MXPA05001355A - Formas nuevas adicionales de moleculas de arn de interferencia. - Google Patents
Formas nuevas adicionales de moleculas de arn de interferencia.Info
- Publication number
- MXPA05001355A MXPA05001355A MXPA05001355A MXPA05001355A MXPA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A
- Authority
- MX
- Mexico
- Prior art keywords
- rna molecules
- interfering rna
- stretch
- further novel
- novel forms
- Prior art date
Links
- 230000002452 interceptive effect Effects 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 230000000295 complement effect Effects 0.000 abstract 1
- 229920002477 rna polymer Polymers 0.000 abstract 1
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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Abstract
La presente invencion esta relacionada con un acido ribonucleico que comprende una estructura de hebra doble en donde la estructura de hebra doble comprende una hebra y una segunda hebra, en donde la primera hebra comprende una primera extension de nucleotidos contiguos y en donde la primera extension es por lo menos parcialmente complementaria a un acido nucleico objetivo, y la segunda hebra comprende una segunda extension de nucleotidos contiguos en donde la segunda extension es por lo menos parcialmente identica al acido nucleico objetivo, y en donde la estructura de hebra doble tiene el extremo embotado.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02017601A EP1389637B1 (en) | 2002-08-05 | 2002-08-05 | Blunt-ended interfering RNA molecules |
| US40254102P | 2002-08-12 | 2002-08-12 | |
| EP03008383 | 2003-04-10 | ||
| PCT/EP2003/008666 WO2004015107A2 (en) | 2002-08-05 | 2003-08-05 | Further novel forms of interfering rna molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05001355A true MXPA05001355A (es) | 2005-09-30 |
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| MXPA05001355A MXPA05001355A (es) | 2002-08-05 | 2003-08-05 | Formas nuevas adicionales de moleculas de arn de interferencia. |
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| EP (6) | EP3222724B1 (es) |
| JP (4) | JP5490655B2 (es) |
| KR (1) | KR101201664B1 (es) |
| CN (1) | CN100543137C (es) |
| AT (1) | ATE350473T2 (es) |
| AU (2) | AU2003260370B2 (es) |
| BR (1) | BRPI0313202A8 (es) |
| CA (1) | CA2494930C (es) |
| CY (4) | CY1106422T1 (es) |
| DE (1) | DE60310944T3 (es) |
| DK (4) | DK2258847T3 (es) |
| ES (1) | ES2280826T5 (es) |
| IL (2) | IL166546A0 (es) |
| MX (1) | MXPA05001355A (es) |
| PT (1) | PT1527176E (es) |
| SI (3) | SI2258847T1 (es) |
| WO (1) | WO2004015107A2 (es) |
| ZA (1) | ZA200500459B (es) |
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