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MX2012013710A - Peptidos de union al receptor del factor 1 de crecimiento similar a la insulina. - Google Patents

Peptidos de union al receptor del factor 1 de crecimiento similar a la insulina.

Info

Publication number
MX2012013710A
MX2012013710A MX2012013710A MX2012013710A MX2012013710A MX 2012013710 A MX2012013710 A MX 2012013710A MX 2012013710 A MX2012013710 A MX 2012013710A MX 2012013710 A MX2012013710 A MX 2012013710A MX 2012013710 A MX2012013710 A MX 2012013710A
Authority
MX
Mexico
Prior art keywords
insulin
growth factor
polypeptides
receptor binding
disclosed
Prior art date
Application number
MX2012013710A
Other languages
English (en)
Other versions
MX337134B (es
Inventor
Karyn O'neil
Michael Diem
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MX2012013710A publication Critical patent/MX2012013710A/es
Publication of MX337134B publication Critical patent/MX337134B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describen polipéptidos de unión al receptor del factor 1 de crecimiento similar a la insulina, y los polinucleótidos que codifican el polipéptido; se describen, además, los métodos para producir los polipéptidos por medio del uso de sistemas de expresión de células y sistemas libres de célula, y métodos para usar los polipéptidos para la producción de proteínas de fusión; los polipéptidos descritos pueden proporcionar medios para suministrar agentes terapéuticos a través de la barrera hematoencefálica (BBB).
MX2012013710A 2010-05-27 2011-05-25 Peptidos de union al receptor del factor 1 de crecimiento similar a la insulina. MX337134B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34893710P 2010-05-27 2010-05-27
PCT/US2011/037904 WO2011150061A1 (en) 2010-05-27 2011-05-25 Insulin-like growth factor 1 receptor binding peptides

Publications (2)

Publication Number Publication Date
MX2012013710A true MX2012013710A (es) 2013-05-20
MX337134B MX337134B (es) 2016-02-12

Family

ID=45004356

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012013710A MX337134B (es) 2010-05-27 2011-05-25 Peptidos de union al receptor del factor 1 de crecimiento similar a la insulina.

Country Status (27)

Country Link
US (1) US8415306B2 (es)
EP (1) EP2575846B1 (es)
JP (1) JP5864556B2 (es)
KR (1) KR101898502B1 (es)
CN (1) CN103025341B (es)
AU (1) AU2011258301B2 (es)
BR (1) BR112012030084B1 (es)
CA (1) CA2800744C (es)
CY (1) CY1116757T1 (es)
DK (1) DK2575846T3 (es)
EA (1) EA023541B1 (es)
ES (1) ES2550040T3 (es)
HR (1) HRP20151084T1 (es)
HU (1) HUE026269T2 (es)
IL (1) IL223030A (es)
ME (1) ME02206B (es)
MX (1) MX337134B (es)
NZ (1) NZ603611A (es)
PL (1) PL2575846T3 (es)
PT (1) PT2575846E (es)
RS (1) RS54278B1 (es)
SG (1) SG186068A1 (es)
SI (1) SI2575846T1 (es)
SM (1) SMT201500222B (es)
UA (1) UA107596C2 (es)
WO (1) WO2011150061A1 (es)
ZA (1) ZA201209689B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA120047C2 (uk) * 2014-03-06 2019-09-25 Нешнл Рісеч Каунсіл Оф Канада Антигензв'язуючий фрагмент антитіла, який специфічно зв'язується з рецептором інсуліноподібного фактора росту 1 (igf1r)
PE20170088A1 (es) * 2014-03-06 2017-03-09 Nat Res Council Canada Anticuerpos especificos del receptor del factor 1 de crecimiento similar a la insulina y usos de los mismos
MX2016011561A (es) * 2014-03-06 2017-04-13 Nat Res Council Canada Anticuerpos especificos para el receptor del factor de crecimiento similar a insulina 1 y usos de los mismos.
RU2694064C1 (ru) 2015-12-21 2019-07-09 Браинон Инк. Композиция для улучшения памяти, способности к обучению и когнитивных способностей
KR101706296B1 (ko) 2015-12-21 2017-02-13 주식회사 브레인온 기억력, 학습력, 인지력 향상용 조성물

Family Cites Families (20)

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US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US6329508B1 (en) 1989-09-07 2001-12-11 Alkermes, Inc. Transferrin receptor reactive chimeric antibodies
JPH06228199A (ja) * 1992-11-27 1994-08-16 Takeda Chem Ind Ltd 血液脳関門通過可能なペプチド結合体
EP1006184A1 (en) * 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
US20100293669A2 (en) 1999-05-06 2010-11-18 Jingdong Liu Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
US20090087878A9 (en) 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants
AU6607100A (en) 1999-07-23 2001-02-13 Regents Of The University Of California, The Anti-growth factor receptor avidin fusion proteins as universal vectors for drugdelivery
EP1221975B1 (en) 1999-10-04 2006-12-06 Nektar Therapeutics Al, Corporation Polymer stabilized neuropeptides
US20020009491A1 (en) 2000-02-14 2002-01-24 Rothbard Jonathan B. Compositions and methods for enhancing drug delivery across biological membranes and tissues
WO2002026781A2 (en) * 2000-09-26 2002-04-04 Genentech, Inc. Ige receptor antagonists
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
EP1494712A4 (en) * 2002-03-26 2006-06-14 Centocor Inc MULTIPLE SCLEROSIS RELATED PROTEINS, COMPOSITIONS, PROCESSES AND APPLICATIONS DERIVED FROM IMMUNOGLOBULIN
US7388079B2 (en) * 2002-11-27 2008-06-17 The Regents Of The University Of California Delivery of pharmaceutical agents via the human insulin receptor
US20050026823A1 (en) 2003-06-20 2005-02-03 Biomarin Pharmaceutical Inc. Use of the chaperone receptor-associated protein (RAP) for the delivery of therapeutic compounds to the brain and other tissues
US8017151B2 (en) 2004-09-07 2011-09-13 Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center Amphiphilic polymer-protein conjugates and methods of use thereof
MX2007016306A (es) * 2005-06-15 2008-03-07 Schering Corp Formulaciones de anticuerpo anti-igf1r.
US8142781B2 (en) * 2005-10-07 2012-03-27 Armagen Technologies, Inc. Fusion proteins for blood-brain barrier delivery
WO2008143679A2 (en) * 2006-06-01 2008-11-27 Verenium Corporation Nucleic acids and proteins and methods for making and using them
CN101842116A (zh) * 2007-08-28 2010-09-22 比奥根艾迪克Ma公司 结合igf-1r多个表位的组合物
ES2564523T3 (es) 2007-12-19 2016-03-23 Janssen Biotech, Inc. Diseño y generación de bibliotecas de presentación en fago por pIX de novo humanas mediante fusión con pIX o pVII, vectores, anticuerpos y métodos

Also Published As

Publication number Publication date
HUE026269T2 (en) 2016-06-28
HK1183234A1 (zh) 2013-12-20
KR101898502B1 (ko) 2018-09-13
SMT201500222B (it) 2015-10-30
CA2800744A1 (en) 2011-12-01
EA023541B1 (ru) 2016-06-30
EP2575846A4 (en) 2013-12-11
UA107596C2 (uk) 2015-01-26
HRP20151084T1 (hr) 2015-11-06
CN103025341B (zh) 2015-07-22
JP5864556B2 (ja) 2016-02-17
ZA201209689B (en) 2014-05-28
IL223030A (en) 2016-11-30
CY1116757T1 (el) 2017-03-15
MX337134B (es) 2016-02-12
CN103025341A (zh) 2013-04-03
RS54278B1 (sr) 2016-02-29
IL223030A0 (en) 2013-02-03
SG186068A1 (en) 2013-01-30
ME02206B (me) 2016-02-20
AU2011258301A1 (en) 2012-12-06
KR20130111237A (ko) 2013-10-10
PL2575846T3 (pl) 2015-12-31
BR112012030084B1 (pt) 2020-04-14
EP2575846B1 (en) 2015-07-15
PT2575846E (pt) 2015-09-16
CA2800744C (en) 2018-09-04
JP2013534811A (ja) 2013-09-09
NZ603611A (en) 2014-12-24
EP2575846A1 (en) 2013-04-10
BR112012030084A2 (pt) 2017-06-20
US8415306B2 (en) 2013-04-09
ES2550040T3 (es) 2015-11-04
SI2575846T1 (sl) 2015-09-30
US20110294748A1 (en) 2011-12-01
AU2011258301B2 (en) 2013-11-21
WO2011150061A1 (en) 2011-12-01
EA201291416A1 (ru) 2013-06-28
DK2575846T3 (en) 2015-08-10

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