MX9201598A - Benzo piranona, procedimiento para su preparacion y utilizacion. - Google Patents
Benzo piranona, procedimiento para su preparacion y utilizacion.Info
- Publication number
- MX9201598A MX9201598A MX9201598A MX9201598A MX9201598A MX 9201598 A MX9201598 A MX 9201598A MX 9201598 A MX9201598 A MX 9201598A MX 9201598 A MX9201598 A MX 9201598A MX 9201598 A MX9201598 A MX 9201598A
- Authority
- MX
- Mexico
- Prior art keywords
- pct
- preparation
- piranona
- benzo
- procedure
- Prior art date
Links
- 150000004775 coumarins Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical class C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4111861A DE4111861A1 (de) | 1991-04-11 | 1991-04-11 | Benzopyranone, verfahren zu ihrer herstellung und verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9201598A true MX9201598A (es) | 1992-10-01 |
Family
ID=6429379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9201598A MX9201598A (es) | 1991-04-11 | 1992-04-07 | Benzo piranona, procedimiento para su preparacion y utilizacion. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5428038A (es) |
| EP (1) | EP0584091B1 (es) |
| JP (1) | JP3234221B2 (es) |
| AT (1) | ATE147736T1 (es) |
| AU (1) | AU658619B2 (es) |
| CA (1) | CA2108174A1 (es) |
| DE (2) | DE4111861A1 (es) |
| ES (1) | ES2097908T3 (es) |
| MX (1) | MX9201598A (es) |
| WO (1) | WO1992018493A1 (es) |
| ZA (1) | ZA922614B (es) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1048488C (zh) * | 1993-10-30 | 2000-01-19 | 山东省医学科学院药物研究所 | 抗病毒新化合物去氢柯子次酸甲酯及其制备方法 |
| CN1048489C (zh) * | 1993-10-30 | 2000-01-19 | 山东省医学科学院药物研究所 | 抗病毒新化合物短叶苏木酚酸甲酯及其制备方法 |
| ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| US6951862B2 (en) * | 1998-06-30 | 2005-10-04 | Neuromed Technologies, Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US6310059B1 (en) | 1998-06-30 | 2001-10-30 | Neuromed Technologies, Inc. | Fused ring calcium channel blockers |
| US20040259866A1 (en) * | 1998-06-30 | 2004-12-23 | Snutch Terrance P. | Calcium channel blockers comprising two benzhydril moieties |
| US6387897B1 (en) | 1998-06-30 | 2002-05-14 | Neuromed Technologies, Inc. | Preferentially substituted calcium channel blockers |
| US20040266784A1 (en) * | 1998-06-30 | 2004-12-30 | Snutch Terrance P. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
| US7186726B2 (en) * | 1998-06-30 | 2007-03-06 | Neuromed Pharmaceuticals Ltd. | Preferentially substituted calcium channel blockers |
| US6011035A (en) | 1998-06-30 | 2000-01-04 | Neuromed Technologies Inc. | Calcium channel blockers |
| US20060084660A1 (en) * | 1998-06-30 | 2006-04-20 | Neuromed Technologies Inc. | Calcium channel blockers comprising two benzhydril moieties |
| US6492375B2 (en) | 1998-06-30 | 2002-12-10 | Neuromed Technologies, Inc. | Partially saturated calcium channel blockers |
| US6943168B2 (en) * | 1998-06-30 | 2005-09-13 | Neuromed Technologies Inc. | Calcium channel inhibitors comprising benzhydril spaced from piperazine |
| JP2003518107A (ja) | 1999-12-20 | 2003-06-03 | ニューロメド テクノロジーズ， インコーポレイテッド | 部分飽和カルシウムチャネルブロッカー |
| DE10041574A1 (de) * | 2000-08-24 | 2002-03-07 | Merck Patent Gmbh | Chromenonderivate |
| CA2391239C (en) * | 2001-06-28 | 2009-01-20 | Dainippon Ink And Chemicals, Inc. | Benzopyran derivative and antiallergic agent |
| US20030199523A1 (en) * | 2002-02-28 | 2003-10-23 | Snutch Terrance P. | Heterocyclic calcium in channel blockers |
| USRE42327E1 (en) | 2002-06-14 | 2011-05-03 | Toyama Chemical Co., Ltd. | Medicinal compositions improving brain function and method for improving brain function |
| CA2496097A1 (en) * | 2002-08-23 | 2004-03-04 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
| BRPI0410871A (pt) * | 2003-05-30 | 2006-07-04 | Neuromed Tech Inc | 3-aminometil-pirrolidinas como bloqueadores do canal de cálcio do tipo n |
| HRP20030604A2 (en) * | 2003-07-25 | 2005-04-30 | Pliva-Istra�iva�ki institut d.o.o. | Substituted furochromenes, preparation thereof andtheir antiinflammatory action |
| HRP20030603A2 (en) * | 2003-07-25 | 2005-10-31 | Pliva-Istra�iva�ki institut d.o.o. | Substituted furochromene compounds of antiinflammatory action |
| US7507760B2 (en) * | 2004-01-22 | 2009-03-24 | Neuromed Pharmaceuticals Ltd. | N-type calcium channel blockers |
| US20050227999A1 (en) * | 2004-04-09 | 2005-10-13 | Neuromed Technologies Inc. | Diarylamine derivatives as calcium channel blockers |
| DE102004063910B4 (de) * | 2004-07-05 | 2006-12-28 | Bioplanta Arzneimittel Gmbh | Trisubstituierte Benzopyranone sowie diese enthaltende Pflanzenextrakte und Mittel |
| KR20070063526A (ko) * | 2004-08-30 | 2007-06-19 | 뉴로메드 파머큐티칼즈 리미티드 | 칼슘 채널 차단제인 우레아 유도체 |
| US7511077B2 (en) * | 2005-02-09 | 2009-03-31 | Neuromed Pharmaceuticals Ltd. | Diamine calcium channel blockers |
| EP1976841A4 (en) * | 2005-12-19 | 2010-07-28 | Neuromed Pharmaceuticals Ltd | HETEROCYCLIC AMIDDERIVES AS CALCIUM CHANNEL BLOCKERS |
| CA2643924A1 (en) * | 2006-04-17 | 2007-10-25 | Neuromed Pharmaceuticals Ltd. | Isoxazole derivatives as calcium channel blockers |
| WO2007133481A2 (en) * | 2006-05-11 | 2007-11-22 | Neuromed Pharmaceuticals Ltd. | Method for increasing the bioavailability of benzhydryl piperazine containing compounds |
| CA2653497A1 (en) * | 2006-05-26 | 2007-12-06 | Neuromed Pharmaceuticals Ltd. | Heterocyclic compounds as calcium channel blockers |
| CA2663280A1 (en) * | 2006-09-14 | 2008-03-20 | Neuromed Pharmaceuticals Ltd. | Diaryl piperidine compounds as calcium channel blockers |
| WO2008043183A1 (en) * | 2006-10-13 | 2008-04-17 | Neuromed Pharmaceuticals Ltd. | Cyclopropyl-piperazine compounds as calcium channel blockers |
| CN103491964A (zh) | 2011-03-08 | 2014-01-01 | 扎里卡斯药品有限公司 | 固体分散体制剂及其使用方法 |
| US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| CN102267971B (zh) * | 2011-08-03 | 2013-03-27 | 华中科技大学 | 脂环并[c]苯并吡喃酮衍生物及其应用 |
| ES2919779T3 (es) | 2017-06-20 | 2022-07-28 | Imbria Pharmaceuticals Inc | Derivado de 1-[(2,3,4-trimetoxifenil)metil]-piperazina, composiciones del mismo y métodos para aumentar la eficiencia del metabolismo cardíaco |
| US12318382B2 (en) | 2018-10-17 | 2025-06-03 | Imbria Pharmaceuticals, Inc. | Methods of treating rheumatic diseases using trimetazidine-based compounds |
| RU2705810C1 (ru) * | 2018-12-28 | 2019-11-12 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Противосудорожное средство |
| US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE884459Q (fr) * | 1971-05-14 | 1981-01-26 | Boehringer Mannheim Gmbh | Derives de la 4-(omega-(coumarine-7-yl-oxy)-alkyl)-piperazine et procede de preparation |
| DE3025385A1 (de) * | 1980-07-04 | 1982-01-28 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue tricyclische arylether, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel |
| US4569994A (en) * | 1983-09-19 | 1986-02-11 | Pennwalt Corporation | Dibenzo[b,d]pyranyloxyaminopropanols |
| US4558130A (en) * | 1984-03-27 | 1985-12-10 | Miles Laboratories, Inc. | Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide |
| DE3427985A1 (de) * | 1984-07-28 | 1986-01-30 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue 2h-l-benzopyran-2-on-derivate, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| DE3432239A1 (de) * | 1984-09-01 | 1986-03-13 | Standard Elektrik Lorenz Ag, 7000 Stuttgart | Optischer multiplexer/demultiplexer |
| US4701456A (en) * | 1984-09-19 | 1987-10-20 | Warner-Lambert Company | Aminoalkoxybenzopyranones as antipsychotic and anxiolytic agents |
| GB2168696B (en) * | 1984-12-21 | 1989-01-11 | Boehringer Biochemia Srl | Fluoro coumarins as antilymphoedema agents |
| IN163948B (es) * | 1986-01-17 | 1988-12-10 | Robins Co Inc A H | |
| KR890012971A (ko) * | 1988-02-10 | 1989-09-20 | 원본미기재 | 심장혈관 항히스타민제 및 분비억제제로서의 n-치환된-아릴알킬 및 아릴알킬렌 아미노헤테로사이클릭 화합물 |
| JP2974327B2 (ja) * | 1989-07-03 | 1999-11-10 | 三井化学株式会社 | ポリアルキル―２―アルコキシ―７―ヒドロキシクロマンの製造方法 |
| US5248784A (en) * | 1989-12-28 | 1993-09-28 | Mitsui Toatsu Chemicals, Inc. | 4-carbonyl-substituted coumarin compound |
-
1991
- 1991-04-11 DE DE4111861A patent/DE4111861A1/de not_active Withdrawn
-
1992
- 1992-04-02 EP EP92908141A patent/EP0584091B1/de not_active Expired - Lifetime
- 1992-04-02 AU AU15403/92A patent/AU658619B2/en not_active Ceased
- 1992-04-02 US US08/133,017 patent/US5428038A/en not_active Expired - Fee Related
- 1992-04-02 CA CA002108174A patent/CA2108174A1/en not_active Abandoned
- 1992-04-02 WO PCT/EP1992/000739 patent/WO1992018493A1/de not_active Ceased
- 1992-04-02 ES ES92908141T patent/ES2097908T3/es not_active Expired - Lifetime
- 1992-04-02 DE DE59207907T patent/DE59207907D1/de not_active Expired - Fee Related
- 1992-04-02 AT AT92908141T patent/ATE147736T1/de not_active IP Right Cessation
- 1992-04-02 JP JP50763392A patent/JP3234221B2/ja not_active Expired - Fee Related
- 1992-04-07 MX MX9201598A patent/MX9201598A/es unknown
- 1992-04-10 ZA ZA922614A patent/ZA922614B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0584091A1 (de) | 1994-03-02 |
| DE4111861A1 (de) | 1992-10-15 |
| WO1992018493A1 (de) | 1992-10-29 |
| EP0584091B1 (de) | 1997-01-15 |
| DE59207907D1 (de) | 1997-02-27 |
| AU1540392A (en) | 1992-11-17 |
| CA2108174A1 (en) | 1992-10-12 |
| JP3234221B2 (ja) | 2001-12-04 |
| US5428038A (en) | 1995-06-27 |
| AU658619B2 (en) | 1995-04-27 |
| JPH06506922A (ja) | 1994-08-04 |
| ES2097908T3 (es) | 1997-04-16 |
| ATE147736T1 (de) | 1997-02-15 |
| ZA922614B (en) | 1992-12-30 |
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