[go: up one dir, main page]

NL2018190B1 - Psilocybin or psilocin in combination with cannabinoid - Google Patents

Psilocybin or psilocin in combination with cannabinoid Download PDF

Info

Publication number
NL2018190B1
NL2018190B1 NL2018190A NL2018190A NL2018190B1 NL 2018190 B1 NL2018190 B1 NL 2018190B1 NL 2018190 A NL2018190 A NL 2018190A NL 2018190 A NL2018190 A NL 2018190A NL 2018190 B1 NL2018190 B1 NL 2018190B1
Authority
NL
Netherlands
Prior art keywords
cannabinoid
psilocybin
psilocin
treatment
disorder
Prior art date
Application number
NL2018190A
Other languages
English (en)
Dutch (nl)
Inventor
Küçüksen Murat
Neset Küçüksen Ali
Original Assignee
Procare Beheer B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procare Beheer B V filed Critical Procare Beheer B V
Priority to NL2018190A priority Critical patent/NL2018190B1/en
Priority to DK18710925.1T priority patent/DK3570830T3/da
Priority to US16/478,283 priority patent/US10729706B2/en
Priority to EP18710925.1A priority patent/EP3570830B1/fr
Priority to CA3050679A priority patent/CA3050679C/fr
Priority to ES18710925T priority patent/ES2884949T3/es
Priority to PCT/NL2018/050037 priority patent/WO2018135943A1/fr
Priority to HRP20211105TT priority patent/HRP20211105T1/hr
Priority to SI201830320T priority patent/SI3570830T1/sl
Application granted granted Critical
Publication of NL2018190B1 publication Critical patent/NL2018190B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
NL2018190A 2017-01-18 2017-01-18 Psilocybin or psilocin in combination with cannabinoid NL2018190B1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
NL2018190A NL2018190B1 (en) 2017-01-18 2017-01-18 Psilocybin or psilocin in combination with cannabinoid
DK18710925.1T DK3570830T3 (da) 2017-01-18 2018-01-18 Psilocybin og/eller psilocin i kombination med cannabinoider og/eller terpener
US16/478,283 US10729706B2 (en) 2017-01-18 2018-01-18 Psilocybin and/or psilocin in combination with cannabinoids and/or terpenes
EP18710925.1A EP3570830B1 (fr) 2017-01-18 2018-01-18 Psilocybine et/ou psilocine en combinaison avec des cannabinoïdes et/ou des terpènes
CA3050679A CA3050679C (fr) 2017-01-18 2018-01-18 Psilocybine et/ou psilocine en combinaison avec des cannabinoides et/ou des terpenes
ES18710925T ES2884949T3 (es) 2017-01-18 2018-01-18 Psilocibina y/o psilocina en combinación con cannabinoides y/o terpenos
PCT/NL2018/050037 WO2018135943A1 (fr) 2017-01-18 2018-01-18 Psilocybine et/ou psilocine en combinaison avec des cannabinoïdes et/ou des terpènes
HRP20211105TT HRP20211105T1 (hr) 2017-01-18 2018-01-18 Psilocibin i/ili psilocin u kombinaciji s kanabinoidima i/ili terpenima
SI201830320T SI3570830T1 (sl) 2017-01-18 2018-01-18 Psilocibin in/ali psilocin v kombinaciji s kanabinoidi in/ali terpeni

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL2018190A NL2018190B1 (en) 2017-01-18 2017-01-18 Psilocybin or psilocin in combination with cannabinoid

Publications (1)

Publication Number Publication Date
NL2018190B1 true NL2018190B1 (en) 2018-07-26

Family

ID=61627147

Family Applications (1)

Application Number Title Priority Date Filing Date
NL2018190A NL2018190B1 (en) 2017-01-18 2017-01-18 Psilocybin or psilocin in combination with cannabinoid

Country Status (9)

Country Link
US (1) US10729706B2 (fr)
EP (1) EP3570830B1 (fr)
CA (1) CA3050679C (fr)
DK (1) DK3570830T3 (fr)
ES (1) ES2884949T3 (fr)
HR (1) HRP20211105T1 (fr)
NL (1) NL2018190B1 (fr)
SI (1) SI3570830T1 (fr)
WO (1) WO2018135943A1 (fr)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019016489A2 (pt) * 2017-02-09 2020-04-07 Caamtech Llc composições e métodos compreendendo um derivado da psilocibina
US11974984B2 (en) 2017-02-09 2024-05-07 Caamtech, Inc. Compositions and methods comprising a combination of serotonergic drugs
US12414936B2 (en) 2017-02-09 2025-09-16 Caamtech, Inc. Compositions comprising a serotonergic tryptamine compound
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
EP3713568A1 (fr) 2017-10-26 2020-09-30 Consejo Superior de Investigaciones Cientificas (CSIC) Produit d'association pour le traitement de troubles neurologiques et/ou psychiatriques
WO2019099745A1 (fr) * 2017-11-16 2019-05-23 CaaMTech, LLC Compositions comprenant un dérivé de psilocybine et un cannabinoïde
WO2019246532A1 (fr) * 2018-06-21 2019-12-26 Robert John Petcavich Procédé d'induction de la genèse dendritique et synaptique dans des maladies neurodégénératives chroniques
WO2020181194A1 (fr) * 2019-03-07 2020-09-10 University Of Padova Compositions et méthodes d'utilisation comprenant des substances ayant des actions de plasticité neurale administrées à des doses et formulations non psychédéliques/psychotomimétiques
CN113993522A (zh) 2019-04-17 2022-01-28 指南针探路者有限公司 用赛洛西宾治疗焦虑障碍、头痛病症和进食障碍的方法
DE102019117739A1 (de) 2019-07-01 2021-01-07 Felix Blei Arylalkyamin-, Pyrrol-, Indol- und Opiatderivatkonzentrationsbestimmungsverfahren sowie Testkit unter Verwendung dieses Verfahrens
WO2021003467A1 (fr) * 2019-07-04 2021-01-07 Sw Holdings, Inc. Compositions de dosage et procédés d'utilisation de composés psychédéliques
WO2021016710A1 (fr) * 2019-07-30 2021-02-04 Tassili Life Sciences, Corp. Formulations à libération contrôlée de multiples agents pharmaceutiques actifs, et agents dérivés de psilocybe combinés avec des agents dérivés du cannabis et leurs procédés d'utilisation
CA3147679A1 (fr) * 2019-08-13 2021-02-18 Scott Thompson Methodes de traitement de troubles psychologiques et cerebraux
AU2020358720A1 (en) 2019-10-01 2022-04-21 Empyrean Neuroscience, Inc. Genetic engineering of fungi to modulate tryptamine expression
US12409131B2 (en) 2019-10-03 2025-09-09 Pike Therapeutics Usa, Inc. Transdermal delivery of dronabinol
CA3156257A1 (fr) 2019-10-03 2021-04-08 Starton Therapeutics, Inc. Administration transdermique de dronabinol
US12016829B2 (en) 2019-10-11 2024-06-25 Pike Therapeutics Inc. Pharmaceutical composition and method for treating seizure disorders
AU2020361741B2 (en) 2019-10-11 2024-09-05 Pike Therapeutics Inc. Transdermal compositions comprising cannabidiol (CBD) for use in the treatment of seizure disorders
US12268699B2 (en) 2019-10-14 2025-04-08 Pike Therapeutics Inc. Transdermal delivery of tetrahydrocannabinol
US12121617B2 (en) 2019-10-14 2024-10-22 Pike Therapeutics Inc. Transdermal delivery of cannabidiol
CN114555068A (zh) 2019-10-14 2022-05-27 长矛治疗股份有限公司1219014 B.C.有限公司 大麻二酚的透皮给药
WO2021072530A1 (fr) * 2019-10-15 2021-04-22 Tassili Life Sciences, Corp. Formulations à libération contrôlée d'agents dérivés de psilocybes et leur procédé d'utilisation, et procédés et compositions pour traiter une lésion cérébrale traumatique légère avec un syndrome de stress post-traumatique
IL292404A (en) * 2019-10-21 2022-06-01 Esolate Ltd Compositions including thin compounds and their production
AU2020386445A1 (en) 2019-11-19 2022-06-02 Paul Edward Stamets Tryptamine compositions for enhancing neurite outgrowth
BR112022017097A2 (pt) * 2020-02-28 2022-11-16 Univ Basel Composição e uso da composição
US11801278B2 (en) * 2020-03-05 2023-10-31 Cure Pharmaceutical, Inc. Method for obtaining an extract of a plant biomass
CA3169783A1 (fr) 2020-03-19 2021-09-23 Andrew R. Chadeayne Derives cristallins de psilacetine
US20240277736A1 (en) * 2020-04-17 2024-08-22 Revive Therapeutics Ltd Use of psilocybin in the treatment of neurological brain injury and migraines
US20210346338A1 (en) * 2020-05-07 2021-11-11 Trinidad Consulting, Llc Cannabinoid pouches
PH12022553135A1 (en) 2020-05-19 2024-03-04 Cybin Irl Ltd Deuterated tryptamine derivatives and methods of use
WO2021234608A1 (fr) * 2020-05-19 2021-11-25 Cybin Irl Limited Dérivés de tryptamine deutérés et procédés d'utilisation
MX2022016533A (es) 2020-06-17 2023-04-05 Psilo Scientific Ltd Composiciones que comprenden compuestos psicoactivos de organismos psicoactivos.
US12233355B2 (en) 2020-06-17 2025-02-25 Psilo Scientific Ltd. Methanol-based extraction of psychoactive alkaloids from fungus
US20230277568A1 (en) * 2020-07-10 2023-09-07 Eleusis Therapeutics Us, Inc. Method of treatment for psilocybin or psilocin infusion
WO2022018709A1 (fr) * 2020-07-21 2022-01-27 Ai Pharmaceuticals Jamaica Limited Compositions et méthodes de traitement de psychoses et de troubles psychotiques
US20230405028A1 (en) * 2020-10-12 2023-12-21 Goodcap Pharmaceuticals Ltd. Compositions for reducing inflammation to improve or maintain mental or physical health
WO2022082058A1 (fr) * 2020-10-16 2022-04-21 Eleusis Therapeutics Us, Inc. Méthode de traitement par alcaloïdes tryptamines
WO2022094719A1 (fr) * 2020-11-06 2022-05-12 Pacific Myco Biosciences Ltd. Procédé de traitement de la dépression par modulation immunitaire
CA3113240C (fr) 2020-12-28 2023-09-05 Psilo Scientific Ltd. Composition d'alcaloide psychoactif transmucosal et preparation connexe
US11312684B1 (en) 2021-02-10 2022-04-26 Eleusis Therapeutics Us, Inc. Pharmaceutically acceptable salts of psilocin and uses thereof
AU2022218986A1 (en) * 2021-02-10 2023-09-21 Eleusis Therapeutics Us, Inc. Pharmaceutically acceptable salts of psilocin and uses thereof
US20220273628A1 (en) * 2021-02-19 2022-09-01 Universitätsspital Basel Effects of lysergic acid diethylamide (lsd) and of lsd analogs to assist psychotherapy for generalized anxiety disorder or other anxiety not related to life-threatening illness
WO2022187973A1 (fr) * 2021-03-12 2022-09-15 Allied Corp. Schémas posologiques de compositions pharmaceutiques et nutraceutiques de champignon et de cannabis et leur utilisation pour traiter des troubles du système nerveux central et améliorer la santé mentale
TW202304423A (zh) * 2021-04-01 2023-02-01 美商泰仁生物科學公司 與致幻劑及血清素受體調節劑相關之方法及組合物
WO2022235531A1 (fr) * 2021-05-04 2022-11-10 Mind Medicine, Inc. Troubles du mouvement
US20240261419A1 (en) * 2021-05-10 2024-08-08 London Pharmaceuticals And Research Corporation Psilocybin and psilocin conjugates for treatment of mental illnesses
CA3219041A1 (fr) 2021-05-24 2022-12-01 Canna-Chemistries Llc Sels cristallins de psilocine
CN117642383A (zh) * 2021-05-24 2024-03-01 卡纳-化学有限责任公司 二甲-4-羟色胺的结晶盐
CA3224112A1 (fr) * 2021-06-24 2022-12-29 David Feifel Traitement medicamenteux psychedelique de troubles neuropsychiatriques et de paralysie cerebrale
US20240366638A1 (en) * 2021-06-25 2024-11-07 Synaptive Therapeutics Llc Psilocybin analogs for treating psychological disorders
TW202317545A (zh) 2021-07-07 2023-05-01 美商泰仁生物科學公司 N,n-二甲基色胺及相關致幻劑及其用途
CA3237988A1 (fr) 2021-11-12 2023-05-19 Terran Biosciences Inc. Psilocybine et o-acetylpsilocine, leurs sels et formes a l'etat solide
WO2023130078A2 (fr) 2021-12-31 2023-07-06 Empyrean Neuroscience, Inc. Mycélium génétiquement modifié pour la production d'alcaloïdes psychotropes
EP4486448A1 (fr) 2022-03-04 2025-01-08 Reset Pharmaceuticals, Inc. Co-cristaux ou sels comprenant de la psilocine
WO2023215342A1 (fr) * 2022-05-03 2023-11-09 Wesana Health Inc. Compositions et procédés de traitement de la névralgie du trijumeau
WO2023215344A2 (fr) * 2022-05-03 2023-11-09 Wesana Health Inc. Compositions et procédés de traitement du syndrome cluster-tic
WO2023215338A1 (fr) * 2022-05-03 2023-11-09 Wesana Health Inc. Compositions et procédés de traitement de l'algie vasculaire de la face
GB202214721D0 (en) * 2022-10-06 2022-11-23 Rewire Therapeutics Ltd A treatment for mental disorders
WO2024098160A1 (fr) * 2022-11-10 2024-05-16 Allen Greenspoon Formulation administrable par voie orale
AU2024220413A1 (en) * 2023-02-17 2025-09-25 Native Code Bio, Llc Therapeutic combinations for inflammatory conditions and disorders
WO2024238035A1 (fr) * 2023-05-16 2024-11-21 Mind Medicine, Inc. Troubles du mouvement

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2383700A (en) 2001-09-27 2003-07-02 Inquam Frequency converter for CDMA systems
GB0222077D0 (en) 2002-09-23 2002-10-30 Gw Pharma Ltd Methods of preparing cannabinoids from plant material
GB2438682A (en) 2006-06-01 2007-12-05 Gw Pharma Ltd New use for cannabinoids
WO2009043395A2 (fr) 2007-10-05 2009-04-09 Sti Pharmaceuticals Ltd. Composition pharmaceutique
CA2968703A1 (fr) 2015-05-19 2016-11-24 Joseph Robert Knight Procede d'isolation d'alcaloides et d'acides amines, et compositions contenant des alcaloides et des acides amines isoles

Also Published As

Publication number Publication date
CA3050679C (fr) 2024-04-23
CA3050679A1 (fr) 2018-07-26
SI3570830T1 (sl) 2021-11-30
HRP20211105T1 (hr) 2021-10-15
EP3570830A1 (fr) 2019-11-27
DK3570830T3 (da) 2021-07-12
EP3570830B1 (fr) 2021-04-21
WO2018135943A1 (fr) 2018-07-26
US10729706B2 (en) 2020-08-04
US20190350949A1 (en) 2019-11-21
ES2884949T3 (es) 2021-12-13

Similar Documents

Publication Publication Date Title
NL2018190B1 (en) Psilocybin or psilocin in combination with cannabinoid
US20220226257A1 (en) Use of cannabinoids in the treatment of comorbidities associated with epilepsy
US9017737B2 (en) Use of cannabinoids in combination with an anti-psychotic medicament
US10653641B2 (en) Use of cannabinoids in the treatment of mental disorders
KR20220147636A (ko) 칸나비디올 및 에버롤리무스에 의한 복합 결절성 경화증 치료 방법
KR20200094756A (ko) 간질의 치료에서 칸나비노이드의 용도
RS60767B1 (sr) Upotreba kanabinoida u lečenju atoničnih napada kod lenoks-gastoovog sindroma
Chkonia et al. Patients with functional psychoses show similar visual backward masking deficits
Reznik et al. Cannabidiol: a potential treatment for post Ebola syndrome?
HK40017964A (en) Psilocybin and/or psilocin in combination with cannabinoids and/or terpenes
HK40017964B (en) Psilocybin and/or psilocin in combination with cannabinoids and/or terpenes
US20230000793A1 (en) Treatment of 22q11.2 deletion syndrome with cannabidiol
US11253519B2 (en) Composition used to improve symptoms of autism spectrum disorder, and method using same for improving symptoms of autism spectrum disorder
Kocak et al. Autophagy–NAD+ axis: Emerging insights into neuronal homeostasis and neurodegenerative diseases
CN120417909A (zh) 格列齐特的新用途
RU2660583C1 (ru) Применение буспирона для лечения функционального головокружения
Vgenopoulou et al. Melatonin levels in Alzheimer disease
Ahmed et al. Severe depression and behavioral disturbance, an unusual presentation of intracerebral hemorrhage in a 78-year-old man
HK1186416A (en) Use of cannabinoids in combination with aripiprazole