NL2000337A1 - Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum. - Google Patents

Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum. Download PDF

Info

Publication number: NL2000337A1
Authority: NL; Netherlands
Prior art keywords: pyrrole; isopropyl; amino; pyrimidine; methoxyphenyl
Prior art date: 2005-12-09

Application number

NL2000337A

Other languages

English (en)

Dutch (nl)

Inventor

Tracy Lee Boyden

Feng Guo

Susan Deborah Lagreca

Douglas Alan Lorenz

Ravi Mysore Shanker

Franzanne Vreeland

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-09

Filing date

2006-11-27

Publication date

2007-06-12

2006-11-27 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2007-06-12 Publication of NL2000337A1 publication Critical patent/NL2000337A1/nl

Links

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239000000230 xanthan gum Substances 0.000 description 1
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239000000811 xylitol Substances 0.000 description 1
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ZPUHVPYXSITYDI-HEUWMMRCSA-N xyotax Chemical compound OC(=O)[C@@H](N)CCC(O)=O.O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 ZPUHVPYXSITYDI-HEUWMMRCSA-N 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NL2000337A 2005-12-09 2006-11-27 Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum. NL2000337A1 (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US74907005P	2005-12-09	2005-12-09
US74907005		2005-12-09

Publications (1)

Publication Number	Publication Date
NL2000337A1 true NL2000337A1 (nl)	2007-06-12

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Application Number	Title	Priority Date	Filing Date
NL2000337A NL2000337A1 (nl)	2005-12-09	2006-11-27	Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum.

Country Status (8)

Country	Link
AR (1)	AR058293A1 (fr)
DO (1)	DOP2006000271A (fr)
GT (1)	GT200600496A (fr)
NL (1)	NL2000337A1 (fr)
PE (1)	PE20071037A1 (fr)
TW (1)	TW200733965A (fr)
UY (1)	UY29991A1 (fr)
WO (1)	WO2007066189A2 (fr)

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WO2014026125A1 (fr)	2012-08-10	2014-02-13	Incyte Corporation	Dérivés de pyrazine en tant qu'inhibiteurs de fgfr
SG11201502331RA (en)	2012-09-26	2015-04-29	Univ California	Modulation of ire1
US9266892B2 (en)	2012-12-19	2016-02-23	Incyte Holdings Corporation	Fused pyrazoles as FGFR inhibitors
WO2014172644A2 (fr)	2013-04-19	2014-10-23	Incyte Corporation	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr
US10851105B2 (en)	2014-10-22	2020-12-01	Incyte Corporation	Bicyclic heterocycles as FGFR4 inhibitors
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UA121669C2 (uk)	2015-02-20	2020-07-10	Інсайт Корпорейшн	Біциклічні гетероцикли як інгібітори fgfr
MA41551A (fr)	2015-02-20	2017-12-26	Incyte Corp	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
CN107722012B (zh) *	2016-08-11	2020-05-29	斯福瑞（南通）制药有限公司	制备4-氯-7H-吡咯并[2,3-d]嘧啶的方法
AR111960A1 (es)	2017-05-26	2019-09-04	Incyte Corp	Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
SI3788047T1 (sl)	2018-05-04	2024-11-29	Incyte Corporation	Trdne oblike inhibitorja fgfr in postopki priprave le-teh
CN112566912A (zh)	2018-05-04	2021-03-26	因赛特公司	Fgfr抑制剂的盐
WO2020185532A1 (fr)	2019-03-08	2020-09-17	Incyte Corporation	Méthodes de traitement du cancer au moyen d'un inhibiteur de fgfr
US11591329B2 (en)	2019-07-09	2023-02-28	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
US12122767B2 (en)	2019-10-01	2024-10-22	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
EP4045151A1 (fr)	2019-10-14	2022-08-24	Incyte Corporation	Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr
US11566028B2 (en)	2019-10-16	2023-01-31	Incyte Corporation	Bicyclic heterocycles as FGFR inhibitors
CA3163875A1 (fr)	2019-12-04	2021-06-10	Incyte Corporation	Heterocycles tricycliques en tant qu'inhibiteurs de fgfr
EP4069695A1 (fr)	2019-12-04	2022-10-12	Incyte Corporation	Dérivés d'un inhibiteur de fgfr
WO2021146424A1 (fr)	2020-01-15	2021-07-22	Incyte Corporation	Hétérocycles bicycliques en tant qu'inhibiteurs de fgfr
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WO2022261160A1 (fr)	2021-06-09	2022-12-15	Incyte Corporation	Hétérocycles tricycliques en tant qu'inhibiteurs de fgfr
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2006
- 2006-11-24 WO PCT/IB2006/003416 patent/WO2007066189A2/fr not_active Ceased
- 2006-11-27 NL NL2000337A patent/NL2000337A1/nl active Search and Examination
- 2006-12-05 DO DO2006000271A patent/DOP2006000271A/es unknown
- 2006-12-06 UY UY29991A patent/UY29991A1/es not_active Application Discontinuation
- 2006-12-06 PE PE2006001565A patent/PE20071037A1/es not_active Application Discontinuation
- 2006-12-07 GT GT200600496A patent/GT200600496A/es unknown
- 2006-12-07 AR ARP060105422A patent/AR058293A1/es unknown
- 2006-12-08 TW TW095145947A patent/TW200733965A/zh unknown

Also Published As

Publication number	Publication date
WO2007066189A2 (fr)	2007-06-14
GT200600496A (es)	2007-07-17
TW200733965A (en)	2007-09-16
DOP2006000271A (es)	2007-08-15
AR058293A1 (es)	2008-01-30
WO2007066189A3 (fr)	2008-08-14
PE20071037A1 (es)	2007-11-19
UY29991A1 (es)	2007-07-31

Publication	Publication Date	Title
NL2000337A1 (nl)	2007-06-12	Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum.
CN115297861B (zh)	2024-07-12	化合物及其用途
TWI546293B (zh)	2016-08-21	芳基與雜芳基稠合內醯胺
CA3220160A1 (fr)	2022-12-08	Polytherapie comprenant un inhibiteur de mat2a et un inhibiteur de prmt de type ii
DE60111358T2 (de)	2006-05-11	3-(pyrolyllacton)-2-indolinon verbindungen zur verwendung als kinase-hemmstoffe
CN106467541B (zh)	2019-04-05	取代喹诺酮类衍生物或其药学上可接受的盐或立体异构体及其药用组合物和应用
US20080274192A1 (en)	2008-11-06	Pharmaceutical Compositions Comprising an Amorphous Form of a Vegf-R-Inhibitor
TWI334353B (en)	2010-12-11	4-methylpyridopyrimidinone compounds
US20050272755A1 (en)	2005-12-08	Method for treating abnormal cell growth
CN110914267B (zh)	2022-07-12	嘧啶并吡啶酮或者吡啶并吡啶酮类化合物及其应用
TW201734013A (zh)	2017-10-01	Egfr酪胺酸激酶之臨床重要突變體之選擇性抑制劑
AU2005286190A1 (en)	2006-03-30	Therapeutic combinations comprising poly(ADP-ribose) polymerases inhibitor
CN104540831B (zh)	2017-11-07	用于治疗癌症、自身免疫性炎症和cns紊乱的二氟二氧戊环‑氨基‑苯并咪唑激酶抑制剂
TW202003513A (zh)	2020-01-16	血漿激肽釋放素抑制劑及其用途
WO2016184434A1 (fr)	2016-11-24	Composé pyrido-azahétérocyclique, et procédé de préparation et utilisation correspondants
TW200911781A (en)	2009-03-16	Novel crystalline forms of a VEGF-R inhibitor
CN109790122A (zh)	2019-05-21	杂环化合物
US20070287719A1 (en)	2007-12-13	Salts, Prodrugs and Formulations of 1-[5-(4-Amino-7-Isopropyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonyl)-2-Methoxy-Phenyl]-3-(2,4-Dichloro-Phenyl)-Urea
CN110650961B (zh)	2022-09-27	Parp抑制剂、其药物组合物、制备方法和应用
KR20090116789A (ko)	2009-11-11	암을 치료하기 위한 ｈｓｐ-90 억제제로서의 2-아미노-5,7-다이하이드로-6ｈ-피롤로[3,4-ｄ]피리미딘 유도체
EP4359082A1 (fr)	2024-05-01	Inhibiteurs de mutation her2
CA3021185C (fr)	2024-06-04	Compose heterocyclique condense
RU2476434C2 (ru)	2013-02-27	Кристаллическая форма 1 2-((r)-2-метилпирролидин-2-ил)-1н-бензимидазол-4-карбоксамида
WO2018187294A1 (fr)	2018-10-11	Combinaisons de composés de pyrimido-pyridazinone, procédés, kits et formulations associées
AU2013318672A1 (en)	2015-03-19	Means and method for treating solid tumours

Legal Events

Date	Code	Title	Description
2007-08-01	AD1A	A request for search or an international type search has been filed