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ME03540B - Transdermalne kompozicije ibuprofena i postupci za njihovu upotrebu - Google Patents

Transdermalne kompozicije ibuprofena i postupci za njihovu upotrebu

Info

Publication number
ME03540B
ME03540B MEP-2019-275A MEP2019275A ME03540B ME 03540 B ME03540 B ME 03540B ME P2019275 A MEP2019275 A ME P2019275A ME 03540 B ME03540 B ME 03540B
Authority
ME
Montenegro
Prior art keywords
ibuprofen
transdermal compositions
transdermal
compositions
Prior art date
Application number
MEP-2019-275A
Other languages
German (de)
English (en)
French (fr)
Inventor
Haigang Chen
Gareth Winckle
Christopher Riley
Original Assignee
Aponia Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47108054&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME03540(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aponia Laboratories Inc filed Critical Aponia Laboratories Inc
Publication of ME03540B publication Critical patent/ME03540B/me

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
MEP-2019-275A 2011-05-03 2012-05-03 Transdermalne kompozicije ibuprofena i postupci za njihovu upotrebu ME03540B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161482058P 2011-05-03 2011-05-03
EP12779275.2A EP2704703B1 (en) 2011-05-03 2012-05-03 Transdermal compositions of ibuprofen and methods of use thereof
PCT/US2012/036366 WO2012151427A1 (en) 2011-05-03 2012-05-03 Transdermal compositions of ibuprofen and methods of use thereof

Publications (1)

Publication Number Publication Date
ME03540B true ME03540B (me) 2020-07-20

Family

ID=47108054

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2019-275A ME03540B (me) 2011-05-03 2012-05-03 Transdermalne kompozicije ibuprofena i postupci za njihovu upotrebu

Country Status (26)

Country Link
US (7) US9205041B2 (me)
EP (2) EP2704703B1 (me)
JP (1) JP5989095B2 (me)
KR (1) KR101926211B1 (me)
CN (1) CN103717213B (me)
AU (3) AU2012250664B2 (me)
BR (1) BR112013028435A2 (me)
CA (1) CA2835062C (me)
CL (1) CL2013003163A1 (me)
CO (1) CO6862148A2 (me)
CY (1) CY1122273T1 (me)
DK (1) DK2704703T3 (me)
EA (1) EA026697B1 (me)
ES (1) ES2749323T3 (me)
HR (1) HRP20191806T1 (me)
HU (1) HUE046750T2 (me)
LT (1) LT2704703T (me)
ME (1) ME03540B (me)
MX (1) MX365427B (me)
PE (2) PE20140936A1 (me)
PL (1) PL2704703T3 (me)
PT (1) PT2704703T (me)
RS (1) RS59484B1 (me)
SI (1) SI2704703T1 (me)
SM (1) SMT201900595T1 (me)
WO (1) WO2012151427A1 (me)

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JP6632810B2 (ja) * 2015-03-31 2020-01-22 小林製薬株式会社 外用医薬組成物
US10383825B2 (en) 2015-08-13 2019-08-20 Temple University—Of the Commonwealth System of Higher Education Calcium alginate dosage formulations, and methods of making and using thereof
BR112018070140A2 (pt) 2016-03-31 2019-02-05 Smartech Topical, Inc. sistema de distribuição
GB201609968D0 (en) 2016-06-07 2016-07-20 Futura Medical Dev Ltd Topical pharmaceutical formulation
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US20190298688A1 (en) * 2016-11-21 2019-10-03 Vivier Canada Inc. Putrescine slow-release topical formulations
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US12042487B2 (en) 2018-11-16 2024-07-23 Arcutis Biotherapeutics, Inc. Method for reducing side effects from administration of phosphodiesterase-4 inhibitors
US9895359B1 (en) 2017-06-07 2018-02-20 Arcutis, Inc. Inhibition of crystal growth of roflumilast
US12011437B1 (en) 2017-06-07 2024-06-18 Arcutis Biotherapeutics, Inc. Roflumilast formulations with an improved pharmacokinetic profile
US20210161870A1 (en) 2017-06-07 2021-06-03 Arcutis Biotherapeutics, Inc. Roflumilast formulations with an improved pharmacokinetic profile
US11129818B2 (en) 2017-06-07 2021-09-28 Arcutis Biotherapeutics, Inc. Topical roflumilast formulation having improved delivery and plasma half life
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US11534493B2 (en) * 2017-09-22 2022-12-27 Arcutis Biotherapeutics, Inc. Pharmaceutical compositions of roflumilast in aqueous blends of water-miscible, pharmaceutically acceptable solvents
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WO2019236374A2 (en) 2018-06-04 2019-12-12 Arcutis, Inc. Method and formulation for improving roflumilast skin penetration lag time
CN109432061B (zh) * 2018-11-09 2020-10-30 北京德默高科医药技术有限公司 含有布洛芬或其结构类似物的多层经皮给药系统
MX2022005168A (es) 2019-11-06 2022-06-08 Smartech Topical Inc Formulaciones topicas de inhibidores de la ciclooxigenasa y su uso.
CA3162675C (en) 2020-12-04 2023-09-26 Saori Kato Topical roflumilast formulation having antifungal properties
US11844753B2 (en) 2021-11-08 2023-12-19 Weiyong Li Transdermal drug delivery system for delivering a drug to a patient
AU2022429340A1 (en) 2021-12-28 2024-08-01 Arcutis Biotherapeutics, Inc. Topical roflumilast aerosol foams
KR20250057103A (ko) 2022-09-15 2025-04-28 아큐티스 바이오테라퓨틱스, 인크. 로플루밀라스트 및 많은 양의 약물을 용해시킬 수 있는 용매의 약학 조성물

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Also Published As

Publication number Publication date
EA201391623A1 (ru) 2014-06-30
ES2749323T3 (es) 2020-03-19
RS59484B1 (sr) 2019-12-31
AU2019203188A1 (en) 2019-05-30
US20220387301A1 (en) 2022-12-08
CA2835062A1 (en) 2012-11-08
US20130005816A1 (en) 2013-01-03
US20180125779A1 (en) 2018-05-10
HRP20191806T1 (hr) 2020-01-10
US20160331678A1 (en) 2016-11-17
US9205041B2 (en) 2015-12-08
US10821071B2 (en) 2020-11-03
AU2012250664A1 (en) 2013-12-19
KR101926211B1 (ko) 2019-02-26
CY1122273T1 (el) 2020-11-25
SMT201900595T1 (it) 2019-11-13
US20240108569A1 (en) 2024-04-04
AU2012250664B2 (en) 2017-04-20
EP3560485A1 (en) 2019-10-30
CL2013003163A1 (es) 2014-07-04
EP2704703A1 (en) 2014-03-12
CN103717213B (zh) 2016-11-09
CO6862148A2 (es) 2014-02-10
US11419814B2 (en) 2022-08-23
WO2012151427A1 (en) 2012-11-08
BR112013028435A2 (pt) 2017-01-24
EP2704703A4 (en) 2014-12-03
PE20140936A1 (es) 2014-08-06
DK2704703T3 (da) 2019-10-14
KR20140041504A (ko) 2014-04-04
US20230248640A1 (en) 2023-08-10
PT2704703T (pt) 2019-10-25
SI2704703T1 (sl) 2019-12-31
US9849080B2 (en) 2017-12-26
JP2014513132A (ja) 2014-05-29
CA2835062C (en) 2019-08-13
NZ618259A (en) 2016-02-26
EA026697B1 (ru) 2017-05-31
AU2017204878A1 (en) 2017-08-03
CN103717213A (zh) 2014-04-09
US20210045999A1 (en) 2021-02-18
NZ703779A (en) 2016-10-28
PE20180399A1 (es) 2018-02-28
MX365427B (es) 2019-06-03
LT2704703T (lt) 2019-12-10
MX2013012832A (es) 2015-01-22
HUE046750T2 (hu) 2020-03-30
PL2704703T3 (pl) 2020-03-31
JP5989095B2 (ja) 2016-09-07
EP2704703B1 (en) 2019-07-24

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