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MX2010007967A - N-[3-bromo-2-cloro-4-(4,5-dihidro-1h-imidazol-2-ilmetil)-fenil]-m etansulfoamida como agonista parcial alfa-1 a adrenergico para el tratamiento de la incontinencia. - Google Patents

N-[3-bromo-2-cloro-4-(4,5-dihidro-1h-imidazol-2-ilmetil)-fenil]-m etansulfoamida como agonista parcial alfa-1 a adrenergico para el tratamiento de la incontinencia.

Info

Publication number
MX2010007967A
MX2010007967A MX2010007967A MX2010007967A MX2010007967A MX 2010007967 A MX2010007967 A MX 2010007967A MX 2010007967 A MX2010007967 A MX 2010007967A MX 2010007967 A MX2010007967 A MX 2010007967A MX 2010007967 A MX2010007967 A MX 2010007967A
Authority
MX
Mexico
Prior art keywords
alpha
partial agonist
methanesulfoamide
pheny
incontinence
Prior art date
Application number
MX2010007967A
Other languages
English (en)
Inventor
Counde O'yang
Dennis Mitsugu Yasuda
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2010007967A publication Critical patent/MX2010007967A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un agonista parcial del receptor alfa-1A, que es representado por la Fórmula I: y las sales y solvatos farmacéuticamente aceptables del mismo. La invención se refiere además a las composiciones farmacéuticas que contienen la fórmula I, los métodos para su uso como agentes terapéuticos, y los métodos de preparación de los mismos.
MX2010007967A 2008-02-04 2009-01-26 N-[3-bromo-2-cloro-4-(4,5-dihidro-1h-imidazol-2-ilmetil)-fenil]-m etansulfoamida como agonista parcial alfa-1 a adrenergico para el tratamiento de la incontinencia. MX2010007967A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2583908P 2008-02-04 2008-02-04
PCT/EP2009/050838 WO2009098134A1 (en) 2008-02-04 2009-01-26 N-[3-bromo-2-chloro-4-(4, 5-dihydro-1h-imidazol-2-ylmethyl)-phenyl] -methanesulfoamide as alpha-1 a adrenergic partial agonist for the treatment of incontinence

Publications (1)

Publication Number Publication Date
MX2010007967A true MX2010007967A (es) 2010-08-09

Family

ID=40445735

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010007967A MX2010007967A (es) 2008-02-04 2009-01-26 N-[3-bromo-2-cloro-4-(4,5-dihidro-1h-imidazol-2-ilmetil)-fenil]-m etansulfoamida como agonista parcial alfa-1 a adrenergico para el tratamiento de la incontinencia.

Country Status (11)

Country Link
US (2) US20090197932A1 (es)
EP (1) EP2238113A1 (es)
JP (1) JP2011511024A (es)
KR (1) KR20100095649A (es)
CN (1) CN101925582A (es)
AU (1) AU2009211504A1 (es)
BR (1) BRPI0906982A2 (es)
CA (1) CA2711871A1 (es)
IL (1) IL206674A0 (es)
MX (1) MX2010007967A (es)
WO (1) WO2009098134A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2238116B1 (en) * 2008-02-04 2011-09-21 F. Hoffmann-La Roche AG Novel imidazolinylmethyl aryl sulfonamides
WO2022047052A1 (en) * 2020-08-27 2022-03-03 Curasen Therapeutics, Inc. α1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535823A (en) * 2002-04-23 2007-07-27 Hoffmann La Roche Imidazolin-2-ylmethyl substituted aralkylsulfonamides

Also Published As

Publication number Publication date
EP2238113A1 (en) 2010-10-13
IL206674A0 (en) 2010-12-30
JP2011511024A (ja) 2011-04-07
AU2009211504A1 (en) 2009-08-13
KR20100095649A (ko) 2010-08-31
BRPI0906982A2 (pt) 2015-07-21
WO2009098134A1 (en) 2009-08-13
CA2711871A1 (en) 2009-08-13
CN101925582A (zh) 2010-12-22
US20090197932A1 (en) 2009-08-06
US20110237639A1 (en) 2011-09-29

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal