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MX9306222A - PHARMACEUTICAL COMPOSITIONS OF 2-OXINDOL-1-CARBOXAMIDES 3-SUBSTITUTED. - Google Patents

PHARMACEUTICAL COMPOSITIONS OF 2-OXINDOL-1-CARBOXAMIDES 3-SUBSTITUTED.

Info

Publication number
MX9306222A
MX9306222A MX9306222A MX9306222A MX9306222A MX 9306222 A MX9306222 A MX 9306222A MX 9306222 A MX9306222 A MX 9306222A MX 9306222 A MX9306222 A MX 9306222A MX 9306222 A MX9306222 A MX 9306222A
Authority
MX
Mexico
Prior art keywords
oxindol
carboxamides
substituted
pharmaceutical compositions
formula
Prior art date
Application number
MX9306222A
Other languages
Spanish (es)
Inventor
Imran Ahmed
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9306222A publication Critical patent/MX9306222A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Una preparación farmacéutica que comprenda: (A) al menos un triglicérido o diéster de propilenglicol de ácidos grasos de aceite de coco fraccionado; y (B) al menos un compuesto de fórmula (ver formula 1) donde R1, R2 y R3 son cada uno de ellos independientemente hidrógeno fluoro, bromo o cloro o sus sales farmacéuticamente aceptables.A pharmaceutical preparation comprising: (A) at least one triglyceride or diester of propylene glycol from fractionated coconut oil fatty acids; and (B) at least one compound of formula (see formula 1) wherein R1, R2 and R3 are each independently fluoro, bromo or chloro hydrogen or their pharmaceutically acceptable salts.

MX9306222A 1992-10-07 1993-10-06 PHARMACEUTICAL COMPOSITIONS OF 2-OXINDOL-1-CARBOXAMIDES 3-SUBSTITUTED. MX9306222A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95793092A 1992-10-07 1992-10-07

Publications (1)

Publication Number Publication Date
MX9306222A true MX9306222A (en) 1994-04-29

Family

ID=25500362

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306222A MX9306222A (en) 1992-10-07 1993-10-06 PHARMACEUTICAL COMPOSITIONS OF 2-OXINDOL-1-CARBOXAMIDES 3-SUBSTITUTED.

Country Status (21)

Country Link
EP (1) EP0662831A1 (en)
JP (1) JP2721042B2 (en)
KR (1) KR950703338A (en)
CN (1) CN1089138A (en)
AU (1) AU676200B2 (en)
BR (1) BR9307182A (en)
CA (1) CA2146448A1 (en)
CZ (1) CZ282702B6 (en)
EG (1) EG20289A (en)
FI (1) FI934387A7 (en)
HU (1) HUT68533A (en)
IL (1) IL107122A (en)
MX (1) MX9306222A (en)
MY (1) MY109680A (en)
NO (1) NO951350L (en)
NZ (1) NZ256164A (en)
PL (1) PL174170B1 (en)
RU (1) RU2119353C1 (en)
TW (1) TW438798B (en)
WO (1) WO1994007488A1 (en)
ZA (1) ZA937405B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2076106B1 (en) * 1993-08-26 1996-06-16 Pfizer PHARMACEUTICAL COMPOSITIONS BASED ON 2-OXINDOL-1-CARBOXAMIDES 3-SUBSTITUTED
AU2517095A (en) * 1994-05-19 1995-12-18 R.P. Scherer International Corporation Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
JPH10506635A (en) * 1995-04-24 1998-06-30 ファイザー・インコーポレーテッド Inhibition of photolysis of 3-substituted-2-oxindole
AU5340298A (en) * 1996-12-27 1998-07-31 Takeda Chemical Industries Ltd. Stabilized tricyclic compound
JP5869764B2 (en) * 2011-01-07 2016-02-24 中日本カプセル 株式会社 Capsule filling composition
WO2021077211A1 (en) * 2019-10-25 2021-04-29 Cardiol Therapeutics Inc. Cannabidiol compositions for use in treating heart conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
RO105052B1 (en) * 1987-02-02 1994-12-01 Pfizer Producing process for the crystalline sodium salt, anhydre, of 5-chlorine-3-(2-tenoil)-2-oxindol-1-carboxamide
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
CA2051621C (en) * 1990-03-02 2001-06-05 Shiseido Company, Ltd. Oil-in-water type emulsified composition comprising non-steroidal antiphlogistic and analgesic drug
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
EP0620728B1 (en) * 1992-01-13 1997-01-08 Pfizer Inc. Preparation of tablets of increased strength

Also Published As

Publication number Publication date
CZ282702B6 (en) 1997-09-17
BR9307182A (en) 1999-03-30
CN1089138A (en) 1994-07-13
WO1994007488A1 (en) 1994-04-14
EG20289A (en) 1998-07-30
AU676200B2 (en) 1997-03-06
MY109680A (en) 1997-04-30
FI934387L (en) 1994-04-08
AU4839293A (en) 1994-04-26
HU9302821D0 (en) 1993-12-28
PL174170B1 (en) 1998-06-30
NO951350D0 (en) 1995-04-06
KR950703338A (en) 1995-09-20
ZA937405B (en) 1995-04-06
EP0662831A1 (en) 1995-07-19
PL308307A1 (en) 1995-07-24
CA2146448A1 (en) 1994-04-14
IL107122A (en) 1998-08-16
CZ87895A3 (en) 1995-10-18
HUT68533A (en) 1995-04-27
JP2721042B2 (en) 1998-03-04
TW438798B (en) 2001-06-07
NO951350L (en) 1995-06-06
JPH07507809A (en) 1995-08-31
IL107122A0 (en) 1993-12-28
RU2119353C1 (en) 1998-09-27
NZ256164A (en) 1997-03-24
FI934387A7 (en) 1994-04-08
FI934387A0 (en) 1993-10-06

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