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MXPA06001273A - Compuestos novedosos. - Google Patents

Compuestos novedosos.

Info

Publication number
MXPA06001273A
MXPA06001273A MXPA06001273A MXPA06001273A MXPA06001273A MX PA06001273 A MXPA06001273 A MX PA06001273A MX PA06001273 A MXPA06001273 A MX PA06001273A MX PA06001273 A MXPA06001273 A MX PA06001273A MX PA06001273 A MXPA06001273 A MX PA06001273A
Authority
MX
Mexico
Prior art keywords
ring
optionally substituted
fused heterobicyclic
group
unsaturated
Prior art date
Application number
MXPA06001273A
Other languages
English (en)
Inventor
Kiichiro Ueta
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of MXPA06001273A publication Critical patent/MXPA06001273A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Un compuesto de la formula (I): (ver formula (I)) en donde el Anillo A y el Anillo B son, (1) el Anillo A es un anillo monociclico, heterociclico no saturado, sustituido opcionalmente, y el Anillo B es un anillo monociclico, heterociclico no saturado, sustituido opcionalmente, un anillo heterobiciclico fusionado no saturado, sustituido opcionalmente, o un anillo de benceno sustituido opcionalmente, (2) el Anillo A es un anillo de benceno sustituido opcionalmente, y el Anillo B es un anillo monociclico, heterociclico no saturado, sustituido opcionalmente, un anillo heterobiciclico fusionado no saturado, sustituido opcionalmente, o un anillo de benceno sustituido opcionalmente, o (3) el Anillo A es un anillo heterobiciclico fusionado no saturado, sustituido opcionalmente, en donde el grupo -NR- y el grupo -CH2- estan ambos en el mismo anillo del anillo heterobiciclico no saturado fusionado, y el Anillo B es un anillo monociclico, heterociclico no saturado, sustituido opcionalmente, un anillo heterobiciclico fusionado no saturado, sustituido opcionalmente, o un anillo de benceno sustituido opcionalmente; y R es un atomo de hidrogeno, un grupo alquilo inferior, un grupo alcanoilo inferior o un grupo alcoxicarbonilo inferior, o una sal farmaceuticamente aceptable del mismo, o un profarmaco del mismo.
MXPA06001273A 2003-08-01 2004-07-30 Compuestos novedosos. MXPA06001273A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49152303P 2003-08-01 2003-08-01
PCT/JP2004/011311 WO2005012321A1 (en) 2003-08-01 2004-07-30 Novel compounds

Publications (1)

Publication Number Publication Date
MXPA06001273A true MXPA06001273A (es) 2006-04-11

Family

ID=34115512

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06001273A MXPA06001273A (es) 2003-08-01 2004-07-30 Compuestos novedosos.

Country Status (18)

Country Link
US (1) US7521430B2 (es)
EP (1) EP1654269B1 (es)
JP (1) JP4717811B2 (es)
KR (1) KR101101500B1 (es)
CN (2) CN102060888A (es)
AU (1) AU2004260760B2 (es)
BR (1) BRPI0413233A (es)
CA (1) CA2534022C (es)
EA (1) EA011025B1 (es)
ES (1) ES2527053T3 (es)
IL (1) IL173051A (es)
MX (1) MXPA06001273A (es)
NO (1) NO333679B1 (es)
NZ (1) NZ545305A (es)
TW (1) TWI377209B (es)
UA (5) UA86042C2 (es)
WO (1) WO2005012321A1 (es)
ZA (2) ZA200601686B (es)

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LT2568988T (lt) 2010-05-11 2016-09-12 Janssen Pharmaceutica, N.V. Farmacinės kompozicijos, apimančios 1-(beta-d-gliukopiranozil)-2-tienilmetilbenzeno darinius kaip sglt inhibitorius
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TWI542596B (zh) * 2011-05-09 2016-07-21 健生藥品公司 （２ｓ,３ｒ,４ｒ,５ｓ,６ｒ）－２－（３－（（５－（４－氟苯基）噻吩－２－基）甲基）－４－甲基苯基）－６－（羥甲基）四氫－２ｈ－哌喃－３,４,５－三醇之ｌ－脯胺酸及檸檬酸共晶體
CN105008379B (zh) * 2013-02-26 2018-06-29 田边三菱制药株式会社 α-卤代四酰基葡萄糖的制造方法
CN103896930B (zh) * 2014-04-02 2016-08-17 安徽联创生物医药股份有限公司 卡格列净半水合物药用晶型的制备方法
WO2015181692A1 (en) * 2014-05-27 2015-12-03 Glenmark Pharmaceuticals Limited Process for preparation of canagliflozin
CN104045673B (zh) * 2014-06-06 2017-01-18 安徽省食品药品检验研究院 双‑三氮唑缀合的假二糖衍生物及其制备方法
CN104478968A (zh) * 2015-01-14 2015-04-01 佛山市赛维斯医药科技有限公司 含噻唑基的o-半乳糖苷衍生物、其制备方法和用途
CN106188022A (zh) * 2015-04-30 2016-12-07 上海医药工业研究院 伊格列净的制备方法
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
PL3716979T3 (pl) 2017-11-30 2025-08-04 Idorsia Pharmaceuticals Ltd Połączenie pochodnej 4-pirymidynosulfamidu z inhibitorem sglt-2 do leczenia chorób związanych w endoteliną
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Also Published As

Publication number Publication date
CN1829728A (zh) 2006-09-06
KR101101500B1 (ko) 2012-01-03
NO333679B1 (no) 2013-08-05
TW200510440A (en) 2005-03-16
CA2534022A1 (en) 2005-02-10
ZA200601686B (en) 2007-05-30
EP1654269B1 (en) 2014-10-15
ZA200603880B (en) 2010-01-27
WO2005012321A1 (en) 2005-02-10
JP4717811B2 (ja) 2011-07-06
UA86042C2 (en) 2009-03-25
EP1654269A1 (en) 2006-05-10
UA87991C2 (en) 2009-09-10
CN102060888A (zh) 2011-05-18
AU2004260760A1 (en) 2005-02-10
UA86599C2 (en) 2009-05-12
IL173051A0 (en) 2006-06-11
ES2527053T3 (es) 2015-01-20
NZ545305A (en) 2008-11-28
EA011025B1 (ru) 2008-12-30
CA2534022C (en) 2012-10-02
AU2004260760B2 (en) 2009-08-13
JP2007518682A (ja) 2007-07-12
NO20060219L (no) 2006-04-28
BRPI0413233A (pt) 2006-10-03
TWI377209B (en) 2012-11-21
US7521430B2 (en) 2009-04-21
UA83377C2 (uk) 2008-07-10
US20070060545A1 (en) 2007-03-15
UA85569C2 (ru) 2009-02-10
KR20060132539A (ko) 2006-12-21
IL173051A (en) 2012-06-28
EA200600348A1 (ru) 2006-08-25

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