MX2019003567A - Peptidos terapeuticos relacionados con mots-c. - Google Patents
Peptidos terapeuticos relacionados con mots-c.Info
- Publication number
- MX2019003567A MX2019003567A MX2019003567A MX2019003567A MX2019003567A MX 2019003567 A MX2019003567 A MX 2019003567A MX 2019003567 A MX2019003567 A MX 2019003567A MX 2019003567 A MX2019003567 A MX 2019003567A MX 2019003567 A MX2019003567 A MX 2019003567A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- mots
- therapeutic peptides
- peptides related
- treating
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000016097 disease of metabolism Diseases 0.000 abstract 1
- 230000004129 fatty acid metabolism Effects 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Child & Adolescent Psychology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
Abstract
La presente invención se refiere a péptidos y análogos peptídicos y métodos para tratar una enfermedad metabólica, por ejemplo, obesidad, diabetes, métodos para tratar cáncer, métodos para tratar una enfermedad hepática, y métodos para modular el metabolismo del ácido graso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662401123P | 2016-09-28 | 2016-09-28 | |
| PCT/US2017/053597 WO2018064098A1 (en) | 2016-09-28 | 2017-09-27 | Therapeutic mots-c related peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019003567A true MX2019003567A (es) | 2019-12-02 |
| MX392374B MX392374B (es) | 2025-03-24 |
Family
ID=60164788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019003567A MX392374B (es) | 2016-09-28 | 2017-09-27 | Peptidos terapeuticos relacionados con mots-c. |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11111271B2 (es) |
| EP (1) | EP3519431A1 (es) |
| JP (1) | JP7035033B2 (es) |
| KR (1) | KR20190057110A (es) |
| CN (1) | CN110072883A (es) |
| AU (1) | AU2017336440B2 (es) |
| CA (1) | CA3038292A1 (es) |
| IL (1) | IL265463A (es) |
| MX (1) | MX392374B (es) |
| TW (1) | TW201819398A (es) |
| WO (1) | WO2018064098A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190057110A (ko) * | 2016-09-28 | 2019-05-27 | 코바, 인크. | 치료적 mots-c 관련 펩타이드 |
| AU2019243724A1 (en) | 2018-03-27 | 2020-10-29 | Cohbar, Inc. | Peptide-containing formulations |
| EP3804705B1 (en) * | 2018-06-07 | 2023-09-13 | Hanyi Bio-Technology Company Ltd. | Pharmaceutical composition for preventing diabetes and use thereof |
| CN113518784A (zh) * | 2019-01-28 | 2021-10-19 | 科巴公司 | 治疗性肽 |
| CN110818804B (zh) * | 2019-10-21 | 2021-06-04 | 兰州大学 | 脑靶向肽及其在制备增强记忆药物中的应用 |
| CN115867648A (zh) * | 2020-02-14 | 2023-03-28 | 西北大学 | 将用于遗传密码重编程的化学底物扩展至包括长链碳和环状氨基酸 |
| EP4262880A1 (en) | 2020-12-21 | 2023-10-25 | Cornell University | Peptide-linked drug delivery system |
| CN113440599A (zh) * | 2021-08-11 | 2021-09-28 | 南京市妇幼保健院 | MOTS-c肽及其衍生物在制备妊娠期糖尿病治疗药物中的应用 |
| CN113876929B (zh) * | 2021-11-22 | 2024-02-23 | 中国人民解放军陆军军医大学 | 肽MOTS-c在制备治疗帕金森药物中的应用 |
| CN115444926A (zh) * | 2022-05-10 | 2022-12-09 | 江南大学 | MOTS-c肽及其衍生物在制备放射性肺损伤治疗药物中的应用 |
| WO2023249904A1 (en) * | 2022-06-20 | 2023-12-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating diabetes |
| US12064467B2 (en) * | 2022-10-28 | 2024-08-20 | Transdermal Biotechnology, Inc. | Systems and methods for delivery of humanin or other peptides |
| CN119241659B (zh) * | 2024-10-08 | 2025-09-19 | 西北大学 | MOTS-c及其氨基酸突变多肽在伤口愈合方面的用途 |
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| EP0272253A4 (en) | 1986-03-07 | 1990-02-05 | Massachusetts Inst Technology | METHOD FOR IMPROVING GLYCOPROTE INSTABILITY. |
| US5858351A (en) | 1996-01-18 | 1999-01-12 | Avigen, Inc. | Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors |
| US5846528A (en) | 1996-01-18 | 1998-12-08 | Avigen, Inc. | Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence |
| US6015709A (en) | 1997-08-26 | 2000-01-18 | Ariad Pharmaceuticals, Inc. | Transcriptional activators, and compositions and uses related thereto |
| AU2001251507A1 (en) | 2000-04-11 | 2001-10-23 | Cogent Neuroscience, Inc. | Compositions and methods for diagnosing and treating conditions, disorders, or diseases involving cell death |
| ATE280590T1 (de) | 2000-05-23 | 2004-11-15 | Neurologix Inc | Glutaminsäure decarboxylase (gad) abgabesystem zur behandlung neurodegeneraliver erkrankungen |
| US7588757B2 (en) | 2001-03-14 | 2009-09-15 | Genzyme Corporation | Methods of treating Parkinson's disease using recombinant adeno-associated virus virions |
| JP4769417B2 (ja) | 2001-12-17 | 2011-09-07 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | アデノ随伴ウイルス(aav)血清型9の配列、それを含むベクターおよびその使用 |
| WO2003104413A2 (en) | 2002-06-05 | 2003-12-18 | University Of Florida | Production of pseudotyped recombinant aav virions |
| EP1587540B1 (en) | 2003-01-09 | 2021-09-15 | MacroGenics, Inc. | IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME |
| US20040258666A1 (en) | 2003-05-01 | 2004-12-23 | Passini Marco A. | Gene therapy for neurometabolic disorders |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| US8283151B2 (en) | 2005-04-29 | 2012-10-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes |
| EP1857552A1 (en) | 2006-05-20 | 2007-11-21 | Cargill Incorporated | Thermostable xylose isomerase enzyme |
| US7846445B2 (en) | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
| AR059371A1 (es) | 2006-02-08 | 2008-03-26 | Genzyme Corp | Terapia genica para la enfermedad de niemann-pick tipo a |
| EP2007795B1 (en) | 2006-03-30 | 2016-11-16 | The Board Of Trustees Of The Leland Stanford Junior University | Aav capsid proteins |
| US8292769B2 (en) | 2006-11-22 | 2012-10-23 | Lawson Jr Thomas Towles | Transmission |
| US8309525B2 (en) | 2007-05-30 | 2012-11-13 | Albert Einstein College Of Medicine Of Yeshiva University | Treatment of type 2 diabetes, metabolic syndrome, myocardial injury and neurodegeneration with humanin and analogs thereof |
| AU2008269954A1 (en) * | 2007-06-29 | 2009-01-08 | Centocor Ortho Biotech Inc. | Anti- MCP-1 antibodies, compositions, methods and uses |
| BRPI0815416A2 (pt) | 2007-08-15 | 2014-10-21 | Amunix Inc | Composições e métodos para modificar propriedades de polipeptídeos biologicamente ativos |
| US7998928B2 (en) | 2007-09-14 | 2011-08-16 | The Regents Of The University Of California | Method of treatment of type-1 diabetes with a humanin analogue |
| TWI573806B (zh) | 2008-04-17 | 2017-03-11 | 巴克斯歐塔公司 | 生物活性胜肽 |
| WO2009135165A2 (en) | 2008-05-01 | 2009-11-05 | The Regents Of The University Of California | Small humanin-like peptides |
| US9217155B2 (en) | 2008-05-28 | 2015-12-22 | University Of Massachusetts | Isolation of novel AAV'S and uses thereof |
| CN102325539A (zh) | 2008-12-19 | 2012-01-18 | 印第安纳大学研究及科技有限公司 | 基于酰胺的胰高血糖素超家族肽前药 |
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| EP3514232A1 (en) | 2010-04-23 | 2019-07-24 | University of Massachusetts | Cns targeting aav vectors and methods of use thereof |
| US20120121633A1 (en) * | 2010-07-16 | 2012-05-17 | Sudhir Paul | Hiv cd4 binding site based covalent immunogen compositions |
| CN107828820B (zh) | 2010-10-27 | 2022-06-07 | 学校法人自治医科大学 | 用于向神经系统细胞导入基因的腺相关病毒粒子 |
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| US20130123168A1 (en) | 2011-06-17 | 2013-05-16 | The Regents Of The University Of California | Humanin and humanin-analogues for the management of atherosclerosis |
| US20140296139A1 (en) * | 2013-03-15 | 2014-10-02 | The Regents Of The University Of California | Mitochondrial-derived peptide mots3 regulates metabolism and cell survival |
| CN105324125A (zh) | 2013-03-15 | 2016-02-10 | 印第安纳大学研究及科技有限公司 | 具有长效的前体药物 |
| RU2692251C2 (ru) | 2013-05-15 | 2019-06-24 | Риджентс Оф Зэ Юниверсити Оф Миннесота | Опосредованный аденоассоциированным вирусом перенос генов в центральную нервную систему |
| EP4600255A3 (en) | 2014-05-02 | 2025-10-22 | Genzyme Corporation | Aav vectors for retinal and cns gene therapy |
| CN107106689A (zh) | 2014-11-05 | 2017-08-29 | 沃雅戈治疗公司 | 用于治疗帕金森病的aadc多核苷酸 |
| MA41451A (fr) | 2015-02-04 | 2017-12-12 | Univ Washington | Constructions anti-tau |
| KR20190057110A (ko) * | 2016-09-28 | 2019-05-27 | 코바, 인크. | 치료적 mots-c 관련 펩타이드 |
-
2017
- 2017-09-27 KR KR1020197012168A patent/KR20190057110A/ko not_active Ceased
- 2017-09-27 CA CA3038292A patent/CA3038292A1/en active Pending
- 2017-09-27 US US16/336,089 patent/US11111271B2/en not_active Expired - Fee Related
- 2017-09-27 WO PCT/US2017/053597 patent/WO2018064098A1/en not_active Ceased
- 2017-09-27 JP JP2019517875A patent/JP7035033B2/ja not_active Expired - Fee Related
- 2017-09-27 TW TW106133165A patent/TW201819398A/zh unknown
- 2017-09-27 MX MX2019003567A patent/MX392374B/es unknown
- 2017-09-27 CN CN201780059877.XA patent/CN110072883A/zh active Pending
- 2017-09-27 EP EP17788342.8A patent/EP3519431A1/en not_active Withdrawn
- 2017-09-27 AU AU2017336440A patent/AU2017336440B2/en not_active Ceased
-
2019
- 2019-03-19 IL IL265463A patent/IL265463A/en unknown
-
2021
- 2021-08-04 US US17/393,944 patent/US11332497B2/en active Active
-
2022
- 2022-04-11 US US17/717,982 patent/US11753445B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN110072883A (zh) | 2019-07-30 |
| EP3519431A1 (en) | 2019-08-07 |
| WO2018064098A1 (en) | 2018-04-05 |
| US20210363187A1 (en) | 2021-11-25 |
| IL265463A (en) | 2019-05-30 |
| US11332497B2 (en) | 2022-05-17 |
| JP2020501514A (ja) | 2020-01-23 |
| AU2017336440B2 (en) | 2022-06-02 |
| US20200181197A1 (en) | 2020-06-11 |
| KR20190057110A (ko) | 2019-05-27 |
| US11111271B2 (en) | 2021-09-07 |
| AU2017336440A1 (en) | 2019-04-11 |
| TW201819398A (zh) | 2018-06-01 |
| JP7035033B2 (ja) | 2022-03-14 |
| US20220242912A1 (en) | 2022-08-04 |
| MX392374B (es) | 2025-03-24 |
| US11753445B2 (en) | 2023-09-12 |
| CA3038292A1 (en) | 2018-04-05 |
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