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MX9203034A - Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen. - Google Patents

Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen.

Info

Publication number
MX9203034A
MX9203034A MX9203034A MX9203034A MX9203034A MX 9203034 A MX9203034 A MX 9203034A MX 9203034 A MX9203034 A MX 9203034A MX 9203034 A MX9203034 A MX 9203034A MX 9203034 A MX9203034 A MX 9203034A
Authority
MX
Mexico
Prior art keywords
pteridines
group
chemotherapy
substituted
carbon atom
Prior art date
Application number
MX9203034A
Other languages
English (en)
Inventor
Armin Dr Heckel
Jorg Dr Lebsanft
Uwe Dr Bamberger
Avner Dr Ramu
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of MX9203034A publication Critical patent/MX9203034A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MX9203034A 1988-10-01 1992-06-19 Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen. MX9203034A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3833393A DE3833393A1 (de) 1988-10-01 1988-10-01 Verwendung von pteridinen zur verhinderung der primaeren und sekundaeren resistenz bei der chemotherapie und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
MX9203034A true MX9203034A (es) 1992-07-01

Family

ID=6364156

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9203034A MX9203034A (es) 1988-10-01 1992-06-19 Pteridinas que evitan la resistencia primaria y secundaria en la quimioterapia y medicamentos que las contienen.

Country Status (19)

Country Link
EP (1) EP0362645B1 (es)
JP (1) JPH02256676A (es)
KR (1) KR910006289A (es)
AT (1) ATE106728T1 (es)
AU (1) AU620645B2 (es)
DD (1) DD299062A5 (es)
DE (2) DE3833393A1 (es)
DK (1) DK480489A (es)
ES (1) ES2056174T3 (es)
FI (1) FI92699C (es)
HU (1) HU205761B (es)
IL (1) IL91814A (es)
MX (1) MX9203034A (es)
NO (1) NO175979C (es)
NZ (1) NZ230833A (es)
PT (1) PT91836B (es)
SU (1) SU1720491A3 (es)
UA (1) UA8028A1 (es)
ZA (1) ZA897414B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69920757T2 (de) * 1998-12-28 2005-12-15 4 AZA Bioscience N.V. Immunosuppressive wirkungen von pteridinderivaten
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
PL1663244T3 (pl) * 2003-09-12 2008-01-31 4 Aza Ip Nv Pochodne pterydyny do leczenia chorób związanych z TNF-alfa
AU2004283479A1 (en) * 2003-10-17 2005-05-06 4 Aza Bioscience Nv Heterocycle-substituted pteridine derivatives and their use in therapy
RU2447074C2 (ru) * 2005-05-12 2012-04-10 Тиботек Фармасьютикалз Лтд. Птеридины, полезные в качестве ингибиторов hcv, и способы получения птеридинов
US9259426B2 (en) 2006-07-20 2016-02-16 Gilead Sciences, Inc. 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
AU2016216673B2 (en) 2015-03-04 2017-02-02 Gilead Sciences, Inc. Toll like receptor modulator compounds
KR20160003575A (ko) 2015-11-09 2016-01-11 정민시 발전기용 동력전달장치
AU2017318601B2 (en) 2016-09-02 2020-09-03 Gilead Sciences, Inc. Toll like receptor modulator compounds
US10640499B2 (en) 2016-09-02 2020-05-05 Gilead Sciences, Inc. Toll like receptor modulator compounds
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202212339A (zh) 2019-04-17 2022-04-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI879779B (zh) 2019-06-28 2025-04-11 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574206A (en) * 1965-04-15 1971-04-06 Boehringer Sohn Ingelheim 2,7-dimorpholino-4-amino-6-phenyl-pteridines
NL129630C (es) * 1966-10-14
DE1617336C2 (de) * 1966-11-25 1982-07-01 C.H. Boehringer Sohn, 6507 Ingelheim Arzneimittel gegen Angina pectoris
DE1795515A1 (de) * 1967-08-18 1972-03-30 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Pteridinen
DE1795516A1 (de) * 1967-12-15 1972-01-27 Thomae Gmbh Dr K 4-AEthanolisopropanolamino-2-(2'-methylmorpholino)-7-morpholino-6-phenyl-pteridin
DE1921308A1 (de) * 1969-04-25 1971-01-07 Boehringer Sohn Ingelheim Herzwirksame Zubereitungen
US4767761A (en) * 1987-11-04 1988-08-30 Dana-Farber Cancer Institute, Inc. Ornithine derivatives and their use as methotrexate-resistant cell inhibitors

Also Published As

Publication number Publication date
FI92699C (fi) 1994-12-27
KR910006289A (ko) 1991-04-29
ES2056174T3 (es) 1994-10-01
ZA897414B (en) 1991-06-26
NO893879D0 (no) 1989-09-29
SU1720491A3 (ru) 1992-03-15
NZ230833A (en) 1991-05-28
JPH02256676A (ja) 1990-10-17
IL91814A0 (en) 1990-06-10
NO175979C (no) 1995-01-11
NO175979B (no) 1994-10-03
FI92699B (fi) 1994-09-15
AU4174989A (en) 1990-04-05
EP0362645B1 (de) 1994-06-08
DE58907824D1 (de) 1994-07-14
HU205761B (en) 1992-06-29
EP0362645A2 (de) 1990-04-11
ATE106728T1 (de) 1994-06-15
AU620645B2 (en) 1992-02-20
DK480489A (da) 1990-04-02
FI894615A7 (fi) 1990-04-02
DK480489D0 (da) 1989-09-29
FI894615A0 (fi) 1989-09-29
HUT52504A (en) 1990-07-28
DE3833393A1 (de) 1990-04-05
PT91836B (pt) 1995-07-18
NO893879L (no) 1990-04-02
DD299062A5 (de) 1992-03-26
PT91836A (pt) 1990-04-30
EP0362645A3 (de) 1992-03-25
IL91814A (en) 1994-02-27
UA8028A1 (uk) 1995-12-26

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