and therapeutic use thereof
NO964672L (no)	1997-05-12	Nye tetracykliske 1,4-oksazinforbindelser, fremgangsmåter ved deres fremstilling og farmasöytiske sammensetninger innholdende dem
ATE383246T1 (de)	2008-01-15	Photosensible zusammensetzung und lithographischer druckplattenvorläufer, der diese zusammensetzung verwendet.
Yan et al.	2016	Facile Synthesis of (2-Amino-3-(benzothiazol-2-yl)-4H-chromen-4-yl) phosphonate Derivatives under Mild Conditions

Legal Events

Date	Code	Title	Description
2009-02-23	FC2A	Withdrawal, rejection or dismissal of laid open patent application