[go: up one dir, main page]

MX2016005574A - Composiciones de ribosido de nicotinamida para uso topico en el tratamiento de afecciones de la piel. - Google Patents

Composiciones de ribosido de nicotinamida para uso topico en el tratamiento de afecciones de la piel.

Info

Publication number
MX2016005574A
MX2016005574A MX2016005574A MX2016005574A MX2016005574A MX 2016005574 A MX2016005574 A MX 2016005574A MX 2016005574 A MX2016005574 A MX 2016005574A MX 2016005574 A MX2016005574 A MX 2016005574A MX 2016005574 A MX2016005574 A MX 2016005574A
Authority
MX
Mexico
Prior art keywords
nicotinamide riboside
compositions
skin conditions
topical use
treating skin
Prior art date
Application number
MX2016005574A
Other languages
English (en)
Other versions
MX385305B (es
Inventor
Deren-Lewis Ann
RHONEMUS Troy
Original Assignee
Chromadex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chromadex Inc filed Critical Chromadex Inc
Publication of MX2016005574A publication Critical patent/MX2016005574A/es
Publication of MX385305B publication Critical patent/MX385305B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Birds (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)

Abstract

Se proporcionan composiciones se contienen ribósido de nicotinamida (NR). Se utilizan composiciones que contienen NR para el cuidado o tratamiento de la piel y afecciones de la piel. En algunas realizaciones, la invención se refiere a composiciones farmacéuticas y composiciones cosméticas que contienen ribósido de nicotinamida. En realizaciones adicionales, la invención se refiere a métodos para utilizar ribósido de nicotinamida para promover el incremento de los niveles intracelulares del dinucleótido de nicotinamida y adenina (NAD+) en las células y los tejidos para mejorar la supervivencia de las células y los tejidos. Se proporciona un método para tratar las señales o síntomas del envejecimiento o arrugas de la piel en un individuo, que comprende administrar por vía tópica al individuo que necesite un tratamiento de este tipo una cantidad eficaz del compuesto ribosido de nicotinamida o sus sales.
MX2016005574A 2013-10-30 2014-10-30 Composiciones de ribósido de nicotinamida para uso tópico en el tratamiento de afecciones de la piel. MX385305B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361897713P 2013-10-30 2013-10-30
PCT/US2014/063260 WO2015066382A1 (en) 2013-10-30 2014-10-30 Nicotinamide riboside compositions for topical use in treating skin conditions

Publications (2)

Publication Number Publication Date
MX2016005574A true MX2016005574A (es) 2016-12-09
MX385305B MX385305B (es) 2025-03-18

Family

ID=53005146

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016005574A MX385305B (es) 2013-10-30 2014-10-30 Composiciones de ribósido de nicotinamida para uso tópico en el tratamiento de afecciones de la piel.
MX2021009652A MX394291B (es) 2013-10-30 2014-10-30 Composiciones de ribosido de nicotinamida para uso topico en el tratamiento de afecciones de la piel.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021009652A MX394291B (es) 2013-10-30 2014-10-30 Composiciones de ribosido de nicotinamida para uso topico en el tratamiento de afecciones de la piel.

Country Status (12)

Country Link
US (2) US10688118B2 (es)
EP (1) EP3063163B1 (es)
JP (1) JP6509844B2 (es)
KR (3) KR20210107895A (es)
CN (2) CN105873937A (es)
AU (1) AU2014342185B2 (es)
CA (1) CA2928656C (es)
ES (1) ES2925879T3 (es)
MX (2) MX385305B (es)
NZ (1) NZ719328A (es)
WO (1) WO2015066382A1 (es)
ZA (1) ZA201603314B (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2950727A1 (en) * 2014-06-02 2015-12-10 Glaxosmithkline Intellectual Property (No.2) Limited Preparation and use of crystalline beta-d-nicotinamide riboside
MX2016016071A (es) 2014-06-06 2017-07-11 Glaxosmithkline Intellectual Property (No 2) Ltd Analogos de ribosido de nicotinamida y composiciones farmaceuticas y usos de los mismos.
EP3670522B1 (en) 2014-07-24 2022-01-19 W.R. Grace & CO. - CONN. Crystalline form of nicotinamide riboside chloride
US10189872B2 (en) 2015-03-09 2019-01-29 W. R. Grace & Co.-Conn Crystalline form of nicotinamide riboside
CN107531738B (zh) 2015-03-16 2021-02-19 可劳迈戴斯有限公司 烟酸核苷或烟酰胺核苷组合物、其还原衍生物及其用途
WO2016178944A1 (en) 2015-05-01 2016-11-10 The Procter & Gamble Company Method of improving the appearance of skin and compositions therefor using nicotinamide riboside
EP3288531B1 (en) * 2015-05-01 2019-07-24 The Procter and Gamble Company Method of improving skin health and compositions therefor
US20160317420A1 (en) 2015-05-01 2016-11-03 The Procter & Gamble Company Method of improving the appearance of skin and compositions therefor
CN107849083A (zh) * 2015-06-10 2018-03-27 益力舒健康公司 用于治疗皮肤病症的烟酰胺核苷和紫檀芪组合物和方法
WO2016210232A1 (en) * 2015-06-25 2016-12-29 N.V. Perricone Llc Niacinamide mononucleotide formulations for skin aging
US20160374918A1 (en) * 2015-06-29 2016-12-29 The Procter & Gamble Company Encapsulated skin care agent
WO2017004102A1 (en) 2015-06-29 2017-01-05 The Procter & Gamble Company Multi-component skin care product comprising nicoinamide riboside in a multi-chambered container
US20160374908A1 (en) 2015-06-29 2016-12-29 The Procter & Gamble Company Skin care composition and methods of using the same
BR112018013757B1 (pt) 2016-01-11 2021-11-09 The Procter & Gamble Company Método para o tratamento de uma condição de pele e composições para o mesmo
WO2017161165A1 (en) 2016-03-16 2017-09-21 ChromaDex Inc. B-vitamin and amino acid conjugates of nicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof
AU2017254657A1 (en) * 2016-04-20 2018-11-15 ChromaDex Inc. Use of Nicotinic acid Riboside or Nicotinamide Ribosite derivatives, and reduced derivatives thereof, as nad+increasing precursors
CN109982706A (zh) * 2016-08-22 2019-07-05 益力舒健康公司 用于治疗神经退行性病症的烟酰胺核苷和紫檀芪的组合物和方法
NZ803738A (en) 2016-11-11 2024-05-31 Chromadex Inc Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof
MX2019006278A (es) 2016-11-29 2019-08-21 Univ Iowa Res Found Uso de precursores de nad para mejorar la salud materna y/o salud de la descendencia.
US11071747B2 (en) 2016-11-29 2021-07-27 University Of Iowa Research Foundation Use of NAD precursors for breast enhancement
CN110099672B (zh) 2016-12-21 2022-05-24 联合利华知识产权控股有限公司 具有氨基酸和烟酰胺化合物的局部皮肤增亮添加剂和组合物
CN110121330B (zh) 2016-12-21 2022-04-29 联合利华知识产权控股有限公司 具有包含4-取代的间苯二酚和氨基酸的谷胱甘肽前体的个人护理组合物
US10751267B2 (en) 2016-12-21 2020-08-25 Conopco, Inc. Personal care compositions comprising poorly soluble compounds
CA3047215A1 (en) 2016-12-21 2018-06-28 Unilever Plc Personal care compositions with cystine
RU2651047C1 (ru) * 2017-05-04 2018-04-18 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Лекарственная композиция цитопротекторного действия и способ ее получения
CN111093676A (zh) * 2017-05-18 2020-05-01 益力舒健康公司 改善睡眠的方法和组合物
WO2018236814A2 (en) 2017-06-19 2018-12-27 Gangadhara Ganapati Nicotinamide riboside derivatives and their uses
CN110785161B (zh) 2017-06-23 2023-06-20 宝洁公司 用于改善皮肤外观的组合物和方法
CN111542312A (zh) 2017-07-28 2020-08-14 老龄化控制中心股份公司 预防和逆转衰老方面的组合物和方法
CN111093397A (zh) * 2017-09-14 2020-05-01 田中惠 一种抗衰老剂以及抗衰老方法
GB201716391D0 (en) * 2017-10-06 2017-11-22 Xobaderm Ltd Kit for delivery of an active compound into a biological barrier
US11414407B2 (en) 2017-12-22 2022-08-16 Elysium Health, Inc. Crystalline forms of nicotinamide riboside chloride
KR20210011964A (ko) 2018-07-03 2021-02-02 더 프록터 앤드 갬블 캄파니 피부 병태를 치료하는 방법
JP6887025B2 (ja) * 2018-08-17 2021-06-16 邦泰生物工程（深▲セン▼）有限公司 安定型ニコチンアミドリボシド組成物及びその調製方法
KR102060374B1 (ko) * 2018-12-14 2019-12-30 주식회사 휴메딕스 지방알코올 컨쥬게이션된 니코틴아미드 리보사이드 유도체
US11833167B2 (en) 2018-12-17 2023-12-05 Mitopower Llc Nicotinyl riboside compounds and their uses
EP4471043A3 (en) 2019-07-19 2025-03-05 Biosynth AG Method of making nicotinamide ribofuranoside salts, nicotinamide ribofuranoside salts as such, and uses thereof
CN110638827A (zh) * 2019-10-17 2020-01-03 泓博元生命科技（深圳）有限公司 Nadh及其盐在制备皮肤色素抑制剂中的应用
CN111166760A (zh) * 2019-12-17 2020-05-19 浙江安赛新材料科技有限公司 β-烟酰胺单核苷酸或其前体的组合物及制备方法、应用
KR102315139B1 (ko) 2019-12-17 2021-10-20 주식회사 휴메딕스 지방아민 컨쥬게이션된 니코틴아미드 리보사이드 유도체
CN111184732B (zh) * 2020-03-04 2023-09-08 武汉华纳联合药业有限公司 一种复合组合物制剂及其制备方法和皮肤炎症中的应用
CN111454311B (zh) * 2020-04-03 2021-10-19 深圳市迪克曼科技开发有限公司 烟酰胺核糖的有机酸盐及其组合物与制备方法
EP4153323A1 (fr) * 2020-05-20 2023-03-29 Nuvamid SA Compositions cosmetiques anti-age comprenant du nmn
FR3110410A1 (fr) * 2020-05-20 2021-11-26 Nuvamid Sa Compositions cosmétiques anti-âge comprenant de la NMN
WO2021247496A1 (en) 2020-06-01 2021-12-09 The Procter & Gamble Company Method of improving penetration of a vitamin b3 compound into skin
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
CN111632049A (zh) * 2020-06-09 2020-09-08 西北农林科技大学 一种通过综合矫正细胞活性氧簇代谢紊乱以缓解睾丸衰老损伤的复合配方
US20230263817A1 (en) * 2020-08-28 2023-08-24 University Of Washington High dose nicotinamide adenine dinucleotide (nad) precursor regimens for reduction of inflammation in human patients with preexisting inflammation
EP4281465A1 (en) * 2021-01-19 2023-11-29 Biosynth AG Method of making nicotinamide ribofuranoside salts by salt metathesis, the crystalline form of its tosylate salt and the co-crystallized form of its chloride:iodide salt
US20220354879A1 (en) * 2021-05-04 2022-11-10 Sovida Solutions Ltd. Nicotinamide adenine dinucleotide (nad) compositions, methods of manufacturing thereof, and methods of use thereof
CN114129509B (zh) * 2021-12-03 2023-12-01 药酚享科技(北京)有限公司 一种保湿性nmn亲水凝胶剂及其制备方法
CN114933621A (zh) * 2022-04-13 2022-08-23 深圳市迪克曼生物科技有限公司 烟酰胺核糖的有机酸盐及其结晶形态、制备方法与用途
KR102784901B1 (ko) * 2022-06-23 2025-03-21 제너럴바이오(주) Nr, nmn 및 nad를 함유한 피부 주름 개선용 화장료 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002253018A1 (en) * 2001-02-22 2002-09-12 Unilever Plc Skin composition for reducing skin oils and grease
US7977049B2 (en) 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
JP2007521835A (ja) 2004-02-10 2007-08-09 トラスティーズ・オブ・ダートマウス・カレッジ ニコチンアミドリボシドキナーゼ組成物およびそれらの使用方法
US7776326B2 (en) 2004-06-04 2010-08-17 Washington University Methods and compositions for treating neuropathies
WO2006105440A2 (en) 2005-03-30 2006-10-05 Sirtris Pharmaceuticals, Inc. Nicotinamide riboside and analogues thereof
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
JP2009500357A (ja) * 2005-07-07 2009-01-08 サートリス ファーマシューティカルズ， インコーポレイテッド 肥満、インスリン抵抗性障害およびミトコンドリア関連障害を処置または予防するための方法および関連する組成物
CN101257897A (zh) * 2005-07-07 2008-09-03 西特里斯药业公司 用于治疗或预防肥胖、胰岛素抵抗障碍和线粒体相关障碍的方法和相关组合物
WO2007061798A2 (en) 2005-11-18 2007-05-31 Cornell Research Foundation, Inc. Nicotinoyl riboside compositions and methods of use
KR101500020B1 (ko) * 2007-03-12 2015-03-06 디에스엠 아이피 어셋츠 비.브이. 미용 조성물
US20090069444A1 (en) 2007-09-07 2009-03-12 The United States Of America, As Represented By Th E Secretary Of Agriculture Method to Ameliorate Oxidative Stress and Improve Working Memory Via Pterostilbene Administration
KR101807328B1 (ko) * 2010-01-06 2017-12-08 가부시키가이샤 야쿠르트 혼샤 경구용 ｄｎａ 손상 수복 촉진제 및 엘라스타아제 활성 억제제

Also Published As

Publication number Publication date
MX394291B (es) 2025-03-24
EP3063163A4 (en) 2017-05-10
KR20160067195A (ko) 2016-06-13
ZA201603314B (en) 2017-09-27
EP3063163A1 (en) 2016-09-07
KR20220098049A (ko) 2022-07-08
AU2014342185B2 (en) 2019-01-03
JP6509844B2 (ja) 2019-05-08
ES2925879T3 (es) 2022-10-20
US11033568B2 (en) 2021-06-15
US10688118B2 (en) 2020-06-23
MX385305B (es) 2025-03-18
CN109985056A (zh) 2019-07-09
NZ719328A (en) 2022-04-29
CN105873937A (zh) 2016-08-17
KR20210107895A (ko) 2021-09-01
MX2021009652A (es) 2022-07-26
WO2015066382A1 (en) 2015-05-07
US20200289536A1 (en) 2020-09-17
CA2928656A1 (en) 2015-05-07
JP2016538271A (ja) 2016-12-08
EP3063163B1 (en) 2022-08-10
US20160250241A1 (en) 2016-09-01
CA2928656C (en) 2020-07-28

Similar Documents

Publication Publication Date Title
MX2016005574A (es) Composiciones de ribosido de nicotinamida para uso topico en el tratamiento de afecciones de la piel.
MX2017011851A (es) Composiciones de acido nicotinico ribosido o de nicotinamida ribosido, derivados reducidos de los mismos, y su uso.
MX2019002750A (es) Derivados de pirazolopiridina como moduladores de cinasa 1 progenitora hematopoyetica (hpk1) y usos de los mismos para tratamiento de cancer.
MX394252B (es) Tratamiento del cancer usando combinaciones de inhibidores de erk y raf
PE20150223A1 (es) Anticuerpos antagonistas mejorados contra factor-8 de crecimiento y diferenciacion y usos de los mismos
BR112014006455A2 (pt) alquilamidotiazóis, preparações cosméticas ou dermatológicas com um teor de um ou vários alquilamidotiazóis e uso de um ou vários alquilamidotiazóis
SV2016005320A (es) Formulaciones y mã‰todos de tratamiento con queratina
CO2017001493A2 (es) Kits que comprenden inhibidores tigit y agentes anticáncer
UY35427A (es) Compuestos y sus usos en la modulación de la hemoglobina
UY35425A (es) Compuestos y sus usos en la modulación de la hemoglobina
UY35426A (es) Compuestos y sus usos en la modulación de la hemoglobina
PE20121520A1 (es) Formulacion farmaceutica que comprende ranolazina y dronedarona en el tratamiento de fibrilacion auricular
ECSP13012417A (es) Derivados de ácido napht-2-ilacético para tratar sida
CL2016000544A1 (es) Composición cosmética que comprende 0,0001 a 10% en peso de extracto de guacatonga (casearia sylvestris) y 0,00005 a 10% en peso de extracto de aroeira (schinus terebinthifolius raddi) ambos respecto al peso total de la composición; uso de la composición en la prevención y/o tratamiento de los signos de envejicimiento de la piel; metodo para prevenir y/o tratar los signos de envejecimiento de la piel.
MX2017016024A (es) Composiciones de nicotinamida ribósido y pteroestilbeno y métodos para el tratamiento de trastornos de la piel.
AR075442A1 (es) Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
AR092899A1 (es) Uso de masitinib para el tratamiento del cancer en subpoblaciones de pacientes identificados que utilizan factores de prediccion
MX2017014245A (es) Composiciones que comprenden celulas germinales mesenquimales y usos de las mismas.
BR112014003071A2 (pt) tratamento de doença vascular periférica com o uso de células derivadas do tecido do cordão umbilical
CL2020000019A1 (es) Agentes de iarn para la inhibición de la expresión de alfa-enac y métodos de uso.
MX2022005450A (es) Composiciones que contienen cannabidiol (cbd) de accion periferica y usos de las mismas para mejorar la funcion sexual femenina o tratar trastornos sexuales femeninos.
UY33790A (es) Composiciones y métodos para tratar el cáncer usando un inhibidor de pi3k e inhibidor de mek.
AR087902A1 (es) COMPOSICIONES Y METODOS PARA TRATAR EL CANCER USANDO EL INHIBIDOR DE PI3Kb Y EL INHIBIDOR DE LA VIA DE MAPK, INCLUIDOS LOS INHIBIDORES DE MEK Y RAF
CR20110226A (es) Composición para tratar enfermedad
PE20181450A1 (es) Compuestos de 1,3,4-tiadiazol y su uso en el tratamiento del cancer