MX9707843A - 4-amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds. - Google Patents
4-amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds.Info
- Publication number
- MX9707843A MX9707843A MX9707843A MX9707843A MX9707843A MX 9707843 A MX9707843 A MX 9707843A MX 9707843 A MX9707843 A MX 9707843A MX 9707843 A MX9707843 A MX 9707843A MX 9707843 A MX9707843 A MX 9707843A
- Authority
- MX
- Mexico
- Prior art keywords
- amino
- oxy
- trimethyl
- oxime
- hydrogen
- Prior art date
Links
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- 206010061340 Peripheral embolism Diseases 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
- SQDFHQJTAWCFIB-UHFFFAOYSA-N n-methylidenehydroxylamine Chemical compound ON=C SQDFHQJTAWCFIB-UHFFFAOYSA-N 0.000 abstract 1
- -1 nitro, carboxy Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 238000011699 spontaneously hypertensive rat Methods 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
4-Amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds represented by general formula (I), pharmacologically acceptable salts thereof, or solvates of these wherein R1 and R2 independently represent each hydrogen, optionally substituted alkyl or phenyl optionally having hydroxy, lower alkoxy, amino, nitro, carboxy, lower alkoxycarbonyl or halogeno on its ring, or R1 and R2 together with the nitrogen atom may form a nitrogen-containing heterocycle; R3 represents hydrogen, lower alkyl or lower aliphatic acyl; and W represents oxo, oxime or oxime ether. The compounds exert effects on a rat peripheral embolism model, a spontaneously hypertensive rat and a histamine-induced airway constriction model, which indicates that they are useful as a remedy for hypertension, peripheral embolism or bronchial asthma.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7-87294 | 1995-04-12 | ||
| JPJP7/87294 | 1995-04-12 | ||
| PCT/JP1996/001023 WO1996032370A1 (en) | 1995-04-12 | 1996-04-12 | 4-amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MXPA97007843A MXPA97007843A (en) | 1998-01-01 |
| MX9707843A true MX9707843A (en) | 1998-01-31 |
Family
ID=39165667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9707843A MX9707843A (en) | 1996-04-12 | 1996-04-12 | 4-amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds. |
Country Status (1)
| Country | Link |
|---|---|
| MX (1) | MX9707843A (en) |
-
1996
- 1996-04-12 MX MX9707843A patent/MX9707843A/en unknown
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