NO20013444D0 - Triazolforbindelser med dopamin-D3-reseptor-affinet - Google Patents

Triazolforbindelser med dopamin-D3-reseptor-affinet

Info

Publication number: NO20013444D0
Authority: NO; Norway
Prior art keywords: dopamine; triazole compounds; receptor affinity; receptor; compounds
Prior art date: 1999-01-12

Application number

NO20013444A

Other languages

English (en)

Other versions

NO20013444L (no

Inventor

Dorothea Starch

Hans-Joerg Treiber

Liliane Unger

Barbara Neumann-Schultz

Kai Blumbach

Dietmar Schoebel

Original Assignee

Basf Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-12

Filing date

2001-07-11

Publication date

2001-07-11

2001-07-11 Application filed by Basf Ag filed Critical Basf Ag

2001-07-11 Publication of NO20013444D0 publication Critical patent/NO20013444D0/no

2001-07-11 Publication of NO20013444L publication Critical patent/NO20013444L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Psychology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Anesthesiology (AREA)
Vascular Medicine (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20013444A 1999-01-12 2001-07-11 Triazolforbindelser med dopamin-D3-reseptor-affinet NO20013444L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19900811		1999-01-12
PCT/EP2000/000175 WO2000042038A1 (de)	1999-01-12	2000-01-12	Triazolverbindungen mit dopamin-3-rezeptoraffinität

Publications (2)

Publication Number	Publication Date
NO20013444D0 true NO20013444D0 (no)	2001-07-11
NO20013444L NO20013444L (no)	2001-07-11

Family

ID=7894006

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20013444A NO20013444L (no)	1999-01-12	2001-07-11	Triazolforbindelser med dopamin-D3-reseptor-affinet
NO20013443A NO20013443L (no)	1999-01-12	2001-07-11	Triazolforbindelser med dopamin-D3-reseptoraktivitet

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20013443A NO20013443L (no)	1999-01-12	2001-07-11	Triazolforbindelser med dopamin-D3-reseptoraktivitet

Country Status (28)

Country	Link
US (3)	US6602867B1 (no)
EP (3)	EP1140908B1 (no)
JP (3)	JP4615125B2 (no)
KR (3)	KR100775720B1 (no)
CN (3)	CN1267430C (no)
AR (3)	AR022229A1 (no)
AT (3)	ATE424398T1 (no)
AU (3)	AU773047B2 (no)
BG (2)	BG65086B1 (no)
BR (2)	BR0007500A (no)
CA (3)	CA2359952A1 (no)
CO (3)	CO5150182A1 (no)
CZ (2)	CZ303926B6 (no)
DE (3)	DE50015802D1 (no)
ES (2)	ES2334326T3 (no)
HK (1)	HK1045311B (no)
HR (1)	HRP20010590A2 (no)
HU (2)	HUP0200522A3 (no)
ID (2)	ID29930A (no)
IL (3)	IL144136A0 (no)
NO (2)	NO20013444L (no)
NZ (2)	NZ512864A (no)
PL (2)	PL201889B1 (no)
SK (2)	SK9852001A3 (no)
TR (2)	TR200102026T2 (no)
TW (1)	TWI274750B (no)
WO (3)	WO2000042037A1 (no)
ZA (2)	ZA200106585B (no)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9810876D0 (en)	1998-05-20	1998-07-22	Smithkline Beecham Plc	Compounds
AU761018B2 (en)	1998-10-08	2003-05-29	Smithkline Beecham Plc	Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents)
TWI274750B (en)	1999-01-12	2007-03-01	Abbott Gmbh & Co Kg	Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
US7229986B2 (en)	2000-05-16	2007-06-12	Takeda Pharmaceutical Company Ltd.	Melanin-concentrating hormone antagonist
KR20030045187A (ko) *	2000-11-14	2003-06-09	스미스클라인비이참피이엘시이	도파민 ｄ₃수용체 조절제 (정신병 치료제)로서 유용한테트라히드로벤즈아제핀 유도체
HU227543B1 (en) *	2001-09-28	2011-08-29	Richter Gedeon Nyrt	N-[4-(2-piperazin- and 2-piperidin-1-yl-ethyl)-cyclohexyl]-sulfon- and sulfamides, process for their preparation, their use and pharmaceutical compositions containing them
GB0130219D0 (en) *	2001-12-18	2002-02-06	Pfizer Ltd	Compounds for the treatment of sexual dysfunction
WO2003062205A1 (en) *	2001-12-21	2003-07-31	Smithkline Beecham P.L.C.	7-sulfonyl-3-benzazepine derivatives as modulators of the dopamine receptor and their use for the treatment of cns disorders
US7314937B2 (en) *	2002-03-21	2008-01-01	Eli Lilly And Company	Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses
MY133587A (en)	2002-05-29	2007-11-30	Glaxo Group Ltd	Aromatic sulfones and their medical use
DE10304870A1 (de) *	2003-02-06	2004-08-19	Abbott Gmbh & Co. Kg	Triazolverbindungen und ihre therapeutische Verwendung
ES2308157T3 (es) *	2003-03-17	2008-12-01	Bayer Healthcare Ag	Disgnosticos y tratamientos para enfermedades asociadas con el receptor de la dopamina d3 (drd3).
US6919342B2 (en)	2003-06-05	2005-07-19	Abbott Gmbh & Co. Kg	Triazole compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor
WO2005051945A1 (en) *	2003-11-20	2005-06-09	Eli Lilly And Company	Heterocyclic compounds as modulators of peroxisome proliferator activated receptors, useful for the treatment and/or prevention of disorders modulated by a ppar
KR20050054084A (ko) *	2003-12-03	2005-06-10	한국전자통신연구원	수신 환경에 기반한 위성 상태 데이터 분배 기능을 가지는위성관제 시스템 및 그 방법
HRP20100114T1 (hr)	2004-02-23	2010-04-30	Glaxo Group Limited	Derivati azabiciklo[3.1.0]heksana korisni kao modulatori dopaminskih receptora d3
EP1737851A1 (en) *	2004-03-08	2007-01-03	Glaxo Group Limited	Tetrahydrobenzazepine derivatives as modulators of dopamine d3 receptors (antipsychotic agents)
WO2005090320A2 (en) *	2004-03-12	2005-09-29	Wyeth	Triazole derivatives and method of using the same to treat hiv infections
GB0412314D0 (en) *	2004-06-02	2004-07-07	Glaxo Group Ltd	Compounds
DE102004027358A1 (de)	2004-06-04	2005-12-29	Abbott Gmbh & Co. Kg	Pyrimidinverbindungen und ihre Verwendung
GB0413879D0 (en) *	2004-06-21	2004-07-21	Glaxo Group Ltd	Compounds
GB0414795D0 (en) *	2004-07-01	2004-08-04	Glaxo Group Ltd	Compounds
ATE452134T1 (de) *	2004-08-09	2010-01-15	Abbott Gmbh & Co Kg	Zur behandlung von auf eine modulation des dopamin-d3-rezeptors ansprechende erkrankungen geeignete 4-piperazinylpyrimidinverbindungen
CA2577060A1 (en) *	2004-08-13	2006-02-23	Amgen Inc.	Substituted benzofused heterocycles
KR20070106989A (ko)	2004-12-02	2007-11-06	애보트 게엠베하 운트 콤파니 카게	도파민 ｄ₃ 수용체의 조정에 반응하는 장애의 치료에적합한 트리아졸 화합물
GB0507602D0 (en)	2005-04-14	2005-05-18	Glaxo Group Ltd	Compounds
GB0507680D0 (en) *	2005-04-15	2005-05-25	Glaxo Group Ltd	Compounds
DE602006017543D1 (de) *	2005-06-14	2010-11-25	Glaxo Group Ltd	Neue verbindungen
CA2618628C (en)	2005-08-18	2014-11-18	Synta Pharmaceuticals Corp.	Triazole compounds that modulate hsp90 activity
JP5237807B2 (ja) *	2005-08-22	2013-07-17	グラクソグループリミテッド	ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体
WO2007028145A2 (en) *	2005-09-02	2007-03-08	Dara Biosciences, Inc.	Agents and methods for reducing protein tyrosine phosphatase 1b activity in the central nervous system
EP2004166A2 (en) *	2006-03-31	2008-12-24	La Jolla Pharmaceutical Company	Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment and prevention of diseases
BRPI0807219A2 (pt) *	2007-02-08	2015-05-26	Synta Pharmaceuticals Corp	Composto de tiazol que modulam a atividade de hsp90
EP2323737A2 (en)	2008-08-08	2011-05-25	Synta Pharmaceuticals Corp.	Triazole compounds that modulate hsp90 activity
US9227944B2 (en)	2008-10-10	2016-01-05	Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China	Dopamine D3 receptor ligands and preparation and medical uses of the same
JP5701213B2 (ja)	2008-10-10	2015-04-15	インスティチュートオブファーマコロジーアンドトキシコロジーアカデミーオブミリタリーメディカルサイエンシズピー．エル．エー．チャイナ	新規なドーパミンｄ３受容体リガンド、その調製及び使用
US9326955B2 (en) *	2008-10-31	2016-05-03	Loyola University Chicago	Combination pharmaceuticals and methods thereof using proteinacious channels as treatments for medical conditions
ES2523766T3 (es) *	2009-12-22	2014-12-01	Cephalon, Inc	Hexahidrocromeno[3,4-b]pirroles sustituidos con afinidad por la familia de los receptores de serotonina (5-HT)
WO2012124744A1 (ja) *	2011-03-14	2012-09-20	大正製薬株式会社	含窒素縮合複素環化合物
EP2855455B1 (en) *	2012-05-30	2017-11-08	F. Hoffmann-La Roche AG	Triazolo compounds as pde10 inhibitors
RU2561063C1 (ru) *	2014-07-01	2015-08-20	Общество с ограниченной ответственностью "Научно-производственное объединение "Фарматрон" (НПО "Фарматрон")	Способ коррекции неврологических нарушений при хронической алкогольной интоксикации
US10005792B2 (en)	2014-09-03	2018-06-26	Ctxt Pty. Ltd.	Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived PRMT5-inhibitors
GB201415573D0 (en)	2014-09-03	2014-10-15	Cancer Therapeutics Crc Pty Ltd	Compounds
WO2016034673A1 (en)	2014-09-03	2016-03-10	Ctxt Pty Ltd	Tetrahydroisoquinoline derived prmt5-inhibitors
GB201604020D0 (en)	2016-03-09	2016-04-20	Ctxt Pty Ltd	Compounds
GB201604027D0 (en)	2016-03-09	2016-04-20	Ctxt Pty Ltd	Compounds
GB201604031D0 (en)	2016-03-09	2016-04-20	Ctxt Pty Ltd	Compounds
GB201604022D0 (en)	2016-03-09	2016-04-20	Ctxt Pty Ltd	Compounds
GB201604029D0 (en)	2016-03-09	2016-04-20	Ctxt Pty Ltd	Compounds
GB201604030D0 (en)	2016-03-09	2016-04-20	Ctxt Pty Ltd	Compounds
JP7343170B2 (ja) *	2017-05-12	2023-09-12	ボードオブトラスティーズオブザサザンイリノイユニバーシティオンビハーフオブサザンイリノイユニバーシティエドワーズビル	３，４，５－三置換－１，２，４－トリアゾールおよび３，４，５－三置換－３－チオ－１，２，４－トリアゾール、ならびにそれらの使用
US10941153B2 (en) *	2018-05-31	2021-03-09	Regents Of The University Of Minnesota	Substituted phenethylamine derivatives
GB202117129D0 (en) *	2021-11-26	2022-01-12	Epidarex Exeed Ltd	Compounds

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4408049A (en)	1980-09-17	1983-10-04	The Upjohn Company	Substituted piperazinyl-1,2,4-triazoles
US4338453A (en) *	1980-09-17	1982-07-06	The Upjohn Company	Aminoalkyl-1,2,4-triazoles
US4577020A (en) *	1983-01-25	1986-03-18	The Upjohn Company	Aminoalkyl and aminoalkenyl triazoles as anti-psychotic agents
FR2601952B1 (fr) *	1986-07-23	1988-11-25	Carpibem	Nouveaux derives amino alkyl thio de triazolopyridine ou triazoloquinoline, leurs procedes de preparation, medicaments les contenant, utiles notamment comme antalgiques
AU644500B2 (en) *	1990-12-20	1993-12-09	Merrell Dow Pharmaceuticals Inc.	3-aryl-5-alkylthio-4h-1,2,4-triazoles for treatment of hyperreflexia due to spinal trauma
EP0586525B1 (en)	1991-05-20	1997-04-16	PHARMACIA & UPJOHN COMPANY	Carboxamido-(1,2n)-carbocyclic-2-aminotetralin derivatives
AU669866B2 (en)	1991-11-05	1996-06-27	Smithkline Beecham Corporation	Endothelin receptor antagonists
FR2687146B1 (fr)	1992-02-12	1994-04-01	Adir Cie	Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
KR100331667B1 (ko)	1993-04-27	2002-11-08	스미스클라인 비참 코포레이션	엔도텔린수용체길항제
DE4338396A1 (de) *	1993-11-10	1995-05-11	Basf Ag	N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
FR2722194B1 (fr)	1994-07-06	1996-08-23	Adir	Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmacuetiques qui les contiennent
DE4425144A1 (de) *	1994-07-15	1996-01-18	Basf Ag	Triazolverbindungen und deren Verwendung
AU4368996A (en) *	1994-11-23	1996-06-17	Neurogen Corporation	Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands
AU5147196A (en)	1995-03-27	1996-10-16	Smithkline Beecham Plc	Bicyclic amine derivatives and their use as anti-psychotic a gents
AU5272296A (en)	1995-04-06	1996-10-23	Novo Nordisk A/S	Benzopyranopyrrole compounds, their preparation and use
GB9518572D0 (en)	1995-09-12	1995-11-15	Smithkline Beecham Plc	Compounds
JPH11515030A (ja) *	1995-11-10	1999-12-21	ノボノルディスクアクティーゼルスカブ	シス−ベンズ［ｅ］インドール化合物のエナンチオマー、これらの製造、及びドーパミン−Ｄ３受容体選択的医薬としての利用
FR2742149B1 (fr) *	1995-12-11	1998-02-13	Inst Nat Sante Rech Med	Nouveaux derives de 2-naphtamides et leurs applications therapeutiques
DE19600934A1 (de)	1996-01-12	1997-07-17	Basf Ag	Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung
US5688950A (en)	1996-04-23	1997-11-18	Neurogen Corporation	Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands
CA2253927A1 (en)	1996-05-11	1997-11-20	Smithkline Beecham P.L.C.	Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
CA2255612A1 (en) *	1996-05-31	1997-12-04	Pharmacia & Upjohn Company	Aryl substituted cyclic amines as selective dopamine d3 ligands
GB9612153D0 (en)	1996-06-11	1996-08-14	Smithkline Beecham Plc	Compounds
JP2000517301A (ja) *	1996-08-14	2000-12-26	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	テトラヒドロイソキノリン誘導体およびそれらの薬理学的使用
JPH10195056A (ja) *	1996-11-12	1998-07-28	Takeda Chem Ind Ltd	縮合ベンゼン誘導体、その製造法および剤
ES2168682T3 (es)	1996-12-06	2002-06-16	Abbott Lab	Compuestos alfa-1 adrenergicos a base de benzopiranopirrol y de benzopiranopiridina.
FR2760014B1 (fr)	1997-02-27	1999-04-09	Adir	Nouveaux composes de 2-amino indane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB9708694D0 (en)	1997-04-30	1997-06-18	Smithkline Beecham Plc	Compounds
GB9708805D0 (en)	1997-05-01	1997-06-25	Smithkline Beecham Plc	Compounds
BR9809591A (pt) *	1997-05-03	2001-09-11	Smithkline Beecham Plc	Derivados de tetraidoisoquinolina como moduladores de receptores de dopamina d3
GB9709303D0 (en)	1997-05-09	1997-06-25	Smithkline Beecham Plc	Compounds
GB9710366D0 (en) *	1997-05-20	1997-07-16	Biocompatibles Ltd	Stent deployment device
FR2764890B1 (fr)	1997-06-24	1999-08-27	Adir	Nouveaux derives chromeniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE19728996A1 (de)	1997-07-07	1999-01-14	Basf Ag	Triazolverbindungen und deren Verwendung
TWI274750B (en)	1999-01-12	2007-03-01	Abbott Gmbh & Co Kg	Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same

2000
- 2000-01-10 TW TW089100271A patent/TWI274750B/zh not_active IP Right Cessation
- 2000-01-10 AR ARP000100079A patent/AR022229A1/es not_active Application Discontinuation
- 2000-01-10 AR ARP000100080A patent/AR022230A1/es not_active Application Discontinuation
- 2000-01-10 AR ARP000100078A patent/AR022228A1/es not_active Application Discontinuation
- 2000-01-12 EP EP00902583A patent/EP1140908B1/de not_active Expired - Lifetime
- 2000-01-12 ES ES00903574T patent/ES2334326T3/es not_active Expired - Lifetime
- 2000-01-12 CN CNB008049432A patent/CN1267430C/zh not_active Expired - Fee Related
- 2000-01-12 DE DE50015802T patent/DE50015802D1/de not_active Expired - Lifetime
- 2000-01-12 JP JP2000593605A patent/JP4615125B2/ja not_active Expired - Fee Related
- 2000-01-12 TR TR2001/02026T patent/TR200102026T2/xx unknown
- 2000-01-12 AT AT00902583T patent/ATE424398T1/de not_active IP Right Cessation
- 2000-01-12 DE DE50015576T patent/DE50015576D1/de not_active Expired - Lifetime
- 2000-01-12 CN CN00804933A patent/CN1347414A/zh active Pending
- 2000-01-12 US US09/889,161 patent/US6602867B1/en not_active Expired - Lifetime
- 2000-01-12 CA CA002359952A patent/CA2359952A1/en not_active Abandoned
- 2000-01-12 CA CA2359948A patent/CA2359948C/en not_active Expired - Fee Related
- 2000-01-12 HU HU0200522A patent/HUP0200522A3/hu unknown
- 2000-01-12 WO PCT/EP2000/000176 patent/WO2000042037A1/de not_active Ceased
- 2000-01-12 KR KR1020077004587A patent/KR100775720B1/ko not_active Expired - Fee Related
- 2000-01-12 AT AT00901535T patent/ATE366729T1/de not_active IP Right Cessation
- 2000-01-12 JP JP2000593606A patent/JP2002534521A/ja not_active Ceased
- 2000-01-12 EP EP00903574A patent/EP1144405B1/de not_active Expired - Lifetime
- 2000-01-12 ES ES00901535T patent/ES2288839T3/es not_active Expired - Lifetime
- 2000-01-12 CO CO00001265A patent/CO5150182A1/es unknown
- 2000-01-12 AT AT00903574T patent/ATE449768T1/de not_active IP Right Cessation
- 2000-01-12 HU HU0200709A patent/HUP0200709A3/hu unknown
- 2000-01-12 CZ CZ20012551A patent/CZ303926B6/cs not_active IP Right Cessation
- 2000-01-12 CN CNB008049424A patent/CN1149209C/zh not_active Expired - Fee Related
- 2000-01-12 ID IDW00200101733A patent/ID29930A/id unknown
- 2000-01-12 BR BR0007500-0A patent/BR0007500A/pt not_active Application Discontinuation
- 2000-01-12 EP EP00901535A patent/EP1140907B1/de not_active Expired - Lifetime
- 2000-01-12 HR HR20010590A patent/HRP20010590A2/hr not_active Application Discontinuation
- 2000-01-12 CO CO00001268A patent/CO5150227A1/es unknown
- 2000-01-12 WO PCT/EP2000/000177 patent/WO2000042036A1/de not_active Ceased
- 2000-01-12 PL PL349841A patent/PL201889B1/pl unknown
- 2000-01-12 NZ NZ512864A patent/NZ512864A/xx not_active IP Right Cessation
- 2000-01-12 PL PL350246A patent/PL200238B1/pl unknown
- 2000-01-12 SK SK985-2001A patent/SK9852001A3/sk unknown
- 2000-01-12 KR KR1020017008780A patent/KR100730667B1/ko not_active Expired - Fee Related
- 2000-01-12 BR BR0007504-3A patent/BR0007504A/pt not_active Application Discontinuation
- 2000-01-12 KR KR1020017008777A patent/KR100687682B1/ko not_active Expired - Fee Related
- 2000-01-12 JP JP2000593604A patent/JP4933694B2/ja not_active Expired - Fee Related
- 2000-01-12 US US09/889,163 patent/US6583166B1/en not_active Expired - Lifetime
- 2000-01-12 WO PCT/EP2000/000175 patent/WO2000042038A1/de not_active Ceased
- 2000-01-12 AU AU24367/00A patent/AU773047B2/en not_active Ceased
- 2000-01-12 AU AU25412/00A patent/AU772948B2/en not_active Ceased
- 2000-01-12 CO CO00001269A patent/CO5150224A1/es unknown
- 2000-01-12 CZ CZ20012550A patent/CZ20012550A3/cs unknown
- 2000-01-12 DE DE50014472T patent/DE50014472D1/de not_active Expired - Lifetime
- 2000-01-12 CA CA002359942A patent/CA2359942A1/en not_active Abandoned
- 2000-01-12 IL IL14413600A patent/IL144136A0/xx active IP Right Grant
- 2000-01-12 ID IDW00200101681A patent/ID29552A/id unknown
- 2000-01-12 AU AU22897/00A patent/AU2289700A/en not_active Abandoned
- 2000-01-12 US US09/889,156 patent/US6579892B1/en not_active Expired - Lifetime
- 2000-01-12 IL IL14413700A patent/IL144137A0/xx unknown
- 2000-01-12 HK HK02106847.0A patent/HK1045311B/zh not_active IP Right Cessation
- 2000-01-12 NZ NZ512830A patent/NZ512830A/en not_active IP Right Cessation
- 2000-01-12 TR TR2001/02025T patent/TR200102025T2/xx unknown
- 2000-01-12 SK SK986-2001A patent/SK9862001A3/sk unknown
2001
- 2001-07-03 IL IL144136A patent/IL144136A/en not_active IP Right Cessation
- 2001-07-11 NO NO20013444A patent/NO20013444L/no not_active Application Discontinuation
- 2001-07-11 NO NO20013443A patent/NO20013443L/no not_active Application Discontinuation
- 2001-08-03 BG BG105784A patent/BG65086B1/bg unknown
- 2001-08-03 BG BG105783A patent/BG65105B1/bg unknown
- 2001-08-10 ZA ZA200106585A patent/ZA200106585B/en unknown
- 2001-08-10 ZA ZA200106584A patent/ZA200106584B/en unknown

Also Published As

Publication number	Publication date
CN1345318A (zh)	2002-04-17
IL144137A0 (en)	2002-05-23
HUP0200709A3 (en)	2004-07-28
TWI274750B (en)	2007-03-01
AU772948B2 (en)	2004-05-13
BG65086B1 (bg)	2007-02-28
NO20013443L (no)	2001-07-12
PL201889B1 (pl)	2009-05-29
KR100730667B1 (ko)	2007-06-21
NZ512830A (en)	2003-08-29
JP4933694B2 (ja)	2012-05-16
JP2002534520A (ja)	2002-10-15
IL144136A0 (en)	2002-05-23
ZA200106585B (en)	2002-08-12
NO20013443D0 (no)	2001-07-11
ATE424398T1 (de)	2009-03-15
AR022229A1 (es)	2002-09-04
ID29552A (id)	2001-09-06
WO2000042036A1 (de)	2000-07-20
JP2002534521A (ja)	2002-10-15
HK1045311B (zh)	2007-03-30
CO5150224A1 (es)	2002-04-29
HUP0200522A3 (en)	2003-05-28
DE50015576D1 (de)	2009-04-16
CO5150227A1 (es)	2002-04-29
KR20070032830A (ko)	2007-03-22
AU2289700A (en)	2000-08-01
CA2359952A1 (en)	2000-07-20
BR0007500A (pt)	2001-10-23
ATE449768T1 (de)	2009-12-15
CN1347414A (zh)	2002-05-01
AU2436700A (en)	2000-08-01
ATE366729T1 (de)	2007-08-15
BG105783A (en)	2002-03-29
IL144136A (en)	2006-12-10
JP4615125B2 (ja)	2011-01-19
CA2359948A1 (en)	2000-07-20
PL349841A1 (en)	2002-09-23
CA2359948C (en)	2010-09-21
EP1140907B1 (de)	2007-07-11
AU2541200A (en)	2000-08-01
CZ303926B6 (cs)	2013-06-26
EP1144405A1 (de)	2001-10-17
BG105784A (en)	2002-02-28
KR20010086470A (ko)	2001-09-12
SK9862001A3 (en)	2002-04-04
KR100687682B1 (ko)	2007-02-28
CZ20012551A3 (cs)	2002-03-13
PL200238B1 (pl)	2008-12-31
NO20013444L (no)	2001-07-11
CN1149209C (zh)	2004-05-12
DE50014472D1 (de)	2007-08-23
HUP0200522A2 (en)	2002-06-29
AR022230A1 (es)	2002-09-04
AR022228A1 (es)	2002-09-04
BG65105B1 (bg)	2007-02-28
TR200102025T2 (tr)	2002-05-21
ID29930A (id)	2001-10-25
CO5150182A1 (es)	2002-04-29
PL350246A1 (en)	2002-12-02
EP1140907A1 (de)	2001-10-10
US6579892B1 (en)	2003-06-17
HRP20010590A2 (en)	2003-08-31
DE50015802D1 (de)	2010-01-07
BR0007504A (pt)	2001-10-02
ES2334326T3 (es)	2010-03-09
SK9852001A3 (en)	2002-04-04
NZ512864A (en)	2003-04-29
WO2000042038A1 (de)	2000-07-20
KR20010086471A (ko)	2001-09-12
CZ20012550A3 (cs)	2002-02-13
CA2359942A1 (en)	2000-07-20
HUP0200709A2 (hu)	2002-07-29
HK1045311A1 (en)	2002-11-22
EP1140908A1 (de)	2001-10-10
EP1144405B1 (de)	2009-11-25
KR100775720B1 (ko)	2007-11-09
ZA200106584B (en)	2002-08-12
US6602867B1 (en)	2003-08-05
CN1345319A (zh)	2002-04-17
US6583166B1 (en)	2003-06-24
ES2288839T3 (es)	2008-02-01
TR200102026T2 (tr)	2001-12-21
AU773047B2 (en)	2004-05-13
EP1140908B1 (de)	2009-03-04
JP2002534519A (ja)	2002-10-15
CN1267430C (zh)	2006-08-02
WO2000042037A1 (de)	2000-07-20

Publication	Publication Date	Title
NO20013444D0 (no)	2001-07-11	Triazolforbindelser med dopamin-D3-reseptor-affinet
MX9700430A (es)	1998-05-31	El uso de compuestos heterociclicos.
NO970162L (no)	1997-03-14	Substituerte pyrimidinforbindelser og anvendelse derav
DK1200418T3 (da)	2004-07-26	Nematodicide trifluorbutener
AU2002213336A1 (en)	2002-04-29	Substituted heterocyclic compounds for treating multidrug resistance
PT935465E (pt)	2004-08-31	Compostos novos de imidazole substituido
BR9810342A (pt)	2000-09-05	Novos compostos imidazola substituìdos
PT998460E (pt)	2004-07-30	Novos derivados de tetrazole
DE60020595D1 (de)	2005-07-07	3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p38-kinase-inhibitoren
YU1302A (sh)	2005-03-15	Derivati aminotiazola i njihova primena kao liganada crf receptora
ATE281439T1 (de)	2004-11-15	3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p38-kinase-inhibitoren
AP2001002188A0 (en)	2001-06-30	5HT1 antagonists for antidepressant therapy.
ZA200107985B (en)	2002-12-24	Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa.
PT1244614E (pt)	2004-10-29	Inibidores de triptase
ID27733A (id)	2001-04-26	Metoksiminofenilasetamida
MXPA03003478A (es)	2003-07-14	Compuestos heterociclicos 2-sustituidos y su uso para tratar resistencia a multiples farmacos.
TR200003083T2 (tr)	2001-02-21	CNS hastalıklarının tedavisi için paroxetine 10-camphorsulfonate.
SI1358182T1 (en)	2005-02-28	Diazocine derivates and their use as tryptase inhibitors
BG102613A (en)	1999-07-30	New substituted imidazoles
ATE295746T1 (de)	2005-06-15	Radioaktiv beschichtete stents
MX9700125A (es)	1998-01-31	Compuestos de pirimidina.

Legal Events

Date	Code	Title	Description
2004-12-06	FC2A	Withdrawal, rejection or dismissal of laid open patent application