NL1003283C2 - Modificatie van een polypeptide voor het vergroten van de elektro- transport-flux en toepassing daarvan als geneesmiddel. - Google Patents

Modificatie van een polypeptide voor het vergroten van de elektro- transport-flux en toepassing daarvan als geneesmiddel. Download PDF

Info

Publication number: NL1003283C2
Authority: NL; Netherlands
Prior art keywords: analog; polypeptide; gin; electrotransport; ala
Prior art date: 1995-06-06

Application number

NL1003283A

Other languages

English (en)

Dutch (nl)

Other versions

NL1003283A1 (nl

Inventor

Allen Holladay Leslie

Original Assignee

Alza Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-06

Filing date

1996-06-06

Publication date

1997-05-02

1996-06-06 Application filed by Alza Corp filed Critical Alza Corp

1996-12-09 Publication of NL1003283A1 publication Critical patent/NL1003283A1/xx

1997-05-02 Application granted granted Critical

1997-05-02 Publication of NL1003283C2 publication Critical patent/NL1003283C2/nl

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis

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Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Cosmetics (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Electrotherapy Devices (AREA)

NL1003283A 1995-06-06 1996-06-06 Modificatie van een polypeptide voor het vergroten van de elektro- transport-flux en toepassing daarvan als geneesmiddel. NL1003283C2 (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US46661095A	1995-06-06	1995-06-06
US46661095		1995-06-06

Publications (2)

Publication Number	Publication Date
NL1003283A1 NL1003283A1 (nl)	1996-12-09
NL1003283C2 true NL1003283C2 (nl)	1997-05-02

Family

ID=23852435

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL1003283A NL1003283C2 (nl)	1995-06-06	1996-06-06	Modificatie van een polypeptide voor het vergroten van de elektro- transport-flux en toepassing daarvan als geneesmiddel.

Country Status (12)

Country	Link
US (2)	US7324846B2 (fr)
JP (2)	JP4354529B2 (fr)
AU (1)	AU6590396A (fr)
BE (1)	BE1009704A3 (fr)
BR (1)	BR9609149A (fr)
CA (1)	CA2220146A1 (fr)
DE (1)	DE19681439T1 (fr)
FR (1)	FR2735132B1 (fr)
GB (1)	GB2317179B (fr)
IT (1)	IT1285405B1 (fr)
NL (1)	NL1003283C2 (fr)
WO (1)	WO1996039422A2 (fr)

Families Citing this family (14)

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IT1285405B1 (it) *	1995-06-06	1998-06-03	Alza Corp	Modificazione di farmaci polipeptidici per accrescere il flusso per elettrotrasporto.
DE60031709T2 (de)	1999-10-14	2007-06-28	Pola Chemical Industries, Inc.	Zusammensetzungen für die elektroporation
JP4799803B2 (ja) *	2000-09-08	2011-10-26	マサチューセッツインスティテュートオブテクノロジー	Ｇ−ｃｓｆアナログ組成物および方法
US7497855B2 (en)	2002-09-04	2009-03-03	Microchips, Inc.	Method and device for the controlled delivery of parathyroid hormone
WO2004027064A2 (fr) *	2002-09-18	2004-04-01	Centre Hospitalier De L'universite De Montreal (Chum)	Analogues de ghrh
CA2595457A1 (fr)	2005-01-25	2006-08-03	Microchips, Inc.	Regulation de la liberation de medicament par la modification transitoire de microenvironnements locaux
PE20130557A1 (es)	2010-03-04	2013-05-19	Pfenex Inc	Metodo para producir proteinas de interferon recombinantes solubles sin desnaturalizacion
EP2552949B1 (fr)	2010-04-01	2016-08-17	Pfenex Inc.	Procédés pour la production de g-csf dans une cellule hôte de pseudomonas
AU2012345768B2 (en)	2011-11-30	2016-05-12	Kindeva Drug Delivery L.P.	Microneedle device having a peptide therapeutic agent and an amino acid, methods of making and using the same
PT3122426T (pt)	2014-03-28	2023-02-28	Univ Duke	Tratamento de cancro da mama utilizando moduladores seletivos do recetor de estrogénio
EP3288383A4 (fr)	2015-04-29	2019-01-23	Radius Pharmaceuticals, Inc.	Méthodes de traitement du cancer
ES2981967T3 (es)	2017-01-05	2024-10-14	Radius Pharmaceuticals Inc	Formas polimórficas de RAD1901-2HCl
JP7473486B2 (ja)	2018-07-04	2024-04-23	ラジウスファーマシューティカルズ，インコーポレイテッド	Ｒａｄ１９０１－２ｈｃｌの多形形態
JOP20210218A1 (ar)	2019-02-12	2023-01-30	Radius Pharmaceuticals Inc	عمليات ومركبات

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US4628043A (en) *	1983-04-26	1986-12-09	The Salk Institute For Biological Studies	Hypothalamic GRF agonists
WO1993025197A1 (fr) *	1992-06-12	1993-12-23	Affymax Technologies N.V.	Compositions et procedes destines a ameliorer la liberation et l'acheminement de medicaments
EP0643981A1 (fr) *	1993-09-22	1995-03-22	Takeda Chemical Industries, Ltd.	Electrode concrétée pour iontophorèse
WO1995011988A1 (fr) *	1993-10-25	1995-05-04	Affymax Technologies N.V.	Composes a activite de parathormone et vecteurs d'adn recombine les codant
EP0667355A1 (fr) *	1994-02-10	1995-08-16	Hoechst Aktiengesellschaft	Dérivé de l'hirudine et leur méthode de fabrication

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US5250022A (en)	1990-09-25	1993-10-05	Rutgers, The State University Of New Jersey	Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose
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EP0429842B1 (fr)	1989-10-27	1996-08-28	Korea Research Institute Of Chemical Technology	Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
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DK10191D0 (da)	1991-01-22	1991-01-22	Novo Nordisk As	Hidtil ukendte peptider
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IT1285405B1 (it) *	1995-06-06	1998-06-03	Alza Corp	Modificazione di farmaci polipeptidici per accrescere il flusso per elettrotrasporto.

1996
- 1996-06-05 IT IT96TO000496A patent/IT1285405B1/it active IP Right Grant
- 1996-06-06 DE DE19681439T patent/DE19681439T1/de not_active Withdrawn
- 1996-06-06 WO PCT/US1996/009377 patent/WO1996039422A2/fr not_active Ceased
- 1996-06-06 AU AU65903/96A patent/AU6590396A/en not_active Abandoned
- 1996-06-06 JP JP50171097A patent/JP4354529B2/ja not_active Expired - Fee Related
- 1996-06-06 NL NL1003283A patent/NL1003283C2/nl not_active IP Right Cessation
- 1996-06-06 FR FR9607002A patent/FR2735132B1/fr not_active Expired - Fee Related
- 1996-06-06 BE BE9600517A patent/BE1009704A3/fr not_active IP Right Cessation
- 1996-06-06 BR BR9609149A patent/BR9609149A/pt not_active Application Discontinuation
- 1996-06-06 GB GB9725981A patent/GB2317179B/en not_active Expired - Fee Related
- 1996-06-06 CA CA002220146A patent/CA2220146A1/fr not_active Abandoned
2001
- 2001-12-10 US US10/016,403 patent/US7324846B2/en not_active Expired - Fee Related
2007
- 2007-11-27 US US11/945,536 patent/US20090275877A1/en not_active Abandoned
2008
- 2008-12-12 JP JP2008316824A patent/JP2009149639A/ja not_active Abandoned

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4628043A (en) *	1983-04-26	1986-12-09	The Salk Institute For Biological Studies	Hypothalamic GRF agonists
WO1993025197A1 (fr) *	1992-06-12	1993-12-23	Affymax Technologies N.V.	Compositions et procedes destines a ameliorer la liberation et l'acheminement de medicaments
EP0643981A1 (fr) *	1993-09-22	1995-03-22	Takeda Chemical Industries, Ltd.	Electrode concrétée pour iontophorèse
WO1995011988A1 (fr) *	1993-10-25	1995-05-04	Affymax Technologies N.V.	Composes a activite de parathormone et vecteurs d'adn recombine les codant
EP0667355A1 (fr) *	1994-02-10	1995-08-16	Hoechst Aktiengesellschaft	Dérivé de l'hirudine et leur méthode de fabrication

Also Published As

Publication number	Publication date
JPH11507341A (ja)	1999-06-29
BE1009704A3 (fr)	1997-07-01
GB2317179B (en)	1999-07-28
FR2735132A1 (fr)	1996-12-13
US7324846B2 (en)	2008-01-29
US20020107505A1 (en)	2002-08-08
IT1285405B1 (it)	1998-06-03
WO1996039422A3 (fr)	1997-03-06
GB9725981D0 (en)	1998-02-04
WO1996039422A2 (fr)	1996-12-12
ITTO960496A0 (it)	1996-06-05
FR2735132B1 (fr)	1998-04-24
JP2009149639A (ja)	2009-07-09
IE960413A1 (en)	1996-12-11
DE19681439T1 (de)	1998-07-23
AU6590396A (en)	1996-12-24
ITTO960496A1 (it)	1997-12-05
BR9609149A (pt)	1999-02-23
GB2317179A (en)	1998-03-18
JP4354529B2 (ja)	2009-10-28
US20090275877A1 (en)	2009-11-05
CA2220146A1 (fr)	1996-12-12
NL1003283A1 (nl)	1996-12-09

Publication	Publication Date	Title
US20090275877A1 (en)	2009-11-05	Method of Enhancing Electrotransport Polypeptide Flux By Amino Acid Substitution with Histidine
CA2087087C (fr)	2000-07-18	Molecules pour administration par ionophorese
JP2008500345A (ja)	2008-01-10	増加された安定度をもつ生体分子含有調製物
Foldvari et al.	1998	Palmitoyl derivatives of interferon α: potential for cutaneous delivery
WO1995011988A1 (fr)	1995-05-04	Composes a activite de parathormone et vecteurs d'adn recombine les codant
KR19980703038A (ko)	1998-09-05	친유성 펩티드 호르몬 유도체
NL1003284C2 (nl)	1997-03-20	Werkwijze voor het vergroten van de elektrotransport-flux van polypeptiden.
JPH10509072A (ja)	1998-09-08	電気的移送式作用剤投与を強化するための組成物と方法
EP4262745B1 (fr)	2025-01-29	Composition pharmaceutique d'agonistes doubles de glp-1/glp-2
JP3737832B2 (ja)	2006-01-25	イオントフォレシス用マトリックス
US5843015A (en)	1998-12-01	Molecules for iontophoretic delivery
IE83528B1 (en)	2004-07-14	Modification of polypeptide drugs to increase electrotransport flux
JP3638316B2 (ja)	2005-04-13	イオントフォレシス用マトリックス
CN1960746A (zh)	2007-05-09	稳定性提高的含生物分子配方
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Frokjaer et al.	2004	12 Formulation, Stability, and Characterization of Protein and Peptide Drugs
WO1997024157A9 (fr)	1997-09-25	Molecules a administrer par iontophorese
WO1997024157A1 (fr)	1997-07-10	Molecules a administrer par iontophorese
HK40095698A (en)	2024-02-02	Pharmaceutical composition of glp-1/glp-2 dual agonists
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장주명	2017	Enhanced drug delivery systems using pH-responsive peptides and reverse electrodialysis
Morishita et al.	2016	Modifying the Physicochemical Nature of Biodrugs by Reversible Lipidization

Legal Events

Date	Code	Title	Description
1997-02-03	AD1A	A request for search or an international type search has been filed
1997-07-01	PD2B	A search report has been drawn up
2012-01-11	V1	Lapsed because of non-payment of the annual fee	Effective date: 20120101