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NO20000995L - Optisk rene camptotecin analoger, optisk rent mellomprodukt, fremgangsmÕte for fremstilling av disse - Google Patents

Optisk rene camptotecin analoger, optisk rent mellomprodukt, fremgangsmÕte for fremstilling av disse

Info

Publication number
NO20000995L
NO20000995L NO20000995A NO20000995A NO20000995L NO 20000995 L NO20000995 L NO 20000995L NO 20000995 A NO20000995 A NO 20000995A NO 20000995 A NO20000995 A NO 20000995A NO 20000995 L NO20000995 L NO 20000995L
Authority
NO
Norway
Prior art keywords
optically pure
camptotecin
analogs
preparation
pure intermediate
Prior art date
Application number
NO20000995A
Other languages
English (en)
Other versions
NO324882B1 (no
NO20000995D0 (no
Inventor
Jean-Bernard Cazaux
Olivier Lavergne
Christine Le Breton
Eric Manginot
Dennis Bigg
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of NO20000995L publication Critical patent/NO20000995L/no
Publication of NO20000995D0 publication Critical patent/NO20000995D0/no
Publication of NO324882B1 publication Critical patent/NO324882B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
NO20000995A 1997-08-29 2000-02-28 Optisk rene camptotecin analoger, optisk rent mellomprodukt, fremgangsmate for fremstilling av disse, anvendelse og farmasoytisk preparat NO324882B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9710785A FR2768431B1 (fr) 1997-08-29 1997-08-29 Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
PCT/FR1998/001768 WO1999011646A1 (fr) 1997-08-29 1998-08-07 Analogues optiquement purs de la camptothecine, intermediaire de synthese optiquement pur et son procede de preparation

Publications (3)

Publication Number Publication Date
NO20000995L true NO20000995L (no) 2000-02-28
NO20000995D0 NO20000995D0 (no) 2000-02-28
NO324882B1 NO324882B1 (no) 2007-12-27

Family

ID=9510590

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20000995A NO324882B1 (no) 1997-08-29 2000-02-28 Optisk rene camptotecin analoger, optisk rent mellomprodukt, fremgangsmate for fremstilling av disse, anvendelse og farmasoytisk preparat

Country Status (25)

Country Link
EP (2) EP1378512A1 (no)
JP (1) JP2001514261A (no)
KR (1) KR100570254B1 (no)
CN (3) CN1104434C (no)
AR (1) AR016856A1 (no)
AT (1) ATE253069T1 (no)
AU (1) AU760863B2 (no)
BR (1) BR9811405A (no)
CA (1) CA2301739C (no)
CZ (1) CZ297896B6 (no)
DE (1) DE69819340T2 (no)
DK (1) DK1007527T3 (no)
ES (1) ES2209196T3 (no)
FR (1) FR2768431B1 (no)
HR (1) HRP20000110A2 (no)
HU (1) HUP0003429A3 (no)
IL (2) IL134437A0 (no)
NO (1) NO324882B1 (no)
NZ (1) NZ502862A (no)
PL (1) PL195289B1 (no)
PT (1) PT1007527E (no)
RU (1) RU2233283C2 (no)
TW (1) TW419479B (no)
WO (1) WO1999011646A1 (no)
ZA (1) ZA987445B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790261B1 (fr) 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
CA2580747A1 (en) * 2004-09-21 2006-03-30 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R .A.S.) Novel processes for the production of useful intermediates
CN100465175C (zh) * 2005-11-29 2009-03-04 中国人民解放军第二军医大学 7-位取代高喜树碱类化合物及作为药物的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
US5459269A (en) * 1992-06-18 1995-10-17 North Carolina State University 14-halo-camptothecins
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
JP3576171B2 (ja) * 1995-06-21 2004-10-13 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・（エス．セー．エール．アー．エス） カンプトテシンの新規な同族体、その製造方法、その医薬としての用途及びこれを含有する医薬組成物

Also Published As

Publication number Publication date
EP1378512A1 (fr) 2004-01-07
CN1195758C (zh) 2005-04-06
CN1440973A (zh) 2003-09-10
KR100570254B1 (ko) 2006-04-12
ATE253069T1 (de) 2003-11-15
CA2301739A1 (fr) 1999-03-11
AU8989698A (en) 1999-03-22
NO324882B1 (no) 2007-12-27
DE69819340T2 (de) 2004-08-19
EP1007527B1 (fr) 2003-10-29
RU2233283C2 (ru) 2004-07-27
WO1999011646A1 (fr) 1999-03-11
TW419479B (en) 2001-01-21
NZ502862A (en) 2002-10-25
HK1058665A1 (en) 2004-05-28
CZ297896B6 (cs) 2007-04-25
AU760863B2 (en) 2003-05-22
CZ2000711A3 (cs) 2000-08-16
CN1104434C (zh) 2003-04-02
CA2301739C (fr) 2009-11-17
HK1031732A1 (en) 2001-06-22
ZA987445B (en) 1999-02-17
HUP0003429A3 (en) 2002-11-28
PT1007527E (pt) 2004-03-31
FR2768431B1 (fr) 2000-03-24
FR2768431A1 (fr) 1999-03-19
HUP0003429A1 (hu) 2001-07-30
DK1007527T3 (da) 2004-03-08
BR9811405A (pt) 2000-08-29
PL338835A1 (en) 2000-11-20
AR016856A1 (es) 2001-08-01
PL195289B1 (pl) 2007-08-31
JP2001514261A (ja) 2001-09-11
IL134437A (en) 2006-08-01
ES2209196T3 (es) 2004-06-16
HRP20000110A2 (en) 2001-02-28
EP1007527A1 (fr) 2000-06-14
CN1440972A (zh) 2003-09-10
CN1268948A (zh) 2000-10-04
KR20010023394A (ko) 2001-03-26
IL134437A0 (en) 2001-04-30
DE69819340D1 (de) 2003-12-04
NO20000995D0 (no) 2000-02-28

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