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NO179949C - Analogifremgangsmåte for fremstilling av medisinsk virksomme 1-karboksyalkylkinoksalin-2,3 (1H,4H) -dionforbindelser og farmasöytisk godtagbare salter derav - Google Patents

Analogifremgangsmåte for fremstilling av medisinsk virksomme 1-karboksyalkylkinoksalin-2,3 (1H,4H) -dionforbindelser og farmasöytisk godtagbare salter derav

Info

Publication number
NO179949C
NO179949C NO923586A NO923586A NO179949C NO 179949 C NO179949 C NO 179949C NO 923586 A NO923586 A NO 923586A NO 923586 A NO923586 A NO 923586A NO 179949 C NO179949 C NO 179949C
Authority
NO
Norway
Prior art keywords
carboxyalkylquinoxaline
preparation
pharmaceutically acceptable
acceptable salts
dione compounds
Prior art date
Application number
NO923586A
Other languages
English (en)
Other versions
NO923586D0 (no
NO179949B (no
NO923586L (no
Inventor
Anker Steen Joergensen
Carsten Enggaard Stidsen
Peter Faarup
Frederik Christian Groenvald
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO923586D0 publication Critical patent/NO923586D0/no
Publication of NO923586L publication Critical patent/NO923586L/no
Publication of NO179949B publication Critical patent/NO179949B/no
Publication of NO179949C publication Critical patent/NO179949C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO923586A 1990-03-16 1992-09-15 Analogifremgangsmåte for fremstilling av medisinsk virksomme 1-karboksyalkylkinoksalin-2,3 (1H,4H) -dionforbindelser og farmasöytisk godtagbare salter derav NO179949C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK069790A DK69790D0 (da) 1990-03-16 1990-03-16 Heterocykliske forbindelser, deres fremstilling af anvendelse
PCT/DK1991/000078 WO1991013878A1 (en) 1990-03-16 1991-03-15 Quinoxaline compounds and their preparation and use

Publications (4)

Publication Number Publication Date
NO923586D0 NO923586D0 (no) 1992-09-15
NO923586L NO923586L (no) 1992-09-15
NO179949B NO179949B (no) 1996-10-07
NO179949C true NO179949C (no) 1997-01-15

Family

ID=8096500

Family Applications (1)

Application Number Title Priority Date Filing Date
NO923586A NO179949C (no) 1990-03-16 1992-09-15 Analogifremgangsmåte for fremstilling av medisinsk virksomme 1-karboksyalkylkinoksalin-2,3 (1H,4H) -dionforbindelser og farmasöytisk godtagbare salter derav

Country Status (20)

Country Link
US (1) US5166155A (no)
EP (1) EP0520024B1 (no)
JP (1) JPH05505810A (no)
AT (1) ATE139530T1 (no)
AU (1) AU652560B2 (no)
CA (1) CA2078429A1 (no)
CS (1) CS68791A3 (no)
DE (1) DE69120400T2 (no)
DK (2) DK69790D0 (no)
ES (1) ES2089204T3 (no)
FI (1) FI924118A0 (no)
GR (1) GR3020560T3 (no)
HU (1) HUT62274A (no)
IE (1) IE910685A1 (no)
IL (1) IL97405A (no)
NO (1) NO179949C (no)
NZ (1) NZ237431A (no)
PT (1) PT97047B (no)
WO (1) WO1991013878A1 (no)
ZA (1) ZA911779B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT101004B (pt) * 1991-10-26 1999-10-29 Schering Ag Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem
US6057304A (en) * 1992-10-26 2000-05-02 Schering Aktiengesellschaft Quinoxaline-phosphonic acid derivatives
WO1994000124A1 (en) * 1992-06-22 1994-01-06 Eckard Weber Glycine receptor antagonists and the use thereof
FR2696466B1 (fr) * 1992-10-02 1994-11-25 Rhone Poulenc Rorer Sa Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant.
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4314592A1 (de) * 1993-04-28 1994-11-03 Schering Ag Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
DE4340045A1 (de) * 1993-11-24 1995-06-01 Basf Ag Neue Chinoxaline und Arzneimittel daraus
EP0743855A1 (en) * 1994-01-03 1996-11-27 Acea Pharmaceuticals, Inc. 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
DE4428152A1 (de) * 1994-06-22 1996-01-04 Basf Ag Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
DE4439492A1 (de) * 1994-10-25 1996-05-02 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
US5559447A (en) * 1994-11-17 1996-09-24 Cypress Semiconductor Output buffer with variable output impedance
DE19519979A1 (de) * 1995-05-24 1996-11-28 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
DE19521058A1 (de) * 1995-06-09 1996-12-12 Basf Ag Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
DE19545251A1 (de) * 1995-11-24 1997-05-28 Schering Ag Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
GB9604400D0 (en) 1996-03-01 1996-05-01 Pfizer Ltd Compounds useful in therapy
DE19624808A1 (de) 1996-06-21 1998-01-02 Basf Ag Pyrrolylchinoxalindione, ihre Herstellung und Verwendung
NZ334891A (en) * 1996-10-24 2001-04-27 Novartis Ag Substituted aminoalkane phosphonic acids for treating block excitatory amino acid receptors related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
WO1991013878A1 (en) 1991-09-19
AU652560B2 (en) 1994-09-01
NO923586D0 (no) 1992-09-15
DK0520024T3 (da) 1996-10-14
DE69120400D1 (de) 1996-07-25
GR3020560T3 (en) 1996-10-31
AU7576791A (en) 1991-10-10
ZA911779B (en) 1991-12-24
CA2078429A1 (en) 1991-09-17
US5166155A (en) 1992-11-24
FI924118L (fi) 1992-09-15
IE910685A1 (en) 1991-09-25
DE69120400T2 (de) 1996-12-19
EP0520024B1 (en) 1996-06-19
CS68791A3 (en) 1992-02-19
HUT62274A (en) 1993-04-28
IL97405A (en) 1995-12-08
ES2089204T3 (es) 1996-10-01
IL97405A0 (en) 1992-06-21
FI924118A7 (fi) 1992-09-15
FI924118A0 (fi) 1992-09-15
DK69790D0 (da) 1990-03-16
ATE139530T1 (de) 1996-07-15
HU9202953D0 (en) 1992-12-28
NO179949B (no) 1996-10-07
NO923586L (no) 1992-09-15
NZ237431A (en) 1993-09-27
PT97047A (pt) 1991-10-31
PT97047B (pt) 1998-07-31
EP0520024A1 (en) 1992-12-30
JPH05505810A (ja) 1993-08-26

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