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MX9706851A - Variantes de subtilisina carlseberg que tienen adsorcion reducida e hidrolisis incrementada. - Google Patents

Variantes de subtilisina carlseberg que tienen adsorcion reducida e hidrolisis incrementada.

Info

Publication number
MX9706851A
MX9706851A MX9706851A MX9706851A MX9706851A MX 9706851 A MX9706851 A MX 9706851A MX 9706851 A MX9706851 A MX 9706851A MX 9706851 A MX9706851 A MX 9706851A MX 9706851 A MX9706851 A MX 9706851A
Authority
MX
Mexico
Prior art keywords
subtilisin carlsberg
loop region
wild
acid sequence
amino acid
Prior art date
Application number
MX9706851A
Other languages
English (en)
Inventor
Philip Frederik Brode Iii
Bobby Lee Barnett
Donn Nelton Rubingh
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MX9706851A publication Critical patent/MX9706851A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invencion se refiere a variantes de subtilisina Carlsberg que tienen una secuencia de aminoácidos modificada en la secuencia de aminoácidos de subtilisina Carlsberg tipo silvestre, la secuencia de aminoácidos tipo silvestre comprende una primera region de lazo, una segunda region de lazo, una tercera region de lazo, una cuarta region de lazo, y una quinta region de lazo y una sexta region de lazo; en donde la secuencia de aminoácidos modificada comprende diferentes aminoácidos de los que ocurren en la subtilisina Carlsberg de tipo silvestre (es decir, substitucion) en posiciones específicamente identificadas en una o más de las regiones de lazo, por lo que la variante de subtilisina Carlsberg tiene adsorcion reducida a, e hidrolisis incrementada de, un substrato insoluble en comparacion con la subtilisina Carlsberg de tipo silvestre; la presente invencion también se refiere a los genes que codifican dichas variantes de subtilisina Carlsberg; la presente invencion también se refiere a composiciones que comprenden dichas variantes de subtilisina Carlsberg para limpiar una variedad de superficies.
MX9706851A 1995-03-08 1996-02-14 Variantes de subtilisina carlseberg que tienen adsorcion reducida e hidrolisis incrementada. MX9706851A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/400,698 US6455295B1 (en) 1995-03-08 1995-03-08 Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis
PCT/US1996/002168 WO1996028566A2 (en) 1995-03-08 1996-02-14 Subtilisin carlsberg variants having decreased adsorption and increased hydrolysis

Publications (1)

Publication Number Publication Date
MX9706851A true MX9706851A (es) 1997-11-29

Family

ID=23584644

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9706851A MX9706851A (es) 1995-03-08 1996-02-14 Variantes de subtilisina carlseberg que tienen adsorcion reducida e hidrolisis incrementada.

Country Status (14)

Country Link
US (1) US6455295B1 (es)
EP (1) EP0813596A2 (es)
JP (1) JPH11501812A (es)
CN (1) CN1183119A (es)
AU (1) AU4868896A (es)
BR (1) BR9607356A (es)
CA (1) CA2214348C (es)
CZ (1) CZ279397A3 (es)
HU (1) HUP9800765A3 (es)
IL (1) IL117266A0 (es)
MA (1) MA23818A1 (es)
MX (1) MX9706851A (es)
WO (1) WO1996028566A2 (es)
ZA (1) ZA961631B (es)

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Also Published As

Publication number Publication date
CN1183119A (zh) 1998-05-27
HUP9800765A2 (hu) 1998-07-28
IL117266A0 (en) 1996-06-18
HUP9800765A3 (en) 2001-01-29
ZA961631B (en) 1996-09-06
EP0813596A2 (en) 1997-12-29
MA23818A1 (fr) 1996-10-01
CZ279397A3 (en) 1997-11-12
CA2214348A1 (en) 1996-09-19
CA2214348C (en) 2001-10-30
JPH11501812A (ja) 1999-02-16
WO1996028566A3 (en) 1997-07-10
US6455295B1 (en) 2002-09-24
BR9607356A (pt) 1999-06-15
AU4868896A (en) 1996-10-02
WO1996028566A2 (en) 1996-09-19

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