NO20003511L - Lipase-inhiberende polymerer - Google Patents
Lipase-inhiberende polymererInfo
- Publication number
- NO20003511L NO20003511L NO20003511A NO20003511A NO20003511L NO 20003511 L NO20003511 L NO 20003511L NO 20003511 A NO20003511 A NO 20003511A NO 20003511 A NO20003511 A NO 20003511A NO 20003511 L NO20003511 L NO 20003511L
- Authority
- NO
- Norway
- Prior art keywords
- inhibiting polymers
- lipase inhibiting
- polymers
- patient
- methods
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 4
- 102000004882 Lipase Human genes 0.000 title abstract 2
- 108090001060 Lipase Proteins 0.000 title abstract 2
- 239000004367 Lipase Substances 0.000 title abstract 2
- 235000019421 lipase Nutrition 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US537998A | 1998-01-09 | 1998-01-09 | |
| US09/166,510 US6267952B1 (en) | 1998-01-09 | 1998-10-05 | Lipase inhibiting polymers |
| PCT/US1999/000195 WO1999034786A2 (fr) | 1998-01-09 | 1999-01-06 | Polymeres inhibiteurs de lipase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20003511D0 NO20003511D0 (no) | 2000-07-07 |
| NO20003511L true NO20003511L (no) | 2000-09-07 |
Family
ID=26674279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20003511A NO20003511L (no) | 1998-01-09 | 2000-07-07 | Lipase-inhiberende polymerer |
Country Status (20)
| Country | Link |
|---|---|
| US (6) | US6267952B1 (fr) |
| EP (1) | EP1043982B1 (fr) |
| JP (1) | JP2002500182A (fr) |
| KR (1) | KR100620634B1 (fr) |
| CN (2) | CN1287489A (fr) |
| AT (1) | ATE308979T1 (fr) |
| AU (1) | AU747016B2 (fr) |
| BR (1) | BR9907233A (fr) |
| CA (1) | CA2318416A1 (fr) |
| DE (1) | DE69928219T2 (fr) |
| DK (1) | DK1043982T3 (fr) |
| ES (1) | ES2253872T3 (fr) |
| HK (1) | HK1079706A1 (fr) |
| HU (1) | HUP0101128A3 (fr) |
| IL (1) | IL137098A (fr) |
| NO (1) | NO20003511L (fr) |
| NZ (1) | NZ505296A (fr) |
| PL (1) | PL193453B1 (fr) |
| RU (1) | RU2207861C2 (fr) |
| WO (1) | WO1999034786A2 (fr) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6267952B1 (en) * | 1998-01-09 | 2001-07-31 | Geltex Pharmaceuticals, Inc. | Lipase inhibiting polymers |
| PE20010588A1 (es) * | 1999-09-10 | 2001-06-23 | Procter & Gamble | Conjugados polimericos inhibidores de enzimas proteoliticas y lipoliticas |
| ATE476998T1 (de) * | 1999-09-10 | 2010-08-15 | Procter & Gamble | Polyoxyalkylen-konjugate als enzyminhibitoren |
| AR025609A1 (es) | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones lipidas solidas |
| AR025587A1 (es) | 1999-09-13 | 2002-12-04 | Hoffmann La Roche | Formulaciones en dispersion que contienen inhibidores de lipasa |
| EP1132389A1 (fr) | 2000-03-06 | 2001-09-12 | Vernalis Research Limited | Nouveaux dérivés de l'azaindole pour le traitement de l'obésité |
| MXPA02012583A (es) * | 2000-06-27 | 2003-04-10 | Hoffmann La Roche | Metodo para preparacion de una composicion. |
| DE60110232T2 (de) | 2000-07-28 | 2006-01-19 | F. Hoffmann-La Roche Ag | Neue verwendung von lipase-inhibitoren |
| HRP20030029B1 (en) | 2000-07-28 | 2005-06-30 | F. Hoffmann - La Roche Ag | New pharmaceutical composition |
| PT1311260E (pt) | 2000-08-09 | 2008-05-02 | Hoffmann La Roche | Utilização de inibidores de lipase para o tratamento da dispepsia |
| US6900226B2 (en) | 2000-09-06 | 2005-05-31 | Hoffman-La Roche Inc. | Neuropeptide Y antagonists |
| US7473691B2 (en) * | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US6660731B2 (en) * | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US6638926B2 (en) | 2000-09-15 | 2003-10-28 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| AU2002221670B2 (en) | 2000-10-16 | 2006-11-02 | F. Hoffmann-La Roche Ag | Indoline derivatives and their use as 5-HT2 receptor ligands |
| GB0030710D0 (en) | 2000-12-15 | 2001-01-31 | Hoffmann La Roche | Piperazine derivatives |
| CA2432799C (fr) * | 2000-12-21 | 2008-08-19 | Vertex Pharmaceuticals Incorporated | Composes de pyrazole presentant une grande utilite comme inhibiteurs de proteine kinase |
| CA2432085C (fr) | 2000-12-27 | 2009-02-24 | F. Hoffmann-La Roche Ag | Derives d'indole et leur utilisation en tant que ligands de recepteurs 5-ht2b et 5-ht2c |
| GB0106177D0 (en) | 2001-03-13 | 2001-05-02 | Hoffmann La Roche | Piperazine derivatives |
| DE60225274T2 (de) | 2001-05-21 | 2009-03-26 | F. Hoffmann-La Roche Ag | Chinolinderivate als liganden für den neuropeptid-y-rezeptor |
| US20030027786A1 (en) | 2001-06-06 | 2003-02-06 | Karsten Maeder | Lipase inhibiting composition |
| US6787558B2 (en) | 2001-09-28 | 2004-09-07 | Hoffmann-La Roche Inc. | Quinoline derivatives |
| GB0202015D0 (en) | 2002-01-29 | 2002-03-13 | Hoffmann La Roche | Piperazine Derivatives |
| ES2304498T3 (es) | 2002-02-04 | 2008-10-16 | F. Hoffmann-La Roche Ag | Derivados de quinolina como antagonistas de npy. |
| MXPA04007697A (es) * | 2002-02-06 | 2004-11-10 | Vertex Pharma | Compuestos de heteroarilo utiles como inhibidores de gsk-3. |
| ATE512979T1 (de) * | 2002-02-19 | 2011-07-15 | Procter & Gamble | Neue lipase aus pilzen |
| DE60316411T2 (de) | 2002-02-28 | 2008-06-12 | F. Hoffmann-La Roche Ag | Thiazolderivate als npy-rezeptorantagonisten |
| ATE468336T1 (de) * | 2002-03-15 | 2010-06-15 | Vertex Pharma | Azolylaminoazine als proteinkinasehemmer |
| AU2003223930A1 (en) * | 2002-06-14 | 2003-12-31 | Novo Nordisk A/S | Pharmaceutical use of boronic acids and esters thereof |
| MY141867A (en) * | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| WO2004005265A1 (fr) | 2002-07-05 | 2004-01-15 | F. Hoffmann-La Roche Ag | Derives de quinazoline |
| PT1532145E (pt) * | 2002-08-02 | 2007-01-31 | Vertex Pharma | Composiçoes de pirazole úteis como inibidores de gsk-3 |
| BR0313278A (pt) | 2002-08-07 | 2005-07-05 | Hoffmann La Roche | Compostos, processo para a preparação de um composto, composição farmacêutica que compreende o mesmo e sua utilização, método para o tratamento e profilaxia de enfermidades e obesidade e utilização dos compostos |
| EP1578816A1 (fr) * | 2002-11-19 | 2005-09-28 | Genzyme Corporation | Derives polymeres d'acide boronique tenant lieu d'inhibiteurs de la lipase |
| US7601718B2 (en) * | 2003-02-06 | 2009-10-13 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
| GB0314967D0 (en) | 2003-06-26 | 2003-07-30 | Hoffmann La Roche | Piperazine derivatives |
| CN100422179C (zh) | 2003-08-12 | 2008-10-01 | 霍夫曼-拉罗奇有限公司 | 2-氨基-5-苯甲酰基噻唑npy拮抗剂 |
| CA2533464A1 (fr) | 2003-08-12 | 2005-02-17 | F. Hoffmann-La Roche Ag | Derives de thiazole utiles comme antagonistes de npy * |
| US20050239859A2 (en) * | 2003-09-03 | 2005-10-27 | Solvay Pharmaceuticals Gmbh | Novel medical uses of 4,5-dihydro-1h-pyrazole derivatives having cb1- antagonistic activity |
| US20050143441A1 (en) * | 2003-10-27 | 2005-06-30 | Jochen Antel | Novel medical combination treatment of obesity involving 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity |
| US20050124660A1 (en) * | 2003-10-27 | 2005-06-09 | Jochen Antel | Novel medical uses of compounds showing CB1-antagonistic activity and combination treatment involving said compounds |
| US7517890B2 (en) | 2003-11-20 | 2009-04-14 | Children's Hospital Medical Center | GTPase inhibitors and methods of use |
| CA2548172A1 (fr) * | 2003-12-04 | 2005-06-23 | Vertex Pharmaceuticals Incorporated | Quinoxalines utiles comme inhibiteurs des proteines kinases |
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| US7826982B2 (en) | 2005-07-29 | 2010-11-02 | Children's Hospital Medical Center | Method of identifying inhibitors using a 3-D structure of RAC-1 GTPASE |
| EP1945635B1 (fr) | 2005-08-18 | 2009-05-06 | F.Hoffmann-La Roche Ag | Derives de thiazolyle piperidine utile comme modulateurs du recepteur h3 |
| JP2009504771A (ja) * | 2005-08-18 | 2009-02-05 | バーテックス ファーマシューティカルズ インコーポレイテッド | ピラジンキナーゼ阻害剤 |
| AR056499A1 (es) * | 2005-09-06 | 2007-10-10 | Serapis Farmaceuticals Ltd | Compuestos |
| WO2007056163A2 (fr) * | 2005-11-03 | 2007-05-18 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines utiles en tant qu'inhibiteurs de kinases |
| KR101047204B1 (ko) | 2005-11-30 | 2011-07-06 | 에프. 호프만-라 로슈 아게 | H3 조절제로서 사용하기 위한1,1-다이옥소-싸이오모폴린일 인돌일 메탄온 유도체 |
| CN101316840B (zh) | 2005-11-30 | 2012-08-08 | 霍夫曼-拉罗奇有限公司 | 1,5-取代的吲哚-2-基酰胺衍生物 |
| ES2342979T3 (es) | 2005-11-30 | 2010-07-20 | F. Hoffmann-La Roche Ag | Derivados de indol-2-carboxamida sustituidos en 5. |
| DE602006010433D1 (de) | 2005-12-09 | 2009-12-24 | Hoffmann La Roche | Für die behandlung von obesitas geeignete tricyclische amidderivate |
| CN101326187A (zh) | 2005-12-15 | 2008-12-17 | 霍夫曼-拉罗奇有限公司 | 吡咯并[2,3-c]吡啶衍生物 |
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| US7432255B2 (en) | 2006-05-16 | 2008-10-07 | Hoffmann-La Roche Inc. | 1H-indol-5-yl-piperazin-1-yl-methanone derivatives |
| BRPI0711740A2 (pt) | 2006-05-30 | 2011-12-06 | Hoffmann La Roche | compostos, processo para a sua manufatura,composições farmacêuticas que os compreendem, método para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, método para o tratamento ou prevenção de obesidade, de diabetes do tipo ii, e uso dos compostos na manufatura de medicamentos |
| US7514433B2 (en) | 2006-08-03 | 2009-04-07 | Hoffmann-La Roche Inc. | 1H-indole-6-yl-piperazin-1-yl-methanone derivatives |
| DE602007004750D1 (de) * | 2006-11-02 | 2010-03-25 | Vertex Pharma | Als inhibitoren von proteinkinasen geeignete aminopyridine und aminopyrimidine |
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| WO2008077086A1 (fr) * | 2006-12-19 | 2008-06-26 | Vertex Pharmaceuticals Incorporated | Aminopyridines utiles comme inhibiteurs de protéine kinases |
| EP2134709A1 (fr) | 2007-03-09 | 2009-12-23 | Vertex Pharmaceuticals, Inc. | Utilisation des aminopyridines comme inhibiteurs de protéines kinases |
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| NZ580343A (en) | 2007-04-13 | 2012-03-30 | Vertex Pharma | Aminopyrimidines useful as kinase inhibitors |
| JP5389785B2 (ja) * | 2007-05-02 | 2014-01-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | キナーゼ阻害剤として有用なチアゾールおよびピラゾール |
| CA2688584A1 (fr) * | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines servant d'inhibiteurs de kinases |
| CA2694381A1 (fr) * | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines servant d'inhibiteurs de kinases |
| AU2008257044A1 (en) * | 2007-05-24 | 2008-12-04 | Vertex Pharmaceuticals Incorporated | Thiazoles and pyrazoles useful as kinase inhibitors |
| EP2183237A1 (fr) | 2007-07-25 | 2010-05-12 | F. Hoffmann-Roche AG | Dérivés d'amide d'acide benzofurane- et benzo[b]thiophène-2-carboxylique et leur utilisation comme modulateurs du récepteur h3 de l'histamine |
| AU2008282156B2 (en) * | 2007-07-31 | 2014-07-17 | Vertex Pharmaceuticals Incorporated | Process for preparing 5-fluoro-1H-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof |
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| CN102199172A (zh) * | 2010-03-24 | 2011-09-28 | 金凯美(大连)医药科技有限公司 | 一种1-取代亚磷酰二氯的制备方法 |
| WO2013166043A1 (fr) | 2012-05-02 | 2013-11-07 | Children's Hospital Medical Center | Rajeunissement de cellules précurseurs |
| US10028503B2 (en) | 2014-06-18 | 2018-07-24 | Children's Hospital Medical Center | Platelet storage methods and compositions for same |
| US20220288197A1 (en) | 2019-08-16 | 2022-09-15 | Children’s Hospital Medicai Center | Methods of treating a subject with a cdc42-specific inhibitor |
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| US5993675A (en) * | 1997-12-31 | 1999-11-30 | Hagerthy; Albert P. | Fuel-water separator for marine and diesel engines |
| AU740233B2 (en) * | 1998-01-09 | 2001-11-01 | Genzyme Corporation | Fat-binding polymers |
| US6267952B1 (en) * | 1998-01-09 | 2001-07-31 | Geltex Pharmaceuticals, Inc. | Lipase inhibiting polymers |
| US6299868B1 (en) * | 1999-07-14 | 2001-10-09 | Geltex Pharmaceuticals, Inc. | Fat-binding polymers |
| US5942500A (en) * | 1998-04-27 | 1999-08-24 | Perry; Stephen C. | Dietary composition to reduce dietary fats |
-
1998
- 1998-10-05 US US09/166,510 patent/US6267952B1/en not_active Expired - Fee Related
-
1999
- 1999-01-06 US US09/226,585 patent/US6352692B1/en not_active Expired - Fee Related
- 1999-01-06 PL PL99344022A patent/PL193453B1/pl not_active IP Right Cessation
- 1999-01-06 HU HU0101128A patent/HUP0101128A3/hu unknown
- 1999-01-06 EP EP99901332A patent/EP1043982B1/fr not_active Expired - Lifetime
- 1999-01-06 ES ES99901332T patent/ES2253872T3/es not_active Expired - Lifetime
- 1999-01-06 NZ NZ505296A patent/NZ505296A/xx unknown
- 1999-01-06 AU AU21056/99A patent/AU747016B2/en not_active Ceased
- 1999-01-06 KR KR1020007007607A patent/KR100620634B1/ko not_active Expired - Fee Related
- 1999-01-06 CA CA002318416A patent/CA2318416A1/fr not_active Abandoned
- 1999-01-06 BR BR9907233-5A patent/BR9907233A/pt not_active Application Discontinuation
- 1999-01-06 RU RU2000120917/14A patent/RU2207861C2/ru not_active IP Right Cessation
- 1999-01-06 CN CN99802023A patent/CN1287489A/zh active Pending
- 1999-01-06 DK DK99901332T patent/DK1043982T3/da active
- 1999-01-06 CN CNA2004100879814A patent/CN1636574A/zh active Pending
- 1999-01-06 WO PCT/US1999/000195 patent/WO1999034786A2/fr not_active Ceased
- 1999-01-06 DE DE69928219T patent/DE69928219T2/de not_active Expired - Fee Related
- 1999-01-06 AT AT99901332T patent/ATE308979T1/de not_active IP Right Cessation
- 1999-01-06 JP JP2000527237A patent/JP2002500182A/ja active Pending
- 1999-01-06 IL IL137098A patent/IL137098A/en active IP Right Grant
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2000
- 2000-07-07 NO NO20003511A patent/NO20003511L/no not_active Application Discontinuation
- 2000-11-16 US US09/714,541 patent/US6558657B1/en not_active Expired - Fee Related
- 2000-11-16 US US09/714,327 patent/US6572850B1/en not_active Expired - Fee Related
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2003
- 2003-02-05 US US10/359,458 patent/US6875428B2/en not_active Expired - Fee Related
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2004
- 2004-10-07 US US10/960,579 patent/US20050085535A1/en not_active Abandoned
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2005
- 2005-12-29 HK HK05112104.3A patent/HK1079706A1/zh unknown
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