MX2009006475A - Composiciones de diclorhidrato de azimilida. - Google Patents
Composiciones de diclorhidrato de azimilida.Info
- Publication number
- MX2009006475A MX2009006475A MX2009006475A MX2009006475A MX2009006475A MX 2009006475 A MX2009006475 A MX 2009006475A MX 2009006475 A MX2009006475 A MX 2009006475A MX 2009006475 A MX2009006475 A MX 2009006475A MX 2009006475 A MX2009006475 A MX 2009006475A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- azimilide dihydrochloride
- dihydrochloride
- azimilide
- furanyl
- Prior art date
Links
- MREBEPTUUMTTIA-PCLIKHOPSA-N Azimilide Chemical group C1CN(C)CCN1CCCCN1C(=O)N(\N=C\C=2OC(=CC=2)C=2C=CC(Cl)=CC=2)CC1=O MREBEPTUUMTTIA-PCLIKHOPSA-N 0.000 title 1
- 229950001786 azimilide Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- HHPSICLSNHCSNZ-BYEGLACWSA-N 1-[(e)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione;dihydrochloride Chemical compound Cl.Cl.C1CN(C)CCN1CCCCN1C(=O)N(\N=C\C=2OC(=CC=2)C=2C=CC(Cl)=CC=2)CC1=O HHPSICLSNHCSNZ-BYEGLACWSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente invención está dirigida a solvatos y diversas formas polimórficas de d ¡clorhidrato de (E)-1 -[[[5-(4-clorofenil)-2- furanhl]metilen]amino]-3-[4-(4-metil-1 -piperazinil)butil]-2,4-imi dazoUdinadiona y composiciones farmacéuticas de éstas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87505106P | 2006-12-15 | 2006-12-15 | |
| PCT/IB2007/055037 WO2008072190A2 (en) | 2006-12-15 | 2007-12-11 | Compositions of azimilide dihydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009006475A true MX2009006475A (es) | 2009-06-26 |
Family
ID=39401118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009006475A MX2009006475A (es) | 2006-12-15 | 2007-12-11 | Composiciones de diclorhidrato de azimilida. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20080182858A1 (es) |
| EP (1) | EP2125791A2 (es) |
| JP (1) | JP2010513264A (es) |
| KR (1) | KR20090089416A (es) |
| CN (1) | CN101558063A (es) |
| AR (1) | AR064367A1 (es) |
| AU (1) | AU2007331033A1 (es) |
| BR (1) | BRPI0720265A2 (es) |
| CA (1) | CA2672132A1 (es) |
| CL (1) | CL2007003643A1 (es) |
| IL (1) | IL198807A0 (es) |
| MA (1) | MA30992B1 (es) |
| MX (1) | MX2009006475A (es) |
| PE (1) | PE20081481A1 (es) |
| RU (1) | RU2009117558A (es) |
| SM (1) | SMAP200900061A (es) |
| TW (1) | TW200840578A (es) |
| WO (1) | WO2008072190A2 (es) |
| ZA (1) | ZA200903390B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016256776B2 (en) * | 2009-03-18 | 2018-04-12 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| AU2013248242B2 (en) * | 2009-03-18 | 2016-08-18 | Incarda Therapeutics, Inc | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| CA2835771C (en) | 2009-03-18 | 2017-01-24 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| CN101735203B (zh) * | 2009-12-17 | 2012-05-23 | 天津药物研究院 | 盐酸阿齐利特的晶型ⅱ及其制备方法和用途 |
| DK3380152T3 (da) * | 2015-11-27 | 2021-02-01 | Sanofi Aventis Deutschland | Medikamentinjektionsanordning |
| SG11201805788WA (en) | 2016-02-01 | 2018-08-30 | Incarda Therapeutics Inc | Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation |
| CA3060702A1 (en) | 2017-05-10 | 2018-11-15 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| WO2019183470A2 (en) | 2018-03-22 | 2019-09-26 | Incarda Therapeutics, Inc. | A novel method to slow ventricular rate |
| US11020384B2 (en) | 2019-08-01 | 2021-06-01 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
| CN113861164B (zh) * | 2021-10-29 | 2022-09-20 | 迪嘉药业集团有限公司 | 一种烟碱的结晶制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4032645A (en) * | 1975-06-19 | 1977-06-28 | G. D. Searle & Co. | Injectable metronidazole composition |
| EP1231208A3 (en) * | 1991-08-14 | 2003-12-10 | Procter & Gamble Pharmaceuticals | 4-oxocyclic ureas useful as antiarrhythmic and antifibrillatory agents |
| NZ506773A (en) * | 1998-04-29 | 2004-03-26 | Procter & Gamble | Process for making 1, 3-disubstituted-4-oxocyclic ureas |
| EP1075473B1 (en) * | 1998-04-29 | 2007-07-04 | The Procter & Gamble Company | Process for making 1,3-disubstituted-4-oxocyclic ureas |
| DE602004024383D1 (de) * | 2003-05-08 | 2010-01-14 | Theravance Inc | Kristalline formen eines arylanilin-beta-2-adrenergenrezeptor-agonists |
-
2007
- 2007-12-07 TW TW096146861A patent/TW200840578A/zh unknown
- 2007-12-11 CA CA002672132A patent/CA2672132A1/en not_active Abandoned
- 2007-12-11 MX MX2009006475A patent/MX2009006475A/es not_active Application Discontinuation
- 2007-12-11 JP JP2009540950A patent/JP2010513264A/ja active Pending
- 2007-12-11 KR KR1020097012327A patent/KR20090089416A/ko not_active Ceased
- 2007-12-11 CN CNA2007800464235A patent/CN101558063A/zh active Pending
- 2007-12-11 US US12/001,321 patent/US20080182858A1/en not_active Abandoned
- 2007-12-11 AU AU2007331033A patent/AU2007331033A1/en not_active Abandoned
- 2007-12-11 RU RU2009117558/04A patent/RU2009117558A/ru not_active Application Discontinuation
- 2007-12-11 EP EP07849435A patent/EP2125791A2/en not_active Withdrawn
- 2007-12-11 BR BRPI0720265-2A patent/BRPI0720265A2/pt not_active Application Discontinuation
- 2007-12-11 WO PCT/IB2007/055037 patent/WO2008072190A2/en not_active Ceased
- 2007-12-13 PE PE2007001784A patent/PE20081481A1/es not_active Application Discontinuation
- 2007-12-14 AR ARP070105639A patent/AR064367A1/es not_active Application Discontinuation
- 2007-12-14 CL CL200703643A patent/CL2007003643A1/es unknown
-
2009
- 2009-05-18 ZA ZA200903390A patent/ZA200903390B/xx unknown
- 2009-05-19 IL IL198807A patent/IL198807A0/en unknown
- 2009-06-15 MA MA31991A patent/MA30992B1/fr unknown
- 2009-07-15 SM SM200900061T patent/SMAP200900061A/it unknown
-
2011
- 2011-06-09 US US13/156,810 patent/US20110237603A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2672132A1 (en) | 2008-06-19 |
| WO2008072190A2 (en) | 2008-06-19 |
| BRPI0720265A2 (pt) | 2014-01-28 |
| US20110237603A1 (en) | 2011-09-29 |
| US20080182858A1 (en) | 2008-07-31 |
| AR064367A1 (es) | 2009-04-01 |
| WO2008072190A3 (en) | 2008-11-06 |
| TW200840578A (en) | 2008-10-16 |
| CN101558063A (zh) | 2009-10-14 |
| PE20081481A1 (es) | 2008-11-07 |
| EP2125791A2 (en) | 2009-12-02 |
| RU2009117558A (ru) | 2011-01-20 |
| KR20090089416A (ko) | 2009-08-21 |
| AU2007331033A1 (en) | 2008-06-19 |
| CL2007003643A1 (es) | 2008-03-24 |
| ZA200903390B (en) | 2010-04-28 |
| MA30992B1 (fr) | 2009-12-01 |
| IL198807A0 (en) | 2010-02-17 |
| SMAP200900061A (it) | 2009-09-07 |
| JP2010513264A (ja) | 2010-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or rights |
Owner name: WARNER CHILCOTT COMPANY, LLC |
|
| FA | Abandonment or withdrawal |