NO20013478D0 - Nye aralkylaminer av spirofluorpyridiner som er nyttige i terapi - Google Patents

Nye aralkylaminer av spirofluorpyridiner som er nyttige i terapi

Info

Publication number: NO20013478D0
Authority: NO; Norway
Prior art keywords: spirofluoropyridines; aralkylamines; therapy; useful; new
Prior art date: 1999-01-15

Application number

NO20013478A

Other languages

English (en)

Other versions

NO20013478L (no

Inventor

Iii James Loch

George Mullen

Eifion Phillips

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-15

Filing date

2001-07-13

Publication date

2001-07-13

2001-07-13 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2001-07-13 Publication of NO20013478D0 publication Critical patent/NO20013478D0/no

2001-09-14 Publication of NO20013478L publication Critical patent/NO20013478L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Medicinal Chemistry (AREA)
Neurology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO20013478A 1999-01-15 2001-07-13 Nye aralkylaminer av spirofuropyridiner som er nyttige i terapi NO20013478L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9900100A SE9900100D0 (sv)	1999-01-15	1999-01-15	New compounds
PCT/SE1999/002478 WO2000042044A1 (en)	1999-01-15	1999-12-23	Novel aralkyl amines of spirofuropyridines useful in therapy

Publications (2)

Publication Number	Publication Date
NO20013478D0 true NO20013478D0 (no)	2001-07-13
NO20013478L NO20013478L (no)	2001-09-14

Family

ID=20414101

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20013478A NO20013478L (no)	1999-01-15	2001-07-13	Nye aralkylaminer av spirofuropyridiner som er nyttige i terapi

Country Status (34)

Country	Link
US (2)	US6995167B2 (no)
EP (1)	EP1147114B1 (no)
JP (1)	JP2002534525A (no)
KR (1)	KR100660496B1 (no)
CN (1)	CN1132837C (no)
AR (1)	AR022283A1 (no)
AT (1)	ATE240960T1 (no)
AU (1)	AU775433B2 (no)
BR (1)	BR9916906A (no)
CA (1)	CA2359990A1 (no)
CZ (1)	CZ20012554A3 (no)
DE (1)	DE69908185T2 (no)
DK (1)	DK1147114T3 (no)
EE (1)	EE04528B1 (no)
ES (1)	ES2200590T3 (no)
HK (1)	HK1040517B (no)
HU (1)	HUP0200513A3 (no)
ID (1)	ID30034A (no)
IL (1)	IL144266A0 (no)
IS (1)	IS6000A (no)
MY (1)	MY118109A (no)
NO (1)	NO20013478L (no)
NZ (1)	NZ512733A (no)
PT (1)	PT1147114E (no)
RU (1)	RU2233282C2 (no)
SA (1)	SA00200987B1 (no)
SE (1)	SE9900100D0 (no)
SI (1)	SI1147114T1 (no)
SK (1)	SK9932001A3 (no)
TR (1)	TR200102042T2 (no)
TW (2)	TWI227237B (no)
UA (1)	UA71598C2 (no)
WO (1)	WO2000042044A1 (no)
ZA (1)	ZA200105527B (no)

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SE9900100D0 (sv)	1999-01-15	1999-01-15	Astra Ab	New compounds
FR2790474B1 (fr) *	1999-03-05	2001-04-06	Synthelabo	Derives de pyridopyranoazepines, leur preparation et leur application en therapeutique
US6569865B2 (en)	2001-06-01	2003-05-27	Astrazeneca Ab	Spiro 1-azabicyclo[2.2.2]octane-3,2′(3′h)-furo[2,3-b]pyridine
CN1294136C (zh) *	2001-06-01	2007-01-10	阿斯特拉曾尼卡有限公司	用于治疗的烟碱乙酰胆碱受体新型配体
KR100614900B1 (ko) *	2001-10-02	2006-08-25	파마시아 앤드 업존 캄파니 엘엘씨	질병의 치료를 위한 아자비시클릭-치환된 융합-헤테로아릴화합물
DE10164139A1 (de)	2001-12-27	2003-07-10	Bayer Ag	2-Heteroarylcarbonsäureamide
CN1325500C (zh)	2002-04-18	2007-07-11	阿斯特拉曾尼卡有限公司	呋喃基化合物
MXPA04010190A (es) *	2002-04-18	2005-02-03	Astrazeneca Ab	Compuestos heterociclicos.
AU2003224545B2 (en)	2002-04-18	2009-08-13	Astrazeneca Ab	Thienyl compounds
EP1531820A1 (en)	2002-08-30	2005-05-25	Memory Pharmaceuticals Corporation	Anabaseine derivatives useful in the treatment of neurodegenerative diseases
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GB0220581D0 (en)	2002-09-04	2002-10-09	Novartis Ag	Organic Compound
SK288115B6 (sk)	2002-09-25	2013-09-03	Memory Pharmaceuticals Corporation	Indazoles, pharmaceutical compositions comprising them and their use
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PE20060437A1 (es)	2004-06-18	2006-06-08	Novartis Ag	COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en)	2004-07-14	2004-08-18	Novartis Ag	Organic compounds
MY145694A (en) *	2005-04-11	2012-03-30	Xenon Pharmaceuticals Inc	Spiroheterocyclic compounds and their uses as therapeutic agents
GB0521508D0 (en)	2005-10-21	2005-11-30	Novartis Ag	Organic compounds
US8316104B2 (en)	2005-11-15	2012-11-20	California Institute Of Technology	Method and apparatus for collaborative system
GB0525672D0 (en)	2005-12-16	2006-01-25	Novartis Ag	Organic compounds
GB0525673D0 (en)	2005-12-16	2006-01-25	Novartis Ag	Organic compounds
RU2448111C2 (ru) *	2006-08-21	2012-04-20	Дженентек, Инк.	Соединения азабензофуранила и способ их применения
CL2008000119A1 (es)	2007-01-16	2008-05-16	Wyeth Corp	Compuestos derivados de pirazol, antagonistas del receptor nicotinico de acetilcolina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como demencia senil, alzheimer y esquizofrenia.
SA08290475B1 (ar)	2007-08-02	2013-06-22	Targacept Inc	(2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
RS52703B (sr)	2008-06-20	2013-08-30	Astrazeneca Ab	Derivat dibenzotiazepina i njegova upotreba
CN103664973B (zh)	2008-10-17	2017-04-19	泽农医药公司	螺羟吲哚化合物及其作为治疗剂的用途
MY173229A (en)	2008-11-19	2020-01-07	Forum Pharmaceuticals Inc	Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
TW201031664A (en)	2009-01-26	2010-09-01	Targacept Inc	Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
RU2011150248A (ru) *	2009-05-11	2013-06-20	Энвиво Фармасьютикалз, Инк.	Лечение когнитивных расстройств с определенными рецепторами альфа-7 никотиновой кислоты в комбинации с ингибиторами ацетилхолинэстеразы
AR077252A1 (es)	2009-06-29	2011-08-10	Xenon Pharmaceuticals Inc	Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos
NZ599334A (en) *	2009-10-14	2014-03-28	Xenon Pharmaceuticals Inc	Synthetic methods for spiro-oxindole compounds
US9504671B2 (en)	2010-02-26	2016-11-29	Xenon Pharmaceuticals Inc.	Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
PT3029039T (pt)	2010-05-17	2017-11-28	Forum Pharmaceuticals Inc	Formulações farmacêuticas que compreendem formas cristalinas de cloridrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo(b)tiofeno-2-carboxamida mono-hidratado
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JO3115B1 (ar)	2011-08-22	2017-09-20	Takeda Pharmaceuticals Co	مركبات بيريدازينون واستخدامها كمثبطات daao
KR20150002794A (ko)	2012-04-12	2015-01-07	제논 파마슈티칼스 인크.	치료제로서 유용한 스파이로-옥시인돌 화합물을 위한 비대칭적 합성
EP2846796A4 (en)	2012-05-08	2015-10-21	Forum Pharmaceuticals Inc	METHODS OF MAINTAINING, PROCESSING OR ENHANCING COGNITIVE FUNCTION
GB201209587D0 (en)	2012-05-30	2012-07-11	Takeda Pharmaceutical	Therapeutic compounds
JP6478923B2 (ja)	2013-02-07	2019-03-06	ヘプタレスセラピューティクスリミテッドＨｅｐｔａｒｅｓＴｈｅｒａｐｅｕｔｉｃｓＬｉｍｉｔｅｄ	ムスカリンｍ４受容体アゴニストとしてのピペリジン−１−イル及びアゼピン−１−イルカルボキシレート
EA029430B1 (ru)	2013-06-21	2018-03-30	Такеда Фармасьютикл Компани Лимитед	Производные 1-сульфонилпиперидина в качестве модуляторов рецепторов прокинетицина
GB201314286D0 (en)	2013-08-08	2013-09-25	Takeda Pharmaceutical	Therapeutic Compounds
GB201318222D0 (en)	2013-10-15	2013-11-27	Takeda Pharmaceutical	Novel compounds
GB201320905D0 (en)	2013-11-27	2014-01-08	Takeda Pharmaceutical	Therapeutic compounds
TW201613864A (en)	2014-02-20	2016-04-16	Takeda Pharmaceutical	Novel compounds
WO2016127068A1 (en)	2015-02-05	2016-08-11	Teva Pharmaceuticals International Gmbh	Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound
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GB201619514D0 (en)	2016-11-18	2017-01-04	Takeda Pharmaceuticals Co	Novel compounds
JP2021138648A (ja)	2020-03-04	2021-09-16	武田薬品工業株式会社	経口固形製剤

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SE9900100D0 (sv)	1999-01-15	1999-01-15	Astra Ab	New compounds

1999
- 1999-01-15 SE SE9900100A patent/SE9900100D0/xx unknown
- 1999-12-23 CZ CZ20012554A patent/CZ20012554A3/cs unknown
- 1999-12-23 IL IL14426699A patent/IL144266A0/xx unknown
- 1999-12-23 DK DK99967044T patent/DK1147114T3/da active
- 1999-12-23 ES ES99967044T patent/ES2200590T3/es not_active Expired - Lifetime
- 1999-12-23 HK HK02102161.7A patent/HK1040517B/en not_active IP Right Cessation
- 1999-12-23 HU HU0200513A patent/HUP0200513A3/hu unknown
- 1999-12-23 BR BR9916906-1A patent/BR9916906A/pt not_active Application Discontinuation
- 1999-12-23 UA UA2001085777A patent/UA71598C2/uk unknown
- 1999-12-23 CN CN998164224A patent/CN1132837C/zh not_active Expired - Fee Related
- 1999-12-23 RU RU2001122812/04A patent/RU2233282C2/ru not_active IP Right Cessation
- 1999-12-23 JP JP2000593611A patent/JP2002534525A/ja active Pending
- 1999-12-23 AT AT99967044T patent/ATE240960T1/de not_active IP Right Cessation
- 1999-12-23 ID IDW00200101529A patent/ID30034A/id unknown
- 1999-12-23 EE EEP200100370A patent/EE04528B1/xx not_active IP Right Cessation
- 1999-12-23 PT PT99967044T patent/PT1147114E/pt unknown
- 1999-12-23 NZ NZ512733A patent/NZ512733A/en unknown
- 1999-12-23 CA CA002359990A patent/CA2359990A1/en not_active Abandoned
- 1999-12-23 AU AU23343/00A patent/AU775433B2/en not_active Ceased
- 1999-12-23 EP EP99967044A patent/EP1147114B1/en not_active Expired - Lifetime
- 1999-12-23 US US09/529,654 patent/US6995167B2/en not_active Expired - Fee Related
- 1999-12-23 KR KR1020017008939A patent/KR100660496B1/ko not_active Expired - Fee Related
- 1999-12-23 DE DE69908185T patent/DE69908185T2/de not_active Expired - Fee Related
- 1999-12-23 SI SI9930375T patent/SI1147114T1/xx unknown
- 1999-12-23 WO PCT/SE1999/002478 patent/WO2000042044A1/en not_active Ceased
- 1999-12-23 SK SK993-2001A patent/SK9932001A3/sk unknown
- 1999-12-23 TR TR2001/02042T patent/TR200102042T2/xx unknown
2000
- 2000-01-13 MY MYPI20000100A patent/MY118109A/en unknown
- 2000-01-13 AR ARP000100156A patent/AR022283A1/es not_active Application Discontinuation
- 2000-01-21 TW TW089100989A patent/TWI227237B/zh not_active IP Right Cessation
- 2000-01-21 TW TW093106537A patent/TW200413387A/zh unknown
- 2000-02-21 SA SA00200987A patent/SA00200987B1/ar unknown
2001
- 2001-07-04 ZA ZA200105527A patent/ZA200105527B/en unknown
- 2001-07-12 IS IS6000A patent/IS6000A/is unknown
- 2001-07-13 NO NO20013478A patent/NO20013478L/no not_active Application Discontinuation
2005
- 2005-07-14 US US11/181,098 patent/US7196096B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US7196096B2 (en)	2007-03-27
US6995167B2 (en)	2006-02-07
HK1040517A1 (en)	2002-06-14
RU2233282C2 (ru)	2004-07-27
IS6000A (is)	2001-07-12
SI1147114T1 (en)	2003-12-31
MY118109A (en)	2004-08-30
KR100660496B1 (ko)	2006-12-22
TW200413387A (en)	2004-08-01
EE04528B1 (et)	2005-08-15
IL144266A0 (en)	2002-05-23
HUP0200513A2 (en)	2002-06-29
DE69908185T2 (de)	2004-06-03
BR9916906A (pt)	2001-10-30
EP1147114B1 (en)	2003-05-21
TWI227237B (en)	2005-02-01
CN1132837C (zh)	2003-12-31
EE200100370A (et)	2002-10-15
US20030149065A1 (en)	2003-08-07
TR200102042T2 (tr)	2002-05-21
SE9900100D0 (sv)	1999-01-15
PT1147114E (pt)	2003-10-31
ATE240960T1 (de)	2003-06-15
US20050250802A1 (en)	2005-11-10
SK9932001A3 (en)	2002-04-04
KR20010086167A (ko)	2001-09-08
AR022283A1 (es)	2002-09-04
EP1147114A1 (en)	2001-10-24
HK1040517B (en)	2003-09-05
HUP0200513A3 (en)	2004-07-28
JP2002534525A (ja)	2002-10-15
UA71598C2 (en)	2004-12-15
SA00200987B1 (ar)	2006-11-07
ES2200590T3 (es)	2004-03-01
DE69908185D1 (de)	2003-06-26
CN1337964A (zh)	2002-02-27
AU775433B2 (en)	2004-07-29
NZ512733A (en)	2003-08-29
WO2000042044A1 (en)	2000-07-20
DK1147114T3 (da)	2003-09-15
CA2359990A1 (en)	2000-07-20
CZ20012554A3 (cs)	2002-01-16
AU2334300A (en)	2000-08-01
ID30034A (id)	2001-11-01
NO20013478L (no)	2001-09-14
ZA200105527B (en)	2002-10-04

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