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MX2009001188A - Compuestos quimicos. - Google Patents

Compuestos quimicos.

Info

Publication number
MX2009001188A
MX2009001188A MX2009001188A MX2009001188A MX2009001188A MX 2009001188 A MX2009001188 A MX 2009001188A MX 2009001188 A MX2009001188 A MX 2009001188A MX 2009001188 A MX2009001188 A MX 2009001188A MX 2009001188 A MX2009001188 A MX 2009001188A
Authority
MX
Mexico
Prior art keywords
disorders
chemical compounds
lymphopenia
preparation
treatment
Prior art date
Application number
MX2009001188A
Other languages
English (en)
Inventor
Ghotas Evindar
Sylvie Bernier
Gang Yao
Aaron Coffin
Hongfang Yang
Hongfeng Deng
Original Assignee
Praecis Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praecis Pharm Inc filed Critical Praecis Pharm Inc
Publication of MX2009001188A publication Critical patent/MX2009001188A/es

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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Pain & Pain Management (AREA)

Abstract

La invención provee compuestos de la fórmula I, su preparación, y su uso como agente inmunosupresores farmacéuticamente activos para el tratamiento de trastornos autoinmunes, rechazo de trasplante de órganos, trastornos asociados con un sistema inmunológico activado, así como otros trastornos modulados por linfopenia o receptores de S1P.
MX2009001188A 2006-08-01 2007-08-01 Compuestos quimicos. MX2009001188A (es)

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US82110106P 2006-08-01 2006-08-01
US82791906P 2006-10-03 2006-10-03
US89643107P 2007-03-22 2007-03-22
US95929107P 2007-07-12 2007-07-12
PCT/US2007/017282 WO2008016692A2 (en) 2006-08-01 2007-08-01 Chemical compounds

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JP (1) JP2009545599A (es)
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AR (1) AR062156A1 (es)
AU (1) AU2007281491A1 (es)
BR (1) BRPI0714512A2 (es)
CA (1) CA2659473A1 (es)
CO (1) CO6150145A2 (es)
CR (1) CR10628A (es)
EA (1) EA200970173A1 (es)
IL (1) IL196595A0 (es)
MA (1) MA30639B1 (es)
MX (1) MX2009001188A (es)
NO (1) NO20090739L (es)
PE (1) PE20080730A1 (es)
TW (1) TW200823182A (es)
WO (1) WO2008016692A2 (es)

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EP2046746A2 (en) 2009-04-15
AU2007281491A1 (en) 2008-02-07
EA200970173A1 (ru) 2009-10-30
KR20090033912A (ko) 2009-04-06
AR062156A1 (es) 2008-10-22
WO2008016692A3 (en) 2008-03-20
US20080096938A1 (en) 2008-04-24
NO20090739L (no) 2009-04-24
TW200823182A (en) 2008-06-01
US20100009936A1 (en) 2010-01-14
IL196595A0 (en) 2009-11-18
US7759370B2 (en) 2010-07-20
PE20080730A1 (es) 2008-06-12
JP2009545599A (ja) 2009-12-24
WO2008016692A2 (en) 2008-02-07
MA30639B1 (fr) 2009-08-03
BRPI0714512A2 (pt) 2015-06-16
CA2659473A1 (en) 2008-02-07
CR10628A (es) 2009-04-28
CO6150145A2 (es) 2010-04-20

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