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MX2018008523A - Bacterias que utilizan el acido lactico geneticamente modificadas para secretar enzimas degradantes de los polisacaridos. - Google Patents

Bacterias que utilizan el acido lactico geneticamente modificadas para secretar enzimas degradantes de los polisacaridos.

Info

Publication number
MX2018008523A
MX2018008523A MX2018008523A MX2018008523A MX2018008523A MX 2018008523 A MX2018008523 A MX 2018008523A MX 2018008523 A MX2018008523 A MX 2018008523A MX 2018008523 A MX2018008523 A MX 2018008523A MX 2018008523 A MX2018008523 A MX 2018008523A
Authority
MX
Mexico
Prior art keywords
lactic acid
degrading enzymes
utilizing bacteria
genetically modified
polysaccharide
Prior art date
Application number
MX2018008523A
Other languages
English (en)
Inventor
Shapira Tal
Oranim Amir
Original Assignee
3Plw Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3Plw Ltd filed Critical 3Plw Ltd
Publication of MX2018008523A publication Critical patent/MX2018008523A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F3/00—Biological treatment of water, waste water, or sewage
    • C02F3/34—Biological treatment of water, waste water, or sewage characterised by the microorganisms used
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2103/00—Nature of the water, waste water, sewage or sludge to be treated
    • C02F2103/32—Nature of the water, waste water, sewage or sludge to be treated from the food or foodstuff industry, e.g. brewery waste waters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hydrology & Water Resources (AREA)
  • Environmental & Geological Engineering (AREA)
  • Water Supply & Treatment (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

Se proporcionan bacterias que utilizan ácido láctico (LA), modificadas genéticamente para expresar y opcionalmente secretar enzimas que degradan polisacáridos, tales como celulasas, hemicelulasas y amilasas, y sus usos. Las enzimas que degradan polisacáridos son ventajosas para procesar desecho orgánico de manera que el desecho orgánico puede usarse como un sustrato en procesos industriales de fermentación, particularmente en la producción industrial de enantiómero(s) distinto(s) de ácido láctico. Además se proporcionan vectores y construcciones útiles para modificar genéticamente a las bacterias que utilizan LA.
MX2018008523A 2016-01-11 2017-01-11 Bacterias que utilizan el acido lactico geneticamente modificadas para secretar enzimas degradantes de los polisacaridos. MX2018008523A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662276985P 2016-01-11 2016-01-11
PCT/IL2017/050031 WO2017122197A1 (en) 2016-01-11 2017-01-11 Lactic acid-utilizing bacteria genetically modified to secrete polysaccharide-degrading enzymes

Publications (1)

Publication Number Publication Date
MX2018008523A true MX2018008523A (es) 2019-05-15

Family

ID=59312037

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018008523A MX2018008523A (es) 2016-01-11 2017-01-11 Bacterias que utilizan el acido lactico geneticamente modificadas para secretar enzimas degradantes de los polisacaridos.

Country Status (9)

Country Link
US (1) US20190169586A1 (es)
EP (1) EP3402872A4 (es)
JP (1) JP2019503688A (es)
CN (1) CN108779434A (es)
AU (1) AU2017208166A1 (es)
CA (1) CA3010562A1 (es)
IL (1) IL260315A (es)
MX (1) MX2018008523A (es)
WO (1) WO2017122197A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA49425A (fr) 2017-06-14 2020-04-22 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN108374030A (zh) * 2018-01-18 2018-08-07 昆明理工大学 一种尖孢镰刀菌胞外多糖的制备方法及应用
RS63273B1 (sr) * 2018-05-11 2022-06-30 4D Pharma Res Ltd Kompozicije koje sadrže bakterijski soj
WO2020208635A1 (en) * 2019-04-10 2020-10-15 3Plw Ltd. Processing organic waste using a highly specific d-lactate oxidase
CN110156174B (zh) * 2019-05-30 2022-01-25 杭州秀川科技有限公司 一种针对高浓高盐制药废水的混合菌种发酵生物预处理方法
FI20195716A1 (en) * 2019-08-30 2021-03-01 Finnfoam Oy Genetically modified fungi and related methods and uses
AU2021222598B2 (en) 2020-02-19 2024-01-04 TripleW Ltd. Methods and systems for lactic acid production and polylactic acid recycling
IL296059B2 (en) * 2020-03-24 2025-07-01 Triplew Ltd Lactic acid production from organic waste using Bacillus coagulans spore cultures
CN111534459B (zh) * 2020-04-14 2021-06-18 华中农业大学 一株高产淀粉酶的发酵乳杆菌及其在制备发酵饲料中的应用
US20230234989A1 (en) * 2020-06-04 2023-07-27 California Institute Of Technology Novel signal peptides generated by attention-based neural networks
CN112094832B (zh) * 2020-09-04 2022-01-18 山东大学 一种突变的耐热耐碱造纸用木聚糖酶及其应用
CN113481117B (zh) * 2021-05-20 2022-07-19 吉林农业大学 一种用于改良苏打盐碱土的多功能菌c1及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE840161L (en) * 1983-01-28 1984-07-28 Nat Ditillers And Chemical Cor GLUCOAMYLASE cDNA
JPH022377A (ja) * 1988-06-08 1990-01-08 Banyu Pharmaceut Co Ltd 放線菌用発現・分泌ベクター用ｄｎａフラグメント
AU4615899A (en) * 1998-06-25 2000-01-10 Dsm N.V. Propionibacterium vector
US7314974B2 (en) * 2002-02-21 2008-01-01 Monsanto Technology, Llc Expression of microbial proteins in plants for production of plants with improved properties
JP5062730B2 (ja) * 2007-02-15 2012-10-31 独立行政法人産業技術総合研究所 改良耐熱性セルラーゼ
EP2861615A1 (en) * 2012-06-04 2015-04-22 Carbios Recombinant cellulosome complex and uses thereof
EP2829274A1 (en) * 2013-07-25 2015-01-28 Institut National De La Recherche Agronomique Vectors for producing and secreting substance of interest by bacteria and applications thereof

Also Published As

Publication number Publication date
WO2017122197A1 (en) 2017-07-20
EP3402872A1 (en) 2018-11-21
CA3010562A1 (en) 2017-07-20
CN108779434A (zh) 2018-11-09
IL260315A (en) 2018-08-30
JP2019503688A (ja) 2019-02-14
EP3402872A4 (en) 2019-06-12
AU2017208166A1 (en) 2018-07-19
US20190169586A1 (en) 2019-06-06

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