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MX2009004048A - Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-pi perazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona. - Google Patents

Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-pi perazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona.

Info

Publication number
MX2009004048A
MX2009004048A MX2009004048A MX2009004048A MX2009004048A MX 2009004048 A MX2009004048 A MX 2009004048A MX 2009004048 A MX2009004048 A MX 2009004048A MX 2009004048 A MX2009004048 A MX 2009004048A MX 2009004048 A MX2009004048 A MX 2009004048A
Authority
MX
Mexico
Prior art keywords
quinazolin
piperazin
pyrrole
methyl
ind0l
Prior art date
Application number
MX2009004048A
Other languages
English (en)
Inventor
Dimitris Papoutsakis
Piotr Karpinski
Paul Allen Sutton
Stephanie Monnier
Elias Ndzie
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38921707&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009004048(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009004048A publication Critical patent/MX2009004048A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La invención se refiere a una nueva forma cristalina de la sal de acetato de 3-(1.H.-indol-3-il)-4-[2-(4-metil-piperazin-1-il)-quina zolin-4-il]-pirrol-2,5-diona, la cual se puede utilizar, por ejemplo, para trasplante.
MX2009004048A 2006-10-20 2007-10-18 Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-pi perazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona. MX2009004048A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85338406P 2006-10-20 2006-10-20
PCT/US2007/022241 WO2008051440A1 (en) 2006-10-20 2007-10-18 Crystal modifications -3- (1h-ind0l-3-yl) -4- [2- (4-methyl-piperazin-1-yl) -quinazolin-4-yl] -pyrrole-2, 5-d ione

Publications (1)

Publication Number Publication Date
MX2009004048A true MX2009004048A (es) 2009-04-27

Family

ID=38921707

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009004048A MX2009004048A (es) 2006-10-20 2007-10-18 Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-pi perazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona.

Country Status (23)

Country Link
US (1) US8865897B2 (es)
EP (1) EP2102195A1 (es)
JP (1) JP5302199B2 (es)
KR (1) KR20090073231A (es)
CN (2) CN103265533A (es)
AR (1) AR063491A1 (es)
AU (1) AU2007309558B2 (es)
BR (1) BRPI0717461A2 (es)
CA (1) CA2666965A1 (es)
CL (1) CL2007003006A1 (es)
EC (1) ECSP099344A (es)
IL (1) IL197962A (es)
MA (1) MA30886B1 (es)
MX (1) MX2009004048A (es)
MY (1) MY158026A (es)
NO (1) NO20091970L (es)
NZ (1) NZ576241A (es)
PE (1) PE20081133A1 (es)
RU (1) RU2481341C2 (es)
TN (1) TN2009000147A1 (es)
TW (1) TWI399374B (es)
WO (1) WO2008051440A1 (es)
ZA (1) ZA200902048B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010520879A (ja) * 2007-03-09 2010-06-17 ノバルティス アーゲー ３−（１ｈ−インドール−３−イル）−４−［２−（４−メチル−ピペラジン−１−イル）−キナゾリン−４−イル］−ピロール−２，５−ジオンの塩
US9017528B2 (en) 2011-04-14 2015-04-28 Tel Nexx, Inc. Electro chemical deposition and replenishment apparatus
US9005409B2 (en) 2011-04-14 2015-04-14 Tel Nexx, Inc. Electro chemical deposition and replenishment apparatus
US9303329B2 (en) 2013-11-11 2016-04-05 Tel Nexx, Inc. Electrochemical deposition apparatus with remote catholyte fluid management

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020544A1 (es) * 2000-11-07 2002-07-30 Novartis Ag Derivados de indolilmaleimida
GB0504203D0 (en) * 2005-03-01 2005-04-06 Novartis Ag Organic compounds
MX2009013431A (es) 2007-06-18 2010-01-15 Sanofi Aventis Derivados de pirrol como antagonistas de p2y12.

Also Published As

Publication number Publication date
CN101522664B (zh) 2013-06-12
CN101522664A (zh) 2009-09-02
CL2007003006A1 (es) 2008-05-23
US8865897B2 (en) 2014-10-21
AU2007309558B2 (en) 2012-05-24
JP2010506927A (ja) 2010-03-04
RU2009118816A (ru) 2010-11-27
BRPI0717461A2 (pt) 2013-10-08
CA2666965A1 (en) 2008-05-02
TW200829572A (en) 2008-07-16
CN103265533A (zh) 2013-08-28
WO2008051440A1 (en) 2008-05-02
NO20091970L (no) 2009-05-20
AU2007309558A1 (en) 2008-05-02
KR20090073231A (ko) 2009-07-02
TN2009000147A1 (en) 2010-10-18
AR063491A1 (es) 2009-01-28
MY158026A (en) 2016-08-30
RU2481341C2 (ru) 2013-05-10
ECSP099344A (es) 2009-06-30
EP2102195A1 (en) 2009-09-23
TWI399374B (zh) 2013-06-21
NZ576241A (en) 2012-05-25
PE20081133A1 (es) 2008-09-16
IL197962A (en) 2013-08-29
US20100041884A1 (en) 2010-02-18
IL197962A0 (en) 2009-12-24
ZA200902048B (en) 2010-01-27
MA30886B1 (fr) 2009-11-02
JP5302199B2 (ja) 2013-10-02

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MX2009004048A (es) Modificaciones de cristal de la 3-(1h-indol-3-il)-4-[2-(4-metil-pi perazin-1-il)-quinazolin-4-il]-pirrol-2,5-diona.

Legal Events

Date Code Title Description
HH Correction or change in general
FG Grant or registration