MX384888B - Material regenerativo de tejidos conectivos, tal como hueso, dentina o pulpa, que comprende silicato de calcio - Google Patents
Material regenerativo de tejidos conectivos, tal como hueso, dentina o pulpa, que comprende silicato de calcioInfo
- Publication number
- MX384888B MX384888B MX2019012248A MX2019012248A MX384888B MX 384888 B MX384888 B MX 384888B MX 2019012248 A MX2019012248 A MX 2019012248A MX 2019012248 A MX2019012248 A MX 2019012248A MX 384888 B MX384888 B MX 384888B
- Authority
- MX
- Mexico
- Prior art keywords
- calcium silicate
- regenerative material
- dentin
- bone
- pulp
- Prior art date
Links
- 239000000463 material Substances 0.000 title abstract 7
- 230000001172 regenerating effect Effects 0.000 title abstract 7
- 229910052918 calcium silicate Inorganic materials 0.000 title abstract 4
- 239000000378 calcium silicate Substances 0.000 title abstract 4
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 title abstract 4
- 210000002808 connective tissue Anatomy 0.000 title abstract 4
- 210000000988 bone and bone Anatomy 0.000 title abstract 3
- 239000011159 matrix material Substances 0.000 abstract 4
- 239000002245 particle Substances 0.000 abstract 3
- 239000011148 porous material Substances 0.000 abstract 3
- 210000004268 dentin Anatomy 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 238000001033 granulometry Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 230000002138 osteoinductive effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Composite Materials (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Abstract
La presente invención se refiere a un material regenerativo en el campo de regeneración de tejidos conectivos (tales como hueso, dentina o pulpa). Más precisamente, la presente invención se refiere a un material regenerativo de tejido conectivo, preferentemente un material regenerativo de hueso, dentina o pulpa, que comprende: - una matriz polimérica porosa que tiene poros interconectados; y - partículas de silicato de calcio no hidratadas; en donde: dicha matriz polimérica es anhidra; dichas partículas de silicato de calcio no hidratadas tienen una granulometría d50, que preferentemente varía de 0.05 µm a menos del tamaño de diámetro promedio de los poros de la matriz; y dichas partículas de silicato de calcio no hidratadas se recubren en las paredes interiores de los poros de la matriz. La presente invención también se refiere a un método para preparar dicho material regenerativo de tejido conectivo. La presente invención también se refiere a los usos de dichos materiales regenerativos, tales como por ejemplo en el campo dental; especialmente, para proporcionar materiales regenerativos con propiedades biomecánicas y osteoinductoras mejoradas (i.e., buena migración, adhesión y proliferación de células; propiedades mecánicas mejoradas y biodegradabilidad óptima y controlada).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17305444.6A EP3388092A1 (en) | 2017-04-13 | 2017-04-13 | Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate |
| EP17203635 | 2017-11-24 | ||
| PCT/EP2018/059563 WO2018189384A1 (en) | 2017-04-13 | 2018-04-13 | Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019012248A MX2019012248A (es) | 2020-02-07 |
| MX384888B true MX384888B (es) | 2025-03-14 |
Family
ID=61911631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019012248A MX384888B (es) | 2017-04-13 | 2018-04-13 | Material regenerativo de tejidos conectivos, tal como hueso, dentina o pulpa, que comprende silicato de calcio |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11160905B2 (es) |
| EP (1) | EP3609549B1 (es) |
| CN (1) | CN110869065B (es) |
| BR (1) | BR112019021533B1 (es) |
| CA (1) | CA3059646A1 (es) |
| ES (1) | ES2906850T3 (es) |
| MX (1) | MX384888B (es) |
| PL (1) | PL3609549T3 (es) |
| WO (1) | WO2018189384A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3818994A1 (en) * | 2019-11-08 | 2021-05-12 | Septodont ou Septodont SAS ou Specialites Septodont | Non-breaking filament for shaping bone and dental substitutes |
| CN113679887B (zh) * | 2020-05-18 | 2022-05-27 | 中国科学院化学研究所 | 一种生物活性复合材料在牙周骨缺损修复和/或牙周骨再生方面的应用 |
| KR102665324B1 (ko) * | 2022-03-03 | 2024-05-14 | 가톨릭대학교 산학협력단 | 3d 프린트용 복합소재, 이의 제조방법 및 이를 포함하는 3d 프린트 스텐트 |
| US20240148614A1 (en) * | 2022-11-03 | 2024-05-09 | The Catholic University Of Korea Industry-Academic Cooperation Foundation | Method of preparing new biomaterials for dental pulp regeneration and a composition of new biomaterials prepared accordingly |
| CN120361294A (zh) * | 2025-04-18 | 2025-07-25 | 北京大学第三医院（北京大学第三临床医学院） | 纳米粒子组合物及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE141493T1 (de) | 1992-02-10 | 1996-09-15 | Matsumoto Dental College | Knochenersatzwerkstoff und verfahren zu seiner herstellung |
| DE60006356T2 (de) | 1999-02-04 | 2004-09-09 | SDGI Holding, Inc., Wilmington | Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung |
| PL1680089T3 (pl) * | 2003-10-22 | 2014-03-31 | Lidds Ab | Kompozycja zawierająca biodegradowalną ceramikę hydratującą do kontrolowanego dostarczania leków |
| CN100391418C (zh) * | 2004-03-05 | 2008-06-04 | 中国科学院上海硅酸盐研究所 | 可降解多孔聚酯/硅酸钙生物活性复合支架、制备及用途 |
| CN1278745C (zh) * | 2004-11-21 | 2006-10-11 | 厦门大学 | 一种三维多孔组织工程支架材料及其制备方法 |
| WO2007030752A2 (en) * | 2005-09-09 | 2007-03-15 | University Of Arkansas At Little Rock | System and method for tissue generation and bone regeneration |
| US20080147197A1 (en) | 2006-12-14 | 2008-06-19 | Mckay William F | Biodegradable osteogenic porous biomedical implant with impermeable membrane |
| JP5328780B2 (ja) * | 2007-06-13 | 2013-10-30 | エフ エム シー コーポレーション | アルギネート被覆多糖ゲル含有発泡体複合物、その製法および用途 |
| JP2010139953A (ja) * | 2008-12-15 | 2010-06-24 | Hitachi Displays Ltd | 液晶表示装置 |
| WO2010094813A1 (es) * | 2009-02-10 | 2010-08-26 | Azurebio, S. L. | Material de regeneración ósea a partir de combinaciones de monetita con otros compuestos de calcio bioactivos |
| BR112012016074A2 (pt) * | 2009-12-31 | 2016-08-16 | Oxane Materials Inc | método para produzir uma partícula de cerâmica contendo micro-esfera ou poro, partícula cerâmica contendo micro-esfera ou poro, método para escorar fraturas abertas de formações subterrâneas, método para tratar zonas produtoras subterrâneas, método para produzir propantes, método para produzir formadores de micro-esfera ou poro, formador de micro-esfera ou poro, método para produzir um artigo de vidro-cerâmico, cerâmica, metal, ou combinações destes, artigo de vidro-cerâmico, cerâmica, metal, ou combinações destes, propante cerâmico contendo micro-esfera ou poro e material cerâmico. |
| EP2452667A1 (en) * | 2010-11-15 | 2012-05-16 | Septodont ou Septodont SAS ou Specialites Septodont | Endodontic sealing composition |
| CN102784014B (zh) * | 2012-08-14 | 2014-11-26 | 中国科学院深圳先进技术研究院 | 多孔性骨支架及其制备方法 |
| JP6739455B2 (ja) * | 2015-03-12 | 2020-08-12 | クロス・バイオサイエンシズ・ベー・フェー | 無水生体適合性複合材料 |
| CN105031718B (zh) * | 2015-08-27 | 2018-04-13 | 华南理工大学 | 基于3D‑Bioplotter打印技术的骨修复多孔复合支架及其制备方法 |
-
2018
- 2018-04-13 BR BR112019021533-6A patent/BR112019021533B1/pt active IP Right Grant
- 2018-04-13 WO PCT/EP2018/059563 patent/WO2018189384A1/en not_active Ceased
- 2018-04-13 MX MX2019012248A patent/MX384888B/es unknown
- 2018-04-13 EP EP18716308.4A patent/EP3609549B1/en active Active
- 2018-04-13 PL PL18716308T patent/PL3609549T3/pl unknown
- 2018-04-13 ES ES18716308T patent/ES2906850T3/es active Active
- 2018-04-13 US US16/604,442 patent/US11160905B2/en active Active
- 2018-04-13 CA CA3059646A patent/CA3059646A1/en active Pending
- 2018-04-13 CN CN201880024880.2A patent/CN110869065B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3609549A1 (en) | 2020-02-19 |
| CN110869065B (zh) | 2022-07-01 |
| US11160905B2 (en) | 2021-11-02 |
| MX2019012248A (es) | 2020-02-07 |
| EP3609549B1 (en) | 2021-12-08 |
| RU2019138446A3 (es) | 2021-07-29 |
| CA3059646A1 (en) | 2018-10-18 |
| PL3609549T3 (pl) | 2022-04-11 |
| BR112019021533A2 (pt) | 2020-05-12 |
| BR112019021533A8 (pt) | 2022-12-06 |
| BR112019021533B1 (pt) | 2023-02-14 |
| WO2018189384A1 (en) | 2018-10-18 |
| US20200155725A1 (en) | 2020-05-21 |
| ES2906850T3 (es) | 2022-04-20 |
| RU2019138446A (ru) | 2021-05-28 |
| CN110869065A (zh) | 2020-03-06 |
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