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MX2022004372A - Composiciones, métodos y kits para la estabilización de muestras biológicas y de arn. - Google Patents

Composiciones, métodos y kits para la estabilización de muestras biológicas y de arn.

Info

Publication number
MX2022004372A
MX2022004372A MX2022004372A MX2022004372A MX2022004372A MX 2022004372 A MX2022004372 A MX 2022004372A MX 2022004372 A MX2022004372 A MX 2022004372A MX 2022004372 A MX2022004372 A MX 2022004372A MX 2022004372 A MX2022004372 A MX 2022004372A
Authority
MX
Mexico
Prior art keywords
biological
kits
stabilization
compositions
methods
Prior art date
Application number
MX2022004372A
Other languages
English (en)
Inventor
Mark Kidd
Irvin Mark Modlin
Ignat Drozdov
Original Assignee
Liquid Biopsy Res Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liquid Biopsy Res Llc filed Critical Liquid Biopsy Res Llc
Publication of MX2022004372A publication Critical patent/MX2022004372A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente divulgación proporciona una solución amortiguadora que comprende al menos un agente caotrópico, al menos un agente quelante y al menos un tensoactivo no iónico, en donde la solución amortiguadora estabiliza una muestra biológica a temperatura ambiente durante al menos un día.
MX2022004372A 2019-10-10 2020-10-08 Composiciones, métodos y kits para la estabilización de muestras biológicas y de arn. MX2022004372A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962913458P 2019-10-10 2019-10-10
PCT/US2020/054719 WO2021072035A1 (en) 2019-10-10 2020-10-08 Compositions, methods and kits for biological sample and rna stabilization

Publications (1)

Publication Number Publication Date
MX2022004372A true MX2022004372A (es) 2022-07-27

Family

ID=73020311

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022004372A MX2022004372A (es) 2019-10-10 2020-10-08 Composiciones, métodos y kits para la estabilización de muestras biológicas y de arn.

Country Status (12)

Country Link
US (2) US20210108259A1 (es)
EP (1) EP4041886A1 (es)
JP (2) JP2022553914A (es)
KR (1) KR20220078659A (es)
CN (1) CN114901819A (es)
AU (1) AU2020363786A1 (es)
BR (1) BR112022006874A2 (es)
CA (1) CA3154045A1 (es)
IL (1) IL292053A (es)
MX (1) MX2022004372A (es)
TW (1) TW202128995A (es)
WO (1) WO2021072035A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021257844A1 (en) 2020-06-18 2021-12-23 The Board Of Trustees Of The University Of Illinois Saliva-based molecular testing for sars-cov-2
WO2023015232A1 (en) * 2021-08-04 2023-02-09 The Regents Of The University Of California Sars-cov-2 virus-like particles
JP2024537847A (ja) * 2021-10-01 2024-10-16 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム ＣＯＶＩＤ１９ ｍＲＮＡワクチン

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US100119A (en) 1870-02-22 colby
DE10006662A1 (de) * 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
MX351779B (es) 2011-03-01 2017-10-27 Univ Yale Prediccion de neoplasmas neuroendocrinos gastroenteropancreaticos (gep-nens).
JP2014513557A (ja) * 2011-05-17 2014-06-05 ディクステリティー ダイアグノスティクス インコーポレイテッド 標的核酸を検出する方法及び組成物
KR102538394B1 (ko) * 2014-06-10 2023-06-01 디엑스테리티 다이아그노스틱스 인코포레이티드 생물학적 샘플의 수집 및 안정화용 장치 및 방법
DK3194618T3 (da) 2014-09-15 2021-07-12 Clifton Life Sciences LLC Sammensætninger, fremgangsmåder og kits til diagnosticering af et gastroenteropankreatisk neuroendokrin neoplasma
JP6682734B2 (ja) * 2015-01-27 2020-04-15 ビージーアイ シェンチェン 生体試料を保存するための安定化剤
WO2017198715A1 (en) * 2016-05-17 2017-11-23 R-Biopharm Ag Nucleic acid stabilization agent
EP3631017B1 (en) 2017-05-25 2022-03-23 Liquid Biopsy Research LLC Methods for melanoma detection
BR112020000791A2 (pt) 2017-07-21 2020-07-21 Liquid Biopsy Research LLC métodos para detecção de discrasia de célula plasmática
AU2018375376B2 (en) 2017-11-30 2025-05-01 Liquid Biopsy Research LLC Predicting peptide receptor radiotherapy using a gene expression assay
DK3743534T3 (da) 2018-01-22 2022-06-20 Liquid Biopsy Res Llc Fremgangsmåde til påvisning af coloncancer og behandlingsovervågning
DK3755816T3 (da) 2018-02-22 2025-04-28 Liquid Biopsy Res Llc Fremgangsmåder til påvisning og behandling af prostatacancer

Also Published As

Publication number Publication date
US20210108259A1 (en) 2021-04-15
AU2020363786A1 (en) 2022-05-12
CN114901819A (zh) 2022-08-12
TW202128995A (zh) 2021-08-01
JP2025149974A (ja) 2025-10-08
KR20220078659A (ko) 2022-06-10
US20250327118A1 (en) 2025-10-23
JP2022553914A (ja) 2022-12-27
EP4041886A1 (en) 2022-08-17
WO2021072035A1 (en) 2021-04-15
BR112022006874A2 (pt) 2022-07-05
IL292053A (en) 2022-06-01
CA3154045A1 (en) 2021-04-15

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