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MX2016009771A - Metodos y productos para la produccion y administracion de acido nucleico. - Google Patents

Metodos y productos para la produccion y administracion de acido nucleico.

Info

Publication number
MX2016009771A
MX2016009771A MX2016009771A MX2016009771A MX2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A MX 2016009771 A MX2016009771 A MX 2016009771A
Authority
MX
Mexico
Prior art keywords
methods
nucleic acids
cells
products
proteins
Prior art date
Application number
MX2016009771A
Other languages
English (en)
Other versions
MX372651B (es
Inventor
Angel Matthew
Rohde Christopher
Original Assignee
Factor Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Factor Bioscience Inc filed Critical Factor Bioscience Inc
Publication of MX2016009771A publication Critical patent/MX2016009771A/es
Publication of MX372651B publication Critical patent/MX372651B/es

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    • C07K2319/00Fusion polypeptide
    • C07K2319/80Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor

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Abstract

La presente invención se refiere, en parte, a ácidos nucleicos, inclusive ácidos nucleicos que codifican proteínas, agentes terapéuticos y cosméticos que comprenden ácidos nucleicos, métodos para administrar ácidos nucleicos a células, tejidos, árganos y pacientes, métodos para inducir que las células expresen proteínas mediante el uso de ácidos nucleicos, kits y dispositivos para transfectar, realizar la edición génica y reprogramar células, y células, organismos y agentes terapéuticos y cosméticos producidos mediante el uso de estos métodos, kits y dispositivos. Se describen métodos y productos para alterar la secuencia de ADN de una célula, así como también métodos y productos para inducir que las células expresen proteínas, mediante el uso de moléculas sintéticas de ARN, inclusive células presentes in vivo. También se describen agentes terapéuticos que comprenden ácidos nucleicos que codifican proteínas de edición génica.
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