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MX2024011278A - Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer. - Google Patents

Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer.

Info

Publication number
MX2024011278A
MX2024011278A MX2024011278A MX2024011278A MX2024011278A MX 2024011278 A MX2024011278 A MX 2024011278A MX 2024011278 A MX2024011278 A MX 2024011278A MX 2024011278 A MX2024011278 A MX 2024011278A MX 2024011278 A MX2024011278 A MX 2024011278A
Authority
MX
Mexico
Prior art keywords
monotherapy
cancer
treatment
combination therapy
antagonist antibodies
Prior art date
Application number
MX2024011278A
Other languages
English (en)
Inventor
Amir Toporik
Amit Novik
Eran Ophir
Nels P Nielson
Zoya Alteber
Alissa M Chiasson
Assaf Menachem
Olga Leiderman
Tal Fridman-Kfir
Moran Galperin
Hadas Galon Tilleman
Dan Blat
Gad COJOCARU
Ziv Erlich
Evgeny Tatirovsky
Michal Perpinial
Iital Sever
Nadav Cohen
Original Assignee
Compugen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen Ltd filed Critical Compugen Ltd
Publication of MX2024011278A publication Critical patent/MX2024011278A/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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Abstract

La presente invención se dirige a anticuerpos anti-IL18-BP y usos de estos. La presente invención se dirige a monoterapia y tratamientos de combinación con, por ejemplo, anticuerpos inhibidores de puntos de control inmunitarios, como se describe en la presente.
MX2024011278A 2022-03-15 2023-03-15 Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer. MX2024011278A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202263320202P 2022-03-15 2022-03-15
US202263351242P 2022-06-10 2022-06-10
US202363478898P 2023-01-06 2023-01-06
PCT/US2023/064460 WO2023178192A1 (en) 2022-03-15 2023-03-15 Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer

Publications (1)

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MX2024011278A true MX2024011278A (es) 2024-09-25

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MX2024011278A MX2024011278A (es) 2022-03-15 2023-03-15 Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer.

Country Status (14)

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US (1) US20250297018A1 (es)
EP (1) EP4493195A1 (es)
JP (1) JP2025509832A (es)
KR (1) KR20240144422A (es)
AU (1) AU2023236289A1 (es)
CA (1) CA3259975A1 (es)
CL (1) CL2024002748A1 (es)
CO (1) CO2024012373A2 (es)
CR (1) CR20240379A (es)
DO (1) DOP2024000179A (es)
IL (1) IL314346A (es)
MX (1) MX2024011278A (es)
PE (1) PE20251671A1 (es)
WO (1) WO2023178192A1 (es)

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IL321948A (en) 2023-01-06 2025-09-01 Lassen Therapeutics Inc Anti-IL-18 BP antibodies
WO2024148241A1 (en) * 2023-01-06 2024-07-11 Lassen Therapeutics 1, Inc. Anti-il-18bp antibodies
CN120693345A (zh) 2023-01-06 2025-09-23 艾利妥 抗il18结合蛋白抗体及其使用方法
TW202515608A (zh) * 2023-06-26 2025-04-16 以色列商坎布根有限公司 Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途
CN117986360B (zh) * 2024-02-01 2024-08-27 生物岛实验室 Il18蛋白的特异性抗体及其制备方法与应用
WO2025213047A1 (en) * 2024-04-05 2025-10-09 Tizona Therapeutics, Inc. Anti-il-18bp antibodies, compositions comprising anti-il-18bp antibodies and methods of using anti-il-18bp antibodies

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