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MX2014008773A - Composiciones y metodos para el uso de ésteres de forbol. - Google Patents

Composiciones y metodos para el uso de ésteres de forbol.

Info

Publication number
MX2014008773A
MX2014008773A MX2014008773A MX2014008773A MX2014008773A MX 2014008773 A MX2014008773 A MX 2014008773A MX 2014008773 A MX2014008773 A MX 2014008773A MX 2014008773 A MX2014008773 A MX 2014008773A MX 2014008773 A MX2014008773 A MX 2014008773A
Authority
MX
Mexico
Prior art keywords
diseases
methods
forbol
chronic
compositions
Prior art date
Application number
MX2014008773A
Other languages
English (en)
Other versions
MX373291B (es
Inventor
Hung-Fong Chen
Zeng Tao Han
Original Assignee
Biosuccess Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosuccess Biotech Co Ltd filed Critical Biosuccess Biotech Co Ltd
Publication of MX2014008773A publication Critical patent/MX2014008773A/es
Publication of MX373291B publication Critical patent/MX373291B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/33Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with hydroxy compounds having more than three hydroxy groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
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    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • C07C2603/40Ortho- or ortho- and peri-condensed systems containing four condensed rings

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Abstract

Métodos y composiciones que contienen ésteres de forbol o un derivado de un éster de forbol se provee para el tratamiento de enfermedades crónicas y agudas. Dichas condiciones pueden ser causadas por enfermedad, por síntomas o secuelas de la enfermedad. Enfermedades crónicas y agudas pueden deberse a infecciones virales como el VIH y el SIDA, enfermedades neoplásicas por infarto cerebral, enfermedades del riñón, incontinencia urinaria, desordenes autoinmunes, enfermedad de Parkinson, hipertrofia de la próstata, el envejecimiento, o el tratamiento de dichas enfermedades. Adicionalmente se proveen composiciones y métodos los cuales emplean ésteres de forbol o compuestos derivados en combinación con al menos un agente adicional para producir herramientas de tratamiento más eficaces contra las condiciones agudas y crónicas en sujetos mamíferos.
MX2014008773A 2012-01-18 2013-01-18 Composiciones y metodos para el uso de ésteres de forbol MX373291B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261588162P 2012-01-18 2012-01-18
US201261588167P 2012-01-18 2012-01-18
US201261588165P 2012-01-18 2012-01-18
PCT/US2013/022324 WO2013110006A2 (en) 2012-01-18 2013-01-18 Compositions and methods of use of phorbol esters

Publications (2)

Publication Number Publication Date
MX2014008773A true MX2014008773A (es) 2015-04-10
MX373291B MX373291B (es) 2020-05-06

Family

ID=48799818

Family Applications (4)

Application Number Title Priority Date Filing Date
MX2019011333A MX389510B (es) 2012-01-18 2013-01-18 Composiciones y métodos para el uso de ésteres de forbol para el tratamiento de accidentes cerebrovasculares.
MX2018000468A MX395719B (es) 2012-01-18 2013-01-18 Composiciones y métodos para el uso de ésteres de forbol.
MX2014008776A MX370146B (es) 2012-01-18 2013-01-18 Composiciones y métodos para uso de ésteres de forbol para el tratamiento de accidentes cerebrovasculares.
MX2014008773A MX373291B (es) 2012-01-18 2013-01-18 Composiciones y metodos para el uso de ésteres de forbol

Family Applications Before (3)

Application Number Title Priority Date Filing Date
MX2019011333A MX389510B (es) 2012-01-18 2013-01-18 Composiciones y métodos para el uso de ésteres de forbol para el tratamiento de accidentes cerebrovasculares.
MX2018000468A MX395719B (es) 2012-01-18 2013-01-18 Composiciones y métodos para el uso de ésteres de forbol.
MX2014008776A MX370146B (es) 2012-01-18 2013-01-18 Composiciones y métodos para uso de ésteres de forbol para el tratamiento de accidentes cerebrovasculares.

Country Status (18)

Country Link
US (1) US20170096386A1 (es)
EP (2) EP2804669B1 (es)
JP (5) JP6336914B2 (es)
KR (4) KR102102640B1 (es)
CN (4) CN104507466A (es)
AU (7) AU2013287280B2 (es)
BR (2) BR112014017650B1 (es)
CA (3) CA2861459C (es)
IL (2) IL233674B (es)
MX (4) MX389510B (es)
MY (5) MY176593A (es)
NZ (4) NZ726666A (es)
PH (10) PH12014501656B1 (es)
RU (3) RU2659684C2 (es)
SG (12) SG10201912642RA (es)
TW (6) TW201350111A (es)
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