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AP2007004119A0 - Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same - Google Patents

Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

Info

Publication number
AP2007004119A0
AP2007004119A0 AP2007004119A AP2007004119A AP2007004119A0 AP 2007004119 A0 AP2007004119 A0 AP 2007004119A0 AP 2007004119 A AP2007004119 A AP 2007004119A AP 2007004119 A AP2007004119 A AP 2007004119A AP 2007004119 A0 AP2007004119 A0 AP 2007004119A0
Authority
AP
ARIPO
Prior art keywords
ion
methods
same
pharmaceutical compositions
amide derivatives
Prior art date
Application number
AP2007004119A
Inventor
Mathew Duncton
Zhi-Liang Wei
Kiran Sahasrabudhe
Original Assignee
Renovis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovis Inc filed Critical Renovis Inc
Publication of AP2007004119A0 publication Critical patent/AP2007004119A0/en

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    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
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    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
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    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D491/04—Ortho-condensed systems
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US7576099B2 (en) 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
EP2139887A2 (en) * 2007-03-07 2010-01-06 Alantos Pharmaceuticals Holding, Inc. Metalloprotease inhibitors containing a heterocyclic moiety
US8853392B2 (en) 2007-06-03 2014-10-07 Vanderbilt University Benzamide mGluR5 positive allosteric modulators and methods of making and using same
SG185285A1 (en) * 2007-06-03 2012-11-29 Univ Vanderbilt Benzamide mglur5 positive allosteric modulators and methods of making and using same
CA2703220A1 (en) * 2007-11-13 2009-05-22 Pfizer Global Research And Development Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
CA2705835A1 (en) * 2007-11-16 2009-05-22 Neuraxon, Inc. Indole compounds and methods for treating visceral pain
FR2933977B1 (en) * 2008-07-18 2013-04-26 Centre Nat Rech Scient HETEROCYCLIC DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES
WO2011016234A1 (en) * 2009-08-04 2011-02-10 Raqualia Pharma Inc. Picolinamide derivatives as ttx-s blockers
US20140113824A1 (en) 2011-05-10 2014-04-24 Bayer Intellectual Property Gmbh Bicyclic (thio)carbonylamidines
US9193706B2 (en) * 2011-09-29 2015-11-24 Mitsui Chemicals Agro, Inc. Method for producing 3,4-dihydroisoquinoline derivatives and production intermediates of same
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US9029368B2 (en) 2011-11-30 2015-05-12 Actelion Pharmaceuticals Ltd. 3,7-disubstituted octahydro-2H-pyrido[4,3-E][1,3]oxazin-2-one antibiotics
WO2014113467A1 (en) * 2013-01-15 2014-07-24 Board Of Regents, The University Of Texas System Stat3 inhibitor
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