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MX2007006374A - Derivados del 5-hidroxi-benzotiazol que tienen actividad agonista del adrenoreceptor-beta-2. - Google Patents

Derivados del 5-hidroxi-benzotiazol que tienen actividad agonista del adrenoreceptor-beta-2.

Info

Publication number
MX2007006374A
MX2007006374A MX2007006374A MX2007006374A MX2007006374A MX 2007006374 A MX2007006374 A MX 2007006374A MX 2007006374 A MX2007006374 A MX 2007006374A MX 2007006374 A MX2007006374 A MX 2007006374A MX 2007006374 A MX2007006374 A MX 2007006374A
Authority
MX
Mexico
Prior art keywords
beta
hydroxy
agonist activity
benzothiazole derivatives
adrenorecptor
Prior art date
Application number
MX2007006374A
Other languages
English (en)
Inventor
Robin Alec Fairhurst
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2007006374A publication Critical patent/MX2007006374A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Los compuestos de la formula (I) en forma libre o de sal o de solvato en donde T tiene el significado como se marca en la especificacion, son utiles para el tratamiento de condiciones que son prevenidas o aliviadas por la activacion del adrenoreceptor-(2. Las composiciones farmaceuticas que contienen los compuestos y un proceso para la preparacion de los compuestos tambien son descritas. (ver formula (I)).
MX2007006374A 2004-11-29 2005-11-28 Derivados del 5-hidroxi-benzotiazol que tienen actividad agonista del adrenoreceptor-beta-2. MX2007006374A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0426164.0A GB0426164D0 (en) 2004-11-29 2004-11-29 Organic compounds
PCT/EP2005/012686 WO2006056471A1 (en) 2004-11-29 2005-11-28 5-hydroxy-benzothiazole derivatives having beta-2-adrenorecptor agonist activity

Publications (1)

Publication Number Publication Date
MX2007006374A true MX2007006374A (es) 2007-06-20

Family

ID=33561510

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006374A MX2007006374A (es) 2004-11-29 2005-11-28 Derivados del 5-hidroxi-benzotiazol que tienen actividad agonista del adrenoreceptor-beta-2.

Country Status (19)

Country Link
US (2) US8076489B2 (es)
EP (2) EP2305659A1 (es)
JP (1) JP4648950B2 (es)
KR (1) KR100891415B1 (es)
CN (1) CN101065370B (es)
AT (1) ATE520676T1 (es)
AU (1) AU2005308909C1 (es)
BR (1) BRPI0517894A (es)
CA (1) CA2586443C (es)
CY (1) CY1112237T1 (es)
DK (1) DK1819686T3 (es)
ES (1) ES2370833T3 (es)
GB (1) GB0426164D0 (es)
MX (1) MX2007006374A (es)
PL (1) PL1819686T3 (es)
PT (1) PT1819686E (es)
RU (1) RU2402540C2 (es)
SI (1) SI1819686T1 (es)
WO (1) WO2006056471A1 (es)

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JO3192B1 (ar) 2011-09-06 2018-03-08 Novartis Ag مركب بنزوثيازولون
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CY1112237T1 (el) 2015-12-09
US20120041041A1 (en) 2012-02-16
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RU2402540C2 (ru) 2010-10-27
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AU2005308909B2 (en) 2009-08-27
CA2586443A1 (en) 2006-06-01
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AU2005308909A1 (en) 2006-06-01
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ATE520676T1 (de) 2011-09-15
US8076489B2 (en) 2011-12-13
CN101065370A (zh) 2007-10-31
BRPI0517894A (pt) 2008-10-21
ES2370833T3 (es) 2011-12-23
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