[go: up one dir, main page]

MX2022006592A - Sistema para producir carnes cultivadas, tejidos y productos asociados a partir de células. - Google Patents

Sistema para producir carnes cultivadas, tejidos y productos asociados a partir de células.

Info

Publication number
MX2022006592A
MX2022006592A MX2022006592A MX2022006592A MX2022006592A MX 2022006592 A MX2022006592 A MX 2022006592A MX 2022006592 A MX2022006592 A MX 2022006592A MX 2022006592 A MX2022006592 A MX 2022006592A MX 2022006592 A MX2022006592 A MX 2022006592A
Authority
MX
Mexico
Prior art keywords
fluid
unit configured
cell culture
cell
supply
Prior art date
Application number
MX2022006592A
Other languages
English (en)
Inventor
Po San Mario Chin
Kai Yi Carrie Chan
Chuen Wai Li
Original Assignee
Avant Meats Company Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avant Meats Company Ltd filed Critical Avant Meats Company Ltd
Publication of MX2022006592A publication Critical patent/MX2022006592A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L13/00Meat products; Meat meal; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L17/00Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656Adult fibroblasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0679Cells of the gastro-intestinal tract
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • C12N2310/141MicroRNAs, miRNAs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/105Insulin-like growth factors [IGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/11Epidermal growth factor [EGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2306Interleukin-6 (IL-6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2311Interleukin-11 (IL-11)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/33Insulin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/003D culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00Microcarriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/70Polysaccharides
    • C12N2533/74Alginate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Un sistema de cultivo celular que mejora la producción celular y reduce el costo del cultivo celular. El sistema mantiene una condición de cultivo óptima estabilizando el nivel de nutrientes y/o manteniendo un nivel mínimo de inhibidores de crecimiento en un medio de cultivo. El sistema comprende una unidad de cultivo celular configurada para retener al menos un tipo de célula; una unidad de medio fresco configurada para suministrar y recibir el primer fluido a la unidad de cultivo celular; una unidad de eliminación de desechos configurada para suministrar y recibir un segundo fluido de la unidad de medio fresco; y una unidad de diálisis configurada para extraer los desechos del primer fluido al segundo fluido y suministrar nutrientes desde el segundo fluido al primer fluido.
MX2022006592A 2019-12-02 2020-11-30 Sistema para producir carnes cultivadas, tejidos y productos asociados a partir de células. MX2022006592A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962942568P 2019-12-02 2019-12-02
PCT/IB2020/061257 WO2021111270A1 (en) 2019-12-02 2020-11-30 System for producing cultivated meats, tissues and associated products from cells

Publications (1)

Publication Number Publication Date
MX2022006592A true MX2022006592A (es) 2022-08-25

Family

ID=76221512

Family Applications (4)

Application Number Title Priority Date Filing Date
MX2022006590A MX2022006590A (es) 2019-12-02 2020-07-28 Metodos de produccion de carne por cultivo celular in vitro.
MX2022006593A MX2022006593A (es) 2019-12-02 2020-11-14 Métodos para cultivar células, preparación de un hidrolizado a partir de células y sus aplicaciones.
MX2022006591A MX2022006591A (es) 2019-12-02 2020-11-27 Métodos para mejorar el cultivo celular con proteínas específicas de cada especie o específicas de cada género y las aplicaciones de los mismos.
MX2022006592A MX2022006592A (es) 2019-12-02 2020-11-30 Sistema para producir carnes cultivadas, tejidos y productos asociados a partir de células.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
MX2022006590A MX2022006590A (es) 2019-12-02 2020-07-28 Metodos de produccion de carne por cultivo celular in vitro.
MX2022006593A MX2022006593A (es) 2019-12-02 2020-11-14 Métodos para cultivar células, preparación de un hidrolizado a partir de células y sus aplicaciones.
MX2022006591A MX2022006591A (es) 2019-12-02 2020-11-27 Métodos para mejorar el cultivo celular con proteínas específicas de cada especie o específicas de cada género y las aplicaciones de los mismos.

Country Status (16)

Country Link
US (3) US20240093153A1 (es)
EP (5) EP4069824A1 (es)
JP (5) JP2023507242A (es)
KR (5) KR20220110798A (es)
CN (5) CN115443330A (es)
AU (5) AU2020396360A1 (es)
BR (4) BR112022010814A2 (es)
CA (5) CA3163651A1 (es)
CO (4) CO2022009114A2 (es)
EC (4) ECSP22051770A (es)
IL (4) IL293492A (es)
MX (4) MX2022006590A (es)
PE (4) PE20221184A1 (es)
PH (4) PH12022551329A1 (es)
TW (1) TW202322704A (es)
WO (5) WO2021111196A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022010814A2 (pt) * 2019-12-02 2022-08-23 Avant Meats Company Ltd Métodos de produção de carne por cultivo de células in vitro
US11319520B1 (en) * 2021-09-21 2022-05-03 Upside Foods, Inc. Filter cake-based systems and methods for the cultivation of cells and cell biomass
CN114181888B (zh) * 2021-11-24 2023-12-08 汕头大学 一种浅色黄姑鱼鱼鳔细胞系的建立方法及应用
WO2023233340A1 (en) * 2022-06-02 2023-12-07 Avant Meats Company Limited Genetically engineered yeast cells, recombinant proteins produced thereof and applications thereof
WO2024028439A1 (en) 2022-08-03 2024-02-08 Novelty For Them Gmbh Complexed asthaxanthin undergoing a hypsochromic shift upon heating and application in food products
WO2024134658A1 (en) * 2022-12-22 2024-06-27 Sea2Cell Ltd. Compositions and methods for culturing cells of aquatic species
CN116751742B (zh) * 2023-06-29 2025-01-03 中国海洋大学 一种三文鱼肌肉卫星细胞提取方法
WO2025048697A1 (en) * 2023-08-25 2025-03-06 Re:Meat Ab A method for cultivating food and beverages in a bioreactor
CN117770404A (zh) * 2023-12-14 2024-03-29 中国海洋大学 一种基于3d打印的细胞培养鱼肉及其制备方法

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3418208A (en) * 1966-02-28 1968-12-24 Mobil Oil Corp Growing increased yields of micro-organisms
FR2594847B1 (fr) * 1986-02-25 1989-06-02 Moet Hennessy Rech Procede de preparation de polypeptides biologiquement actifs, polypeptides obtenus et compositions les contenant
DE3641824A1 (de) * 1986-12-06 1988-06-16 Bayer Ag Verfahren und vorrichtung zur kultivierung immobilisierter oder adhaerierter saeugerzellen sowie dessen verwendung bei der herstellung von proteinen
KR0131822B1 (ko) * 1988-05-23 1998-04-11 죤 에프. 튜은트 바이오 반응기 장치
ES2252893T3 (es) * 1991-11-20 2006-05-16 Innogenetics N.V. Granulos derivados de queratinocitos para el uso como sustancias para la curacion de heridas.
WO1999031222A1 (en) * 1997-12-18 1999-06-24 Willem Frederik Van Eelen Industrial scale production of meat from in vitro cell cultures
US8026096B1 (en) * 1998-10-08 2011-09-27 Protein Sciences Corporation In vivo active erythropoietin produced in insect cells
US6664104B2 (en) * 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
US20070122904A1 (en) 2000-09-29 2007-05-31 Unisearch Limited Method and apparatus for culturing cells
WO2003029261A2 (en) * 2001-07-13 2003-04-10 Deangelis Paul L Glycosaminoglycan polymers and methods of making and using same
JP2003047461A (ja) * 2001-07-31 2003-02-18 Astec:Kk アパタイトシ−トを用いた細胞の高密度細胞培養法及び培養装置、細胞培養モジュール
EP2047865A1 (en) * 2002-12-03 2009-04-15 Celltran Limited Pharmaceutical compositions of cell lysate and processes for the production and use thereof
EP1591527B1 (en) * 2003-01-23 2015-08-26 Ono Pharmaceutical Co., Ltd. Substance specific to human pd-1
WO2005121316A1 (en) * 2004-06-11 2005-12-22 Bernard O'brien Institute Of Microsurgery Tissue material and muscle derived matrix
EP1789063B1 (en) * 2004-09-17 2011-12-14 Jon Vein Tissue engineered meat for consumption and a method for producing tissue engineered meat for consumption
WO2007139747A1 (en) * 2006-05-22 2007-12-06 Biovest International Inc. Interface of a cultureware module in a cell culture system and installation method thereof
WO2008109880A1 (en) * 2007-03-08 2008-09-12 The Johns Hopkins University Bioreactor system for pharmacokinetic-pharmacodynamic analysis
US20080254167A1 (en) * 2007-04-10 2008-10-16 Solae, Llc Seafood Compositions Comprising Structured Protein Products
US20100197007A1 (en) * 2007-07-31 2010-08-05 Inserm(Institut National De La Sante Et De La Recherche Medicale) Method for Culturing Mammalian Stem Cells
WO2009024595A2 (en) * 2007-08-22 2009-02-26 Probiogen Ag Culture system and method for immunogenicity and immunofunction testing in vitro
CA2742583C (en) * 2008-11-04 2022-09-27 Viacyte, Inc. Stem cell aggregate suspension compositions and methods for differentiation thereof
US20130323708A1 (en) * 2009-07-01 2013-12-05 Massachusetts Institute Of Technology Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
US20110091604A1 (en) * 2009-10-21 2011-04-21 Seth Adrian Miller Synthetic meat
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
WO2011103359A2 (en) * 2010-02-17 2011-08-25 Inq Biosciences Corporation Culture systems, apparatus, and related methods and articles
GB201019932D0 (en) * 2010-11-24 2011-01-05 Imp Innovations Ltd Dimensional hollow fibre bioreactor systems for the maintenance, expansion, differentiation and harvesting of human stem cells and their progeny
EP2670715B1 (en) * 2011-01-31 2017-04-26 Red Patent B.V. Installation and method for biomass conversion into methane
JP2014520123A (ja) * 2011-06-17 2014-08-21 アムジエン・インコーポレーテツド Clec−2を使用して代謝性障害を治療または改善させる方法
EP2885415B1 (en) * 2012-08-17 2022-08-03 Easel Biotechnologies LLC Two stage production of higher alcohols
US20160251625A1 (en) * 2013-10-30 2016-09-01 The Curators Of The University Of Missouri Method for scalable skeletal muscle lineage specification and cultivation
CN103992385B (zh) 2014-05-22 2017-05-10 浙江海洋学院 一种大黄鱼鱼鳔抗氧化胶原肽及其制备方法和用途
CN104109705B (zh) * 2014-06-19 2017-10-31 广东省农业科学院蚕业与农产品加工研究所 一种酶法制备具有促进伤口愈合活性的海洋胶原蛋白肽的方法
CN104313098A (zh) 2014-10-28 2015-01-28 威海市桢昊生物技术有限公司 一种鱼鳔胶原蛋白粉的制取方法
AU2016218037B2 (en) * 2015-02-09 2020-12-17 Univercells Technologies S.A. System, apparatus and method for the production of cells and/or cell products
CN105219827B (zh) 2015-11-10 2020-09-01 浙江海洋学院 鱼鳔胶原蛋白多功能肽的制备方法
WO2018011805A2 (en) * 2016-07-11 2018-01-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Systems and methods for growing cells in vitro
SG10202100843TA (en) * 2016-07-28 2021-03-30 Fonterra Cooperative Group Ltd Dairy product and process
CN106749634B (zh) * 2017-01-17 2020-09-15 北京鸿顺养源生物科技有限公司 一种具有抗氧化活性的猪血红蛋白糖肽及其制备方法与应用
CN106805252A (zh) * 2017-01-22 2017-06-09 福州大学 一种鱼短肽及其在营养强化剂中的应用
CA3066060A1 (en) * 2017-06-07 2018-12-13 Wild Type, Inc. Ex vivo meat production
US12123025B2 (en) * 2017-07-15 2024-10-22 Aleph Farms Ltd. Cultured meat compositions
CN107400633B (zh) * 2017-08-17 2023-10-10 上海白泽医疗器械有限公司 中空纤维交换器及中空纤维交换式培养系统
JP6279801B1 (ja) * 2017-09-19 2018-02-14 株式会社らいむ 組成物およびその製造方法
US10669524B2 (en) * 2018-06-12 2020-06-02 Fork & Goode, Inc. Large scale cell culture system for making meat and associated products
CN108823072B (zh) * 2018-09-19 2023-08-15 青岛中科蓝智生物科技发展有限公司 一种微藻细胞的培养-采收一体化系统及方法
CN110117527A (zh) 2019-05-15 2019-08-13 刘宝全 一种干细胞代谢废物的强化排出方法
CN110257227B (zh) * 2019-06-20 2020-08-04 江南大学 一种用于动物细胞培养的生物反应器
CN110201000A (zh) * 2019-07-11 2019-09-06 广东海洋大学 一种具有促进创伤愈合作用的方格星虫酶解蛋白肽粉的制备方法及其应用
CN110317848B (zh) * 2019-08-08 2020-02-18 北京工商大学 一种胶原蛋白肽的制备方法
BR112022010814A2 (pt) * 2019-12-02 2022-08-23 Avant Meats Company Ltd Métodos de produção de carne por cultivo de células in vitro
US11306342B2 (en) 2019-12-02 2022-04-19 Avant Meats Company Limited Cell hydrolysate composition from cultivated cells and applications thereof

Also Published As

Publication number Publication date
PE20221183A1 (es) 2022-08-05
CO2022009121A2 (es) 2022-09-09
BR112022010817A2 (pt) 2022-08-23
EP4069861A1 (en) 2022-10-12
IL293493A (en) 2022-08-01
JP2023504218A (ja) 2023-02-01
CN115298319A (zh) 2022-11-04
PE20221184A1 (es) 2022-08-05
EP4068987A1 (en) 2022-10-12
CA3228282A1 (en) 2023-02-09
IL293492A (en) 2022-08-01
US20220025310A1 (en) 2022-01-27
US20220298480A1 (en) 2022-09-22
IL293495A (en) 2022-08-01
PH12022551330A1 (en) 2024-06-24
AU2020398072A1 (en) 2022-06-16
CO2022009114A2 (es) 2022-09-09
AU2020397620A1 (en) 2022-06-16
BR112022010822A2 (pt) 2022-08-23
CO2022009119A2 (es) 2022-09-09
AU2022324741A1 (en) 2024-02-15
EP4068987A4 (en) 2024-03-06
AU2020396377A1 (en) 2022-06-16
US20240093153A1 (en) 2024-03-21
TW202322704A (zh) 2023-06-16
AU2020396360A1 (en) 2022-06-16
MX2022006591A (es) 2022-08-25
KR20220110265A (ko) 2022-08-05
CN115397969A (zh) 2022-11-25
PE20221185A1 (es) 2022-08-05
PE20221274A1 (es) 2022-09-01
WO2021111270A1 (en) 2021-06-10
JP2023504216A (ja) 2023-02-01
KR20220110798A (ko) 2022-08-09
BR112022010816A2 (pt) 2022-08-23
KR20220110541A (ko) 2022-08-08
KR20240041372A (ko) 2024-03-29
EP4069821A1 (en) 2022-10-12
WO2021111263A1 (en) 2021-06-10
CA3163663A1 (en) 2021-06-10
CA3163662A1 (en) 2021-06-10
BR112022010814A2 (pt) 2022-08-23
CN115443330A (zh) 2022-12-06
ECSP22051770A (es) 2022-09-30
JP2023507242A (ja) 2023-02-21
WO2021111219A1 (en) 2021-06-10
KR20220111310A (ko) 2022-08-09
EP4069861A4 (en) 2024-06-26
PH12022551331A1 (en) 2024-06-24
CA3163651A1 (en) 2021-06-10
EP4381044A1 (en) 2024-06-12
CN115443072A (zh) 2022-12-06
CO2022009288A2 (es) 2022-09-09
JP2024528972A (ja) 2024-08-01
PH12022551338A1 (en) 2024-06-24
CN117957304A (zh) 2024-04-30
IL293494A (en) 2022-08-01
MX2022006590A (es) 2022-09-19
EP4069821A4 (en) 2024-04-03
WO2023012523A1 (en) 2023-02-09
ECSP22051779A (es) 2022-09-30
MX2022006593A (es) 2022-08-25
PH12022551329A1 (en) 2024-06-24
US12084641B2 (en) 2024-09-10
JP2023504217A (ja) 2023-02-01
CA3173727A1 (en) 2021-06-10
ECSP22052002A (es) 2022-09-30
WO2021111196A1 (en) 2021-06-10
ECSP22051806A (es) 2022-09-30
EP4069824A1 (en) 2022-10-12

Similar Documents

Publication Publication Date Title
MX2022006592A (es) Sistema para producir carnes cultivadas, tejidos y productos asociados a partir de células.
Gupta et al. Tune to immobilize lipases on polymer membranes: Techniques, factors and prospects
CO2018000152A2 (es) Sistema y método para el crecimiento y el procesamiento de biomasa
CL2011001926A1 (es) Biorreactor para el cultivo de celulas de mamiferos donde dicho biorreactor posee un volumen de al menos 4000 l y al menos un impulsor superior y al menos un impulsor de fondo, donde el impulsor superior es un impulsor de hidroplano; metodo de cultivo; sistema de bioreactor.
MX2016008251A (es) Medios para cultivo celular.
AR086772A1 (es) Variantes del promotor del gen gap que codifica gliceraldehido-3-fosfato deshidrogenasa
CO7170186A2 (es) Tratamiento híbrido de aguas residuales
AR089231A1 (es) Metodo de floculacion
AR114504A1 (es) Regeneración de plantas genéticamente modificadas
BR112013020217A2 (pt) método e biorreator para o cultivo de micro-organismos
AR092630A1 (es) Metodos y composiciones para prevenir la incorporacion erronea de norleucina en proteinas
MX2017008338A (es) Metodos de cultivo de una celula de mamifero.
MX2017002234A (es) Metodos de cultivo semicontinuo.
CY1111008T1 (el) Προϊον με ζωντανους προβιοτικους μικροοργανισμους
AR122838A1 (es) Electrodiálisis de sales de aminoácidos en celdas de tres compartimientos con membrana bipolar
BR112017006866A2 (pt) sistemas e métodos para processar compostos bio-orgânicos
BR112017000142A2 (pt) ajuste de ph para melhorar recuperação de criopreservação de bancos de células
MX383963B (es) Medios microbiológicos de crecimiento y métodos de utilización de los mismos.
WO2015177641A3 (en) Methods of oil production in microorganisms
BR112018074315A2 (pt) método para produzir óleo com ácidos graxos saturados reduzidos.
AR110582A1 (es) Métodos para producir biomasa rica en dha, ácido palmítico y proteínas con un microorganismo eucariota
RO201200018U1 (ro) Instalaţie pentru tratarea apelor reziduale menajere
MX2021012649A (es) Medio de cultivo celular para celulas eucarioticas.
AR099811A1 (es) Microorganismos con una productividad de aminoácidos l mejorada y proceso para producir aminoácidos l
BR112016018797A8 (pt) aperfeiçoamento de expressão de proteína recombinante com o uso de um sistema de retenção de célula baseado em membrana