MXPA05013324A - Preparacion de aerosol comprendiendo un anexo que incluye una composicion de aerosol conteniendo compuesto macrolido. - Google Patents
Preparacion de aerosol comprendiendo un anexo que incluye una composicion de aerosol conteniendo compuesto macrolido.Info
- Publication number
- MXPA05013324A MXPA05013324A MXPA05013324A MXPA05013324A MXPA05013324A MX PA05013324 A MXPA05013324 A MX PA05013324A MX PA05013324 A MXPA05013324 A MX PA05013324A MX PA05013324 A MXPA05013324 A MX PA05013324A MX PA05013324 A MXPA05013324 A MX PA05013324A
- Authority
- MX
- Mexico
- Prior art keywords
- aerosol
- annex
- aerosol composition
- compound
- active ingredient
- Prior art date
Links
- 239000000443 aerosol Substances 0.000 title abstract 9
- 239000000203 mixture Substances 0.000 title abstract 7
- 150000001875 compounds Chemical class 0.000 title abstract 4
- -1 polyethylene Polymers 0.000 abstract 4
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 3
- 239000012260 resinous material Substances 0.000 abstract 2
- 229920000181 Ethylene propylene rubber Polymers 0.000 abstract 1
- 229930182556 Polyacetal Natural products 0.000 abstract 1
- 239000004952 Polyamide Substances 0.000 abstract 1
- 239000004698 Polyethylene Substances 0.000 abstract 1
- 239000004743 Polypropylene Substances 0.000 abstract 1
- QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 abstract 1
- 229920005549 butyl rubber Polymers 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229920001084 poly(chloroprene) Polymers 0.000 abstract 1
- 229920002647 polyamide Polymers 0.000 abstract 1
- 229920001707 polybutylene terephthalate Polymers 0.000 abstract 1
- 229920000573 polyethylene Polymers 0.000 abstract 1
- 229920006324 polyoxymethylene Polymers 0.000 abstract 1
- 229920001155 polypropylene Polymers 0.000 abstract 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 abstract 1
- 239000004810 polytetrafluoroethylene Substances 0.000 abstract 1
- 229960001967 tacrolimus Drugs 0.000 abstract 1
- QJJXYPPXXYFBGM-SHYZHZOCSA-N tacrolimus Natural products CO[C@H]1C[C@H](CC[C@@H]1O)C=C(C)[C@H]2OC(=O)[C@H]3CCCCN3C(=O)C(=O)[C@@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@@H](C[C@H](C)CC(=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)C)OC QJJXYPPXXYFBGM-SHYZHZOCSA-N 0.000 abstract 1
- 229920002725 thermoplastic elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
- B65D83/141—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant specially adapted for specific contents or propellants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
- B65D83/44—Valves specially adapted for the discharge of contents; Regulating devices
- B65D83/52—Metering valves; Metering devices
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Una preparacion de aerosol comprendiendo un anexo incluyendo una composicion de aerosol conteniendo un compuesto macrolido (por ejemplo, tacrolimo) sirviendo como un ingrediente activo, tiene un problema de que la formulacion de la composicion de aerosol se cambia con el paso del tiempo para reducir la proporcion del ingrediente activo en la composicion de aerosol debido a que el compuesto macrolido como el ingrediente activo se adsorbe parcialmente en una "arandela" de una parte de valvula hecha de material resinoso. En una preparacion de aerosol de la invencion comprendiendo una composicion de aerosol conteniendo un compuesto macrolido y un anexo incluyendo la composicion de aerosol, una parte de valvula del anexo tiene una "arandela" hecha de al menos un material resinoso seleccionado de hule de butilo, hule de etileno-propileno, hule de cloropreno, polietileno, tereftalato de polibutileno, poliacetal, poliamida, politetrafluoroetileno, polipropileno y elastomero termoplastico, resolviendo asi el problema.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003165161 | 2003-06-10 | ||
| PCT/JP2004/008270 WO2004110335A1 (ja) | 2003-06-10 | 2004-06-08 | マクロライド系化合物を含有するエアゾール組成物が封入容器に封入されたエアゾール製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05013324A true MXPA05013324A (es) | 2006-03-09 |
Family
ID=33549204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05013324A MXPA05013324A (es) | 2003-06-10 | 2004-06-08 | Preparacion de aerosol comprendiendo un anexo que incluye una composicion de aerosol conteniendo compuesto macrolido. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060124903A1 (es) |
| EP (1) | EP1632208A4 (es) |
| JP (1) | JP3823212B2 (es) |
| KR (1) | KR20060067922A (es) |
| CN (1) | CN1805725A (es) |
| AR (1) | AR044493A1 (es) |
| AU (1) | AU2004246930A1 (es) |
| BR (1) | BRPI0411385A (es) |
| CA (1) | CA2528841A1 (es) |
| MX (1) | MXPA05013324A (es) |
| RU (1) | RU2005141549A (es) |
| TW (1) | TW200504192A (es) |
| WO (1) | WO2004110335A1 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05013324A (es) | 2003-06-10 | 2006-03-09 | Astellas Pharma Inc | Preparacion de aerosol comprendiendo un anexo que incluye una composicion de aerosol conteniendo compuesto macrolido. |
| CA2536876A1 (en) * | 2003-08-29 | 2005-03-17 | Glaxo Group Limited | Pharmaceutical metered dose inhaler and methods relating thereto |
| KR101274996B1 (ko) * | 2006-12-20 | 2013-06-14 | 재단법인 포항산업과학연구원 | 누름식 펌프장치 |
| EP2182957A4 (en) * | 2007-07-31 | 2012-07-18 | Limerick Biopharma Inc | PHOSPHORYLATED PYRONANALOGES AND CORRESPONDING METHODS |
| WO2009158031A2 (en) * | 2008-06-27 | 2009-12-30 | Limerick Biopharma, Inc. | Methods and compositions for therapeutic treatment |
| DE102009022215B4 (de) * | 2009-05-20 | 2011-06-22 | LINDAL Dispenser GmbH, 23923 | Ventil zur dosierten Abgabe von Flüssigkeiten |
| GB0917817D0 (en) | 2009-10-12 | 2009-11-25 | Biotica Tech Ltd | Novel compounds and methods for their production |
| GB0917816D0 (en) | 2009-10-12 | 2009-11-25 | Biotica Tech Ltd | Novel compounds and methods for their production |
| WO2011163600A2 (en) * | 2010-06-25 | 2011-12-29 | Apt Pharmaceuticals, Inc. | Tacrolimus compositions for aerosol administration |
| FR2971772B1 (fr) * | 2011-02-17 | 2013-03-22 | Valois Sas | Dispositif de distribution de produit fluide. |
| CN103586158B (zh) * | 2013-09-10 | 2016-01-20 | 南京腾亚精工科技有限公司 | 一种多功能喷雾阀 |
| CN103724741A (zh) * | 2013-12-16 | 2014-04-16 | 芜湖万润机械有限责任公司 | 一种复合橡胶密封垫材料及其制备方法 |
| CN104225739A (zh) * | 2014-09-30 | 2014-12-24 | 四川普锐特医药科技有限责任公司 | 一种医用定量吸入气雾剂 |
| GB2535796A (en) * | 2015-02-27 | 2016-08-31 | 3M Innovative Properties Co | Improvements in or relating to metered dose inhalers |
| JP6585356B2 (ja) * | 2015-03-05 | 2019-10-02 | 株式会社ダイゾー | 塗布部材 |
| DE202020000677U1 (de) | 2019-02-27 | 2020-03-20 | Aptar Dortmund Gmbh | Ventil und Abgabevorrichtung |
| JP2023089909A (ja) * | 2021-12-16 | 2023-06-28 | 小池化学株式会社 | 酸素ボンベ |
| WO2024123598A1 (en) * | 2022-12-07 | 2024-06-13 | Kindeva Drug Delivery L.P. | Metered dose inhaler |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0832869B2 (ja) * | 1990-03-19 | 1996-03-29 | 三井東圧化学株式会社 | エアゾール製品缶のガス漏洩防止方法 |
| US5290539A (en) * | 1990-12-21 | 1994-03-01 | Minnesota Mining And Manufacturing Company | Device for delivering an aerosol |
| WO1995002651A1 (en) * | 1993-07-15 | 1995-01-26 | Minnesota Mining And Manufacturing Company | Seals for use in an aerosol delivery device |
| US5474758A (en) * | 1993-07-28 | 1995-12-12 | Minnesota Mining And Manufacturing Company | Seals for use in an aerosol delivery device |
| WO1997010806A1 (en) * | 1995-09-19 | 1997-03-27 | Fujisawa Pharmaceutical Co., Ltd. | Aerosol compositions |
| NZ523693A (en) * | 2000-07-10 | 2004-08-27 | Chiron Corp | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
| ES2656210T3 (es) * | 2000-12-22 | 2018-02-26 | Glaxo Group Limited | Inhalador dosificador para xinafoato de salmeterol |
| MXPA05013324A (es) | 2003-06-10 | 2006-03-09 | Astellas Pharma Inc | Preparacion de aerosol comprendiendo un anexo que incluye una composicion de aerosol conteniendo compuesto macrolido. |
-
2004
- 2004-06-08 MX MXPA05013324A patent/MXPA05013324A/es unknown
- 2004-06-08 BR BRPI0411385-3A patent/BRPI0411385A/pt not_active Application Discontinuation
- 2004-06-08 WO PCT/JP2004/008270 patent/WO2004110335A1/ja not_active Ceased
- 2004-06-08 CA CA002528841A patent/CA2528841A1/en not_active Abandoned
- 2004-06-08 CN CNA200480016442XA patent/CN1805725A/zh active Pending
- 2004-06-08 JP JP2005505042A patent/JP3823212B2/ja not_active Expired - Lifetime
- 2004-06-08 KR KR1020057022993A patent/KR20060067922A/ko not_active Withdrawn
- 2004-06-08 RU RU2005141549/14A patent/RU2005141549A/ru not_active Application Discontinuation
- 2004-06-08 EP EP04745839A patent/EP1632208A4/en not_active Withdrawn
- 2004-06-08 US US10/559,380 patent/US20060124903A1/en not_active Abandoned
- 2004-06-08 AU AU2004246930A patent/AU2004246930A1/en not_active Abandoned
- 2004-06-09 AR ARP040101995A patent/AR044493A1/es unknown
- 2004-06-10 TW TW093116628A patent/TW200504192A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1632208A1 (en) | 2006-03-08 |
| CN1805725A (zh) | 2006-07-19 |
| BRPI0411385A (pt) | 2006-08-29 |
| TW200504192A (en) | 2005-02-01 |
| RU2005141549A (ru) | 2006-06-10 |
| CA2528841A1 (en) | 2004-12-23 |
| EP1632208A4 (en) | 2009-02-25 |
| US20060124903A1 (en) | 2006-06-15 |
| KR20060067922A (ko) | 2006-06-20 |
| AU2004246930A1 (en) | 2004-12-23 |
| WO2004110335A1 (ja) | 2004-12-23 |
| JPWO2004110335A1 (ja) | 2006-07-20 |
| JP3823212B2 (ja) | 2006-09-20 |
| AR044493A1 (es) | 2005-09-14 |
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