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MX2016002651A - Microorganismo modificado para la produccion mejorada de alanina. - Google Patents

Microorganismo modificado para la produccion mejorada de alanina.

Info

Publication number
MX2016002651A
MX2016002651A MX2016002651A MX2016002651A MX2016002651A MX 2016002651 A MX2016002651 A MX 2016002651A MX 2016002651 A MX2016002651 A MX 2016002651A MX 2016002651 A MX2016002651 A MX 2016002651A MX 2016002651 A MX2016002651 A MX 2016002651A
Authority
MX
Mexico
Prior art keywords
alanine
modified microorganism
improved production
modified
microorganism
Prior art date
Application number
MX2016002651A
Other languages
English (en)
Inventor
Schröder Hartwig
Zelder Oskar
Martyna KRAWCZYK Joanna
Haefner Stefan
Thomas Fabarius Jonathan
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of MX2016002651A publication Critical patent/MX2016002651A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
    • C12Y104/01001—Alanine dehydrogenase (1.4.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)

Abstract

La presente invención se refiere a un microorganismo modificado que presenta, en comparación con su tipo salvaje, una actividad incrementada de la enzima que está codificada por el gen alaD. La presente invención también se refiere a un método para producir una alanina y al uso de microorganismos modificados.
MX2016002651A 2013-08-30 2014-08-18 Microorganismo modificado para la produccion mejorada de alanina. MX2016002651A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13182425 2013-08-30
PCT/IB2014/063950 WO2015028915A1 (en) 2013-08-30 2014-08-18 Modified microorganism for improved production of alanine

Publications (1)

Publication Number Publication Date
MX2016002651A true MX2016002651A (es) 2016-09-23

Family

ID=49036529

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016002651A MX2016002651A (es) 2013-08-30 2014-08-18 Microorganismo modificado para la produccion mejorada de alanina.

Country Status (10)

Country Link
US (1) US20160304917A1 (es)
EP (1) EP3039121A4 (es)
JP (1) JP2016529901A (es)
KR (1) KR20160043973A (es)
CN (1) CN105593361A (es)
BR (1) BR112016002105A2 (es)
CA (1) CA2920814A1 (es)
MX (1) MX2016002651A (es)
RU (1) RU2016111682A (es)
WO (1) WO2015028915A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3052630A4 (en) 2013-09-25 2017-08-16 Basf Se Recombinant microorganism for improved production of fine chemicals
US10208324B2 (en) 2013-12-13 2019-02-19 Basf Se Recombinant microorganism for improved production of fine chemicals
MX389370B (es) 2015-06-04 2025-03-20 Basf Se Microorganismo recombinante para la produccion mejorada de quimicos finos.
KR20180011324A (ko) 2015-06-12 2018-01-31 바스프 에스이 알라닌의 개선된 제조를 위한 재조합 미생물
CN107937361B (zh) * 2018-01-15 2019-02-12 金华利家园生物工程有限公司 一种丙氨酸脱氢酶突变体及其应用
CN110305823B (zh) * 2018-11-16 2021-05-04 江南大学 采用乳酸生产l-丙氨酸的方法及菌株
EP3960879A1 (en) * 2020-09-01 2022-03-02 Metabolic Explorer Microorganism and method for the improved production of alanine
KR20240108883A (ko) * 2022-12-30 2024-07-10 씨제이제일제당 (주) 신규한 폴리뉴클레오티드 및 이를 이용한 l-알라닌 생산 방법
CN119842584A (zh) * 2025-01-21 2025-04-18 浙江工业大学 一种以隐秘质粒为表达载体的高产β-丙氨酸的工程菌及双碳源发酵方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008119009A2 (en) * 2007-03-27 2008-10-02 University Of Florida Research Foundation, Inc. Materials and methods for efficient alanine production
KR101575912B1 (ko) * 2007-08-17 2015-12-08 바스프 에스이 파스테우렐라세애의 카복실산 생산 구성원
EP3505619A1 (en) * 2009-02-16 2019-07-03 Basf Se Novel microbial succinic acid producers and purification of succinic acid
CN101974476A (zh) * 2010-08-31 2011-02-16 安徽华恒生物工程有限公司 一种高产l-丙氨酸的xz-a26菌株及构建方法与应用
CN103045528B (zh) * 2012-12-28 2014-05-07 安徽华恒生物工程有限公司 生产dl-丙氨酸的工程菌及利用该工程菌生产dl-丙氨酸的方法

Also Published As

Publication number Publication date
EP3039121A1 (en) 2016-07-06
WO2015028915A1 (en) 2015-03-05
RU2016111682A (ru) 2017-10-05
BR112016002105A2 (pt) 2017-08-29
CA2920814A1 (en) 2015-03-05
CN105593361A (zh) 2016-05-18
JP2016529901A (ja) 2016-09-29
EP3039121A4 (en) 2017-05-03
US20160304917A1 (en) 2016-10-20
KR20160043973A (ko) 2016-04-22

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