MX2014001373A - Composicion farmaceutica para el tratamiento y/o prevencion del cancer. - Google Patents
Composicion farmaceutica para el tratamiento y/o prevencion del cancer.Info
- Publication number
- MX2014001373A MX2014001373A MX2014001373A MX2014001373A MX2014001373A MX 2014001373 A MX2014001373 A MX 2014001373A MX 2014001373 A MX2014001373 A MX 2014001373A MX 2014001373 A MX2014001373 A MX 2014001373A MX 2014001373 A MX2014001373 A MX 2014001373A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody
- prevention
- cancer treatment
- drug composition
- cancer
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 201000011510 cancer Diseases 0.000 title abstract 5
- 230000002265 prevention Effects 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 108010047041 Complementarity Determining Regions Proteins 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 102100029949 Caprin-1 Human genes 0.000 abstract 1
- 101710072528 Caprin-1 Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000009257 reactivity Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Esta invención proporciona un anticuerpo que se dirige a una proteína antigénica del cáncer, específicamente expresada sobre la superficie de las células cancerosas, y el uso del mismo como un agente terapéutico y/o preventivo para el cáncer. Más específicamente, la presente invención proporciona un anticuerpo o un fragmento el mismo que tiene reactividad inmunológica con una proteína CAPRIN-1, el anticuerpo comprende una región variable de cadena pesada que comprende las regiones de determinación de la complementariedad de las SEQ ID NOs: 5, 6, 7 y una región variable de cadena ligera que comprende las regiones de determinación de la complementariedad de las SEQ ID NOs: 9, 10 y 11 y una composición farmacéutica para el tratamiento y/o prevención del cáncer, que comprende el mismo como un ingrediente activo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011171332 | 2011-08-04 | ||
| PCT/JP2012/069857 WO2013018892A1 (ja) | 2011-08-04 | 2012-08-03 | 癌の治療及び／又は予防用医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014001373A true MX2014001373A (es) | 2014-05-21 |
| MX348579B MX348579B (es) | 2017-06-20 |
Family
ID=47629406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014001373A MX348579B (es) | 2011-08-04 | 2012-08-03 | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9181334B2 (es) |
| EP (1) | EP2740793B1 (es) |
| JP (1) | JP6015448B2 (es) |
| KR (1) | KR101968498B1 (es) |
| CN (1) | CN103717738B (es) |
| AU (1) | AU2012290955B2 (es) |
| BR (1) | BR112014002621B1 (es) |
| CA (1) | CA2844038C (es) |
| DK (1) | DK2740793T3 (es) |
| ES (1) | ES2660115T3 (es) |
| HU (1) | HUE035689T2 (es) |
| MX (1) | MX348579B (es) |
| PL (1) | PL2740793T3 (es) |
| PT (1) | PT2740793T (es) |
| RU (1) | RU2624049C2 (es) |
| TR (1) | TR201802089T4 (es) |
| WO (1) | WO2013018892A1 (es) |
Families Citing this family (62)
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| RU2498819C2 (ru) | 2008-08-05 | 2013-11-20 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и профилактики злокачественных опухолей |
| EP2532743B1 (en) * | 2010-02-04 | 2015-04-15 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| WO2013018886A1 (ja) * | 2011-08-04 | 2013-02-07 | 東レ株式会社 | 膵臓癌の治療及び／又は予防用医薬組成物 |
| US9796775B2 (en) * | 2011-08-04 | 2017-10-24 | Toray Industries, Inc. | Method for detecting pancreatic cancer |
| US12466897B2 (en) | 2011-10-10 | 2025-11-11 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| PT2818483T (pt) | 2012-02-21 | 2017-10-09 | Toray Industries | Composição medicinal para tratamento e/ou prevenção de cancro |
| HUE036425T2 (hu) | 2012-03-30 | 2018-07-30 | Toray Industries | Gyógyászati készítmény epehólyagrák kezelésére és/vagy megelõzésére |
| PL2832365T3 (pl) * | 2012-03-30 | 2018-04-30 | Toray Industries, Inc. | Kompozycja farmaceutyczna do leczenia i/lub zapobiegania nowotworowi wątroby |
| US9772332B2 (en) | 2012-07-19 | 2017-09-26 | Toray Industries, Inc. | Method for detecting CAPRIN-1 in a biological sample |
| RU2646464C2 (ru) | 2012-07-19 | 2018-03-05 | Торэй Индастриз, Инк. | Метод детекции рака |
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2012
- 2012-08-03 PT PT128197597T patent/PT2740793T/pt unknown
- 2012-08-03 HU HUE12819759A patent/HUE035689T2/en unknown
- 2012-08-03 PL PL12819759T patent/PL2740793T3/pl unknown
- 2012-08-03 KR KR1020147005882A patent/KR101968498B1/ko active Active
- 2012-08-03 EP EP12819759.7A patent/EP2740793B1/en active Active
- 2012-08-03 BR BR112014002621-1A patent/BR112014002621B1/pt active IP Right Grant
- 2012-08-03 ES ES12819759.7T patent/ES2660115T3/es active Active
- 2012-08-03 WO PCT/JP2012/069857 patent/WO2013018892A1/ja not_active Ceased
- 2012-08-03 AU AU2012290955A patent/AU2012290955B2/en active Active
- 2012-08-03 JP JP2012543825A patent/JP6015448B2/ja active Active
- 2012-08-03 US US14/236,812 patent/US9181334B2/en active Active
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- 2012-08-03 MX MX2014001373A patent/MX348579B/es active IP Right Grant
- 2012-08-03 TR TR2018/02089T patent/TR201802089T4/tr unknown
- 2012-08-03 CA CA2844038A patent/CA2844038C/en active Active
- 2012-08-03 DK DK12819759.7T patent/DK2740793T3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103717738A (zh) | 2014-04-09 |
| CA2844038A1 (en) | 2013-02-07 |
| DK2740793T3 (en) | 2018-01-22 |
| RU2014108042A (ru) | 2015-09-10 |
| KR101968498B1 (ko) | 2019-04-12 |
| PL2740793T3 (pl) | 2018-04-30 |
| JPWO2013018892A1 (ja) | 2015-03-05 |
| CN103717738B (zh) | 2015-07-15 |
| EP2740793A4 (en) | 2015-04-01 |
| AU2012290955A1 (en) | 2014-03-20 |
| WO2013018892A1 (ja) | 2013-02-07 |
| KR20140054186A (ko) | 2014-05-08 |
| RU2624049C2 (ru) | 2017-06-30 |
| US9181334B2 (en) | 2015-11-10 |
| CA2844038C (en) | 2019-05-07 |
| AU2012290955B2 (en) | 2017-04-27 |
| BR112014002621A2 (pt) | 2017-12-12 |
| JP6015448B2 (ja) | 2016-10-26 |
| US20140199311A1 (en) | 2014-07-17 |
| MX348579B (es) | 2017-06-20 |
| BR112014002621B1 (pt) | 2022-09-20 |
| TR201802089T4 (tr) | 2018-03-21 |
| PT2740793T (pt) | 2018-02-23 |
| ES2660115T3 (es) | 2018-03-20 |
| EP2740793B1 (en) | 2017-11-29 |
| EP2740793A1 (en) | 2014-06-11 |
| HUE035689T2 (en) | 2018-05-28 |
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