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MX387520B - Particulas de nicotina. - Google Patents

Particulas de nicotina.

Info

Publication number
MX387520B
MX387520B MX2018015119A MX2018015119A MX387520B MX 387520 B MX387520 B MX 387520B MX 2018015119 A MX2018015119 A MX 2018015119A MX 2018015119 A MX2018015119 A MX 2018015119A MX 387520 B MX387520 B MX 387520B
Authority
MX
Mexico
Prior art keywords
particles
nicotine particles
liquid mixture
nicotine
liquid
Prior art date
Application number
MX2018015119A
Other languages
English (en)
Other versions
MX2018015119A (es
Inventor
Nicolo Volpe
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of MX2018015119A publication Critical patent/MX2018015119A/es
Publication of MX387520B publication Critical patent/MX387520B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Addiction (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un método incluye combinar nicotina con un líquido portador para formar una mezcla líquida y secar por atomizado la mezcla líquida para formar una primera pluralidad de partículas. La primera pluralidad de partículas se mueles para formar una segunda pluralidad de partículas.
MX2018015119A 2016-06-30 2017-06-21 Particulas de nicotina. MX387520B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16177156 2016-06-30
PCT/IB2017/053710 WO2018002779A1 (en) 2016-06-30 2017-06-21 Nicotine particles

Publications (2)

Publication Number Publication Date
MX2018015119A MX2018015119A (es) 2019-04-15
MX387520B true MX387520B (es) 2025-03-18

Family

ID=56296658

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018015119A MX387520B (es) 2016-06-30 2017-06-21 Particulas de nicotina.

Country Status (18)

Country Link
US (2) US11458093B2 (es)
EP (1) EP3478265B1 (es)
JP (2) JP7471774B2 (es)
KR (1) KR102559152B1 (es)
CN (1) CN109310623B (es)
AU (1) AU2017290610A1 (es)
BR (1) BR112018075017A2 (es)
CA (1) CA3023626A1 (es)
ES (1) ES3005760T3 (es)
IL (1) IL263340A (es)
MX (1) MX387520B (es)
PH (1) PH12018502715A1 (es)
PL (1) PL3478265T3 (es)
RU (1) RU2741309C2 (es)
SG (1) SG11201809630RA (es)
UA (1) UA126853C2 (es)
WO (1) WO2018002779A1 (es)
ZA (1) ZA201807080B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017286864A1 (en) * 2016-06-30 2018-11-15 Philip Morris Products S.A. Nicotine particles and compositions
WO2018163085A1 (en) * 2017-03-07 2018-09-13 Philip Morris Products S.A. Inhalable nicotine formulations, and methods of making and using thereof
ES2965397T3 (es) 2019-11-14 2024-04-15 Philip Morris Products Sa Formulación mejorada de polvo seco con sabor a tabaco
US20230233459A1 (en) * 2020-06-15 2023-07-27 Philip Morris Products S.A. Anatabine powder compositions
KR20230061365A (ko) * 2020-09-03 2023-05-08 필립모리스 프로덕츠 에스.에이. 분무 건조 저 흡습성 활성 분말 조성물
MX2023002466A (es) * 2020-09-03 2023-05-19 Philip Morris Products Sa Composiciones en polvo activas de baja higroscopicidad.
US20220313678A1 (en) * 2021-04-06 2022-10-06 Altria Client Services Llc Spray dried nicotine for inclusion in oral products
USD1081739S1 (en) 2021-04-06 2025-07-01 Altria Client Services Llc Die for gum forming
US12295412B2 (en) 2022-01-28 2025-05-13 Altria Client Services Llc Oral pouch product
CN120500327A (zh) * 2022-10-27 2025-08-15 韩国烟草人参公社 用于吸入的低剂量尼古丁干粉组合物
EP4609855A1 (en) * 2022-10-27 2025-09-03 KT&G Corporation Method for manufacturing nicotine dry powder for inhalation

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4655231A (en) 1984-01-09 1987-04-07 Advanced Tobacco Products, Inc. Snuff and preparation thereof
JP3388896B2 (ja) * 1994-08-08 2003-03-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
CA2231968A1 (en) 1998-03-11 1999-09-11 Smoke-Stop, A Partnership Consisting Of Art Slutsky Method of producing a nicotine medicament
US20120042886A1 (en) 1998-03-11 2012-02-23 Hanna Piskorz Method of producing a nicotine medicament and a medicament made by the method
US20080138398A1 (en) 1999-07-16 2008-06-12 Aradigm Corporation Dual release nicotine formulations, and systems and methods for their use
US8256433B2 (en) 1999-07-16 2012-09-04 Aradigm Corporation Systems and methods for effecting cessation of tobacco use
US6799576B2 (en) 1999-07-16 2004-10-05 Aradigm Corporation System for effecting smoking cessation
US6586008B1 (en) * 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
GB0425758D0 (en) * 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
ITMI20051999A1 (it) 2005-10-21 2007-04-22 Eratech S R L Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita'
FI20060428A7 (fi) 2006-05-03 2007-11-04 Esko Kauppinen Pintamodifioidut aerosolihiukkaset, menetelmä ja laite niiden tuottamiseksi sekä jauheet ja dispersiot jotka sisältävät kyseisiä hiukkasia
US20080286340A1 (en) 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
CA2744655A1 (en) 2008-11-27 2010-06-03 Boehringer Ingelheim International Gmbh Novel powdered crystalline medicines for inhalation
KR20170070274A (ko) 2009-05-29 2017-06-21 펄 테라퓨틱스 인코포레이티드 지속형 무스카린 안타고니스트 및 지속형 ｂ₂아드레날린 수용체 아고니스트의 폐 전달용 조성물, 및 연관된 방법 및 시스템
US20150136130A1 (en) 2012-02-29 2015-05-21 Pulmatrix, Inc. Inhalable dry powders
SE536491C2 (sv) 2012-03-26 2013-12-27 Bionicotine Ab Påse innehållande nikotin och en tuggummikomposition
US20140261474A1 (en) 2013-03-15 2014-09-18 Aradigm Corporation Methods for inhalation of smoke-free nicotine
ITMI20130572A1 (it) 2013-04-10 2014-10-11 Eratech Srl Composizione comprendente almeno due polveri secche ottenute per spray dry per aumentare la stabilita' della formulazione
HUE069174T2 (hu) 2013-05-06 2025-02-28 Juul Labs Inc Nikotinsó készítmények aeroszolos eszközökhöz és ezek eljárásai
KR20190075168A (ko) * 2014-04-08 2019-06-28 필립모리스 프로덕츠 에스.에이. 니코틴 제형 및 이의 제조방법
JP6712232B2 (ja) * 2014-04-28 2020-06-17 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 風味付きニコチン粉末吸入器

Also Published As

Publication number Publication date
CA3023626A1 (en) 2018-01-04
US11458093B2 (en) 2022-10-04
JP2022116082A (ja) 2022-08-09
KR20190026655A (ko) 2019-03-13
JP7583764B2 (ja) 2024-11-14
JP7471774B2 (ja) 2024-04-22
ES3005760T3 (en) 2025-03-17
SG11201809630RA (en) 2018-11-29
RU2741309C2 (ru) 2021-01-25
AU2017290610A1 (en) 2018-11-15
US20230000767A1 (en) 2023-01-05
UA126853C2 (uk) 2023-02-15
RU2018144108A (ru) 2020-07-30
IL263340A (en) 2018-12-31
BR112018075017A2 (pt) 2019-03-19
US12048762B2 (en) 2024-07-30
MX2018015119A (es) 2019-04-15
EP3478265A1 (en) 2019-05-08
ZA201807080B (en) 2019-07-31
PH12018502715A1 (en) 2019-07-29
CN109310623B (zh) 2022-10-21
CN109310623A (zh) 2019-02-05
KR102559152B1 (ko) 2023-07-26
EP3478265B1 (en) 2025-01-01
US20190117567A1 (en) 2019-04-25
PL3478265T3 (pl) 2025-04-14
RU2018144108A3 (es) 2020-07-30
WO2018002779A1 (en) 2018-01-04
JP2019519542A (ja) 2019-07-11
EP3478265C0 (en) 2025-01-01

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