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MX2009009541A - Inhibidores de metaloproteasa que contienen una porcion heterociclica. - Google Patents

Inhibidores de metaloproteasa que contienen una porcion heterociclica.

Info

Publication number
MX2009009541A
MX2009009541A MX2009009541A MX2009009541A MX2009009541A MX 2009009541 A MX2009009541 A MX 2009009541A MX 2009009541 A MX2009009541 A MX 2009009541A MX 2009009541 A MX2009009541 A MX 2009009541A MX 2009009541 A MX2009009541 A MX 2009009541A
Authority
MX
Mexico
Prior art keywords
heterocyclic
heterocyclic moiety
metalloprotease inhibitors
inhibitors containing
moiety
Prior art date
Application number
MX2009009541A
Other languages
English (en)
Inventor
Christian Gege
Arthur Taveras
Original Assignee
Alantos Pharm Holding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alantos Pharm Holding filed Critical Alantos Pharm Holding
Publication of MX2009009541A publication Critical patent/MX2009009541A/es

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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Abstract

La presente invención se refiere generalmente a agentes farmacéuticos que contienen una porción heterocíclica, y en particular, a compuestos que inhiben la metaloproteasa heterocíclicos. Más particularmente, la presente invención proporciona una nueva clase de compuestos que inhiben MMP-13 heterocíclicos con una porción de benzoxazina modificada, que exhibe una potencia y selectividad aumentada en relación con los inhibidores MMP-13 actualmente conocidos.
MX2009009541A 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica. MX2009009541A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90556507P 2007-03-07 2007-03-07
PCT/US2008/003191 WO2008109177A2 (en) 2007-03-07 2008-03-07 Metalloprotease inhibitors containing a heterocyclic moiety

Publications (1)

Publication Number Publication Date
MX2009009541A true MX2009009541A (es) 2009-09-16

Family

ID=39551667

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2009009540A MX2009009540A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.
MX2009009552A MX2009009552A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.
MX2009009541A MX2009009541A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2009009540A MX2009009540A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.
MX2009009552A MX2009009552A (es) 2007-03-07 2008-03-07 Inhibidores de metaloproteasa que contienen una porcion heterociclica.

Country Status (7)

Country Link
US (5) US20080221094A1 (es)
EP (3) EP2125816A2 (es)
JP (3) JP2010520294A (es)
AU (3) AU2008223351A1 (es)
CA (3) CA2680177A1 (es)
MX (3) MX2009009540A (es)
WO (5) WO2008109178A1 (es)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7728031B2 (en) * 2006-02-24 2010-06-01 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole derivatives
CA2670026A1 (en) * 2006-11-20 2008-05-29 Alantos Pharmaceuticals Holding, Inc. Heterotricyclic metalloprotease inhibitors
EP2188288A1 (en) * 2007-09-11 2010-05-26 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole n-oxides
JP5432982B2 (ja) 2008-03-31 2014-03-05 武田薬品工業株式会社 アポトーシスシグナル調節キナーゼ１阻害剤
CA2732437C (en) 2008-08-01 2017-11-21 Ventirx Pharmaceuticals, Inc. Toll-like receptor agonist formulations and their use
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