MY196025A - Novel T Cell Receptors and Immune Therapy Using the Same - Google Patents
Novel T Cell Receptors and Immune Therapy Using the SameInfo
- Publication number
- MY196025A MY196025A MYPI2019003103A MYPI2019003103A MY196025A MY 196025 A MY196025 A MY 196025A MY PI2019003103 A MYPI2019003103 A MY PI2019003103A MY PI2019003103 A MYPI2019003103 A MY PI2019003103A MY 196025 A MY196025 A MY 196025A
- Authority
- MY
- Malaysia
- Prior art keywords
- taa
- antigen recognizing
- recognizing constructs
- novel
- tcr
- Prior art date
Links
- 108091008874 T cell receptors Proteins 0.000 title abstract 4
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 title abstract 4
- 238000009169 immunotherapy Methods 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 102100025178 DDB1- and CUL4-associated factor 4-like protein 2 Human genes 0.000 abstract 2
- 101000721255 Homo sapiens DDB1- and CUL4-associated factor 4-like protein 2 Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to antigen recognizing constructs against a tumor associated antigen (TAA) derived from the target protein DDB1 and CUL4 associated factor 4-like 2 (DCAF4L2). The invention in particular provides novel T cell receptor (TCR) based molecules which are selective and specific for the TAA of the invention. The TCR of the invention, and TAA binding fragments derived therefrom, are of use for the diagnosis, treatment and prevention of TAA expressing cancerous diseases. Further provided are nucleic acids encoding the antigen recognizing constructs of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen recognizing constructs and pharmaceutical compositions comprising the compounds of the invention.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662431580P | 2016-12-08 | 2016-12-08 | |
| DE102016123859.7A DE102016123859B3 (en) | 2016-12-08 | 2016-12-08 | New T cell receptors and their use in immunotherapy |
| PCT/EP2017/081893 WO2018104478A1 (en) | 2016-12-08 | 2017-12-07 | Novel t cell receptors and immune therapy using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY196025A true MY196025A (en) | 2023-03-07 |
Family
ID=67874111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2019003103A MY196025A (en) | 2016-12-08 | 2017-12-07 | Novel T Cell Receptors and Immune Therapy Using the Same |
Country Status (6)
| Country | Link |
|---|---|
| CL (1) | CL2019001537A1 (en) |
| CO (1) | CO2019006926A2 (en) |
| IL (1) | IL267131A (en) |
| MY (1) | MY196025A (en) |
| NZ (1) | NZ754366A (en) |
| PH (1) | PH12019501263A1 (en) |
-
2017
- 2017-12-07 MY MYPI2019003103A patent/MY196025A/en unknown
- 2017-12-07 NZ NZ754366A patent/NZ754366A/en not_active IP Right Cessation
-
2019
- 2019-06-05 CL CL2019001537A patent/CL2019001537A1/en unknown
- 2019-06-05 IL IL267131A patent/IL267131A/en unknown
- 2019-06-06 PH PH12019501263A patent/PH12019501263A1/en unknown
- 2019-06-27 CO CONC2019/0006926A patent/CO2019006926A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO2019006926A2 (en) | 2019-09-18 |
| IL267131A (en) | 2019-08-29 |
| NZ754366A (en) | 2022-02-25 |
| PH12019501263A1 (en) | 2020-01-20 |
| CL2019001537A1 (en) | 2019-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12019501241A1 (en) | Novel t cell receptors and immune therapy using the same | |
| PH12020550600A1 (en) | Novel engineered t cell receptors and immune therapy using the same | |
| CA3045233A1 (en) | Novel t cell receptors and immune therapy using the same | |
| MX2023003463A (en) | T cell receptors and immune therapy using the same against prame positive cancers. | |
| WO2018172533A3 (en) | T cell receptors and immune therapy using the same against prame positive cancers | |
| PH12019500312A1 (en) | T cell receptors and immune therapy using the same | |
| PH12019502847A1 (en) | Novel t cell receptors and immune therapy using the same | |
| CR20190276A (en) | NEW T-CELL RECEPTORS AND IMMUNE THERAPY THAT USES THEM | |
| MX395287B (en) | NEW T LYMPHOCYTE RECEPTORS AND IMMUNOTHERAPY BASED ON THEIR USE. | |
| MX2020001996A (en) | Anti-cd137 molecules and use thereof. | |
| JOP20200313A1 (en) | Dll3-cd3 bispecific antibodies | |
| PH12019500122A1 (en) | Bispecific antibody-like binding proteins specifically binding to cd3 and cd123 | |
| MX2019006045A (en) | Psma targeting trispecific proteins and methods of use. | |
| MX2018010824A (en) | Inducible binding proteins and methods of use. | |
| EA202191027A3 (en) | NEW PEPTIDES AND COMBINATIONS OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF SEVERAL TYPES OF TUMORS | |
| PH12019500571A1 (en) | Anti-pd-1 antibodies | |
| EP4279086A3 (en) | Compositions and methods for treating cancer with anti-cd19 immunotherapy | |
| PH12019501263A1 (en) | Novel t cell receptors and immune therapy using the same | |
| MY195101A (en) | Novel T Cell Receptors and Immune Therapy Using the Same | |
| EA202090712A1 (en) | NEW GENETIC ENGINEERED T-CELL RECEPTORS AND IMMUNE THERAPY WITH THEIR USE | |
| EA201991139A1 (en) | NEW T-CELL RECEPTORS AND IMMUNOTHERAPY WITH THEIR APPLICATION | |
| EA201992002A1 (en) | T-CELL RECEPTORS AND IMMUNE THERAPY OF PRAME-POSITIVE CANCER DISEASES WITH THEIR APPLICATION | |
| AR110682A1 (en) | T-CELL RECEIVERS AND IMMUNE THERAPY USING THEM | |
| EA201990488A1 (en) | NEW T-CELL RECEPTORS AND IMMUNOTHERAPY WITH THEIR APPLICATION |