MX2009008617A - Uso de antagonistas de interleucina-23 para el tratamiento de infeccion. - Google Patents
Uso de antagonistas de interleucina-23 para el tratamiento de infeccion.Info
- Publication number
- MX2009008617A MX2009008617A MX2009008617A MX2009008617A MX2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A MX 2009008617 A MX2009008617 A MX 2009008617A
- Authority
- MX
- Mexico
- Prior art keywords
- antagonists
- treatment
- infection
- infections
- viral
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se proveen métodos y composiciones que comprenden antagonistas de IL-23 para el tratamiento de infecciones, tales como infecciones bacterianas, virales y fúngicas crónicas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88947507P | 2007-02-12 | 2007-02-12 | |
| PCT/US2008/001717 WO2008153610A2 (en) | 2007-02-12 | 2008-02-08 | Use of il-23 antagonists for treatment of infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009008617A true MX2009008617A (es) | 2009-10-14 |
Family
ID=40130357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009008617A MX2009008617A (es) | 2007-02-12 | 2008-02-08 | Uso de antagonistas de interleucina-23 para el tratamiento de infeccion. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8586035B2 (es) |
| EP (1) | EP2064246B1 (es) |
| JP (2) | JP5320301B2 (es) |
| CN (1) | CN101668775B (es) |
| AU (1) | AU2008262544B2 (es) |
| BR (1) | BRPI0807487A8 (es) |
| CA (1) | CA2677835A1 (es) |
| CL (1) | CL2008000418A1 (es) |
| MX (1) | MX2009008617A (es) |
| NZ (2) | NZ578955A (es) |
| TW (1) | TWI426918B (es) |
| WO (1) | WO2008153610A2 (es) |
| ZA (1) | ZA200906126B (es) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
| US8513208B2 (en) * | 2008-02-28 | 2013-08-20 | Argos Therapeutics, Inc. | Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection |
| WO2010027767A1 (en) * | 2008-08-27 | 2010-03-11 | Schering Corporation | Engineered anti-il-23r antibodies |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| PE20141162A1 (es) | 2010-11-04 | 2014-09-18 | Boehringer Ingelheim Int | Anticuerpos anti-il-23 |
| EP2661445A2 (en) * | 2011-01-04 | 2013-11-13 | Universität Zürich | Modulators of il-12 and/or il-23 for the prevention or treatment of alzheimer's disease |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| CH707030B1 (de) | 2011-10-21 | 2015-03-13 | Abbvie Inc | Kombinationsbehandlung von DAAs zur Verwendung in der Behandlung von HCV |
| ES2529143B1 (es) | 2011-10-21 | 2015-10-26 | Abbvie Inc. | Combinación de al menos dos agentes antivirales de acción directa, ribavirina pero no interferón para uso de tratamiento del vhc |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| KR102124758B1 (ko) | 2012-05-03 | 2020-06-19 | 베링거 인겔하임 인터내셔날 게엠베하 | 항-il-23p19 항체 |
| WO2014004436A2 (en) | 2012-06-27 | 2014-01-03 | Merck Sharp & Dohme Corp. | Crystalline anti-human il-23 antibodies |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| US10406218B2 (en) * | 2014-04-09 | 2019-09-10 | La Jolla Institute For Allergy And Immunology | Specific and unique T cell responses and molecular signatures for the treatment and diagnosis of Mycobacterium tuberculosis |
| WO2016014775A1 (en) | 2014-07-24 | 2016-01-28 | Boehringer Ingelheim International Gmbh | Biomarkers useful in the treatment of il-23a related diseases |
| UA123624C2 (uk) | 2014-09-03 | 2021-05-05 | Бьорінґер Інґельхайм Інтернаціональ Ґмбх | Сполука, специфічна до іл-23а та фнп-альфа, та її застосування |
| SG11201705728RA (en) | 2015-02-04 | 2017-08-30 | Boehringer Ingelheim Int | Methods of treating inflammatory diseases |
| CN105420238A (zh) * | 2015-09-08 | 2016-03-23 | 中国农业科学院兰州兽医研究所 | 靶向抑制小鼠白细胞介素17A基因的序列siRNA-136 |
| EP3448392A4 (en) | 2016-04-28 | 2020-01-15 | Emory University | ALKYNOUS THERAPEUTIC NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND RELATED APPLICATIONS |
| EP3534910A4 (en) | 2016-10-04 | 2020-11-25 | Pop Test Oncology LLC | THERAPEUTIC METHODS AND AGENTS |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| US11845798B2 (en) | 2017-05-02 | 2023-12-19 | Merck Sharp & Dohme Llc | Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies |
| US20200197389A1 (en) * | 2017-05-12 | 2020-06-25 | The Regents Of The University Of California | Methods for detecting dysbiosis and treating subjects with dysbiosis |
| CN108743603B (zh) * | 2018-06-22 | 2020-06-30 | 山东省千佛山医院 | 利巴韦林单用或联合氟康唑的抗真菌产品及其应用 |
| KR20210089215A (ko) | 2018-11-07 | 2021-07-15 | 머크 샤프 앤드 돔 코포레이션 | 항-lag3 항체 및 항-pd-1 항체의 공동-제제 |
| US20220000944A1 (en) * | 2018-11-09 | 2022-01-06 | The Ritsumeikan Trust | Agent for controlling sebaceous glands |
| CN115135671A (zh) * | 2019-12-20 | 2022-09-30 | 新石生物制药有限公司 | 抗白介素-23 p19的抗体及其使用方法 |
| CN112500490B (zh) * | 2020-10-14 | 2022-05-03 | 华南农业大学 | 一种抗左旋氧氟沙星抗体的F(ab)2片段及其制备方法和应用 |
| CN118873519A (zh) * | 2024-08-22 | 2024-11-01 | 首都医科大学附属北京胸科医院 | 萘替芬在抗偶发分枝杆菌感染中的应用 |
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| US4144346A (en) * | 1977-01-31 | 1979-03-13 | Janssen Pharmaceutica N.V. | Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles |
| US4267179A (en) * | 1978-06-23 | 1981-05-12 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| DE3262386D1 (en) * | 1981-06-06 | 1985-03-28 | Pfizer Ltd | Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them |
| DK0925070T3 (da) * | 1996-09-12 | 2003-12-01 | Merck & Co Inc | Antifungal kombinationsterapi |
| PE20000183A1 (es) | 1997-07-25 | 2000-03-11 | Schering Corp | Citoquinas de mamiferos y reactivos relacionados |
| US6492497B1 (en) * | 1999-04-30 | 2002-12-10 | Cambridge Antibody Technology Limited | Specific binding members for TGFbeta1 |
| EP2258849A1 (en) | 1999-06-01 | 2010-12-08 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
| ES2300276T5 (es) | 1999-09-09 | 2017-06-02 | Merck Sharp & Dohme Corp. | P40 de interleuquina-12 de mamífero e interleuquina B30. Sus combinaciones. Anticuerpos. Usos en composiciones farmacéuticas |
| CA2408571C (en) | 2000-05-10 | 2014-04-29 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
| AUPR381601A0 (en) * | 2001-03-19 | 2001-04-12 | Monash University | Method of treating respiratory conditions |
| WO2002089832A2 (en) * | 2001-05-09 | 2002-11-14 | Alk-Abelló A/S | Pharmaceutical compositions for preventing or treating th1 and th2 cell related diseases by modulating the th1/th2 ratio. |
| WO2004042009A2 (en) * | 2002-10-30 | 2004-05-21 | Genentech, Inc. | Inhibition of il-17 production |
| TWI439285B (zh) * | 2003-03-10 | 2014-06-01 | Merck Sharp & Dohme | Il-23激動劑及拮抗劑之用途及相關試劑 |
| AU2004229527B2 (en) * | 2003-04-11 | 2009-08-20 | Medimmune, Llc | Methods of preventing or treating respiratory conditions |
| AU2004239288B2 (en) * | 2003-05-09 | 2010-01-28 | Centocor, Inc. | IL-23p40 specific immunoglobulin derived proteins, compositions, methods and uses |
| MX341074B (es) | 2003-07-08 | 2016-08-05 | Genentech Inc | Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos. |
| GB0329146D0 (en) | 2003-12-16 | 2004-01-21 | Glaxosmithkline Biolog Sa | Vaccine |
| JP4903061B2 (ja) * | 2004-02-17 | 2012-03-21 | シェーリング コーポレイション | Il−23活性を調節する方法;関連する試薬 |
| US20060193821A1 (en) * | 2004-03-05 | 2006-08-31 | Diener John L | Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics |
| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
| AR051444A1 (es) * | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
| GB0425569D0 (en) * | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Biological products |
| GB0507561D0 (en) | 2005-04-14 | 2005-05-18 | Trinity College Dublin | Modulation of an immune response by filamentous haemagglutinin |
| PT1896073E (pt) * | 2005-06-30 | 2013-05-28 | Janssen Biotech Inc | Composições, métodos e aplicações de anticorpos anti-il-23 |
| ES2347690T3 (es) * | 2005-08-25 | 2010-11-03 | Eli Lilly And Company | Anticuerpos anti-il-23. |
| ME02705B (me) | 2005-08-31 | 2017-10-20 | Merck Sharp & Dohme | Inženjerisana anti-il-23 antitela |
| PT2548577T (pt) | 2005-12-29 | 2017-05-29 | Janssen Biotech Inc | Anticorpos humanos anti-il-23, composições, métodos e usos |
| JP2009540018A (ja) | 2006-06-13 | 2009-11-19 | ザイモジェネティクス, インコーポレイテッド | Il−17およびil−23アンタゴニストならびにその使用方法 |
| AU2007284782B2 (en) * | 2006-08-11 | 2012-11-15 | Merck Sharp & Dohme Corp. | Antibodies to IL-17A |
| TWI426918B (zh) * | 2007-02-12 | 2014-02-21 | Merck Sharp & Dohme | Il-23拮抗劑於治療感染之用途 |
| SI2426144T1 (sl) | 2007-02-23 | 2019-02-28 | Merck Sharp & Dohme Corp. | Umetno proizvedena anti-IL23P19 antitelesa |
| CN101663320A (zh) | 2007-02-23 | 2010-03-03 | 先灵公司 | 工程改造的抗IL-23p19抗体 |
| US8119133B2 (en) | 2007-02-28 | 2012-02-21 | Schering Corporation | Engineered anti-IL-23R antibodies |
| WO2010027767A1 (en) | 2008-08-27 | 2010-03-11 | Schering Corporation | Engineered anti-il-23r antibodies |
-
2008
- 2008-02-05 TW TW097104700A patent/TWI426918B/zh not_active IP Right Cessation
- 2008-02-08 NZ NZ578955A patent/NZ578955A/en not_active IP Right Cessation
- 2008-02-08 EP EP08714214.7A patent/EP2064246B1/en active Active
- 2008-02-08 AU AU2008262544A patent/AU2008262544B2/en not_active Ceased
- 2008-02-08 MX MX2009008617A patent/MX2009008617A/es active IP Right Grant
- 2008-02-08 CL CL2008000418A patent/CL2008000418A1/es unknown
- 2008-02-08 CN CN200880010208.4A patent/CN101668775B/zh not_active Expired - Fee Related
- 2008-02-08 CA CA002677835A patent/CA2677835A1/en not_active Abandoned
- 2008-02-08 BR BRPI0807487A patent/BRPI0807487A8/pt not_active IP Right Cessation
- 2008-02-08 JP JP2009549119A patent/JP5320301B2/ja not_active Expired - Fee Related
- 2008-02-08 US US12/525,003 patent/US8586035B2/en not_active Expired - Fee Related
- 2008-02-08 NZ NZ599827A patent/NZ599827A/xx not_active IP Right Cessation
- 2008-02-08 WO PCT/US2008/001717 patent/WO2008153610A2/en not_active Ceased
-
2009
- 2009-09-03 ZA ZA200906126A patent/ZA200906126B/xx unknown
-
2012
- 2012-10-18 JP JP2012230578A patent/JP2013014624A/ja active Pending
-
2013
- 2013-10-28 US US14/065,171 patent/US20140147442A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008262544B2 (en) | 2014-01-16 |
| TWI426918B (zh) | 2014-02-21 |
| NZ599827A (en) | 2013-11-29 |
| JP5320301B2 (ja) | 2013-10-23 |
| US8586035B2 (en) | 2013-11-19 |
| AU2008262544A1 (en) | 2008-12-18 |
| US20140147442A1 (en) | 2014-05-29 |
| CN101668775A (zh) | 2010-03-10 |
| ZA200906126B (en) | 2010-06-30 |
| JP2010518087A (ja) | 2010-05-27 |
| NZ578955A (en) | 2012-06-29 |
| CN101668775B (zh) | 2014-05-07 |
| WO2008153610A2 (en) | 2008-12-18 |
| BRPI0807487A2 (pt) | 2015-09-01 |
| TW200902062A (en) | 2009-01-16 |
| CL2008000418A1 (es) | 2008-11-14 |
| WO2008153610A3 (en) | 2009-03-19 |
| US20100291084A1 (en) | 2010-11-18 |
| EP2064246B1 (en) | 2013-05-22 |
| BRPI0807487A8 (pt) | 2016-02-10 |
| JP2013014624A (ja) | 2013-01-24 |
| CA2677835A1 (en) | 2008-12-18 |
| EP2064246A2 (en) | 2009-06-03 |
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