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MXPA03002779A - Derivados de glucopiranosiloxibencilbenceno y composiciones medicinales conteniendo los mismos. - Google Patents

Derivados de glucopiranosiloxibencilbenceno y composiciones medicinales conteniendo los mismos.

Info

Publication number
MXPA03002779A
MXPA03002779A MXPA03002779A MXPA03002779A MXPA03002779A MX PA03002779 A MXPA03002779 A MX PA03002779A MX PA03002779 A MXPA03002779 A MX PA03002779A MX PA03002779 A MXPA03002779 A MX PA03002779A MX PA03002779 A MXPA03002779 A MX PA03002779A
Authority
MX
Mexico
Prior art keywords
lower alkoxy
same
compositions containing
medicinal compositions
glucopyranosyloxybenzylbenzene derivatives
Prior art date
Application number
MXPA03002779A
Other languages
English (en)
Inventor
Hideki Fujikura
Original Assignee
Kissei Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical filed Critical Kissei Pharmaceutical
Publication of MXPA03002779A publication Critical patent/MXPA03002779A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Derivados de glucopiranosiloxibencilbenceno representados por la siguiente formula general (l), los cuales tienen una capacidad de absorcion oral mejorada, ejercen un excelente efecto para inhibir la actividad de SGLT2 humano in vivo y, por lo tanto, son utiles como preventivos o remedios para enfermedades provocadas por hiperglicemia, tales como diabetes, complicacion de diabetes y obesidad, en donde P representa un grupo que constituye un promedicamento; y R representa alquilo inferior, alcoxi inferior, alquiltio inferior, alcoxi inferior alquilo inferior, alcoxi inferior alcoxi inferior o alcoxi inferior alquiltio. (ver formula).
MXPA03002779A 2000-09-29 2001-09-21 Derivados de glucopiranosiloxibencilbenceno y composiciones medicinales conteniendo los mismos. MXPA03002779A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000301523 2000-09-29
PCT/JP2001/008239 WO2002028872A1 (fr) 2000-09-29 2001-09-21 Derives de glucopyranosiloxybenzylbenzene et compositions therapeutiques contenant ces composes

Publications (1)

Publication Number Publication Date
MXPA03002779A true MXPA03002779A (es) 2004-05-04

Family

ID=18783054

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03002779A MXPA03002779A (es) 2000-09-29 2001-09-21 Derivados de glucopiranosiloxibencilbenceno y composiciones medicinales conteniendo los mismos.

Country Status (32)

Country Link
US (2) US6872706B2 (es)
EP (1) EP1329456B1 (es)
JP (1) JP3798375B2 (es)
KR (1) KR100647204B1 (es)
CN (1) CN1293087C (es)
AR (1) AR030816A1 (es)
AT (1) ATE335753T1 (es)
AU (2) AU2001290257B2 (es)
BG (1) BG66015B1 (es)
BR (1) BR0114310A (es)
CA (1) CA2423568C (es)
CY (1) CY1106076T1 (es)
CZ (1) CZ303544B6 (es)
DE (1) DE60122193T2 (es)
DK (1) DK1329456T3 (es)
EA (1) EA005994B1 (es)
ES (1) ES2269456T3 (es)
HU (1) HUP0301178A3 (es)
IL (2) IL155071A0 (es)
MX (1) MXPA03002779A (es)
MY (1) MY129023A (es)
NO (1) NO327182B1 (es)
NZ (1) NZ524917A (es)
PE (1) PE20020476A1 (es)
PL (1) PL205607B1 (es)
PT (1) PT1329456E (es)
SI (1) SI1329456T1 (es)
SK (1) SK287811B6 (es)
TW (1) TWI284641B (es)
UA (1) UA73606C2 (es)
WO (1) WO2002028872A1 (es)
ZA (1) ZA200302283B (es)

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CN1020944C (zh) 1990-01-30 1993-05-26 阿图尔-费希尔股份公司费希尔厂 紧固件
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Also Published As

Publication number Publication date
EP1329456A1 (en) 2003-07-23
WO2002028872A1 (fr) 2002-04-11
SI1329456T1 (sl) 2006-12-31
ATE335753T1 (de) 2006-09-15
BG66015B1 (bg) 2010-10-29
PL205607B1 (pl) 2010-05-31
AU9025701A (en) 2002-04-15
NO20031407D0 (no) 2003-03-27
US20050065098A1 (en) 2005-03-24
AR030816A1 (es) 2003-09-03
BG107674A (bg) 2004-01-30
DK1329456T3 (da) 2006-12-04
PL362177A1 (en) 2004-10-18
NO327182B1 (no) 2009-05-04
JP3798375B2 (ja) 2006-07-19
HK1061037A1 (en) 2004-09-03
ES2269456T3 (es) 2007-04-01
EP1329456B1 (en) 2006-08-09
TWI284641B (en) 2007-08-01
UA73606C2 (en) 2005-08-15
IL155071A (en) 2010-04-15
PT1329456E (pt) 2006-12-29
BR0114310A (pt) 2003-10-14
CA2423568A1 (en) 2002-04-11
MY129023A (en) 2007-03-30
US6872706B2 (en) 2005-03-29
CA2423568C (en) 2011-03-15
CY1106076T1 (el) 2011-06-08
SK287811B6 (sk) 2011-10-04
EP1329456A4 (en) 2005-03-30
NZ524917A (en) 2005-01-28
ZA200302283B (en) 2005-05-27
EA005994B1 (ru) 2005-08-25
KR20030036867A (ko) 2003-05-09
IL155071A0 (en) 2003-10-31
EA200300316A1 (ru) 2003-08-28
DE60122193D1 (de) 2006-09-21
KR100647204B1 (ko) 2006-11-17
PE20020476A1 (es) 2002-07-04
CN1466590A (zh) 2004-01-07
SK3342003A3 (en) 2003-08-05
CN1293087C (zh) 2007-01-03
CZ303544B6 (cs) 2012-11-28
US20040018998A1 (en) 2004-01-29
DE60122193T2 (de) 2007-07-05
NO20031407L (no) 2003-04-30
AU2001290257B2 (en) 2007-08-30
HUP0301178A3 (en) 2009-08-28
HUP0301178A2 (hu) 2003-11-28
JPWO2002028872A1 (ja) 2004-02-12

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