MXPA97007996A - Preparado para el transporte de sustancias activas a traves de barreras. - Google Patents
Preparado para el transporte de sustancias activas a traves de barreras.Info
- Publication number
- MXPA97007996A MXPA97007996A MXPA97007996A MX9707996A MXPA97007996A MX PA97007996 A MXPA97007996 A MX PA97007996A MX PA97007996 A MXPA97007996 A MX PA97007996A MX 9707996 A MX9707996 A MX 9707996A MX PA97007996 A MXPA97007996 A MX PA97007996A
- Authority
- MX
- Mexico
- Prior art keywords
- preparation
- active substance
- transport
- barriers
- solubilization
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 6
- 239000013543 active substance Substances 0.000 title abstract 3
- 230000004888 barrier function Effects 0.000 title abstract 2
- 230000007928 solubilization Effects 0.000 abstract 2
- 238000005063 solubilization Methods 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Preparado para la aplicacion de sustancias activas en forma de gotas de liquido pequenisimas, particularmente con una envoltura tipo membrana de una o pocas capas de moleculas anfifilas, o bien, pequenas gotas de liquido provistas de una sustancia acarreadora, en particular para el transporte de la sustancia activa en y a traves de barreras naturales y constricciones, como pieles y similares. El preparado no presenta ningun punto de solubilizacion y la composicion del preparado, a una capacidad maxima de permeacion, esta lejos del punto de solubilizacion. El preparado presenta un contenido de al menos dos componentes, los cuales, en su solubilidad en el medio de suspension de los preparados, usualmente agua, se diferencian por al menos el factor 10.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4447287A DE4447287C1 (de) | 1994-12-30 | 1994-12-30 | Präparat zum Wirkstofftransport durch Barrieren |
| CNB961804734A CN1151777C (zh) | 1994-12-30 | 1996-10-17 | 转运活性成分通过屏障的制剂 |
| PCT/EP1996/004526 WO1998017255A1 (de) | 1994-12-30 | 1996-10-17 | Präparat zum wirkstofftransport durch barrieren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA97007996A true MXPA97007996A (es) | 2004-03-15 |
Family
ID=27179110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA97007996A MXPA97007996A (es) | 1994-12-30 | 1996-10-17 | Preparado para el transporte de sustancias activas a traves de barreras. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0935457B1 (es) |
| JP (1) | JP2001502676A (es) |
| KR (1) | KR100446832B1 (es) |
| CN (1) | CN1151777C (es) |
| AT (1) | ATE257373T1 (es) |
| AU (1) | AU724218B2 (es) |
| BR (1) | BR9612750A (es) |
| CA (1) | CA2268670A1 (es) |
| DE (2) | DE4447287C1 (es) |
| ES (1) | ES2211984T3 (es) |
| HU (1) | HUP9903363A3 (es) |
| MX (1) | MXPA97007996A (es) |
| WO (1) | WO1998017255A1 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4447287C1 (de) * | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
| EP1039880A1 (en) * | 1998-10-23 | 2000-10-04 | Idea Innovative Dermale Applikationen GmbH | Method for developing, testing and using associates of macromolecules and complex aggregates for improved payload and controllable de/association rates |
| JP2002528394A (ja) * | 1998-10-28 | 2002-09-03 | インビトロジェン コーポレイション | 植物細胞の成長を調節する化合物を含有する組成物、およびその使用方法 |
| HRP20010309B1 (en) | 1998-12-23 | 2005-06-30 | Idea Ag | Improved formulation for topical non-invasive application in vivo |
| ATE216223T1 (de) | 1999-01-27 | 2002-05-15 | Idea Ag | Transnasaler transport bzw. impfung mit hochadaptierbaren trägern |
| DE69901377T2 (de) | 1999-01-27 | 2003-01-02 | Idea Ag | Nichtinvasive Impfung durch die Haut |
| WO2001001962A1 (en) | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
| AU2136501A (en) * | 1999-12-10 | 2001-06-18 | Celator Technologies Inc. | Lipid carrier compositions with protected surface reactive functions |
| DK1551370T3 (da) * | 2002-10-11 | 2008-03-03 | Idea Ag | Aggregat med foröget deformerbarhed, som omfatter mindst tre amfipater, til forbedret transport gennem semipermeable barrierer og til ikke-invasiv lægemiddeltilförsel in vivo, især gennem huden |
| US7473432B2 (en) | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
| LT1585548T (lt) * | 2002-12-09 | 2018-09-25 | Abraxis Bioscience, Llc | Farmakologinių agentų kompozicijos ir įvedimo būdai |
| DE102008034098A1 (de) | 2008-07-21 | 2010-02-04 | Lts Lohmann Therapie-Systeme Ag | Zubereitung und lontophoretische Vorrichtung für die transdermale Anwendung von Wirkstoffen |
| CN102639113A (zh) | 2009-06-03 | 2012-08-15 | J·C·梅奥 | 用于治疗深部组织疼痛的制剂 |
| KR20120129864A (ko) | 2009-08-21 | 2012-11-28 | 타겟티드 딜리버리 테크놀러지스 리미티드 | 소포성 제형 |
| WO2013057208A1 (en) | 2011-10-18 | 2013-04-25 | Targeted Delivery Technologies Limited | Compositions and methods for reducing the proliferation and viability of microbial agents |
| CN102579350B (zh) * | 2012-03-02 | 2013-04-24 | 海南灵康制药有限公司 | 右旋布洛芬脂质体固体制剂 |
| GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
| ES2895910T3 (es) | 2015-06-30 | 2022-02-23 | Sequessome Tech Holdings Limited | Composiciones multifásicas |
| CH713023A2 (de) * | 2016-10-11 | 2018-04-13 | Kuhs Bernd | Verfahren zur Herstellung von dermatologischen und kosmetischen Präparaten mit ausgeprägten lamellaren Strukturen unter Verwendung von Phosphatidylcholin und biologischen Zellmaterialien, welche durch die Einwirkung von Ultraschallwellen aufgeschlossen werden und gleichzeitig zwischen den lamellaren Strukturen eingelagert werden. |
| WO2019023247A1 (en) | 2017-07-25 | 2019-01-31 | Immutics, Inc. | TREATMENT OF CANCER BY BLOCKING THE INTERACTION OF TIM-3 AND ITS LIGAND |
| EP3918323A4 (en) | 2019-01-30 | 2022-12-28 | TrueBinding, Inc. | ANTI-GAL3 ANTIBODIES AND USES THEREOF |
| CN110101591B (zh) * | 2019-05-23 | 2022-01-18 | 广州科斯曼生物科技有限公司 | 一种长效保湿组合物及其制备方法和应用 |
| WO2021242776A2 (en) | 2020-05-26 | 2021-12-02 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking galectin-3 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4921706A (en) * | 1984-11-20 | 1990-05-01 | Massachusetts Institute Of Technology | Unilamellar lipid vesicles and method for their formation |
| DE3542773A1 (de) * | 1985-12-04 | 1987-06-11 | Roehm Pharma Gmbh | Hautwirksame pharmaka mit liposomen als wirkstofftraeger |
| US5064655A (en) * | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
| FR2649155B1 (fr) * | 1989-06-28 | 1991-09-13 | Elf Aquitaine | Dispositif de mesure dynamometrique pour tige de forage |
| JP2844756B2 (ja) * | 1989-12-01 | 1999-01-06 | 日本新薬株式会社 | 脂肪乳剤 |
| WO1992003122A1 (de) * | 1990-08-24 | 1992-03-05 | Gregor Cevc | Präparat zur wirkstoffapplikation in kleinsttröpfchenform |
| SE9003100D0 (sv) * | 1990-09-28 | 1990-09-28 | Kabivitrum Ab | Lipid formulation system |
| SE9200951D0 (sv) * | 1992-03-27 | 1992-03-27 | Kabi Pharmacia Ab | Pharmaceutical composition containing a defined lipid system |
| SE9200952D0 (sv) * | 1992-03-27 | 1992-03-27 | Kabi Pharmacia Ab | Pharmaceutical carrier system containing defined lipids |
| FR2714601B1 (fr) * | 1993-12-30 | 1996-02-09 | Oreal | Composition dépigmentante pour le traitement simultané des couches superficielles et profondes, son utilisation. |
| JPH0881360A (ja) * | 1994-07-13 | 1996-03-26 | Wakamoto Pharmaceut Co Ltd | 安定な脂肪乳剤 |
| ATE223202T1 (de) * | 1994-09-30 | 2002-09-15 | Mika Pharma Ges Fuer Die Entwi | Pharmazeutische zusammensetzung |
| IT1270678B (it) * | 1994-10-20 | 1997-05-07 | Bayer Ag | Liposomi al chetoprofen |
| DE4447287C1 (de) * | 1994-12-30 | 1996-11-07 | Cevc Gregor | Präparat zum Wirkstofftransport durch Barrieren |
-
1994
- 1994-12-30 DE DE4447287A patent/DE4447287C1/de not_active Revoked
-
1996
- 1996-10-17 EP EP96934737A patent/EP0935457B1/de not_active Revoked
- 1996-10-17 CN CNB961804734A patent/CN1151777C/zh not_active Expired - Fee Related
- 1996-10-17 CA CA002268670A patent/CA2268670A1/en not_active Abandoned
- 1996-10-17 AU AU45108/97A patent/AU724218B2/en not_active Ceased
- 1996-10-17 BR BR9612750-3A patent/BR9612750A/pt not_active IP Right Cessation
- 1996-10-17 DE DE59610889T patent/DE59610889D1/de not_active Expired - Lifetime
- 1996-10-17 KR KR10-1999-7003375A patent/KR100446832B1/ko not_active Expired - Fee Related
- 1996-10-17 HU HU9903363A patent/HUP9903363A3/hu unknown
- 1996-10-17 MX MXPA97007996A patent/MXPA97007996A/es not_active IP Right Cessation
- 1996-10-17 JP JP10518859A patent/JP2001502676A/ja active Pending
- 1996-10-17 WO PCT/EP1996/004526 patent/WO1998017255A1/de not_active Ceased
- 1996-10-17 AT AT96934737T patent/ATE257373T1/de not_active IP Right Cessation
- 1996-10-17 ES ES96934737T patent/ES2211984T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9903363A3 (en) | 2008-04-28 |
| ES2211984T3 (es) | 2004-07-16 |
| KR20000049266A (ko) | 2000-07-25 |
| WO1998017255A1 (de) | 1998-04-30 |
| KR100446832B1 (ko) | 2004-09-04 |
| CN1234736A (zh) | 1999-11-10 |
| HUP9903363A2 (hu) | 2000-03-28 |
| HK1021622A1 (en) | 2000-06-23 |
| DE59610889D1 (de) | 2004-02-12 |
| ATE257373T1 (de) | 2004-01-15 |
| CN1151777C (zh) | 2004-06-02 |
| EP0935457A1 (de) | 1999-08-18 |
| CA2268670A1 (en) | 1998-04-30 |
| AU724218B2 (en) | 2000-09-14 |
| AU4510897A (en) | 1998-05-15 |
| BR9612750A (pt) | 1999-12-28 |
| EP0935457B1 (de) | 2004-01-07 |
| JP2001502676A (ja) | 2001-02-27 |
| DE4447287C1 (de) | 1996-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: IDEA AG |
|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |