NO20020684D0 - Aminopyrazolderivater, fremgangsmåte for deres fremstilling og deres anvendelse som antitumormidler - Google Patents

Aminopyrazolderivater, fremgangsmåte for deres fremstilling og deres anvendelse som antitumormidler

Info

Publication number: NO20020684D0
Authority: NO; Norway
Prior art keywords: processes; preparation; antitumor agents; aminopyrazole derivatives; aminopyrazole
Prior art date: 1999-08-12

Application number

NO20020684A

Other languages

English (en)

Other versions

NO20020684L (no

Inventor

Paolo Pevarello

Paolo Orsini

Gabriella Traquandi

Mario Varasi

Edward L Fritzen

Martha A Warpehoski

Betsy S Pierce

Maria Gabriella Brasca

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-12

Filing date

2002-02-11

Publication date

2002-02-11

2002-02-11 Application filed by Upjohn Co filed Critical Upjohn Co

2002-02-11 Publication of NO20020684D0 publication Critical patent/NO20020684D0/no

2002-04-03 Publication of NO20020684L publication Critical patent/NO20020684L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Tropical Medicine & Parasitology (AREA)
Pulmonology (AREA)
Oncology (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Virology (AREA)
Vascular Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20020684A 1999-08-12 2002-02-11 3(5)-aminopyrazolderivater, fremgangsmåtet for deres fremstilling og deres anvendelse som antitumormidler NO20020684L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US37283199A	1999-08-12	1999-08-12
PCT/US2000/006699 WO2001012189A1 (en)	1999-08-12	2000-05-05	3(5)-amino-pyrazole derivatives, process for their preparation and their use as antitumor agents

Publications (2)

Publication Number	Publication Date
NO20020684D0 true NO20020684D0 (no)	2002-02-11
NO20020684L NO20020684L (no)	2002-04-03

Family

ID=23469802

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20020684A NO20020684L (no)	1999-08-12	2002-02-11	3(5)-aminopyrazolderivater, fremgangsmåtet for deres fremstilling og deres anvendelse som antitumormidler

Country Status (35)

Country	Link
US (2)	US7034049B1 (no)
EP (1)	EP1202733B1 (no)
JP (1)	JP2003507329A (no)
KR (1)	KR20020060160A (no)
CN (1)	CN1373662A (no)
AP (1)	AP2002002442A0 (no)
AR (1)	AR026122A1 (no)
AT (1)	ATE305782T1 (no)
AU (1)	AU4971400A (no)
BG (1)	BG106480A (no)
BR (1)	BR0013143A (no)
CA (1)	CA2383555C (no)
CZ (1)	CZ2002422A3 (no)
DE (1)	DE60023012T2 (no)
DK (1)	DK1202733T3 (no)
EA (1)	EA005373B1 (no)
EE (1)	EE200200065A (no)
ES (1)	ES2249270T3 (no)
GE (1)	GEP20053476B (no)
HK (1)	HK1046866A1 (no)
HR (1)	HRP20020128A2 (no)
HU (1)	HUP0203542A3 (no)
IL (1)	IL147923A0 (no)
IS (1)	IS6265A (no)
MA (1)	MA25493A1 (no)
MX (1)	MXPA02001498A (no)
NO (1)	NO20020684L (no)
NZ (1)	NZ517237A (no)
OA (1)	OA12046A (no)
PE (1)	PE20010130A1 (no)
PL (1)	PL353455A1 (no)
SK (1)	SK1812002A3 (no)
WO (1)	WO2001012189A1 (no)
YU (1)	YU9602A (no)
ZA (1)	ZA200201511B (no)

Families Citing this family (160)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9901691D0 (en)	1999-01-26	1999-03-17	Cerebrus Ltd	Chemical compounds
HUP0203542A3 (en) *	1999-08-12	2003-07-28	Upjohn Co	3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
WO2001057034A1 (en)	2000-02-07	2001-08-09	Bristol-Myers Squibb Co.	3-aminopyrazole inhibitors of cyclin dependent kinases
AU2001253540A1 (en)	2000-04-25	2001-11-07	Bristol-Myers Squibb Company	Use of 5-thio-, sulfinyl- and sulfonylpyrazolo(3,4-b)-pyridines as cyclin dependent kinase inhibitors
DE10037310A1 (de) *	2000-07-28	2002-02-07	Asta Medica Ag	Neue Indolderivate und deren Verwendung als Arzneimittel
US20020103185A1 (en) *	2000-08-31	2002-08-01	Sanner Mark A.	Pyrazole derivatives
EP1313710A1 (en) *	2000-08-31	2003-05-28	Pfizer Products Inc.	Pyrazole derivatives and their use as protein kinase inhibitors
US6455559B1 (en) *	2001-07-19	2002-09-24	Pharmacia Italia S.P.A.	Phenylacetamido-pyrazole derivatives, process for their preparation and their use as antitumor agents
AU2002215053A1 (en) *	2000-11-27	2002-06-24	Pharmacia Italia S.P.A.	Phenylacetamido- pyrazole derivatives and their use as antitumor agents
NZ527767A (en) *	2001-01-26	2004-11-26	Pharmacia Italia S	Chromane derivatives, process for their preparation and their use as antitumor agents
CA2438813C (en) *	2001-03-02	2008-07-29	F. Hoffmann-La Roche Ag	Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as ip antagonists
SE0100902D0 (sv)	2001-03-15	2001-03-15	Astrazeneca Ab	Compounds
SE0100903D0 (sv) *	2001-03-15	2001-03-15	Astrazeneca Ab	Compounds
US6727364B2 (en)	2001-04-30	2004-04-27	The Procter & Gamble Company	Triazole compounds useful in treating diseases associated with unwanted cytokine activity
US6787555B2 (en) *	2001-04-30	2004-09-07	The Procter & Gamble Company	Triazole compounds useful in treating diseases associated with unwanted cytokine activity
ES2333412T3 (es)	2001-05-25	2010-02-22	Bristol-Myers Squibb Company	Derivados de hidantoina como inhibidores de metaloproteinasas de matriz.
DE10148617A1 (de) *	2001-09-25	2003-04-24	Schering Ag	Substituierte N-(1,4,5,6-Tetrahydro-cyclopentapyrazol-3-yl)-Derivate, deren Herstellung und Verwendung als Arzneimittel
DE10148618B4 (de) *	2001-09-25	2007-05-03	Schering Ag	Substituierte N-(1,4,5,6-Tetrahydro-cyclopentapyrazol-3-yl)-Derivate, deren Herstellung und Verwendung als Arzneimittel
DE60233420D1 (de) *	2001-09-27	2009-10-01	Equispharm Co Ltd	Fumagillolderivate und verfahren zu deren herstellung
SE0103710D0 (sv)	2001-11-07	2001-11-07	Astrazeneca Ab	Compounds
US7514406B2 (en) *	2001-11-27	2009-04-07	Fred Hutchinson Cancer Research Center	Methods for inhibiting deacetylase activity
SE0202539D0 (sv)	2002-08-27	2002-08-27	Astrazeneca Ab	Compounds
GB0221246D0 (en) *	2002-09-13	2002-10-23	Astrazeneca Ab	Compounds
US6593477B1 (en)	2002-10-29	2003-07-15	Eastman Kodak Company	Synthesis of 3-acylaminopyrazoles
MXPA05006196A (es) *	2002-12-10	2006-01-27	Virochem Pharma Inc	Compuestos y metodos para el tratamiento o prevencion de infecciones por flavivirus.
UA81790C2 (uk)	2002-12-19	2008-02-11	Фармация Италия С.П.А.	Заміщені піролопіразольні похідні як інгібітори кінази
WO2004063194A1 (en) *	2003-01-06	2004-07-29	Eli Lilly And Company	Heteroaryl compounds
PL378117A1 (pl) *	2003-02-11	2006-03-06	Prosidion Limited	Tricyklopodstawione związki amidowe
EP1610776A4 (en) *	2003-03-27	2007-03-28	Merck & Co Inc	OPHTHALMIC COMPOSITIONS FOR THE TREATMENT OF OCCULAR HYPERTONIA
SE0301446D0 (sv)	2003-05-16	2003-05-16	Astrazeneca Ab	New Compounds
KR101084871B1 (ko)	2003-05-22	2011-11-21	네르비아노 메디칼 사이언시스 에스.알.엘.	피라졸로-퀴나졸린 유도체, 그의 제조 방법 및 상기유도체의 키나제 저해제로서의 용도
EP1633350B1 (en)	2003-06-05	2012-10-03	Elan Pharmaceuticals, Inc.	Acylated amino acid amidyl pyrazoles and related compounds
US7141568B2 (en)	2003-07-09	2006-11-28	Pfizer Italia S.R.L.	Pyrrolo[3,4-c]pyrazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
CN102060806A (zh)	2003-09-11	2011-05-18	iTherX药品公司	细胞因子抑制剂
ATE443701T1 (de) *	2004-01-16	2009-10-15	Wyeth Corp	Heterocyclische, ein azol enthaltende sulfonamidinhibitoren der beta-amyloid-produktion
WO2005072731A1 (en) *	2004-01-29	2005-08-11	X-Ceptor Therapeutics, Inc.	3-phenyl-n- ((1, 3, 4) thiadiazol-2-yl) -acrylamide derivatives and related compounds as modulators of estrogen-related receptors for the treatment of e.g. cancer, rheumatoid arthritis or neurological disorders
WO2005075435A1 (en) *	2004-01-30	2005-08-18	Vertex Pharmaceuticals Incorporated	Modulators of atp-binding cassette transporters
US7977322B2 (en)	2004-08-20	2011-07-12	Vertex Pharmaceuticals Incorporated	Modulators of ATP-binding cassette transporters
TW200526204A (en)	2004-02-03	2005-08-16	Pharmacia Italia Spa	1h-thieno[2,3-c]pyrazole derivatives useful as kinase inhibitors
WO2005118543A1 (ja) *	2004-06-03	2005-12-15	Ono Pharmaceutical Co., Ltd.	キナーゼ阻害薬およびその用途
US7648992B2 (en)	2004-07-05	2010-01-19	Astrazeneca Ab	Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401762D0 (sv) *	2004-07-05	2004-07-05	Astrazeneca Ab	Novel compounds
WO2006058923A1 (en)	2004-12-03	2006-06-08	Novo Nordisk A/S	Heteroaromatic glucokinase activators
SE0403085D0 (sv)	2004-12-17	2004-12-17	Astrazeneca Ab	Novel componds
SE0403086D0 (sv)	2004-12-17	2004-12-17	Astrazeneca Ab	Compounds
US7361672B2 (en) *	2004-12-23	2008-04-22	Hoffmann-La Roche Inc.	Heteroarylacetamide inhibitors of factor Xa
FR2880540B1 (fr) *	2005-01-13	2008-07-11	Aventis Pharma Sa	Utilisation de derives de la purine comme inhibiteurs de la proteine hsp90
TWI359149B (en)	2005-07-11	2012-03-01	Mitsubishi Tanabe Pharma Corp	An oxime derivative and preparations thereof
US7943654B2 (en)	2005-07-19	2011-05-17	Nerviano Medical Sciences S.R.L.	1H-thieno[2,3-c]pyrazole compounds useful as kinase inhibitors
NZ566744A (en) *	2005-08-29	2011-04-29	Gerard M Housey	Theramutein modulators
UY30048A1 (es)	2005-12-23	2007-07-31	Astrazeneca Ab	Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones
WO2007081966A2 (en) *	2006-01-09	2007-07-19	University Of Southern California	Small molecules for treating cancer and abnormal cell proliferation disorders
WO2007095383A2 (en) *	2006-02-15	2007-08-23	Myriad Genetics, Inc.	Prodrugs
UY30183A1 (es) *	2006-03-02	2007-10-31	Astrazeneca Ab	Derivados de quinolina
US8211925B2 (en)	2006-04-28	2012-07-03	Transtech Pharma, Inc.	Benzamide glucokinase activators
JP2009535388A (ja) *	2006-05-03	2009-10-01	アストラゼネカアクチボラグ	ピラゾール誘導体、及びそのｐｉ３ｋ阻害薬としての使用
JP2009543768A (ja) *	2006-07-14	2009-12-10	アステックス・セラピューティクス・リミテッド	医薬組み合わせ
TWI433839B (zh)	2006-08-11	2014-04-11	Neomed Inst	新穎的苯并咪唑衍生物290
TW200831488A (en) *	2006-11-29	2008-08-01	Astrazeneca Ab	Novel compounds
US7737149B2 (en)	2006-12-21	2010-06-15	Astrazeneca Ab	N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof
WO2008084873A1 (ja) *	2007-01-10	2008-07-17	Mitsubishi Tanabe Pharma Corporation	オキシム誘導体
EP2105435A4 (en) *	2007-01-10	2011-06-15	Mitsubishi Tanabe Pharma Corp	Hydrazone derivative
CA2679185A1 (en)	2007-02-28	2008-09-04	Advinus Therapeutics Private Limited	2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application
KR100923540B1 (ko) *	2007-11-23	2009-10-27	한국과학기술연구원	5-아실하이드라진카르보닐-3,4-디치환 피라졸 유도체 및이의 제조방법
EA201100030A1 (ru) *	2008-06-19	2011-08-30	Астразенека Аб	Пиразольные соединения 436
EA021306B1 (ru)	2008-07-10	2015-05-29	ФАРМА АйПи ДЖЕНЕРАЛ ИНКОРПОРЕЙТЕД АССОШИЭЙШН	Ингибитор stat3, содержащий хинолинкарбоксамидное производное в качестве активного ингредиента
JP5683462B2 (ja)	2008-07-24	2015-03-11	ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ	オーロラキナーゼ阻害剤および抗増殖剤を含む治療用組み合わせ
US8557983B2 (en)	2008-12-04	2013-10-15	Abbvie Inc.	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US20100160322A1 (en)	2008-12-04	2010-06-24	Abbott Laboratories	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US8563735B2 (en)	2008-12-05	2013-10-22	Abbvie Inc.	Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
US8586754B2 (en)	2008-12-05	2013-11-19	Abbvie Inc.	BCL-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases
EP3666758A1 (en) *	2008-12-05	2020-06-17	AbbVie Inc.	Process for the preparation of a sulfonamide derivative
UA106740C2 (uk) *	2009-01-30	2014-10-10	Глаксосмітклайн Ллс	Кристалічний гідрохлорид n-{(1s)-2-аміно-1-[(3-фторфеніл)метил]етил}-5-хлор-4-(4-хлор-1-метил-1h-піразол-5-іл)-2-тіофенкарбоксаміду
US20120045459A1 (en) *	2009-05-05	2012-02-23	Van Andel Research Institute	Methods for Treating Autophagy-Related Disorders
EP2467137A1 (en) *	2009-08-19	2012-06-27	Ambit Biosciences Corporation	Biaryl compounds and methods of use thereof
EP2947073B1 (en) *	2009-10-22	2019-04-03	Fibrotech Therapeutics Pty Ltd	Fused ring analogues of anti-fibrotic agents
CN102711749A (zh) *	2009-11-05	2012-10-03	莱西肯医药有限公司	用于癌症治疗的色氨酸羟化酶抑制剂
RU2639876C2 (ru)	2010-03-30	2017-12-25	Версеон Корпорейшн	Мультизамещенные ароматические соединения в качестве ингибиторов тромбина
AU2011265047B2 (en)	2010-06-07	2014-10-23	Novomedix, Llc	Furanyl compounds and the use thereof
WO2011158108A2 (en)	2010-06-16	2011-12-22	Purdue Pharma L.P.	Aryl substituted indoles and the use thereof
CN105360132A (zh) *	2010-11-03	2016-03-02	陶氏益农公司	杀虫组合物和与其相关的方法
JP6097998B2 (ja) *	2010-12-16	2017-03-22	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ロイコトリエン生成のビアリールアミドインヒビター
JP5980225B2 (ja)	2010-12-17	2016-08-31	ナーヴィアノメディカルサイエンシズエス．アール．エル．	キナーゼ阻害剤としての置換ピラゾロ−キナゾリン誘導体
FR2978441A1 (fr) *	2011-07-25	2013-02-01	Diverchim	Nouveaux analogues de ceramides, leurs procedes de preparation et leurs applications dans les compositions pharmaceutiques et cosmetiques
AR087701A1 (es) *	2011-08-31	2014-04-09	Japan Tobacco Inc	Derivados de pirazol con actividad inhibidora de sglt1
ES2882807T3 (es) *	2011-09-16	2021-12-02	Novartis Ag	Heterociclil carboxamidas N-sustituidas
ES2899850T3 (es)	2011-10-26	2022-03-15	Corteva Agriscience Llc	Composiciones plaguicidas y procedimientos relacionados con las mismas
MX2014013069A (es)	2012-04-27	2015-07-06	Dow Agrosciences Llc	Composiciones plaguicidas y procesos relacionados.
US9282739B2 (en)	2012-04-27	2016-03-15	Dow Agrosciences Llc	Pesticidal compositions and processes related thereto
US9708288B2 (en)	2012-04-27	2017-07-18	Dow Agrosciences Llc	Pesticidal compositions and processes related thereto
US20140179712A1 (en)	2012-12-21	2014-06-26	Astrazeneca Ab	Pharmaceutical formulation of n-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2h-pyrazol-3-yl]-4-[(3r,5s)-3,5-dimethylpiperazin-1-yl]benzamide
CN103936637B (zh) *	2013-01-18	2016-04-06	北京大学	E-3,4-二羟苯乙烯基亚砜类化合物的制备方法及其作为神经保护药物的应用
MX373964B (es)	2013-03-15	2020-07-13	Verseon Corp	Compuestos aromaticos multisustituidos como inhibidores de serina proteasa.
US8937071B2 (en)	2013-03-15	2015-01-20	Glaxosmithkline Intellectual Property Development Limited	Compounds as rearranged during transfection (RET) inhibitors
US9951025B2 (en)	2013-03-15	2018-04-24	Verseon Corporation	Halogenopyrazoles as inhibitors of thrombin
EP2970191B1 (en)	2013-03-15	2016-12-21	GlaxoSmithKline Intellectual Property Development Limited	Pyridine derivatives as rearranged during transfection (ret) kinase inhibitors
US10435364B2 (en)	2013-04-17	2019-10-08	Albert Ludwigs Universität Freiburg	Compounds for use as bromodomain inhibitors
CN103265535B (zh) *	2013-05-14	2015-06-17	浙江医药高等专科学校	抗肿瘤化合物、其制备方法和用途
EP3039021A1 (en)	2013-08-30	2016-07-06	Ambit Biosciences Corporation	Biaryl acetamide compounds and methods of use thereof
JP2016536295A (ja)	2013-10-17	2016-11-24	ダウアグロサイエンシィズエルエルシー	有害生物防除性化合物の製造方法
CA2926095A1 (en)	2013-10-17	2015-04-23	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
CN105636440A (zh)	2013-10-17	2016-06-01	美国陶氏益农公司	制备杀虫化合物的方法
MX2016004942A (es)	2013-10-17	2016-06-28	Dow Agrosciences Llc	Procesos para la preparacion de compuestos plaguicidas.
EP3057431A4 (en)	2013-10-17	2017-04-05	Dow AgroSciences LLC	Processes for the preparation of pesticidal compounds
JP6487426B2 (ja)	2013-10-17	2019-03-20	ダウアグロサイエンシィズエルエルシー	有害生物防除化合物の調製法
CN105636446B (zh) *	2013-10-17	2018-07-13	美国陶氏益农公司	制备杀虫化合物的方法
CA2927195A1 (en)	2013-10-22	2015-04-30	Dow Agrosciences Llc	Synergistic pesticidal compositions and related methods
KR20160074633A (ko)	2013-10-22	2016-06-28	다우 아그로사이언시즈 엘엘씨	상승작용적 살충 조성물 및 관련 방법
KR20160074635A (ko)	2013-10-22	2016-06-28	다우 아그로사이언시즈 엘엘씨	상승작용적 살충 조성물 및 관련 방법
AR098096A1 (es)	2013-10-22	2016-05-04	Dow Agrosciences Llc	Composiciones plaguicidas sinérgicas y métodos relacionados
KR102286233B1 (ko)	2013-10-22	2021-08-06	코르테바 애그리사이언스 엘엘씨	살충 조성물 및 관련 방법
TW201519782A (zh)	2013-10-22	2015-06-01	Dow Agrosciences Llc	殺蟲組成物及相關方法（五）
EP3060051A4 (en)	2013-10-22	2017-04-05	Dow AgroSciences LLC	Synergistic pesticidal compositions and related methods
CN105658062A (zh)	2013-10-22	2016-06-08	美国陶氏益农公司	协同杀虫组合物和相关方法
KR20160074582A (ko)	2013-10-22	2016-06-28	다우 아그로사이언시즈 엘엘씨	상승작용적 살충 조성물 및 관련 방법
CA2926345A1 (en)	2013-10-22	2015-04-30	Dow Agrosciences Llc	Synergistic pesticidal compositions and related methods
EP3060047A4 (en)	2013-10-22	2017-04-26	Dow AgroSciences, LLC	Pesticidal compositions and related methods
CA2926101C (en)	2013-10-22	2022-05-31	Dow Agrosciences Llc	Pesticidal compositions and related methods
AU2014340430B2 (en)	2013-10-22	2017-05-25	Dow Agrosciences Llc	Pesticidal compositions and related methods
EP3060046A4 (en)	2013-10-22	2017-07-26	Dow AgroSciences LLC	Pesticidal compositions and related methods
RU2016119571A (ru)	2013-10-22	2017-11-28	ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи	Синергетические пестицидные композиции и связанные с ними способы
CN105848481A (zh)	2013-10-22	2016-08-10	美国陶氏益农公司	协同杀虫组合物和相关方法
WO2015061147A1 (en)	2013-10-22	2015-04-30	Dow Agrosciences Llc	Synergistic pesticidal compositions and related methods
WO2015143653A1 (en) *	2014-03-26	2015-10-01	Merck Sharp & Dohme Corp.	TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF
EP3186230A4 (en)	2014-07-31	2018-01-10	Dow AgroSciences, LLC	Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CA2954345A1 (en)	2014-07-31	2016-02-04	Dow Agrosciences Llc	Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
BR112017000418A2 (pt)	2014-07-31	2017-11-07	Dow Agrosciences Llc	processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina
EP3183238A4 (en)	2014-08-19	2018-01-10	Dow AgroSciences LLC	Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
UA123084C2 (uk)	2014-09-10	2021-02-17	Глаксосмітклайн Інтеллектьюел Проперті Девелопмент Лімітед	Сполуки як інгібітори кінази, реаранжованої під час трансфекції (ret)
UA122213C2 (uk)	2014-09-10	2020-10-12	Глаксосмітклайн Інтеллектьюел Проперті Девелопмент Лімітед	Сполуки як інгібітори кінази, реаранжованої під час трансфекції (ret)
BR112017004613A2 (pt)	2014-09-12	2017-12-05	Dow Agrosciences Llc	processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina
US10189810B2 (en)	2014-09-17	2019-01-29	Verseon Corporation	Pyrazolyl-substituted pyridone compounds as serine protease inhibitors
GB201416513D0 (en) *	2014-09-18	2014-11-05	Astex Therapeutics Ltd And Cancer Res Technology Ltd	Pharmaceutical compounds
SI3261639T1 (sl)	2015-02-27	2023-01-31	Verseon International Corporation	Substituirane pirazolne spojine kot zaviralci serinskih proteaz
EP3268000B1 (en)	2015-03-09	2021-08-04	Aurigene Discovery Technologies Limited	Pyrazolo[1,5-a][1,3,5]triazine and pyrazolo[1,5-a]pyrimidine derivatives as cdk inhibitors
CA2983927A1 (en)	2015-05-06	2016-11-10	The Regents Of The University Of California	K-ras modulators
DK3302448T3 (da)	2015-06-04	2024-02-05	Aurigene Oncology Ltd	Erstattede heterocyclylafledninger som cdk-inhibitore
CN110023310B (zh) *	2016-08-12	2024-05-10	阿西纳斯公司	用于调节激酶级联的联芳组合物和方法
WO2018125817A1 (en)	2016-12-29	2018-07-05	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
CN110114349B (zh) *	2016-12-29	2022-03-15	埃尼奥制药公司	作为抗病毒剂的噻吩衍生物
US10100033B2 (en)	2016-12-29	2018-10-16	Dow Agrosciences Llc	Processes for the preparation of pesticidal compounds
AU2018215089C1 (en)	2017-02-03	2022-09-22	Certa Therapeutics Pty. Ltd.	Anti-fibrotic compounds
WO2018172852A1 (en) *	2017-03-21	2018-09-27	Arbutus Biopharma Corporation	Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same
SG11201909570PA (en) *	2017-04-20	2019-11-28	Univ California	K-ras modulators
CN111727042A (zh)	2017-12-06	2020-09-29	仁新医药私人有限公司	微管蛋白抑制剂
JP7184383B2 (ja) *	2018-02-01	2022-12-06	ザ・ユニバーシティ・オブ・シドニー	抗癌性化合物
CA3095987A1 (en) *	2018-04-04	2019-10-10	Aurigene Discovery Technologies Limited	Substituted pyrazole derivatives as selective cdk12/13 inhibitors
US11084825B2 (en)	2018-12-31	2021-08-10	Biomea Fusion, Llc	Substituted pyridines as irreversible inhibitors of menin-MLL interaction
US11174263B2 (en)	2018-12-31	2021-11-16	Biomea Fusion, Inc.	Inhibitors of menin-MLL interaction
CA3166455A1 (en) *	2020-01-29	2021-08-05	Neville John ANTHONY	Heterocyclic compounds useful for modulating baf complexes
CN111793034B (zh) *	2020-07-24	2021-11-19	华中科技大学	苯并咪唑盐衍生物与制备抗肿瘤药物的应用
JP2023545588A (ja) *	2020-10-16	2023-10-30	ツェーエムエム－フォルシュングスツェントルムフュアモレクラレメディツィンゲーエムベーハー	ヘテロ環式カリンｒｉｎｇユビキチンリガーゼ化合物及びその使用
TW202229268A (zh) *	2020-12-22	2022-08-01	大陸商上海拓界生物醫藥科技有限公司	Ｃｄｋ２抑制劑及其製備方法
WO2023018825A1 (en)	2021-08-11	2023-02-16	Biomea Fusion, Inc.	Covalent inhibitors of menin-mll interaction for diabetes mellitus
MX2024002189A (es)	2021-08-20	2024-06-11	Biomea Fusion Inc	Forma cristalina de n-[4-[4-(4-morfolinil)-7h-pirrolo[2,3-d]pirimi din-6-il]fenil]-4-[[3(r)-[(1-oxo)-2-propen-1-il)amino]-1-piperidi nil]metil]-2-piridinacarboxamida, un inhibidor irreversible de menina-mll para el tratamiento del cancer.
WO2023107714A2 (en) *	2021-12-10	2023-06-15	Prothena Biosciences Limited	Methods for treating neurological disorders
WO2023203174A1 (en) *	2022-04-20	2023-10-26	Proxygen Gmbh	Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
TW202430528A (zh)	2023-01-18	2024-08-01	美商拜歐米富士恩股份有限公司	Ｎ－［４－［４－（４－嗎啉基）－７ｈ－吡咯並［２，３－ｄ］嘧啶－６－基］苯基］－４－［［３（ｒ）－［（１－氧代－２－丙烯－１－基）氨基］－１－哌啶基］甲基］－２－吡啶甲醯胺的結晶形式作為ｍｅｎｉｎ－ｍｌｌ相互作用的共價抑制劑
CN116496151B (zh) *	2023-04-26	2024-08-23	长沙医学院	一种利用Catellani策略制备芴酮衍生物的方法
CN118221668A (zh) *	2024-03-19	2024-06-21	华南农业大学	一种含2-氨基-1,3,4-噻二唑的吲哚美辛衍生物及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5162360A (en)	1991-06-24	1992-11-10	Warner-Lambert Company	2-heteroatom containing urea and thiourea ACAT inhibitors
JPH10509708A (ja)	1994-11-10	1998-09-22	コアセラピューティクス，インコーポレイティド	プロテイン・キナーゼのインヒビターとして有用な医薬ピラゾール組成物
AU5135998A (en)	1996-12-03	1998-06-29	Banyu Pharmaceutical Co., Ltd.	Novel urea derivatives
AU7726898A (en)	1997-05-22	1998-12-11	G.D. Searle & Co.	Pyrazole derivatives as p38 kinase inhibitors
CA2315720A1 (en)	1997-12-22	1999-07-01	Bayer Corporation	Inhibition of p38 kinase activity using substituted heterocyclic ureas
RU2265597C2 (ru)	1997-12-22	2005-12-10	Байер Копэрейшн	Арил- и гетероарилзамещенные гетероциклические производные мочевины, способ ингибирования киназы raf и фармацевтическая композиция
HUP0203542A3 (en) *	1999-08-12	2003-07-28	Upjohn Co	3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
US6455559B1 (en) *	2001-07-19	2002-09-24	Pharmacia Italia S.P.A.	Phenylacetamido-pyrazole derivatives, process for their preparation and their use as antitumor agents

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CA2383555A1 (en)	2001-02-22
DK1202733T3 (da)	2005-10-31
HUP0203542A3 (en)	2003-07-28
AR026122A1 (es)	2003-01-29
EP1202733B1 (en)	2005-10-05
NZ517237A (en)	2004-02-27
EE200200065A (et)	2003-04-15
OA12046A (en)	2006-05-02
DE60023012D1 (de)	2006-02-16
WO2001012189A1 (en)	2001-02-22
KR20020060160A (ko)	2002-07-16
EA200200248A1 (ru)	2002-08-29
MXPA02001498A (es)	2003-07-21
NO20020684L (no)	2002-04-03
BR0013143A (pt)	2002-06-11
HUP0203542A2 (en)	2003-05-28
EA005373B1 (ru)	2005-02-24
MA25493A1 (fr)	2002-07-01
YU9602A (sh)	2004-11-25
EP1202733A4 (en)	2003-05-14
ES2249270T3 (es)	2006-04-01
AU4971400A (en)	2001-03-13
SK1812002A3 (en)	2003-02-04
PL353455A1 (en)	2003-11-17
US6218418B1 (en)	2001-04-17
EP1202733A1 (en)	2002-05-08
PE20010130A1 (es)	2001-02-01
CA2383555C (en)	2009-02-17
DE60023012T2 (de)	2006-07-20
WO2001012189A8 (en)	2001-08-02
HRP20020128A2 (en)	2003-04-30
BG106480A (en)	2002-09-30
IS6265A (is)	2002-02-11
AP2002002442A0 (en)	2002-03-31
ATE305782T1 (de)	2005-10-15
CZ2002422A3 (cs)	2002-11-13
IL147923A0 (en)	2002-08-14
HK1046866A1 (zh)	2003-01-30
US7034049B1 (en)	2006-04-25
CN1373662A (zh)	2002-10-09
GEP20053476B (en)	2005-03-25
JP2003507329A (ja)	2003-02-25
ZA200201511B (en)	2003-05-28

Publication	Publication Date	Title
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