MD107C2 - Transdermal therapeutical system - Google Patents
Transdermal therapeutical systemInfo
- Publication number
- MD107C2 MD107C2 MD94-0095A MD940095A MD107C2 MD 107 C2 MD107 C2 MD 107C2 MD 940095 A MD940095 A MD 940095A MD 107 C2 MD107 C2 MD 107C2
- Authority
- MD
- Moldova
- Prior art keywords
- physostigmine
- weight
- layer
- base
- reservoir layer
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- PIJVFDBKTWXHHD-UHFFFAOYSA-N Physostigmine Natural products C12=CC(OC(=O)NC)=CC=C2N(C)C2C1(C)CCN2C PIJVFDBKTWXHHD-UHFFFAOYSA-N 0.000 abstract 3
- PIJVFDBKTWXHHD-HIFRSBDPSA-N physostigmine Chemical compound C12=CC(OC(=O)NC)=CC=C2N(C)[C@@H]2[C@@]1(C)CCN2C PIJVFDBKTWXHHD-HIFRSBDPSA-N 0.000 abstract 3
- 229960001697 physostigmine Drugs 0.000 abstract 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 abstract 2
- 150000002170 ethers Chemical class 0.000 abstract 2
- LLVWLCAZSOLOTF-UHFFFAOYSA-N 1-methyl-4-[1,4,4-tris(4-methylphenyl)buta-1,3-dienyl]benzene Chemical compound C1=CC(C)=CC=C1C(C=1C=CC(C)=CC=1)=CC=C(C=1C=CC(C)=CC=1)C1=CC=C(C)C=C1 LLVWLCAZSOLOTF-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 229920002367 Polyisobutene Polymers 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229920001400 block copolymer Polymers 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000002861 polymer material Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention relates to the medicine especially to the transdermal therapeutical system, which contains physostigmine as an active component part. The purpose of the invention consists in the increasing of time of cheeking casualness of physostigmine and of its stability at the system keeping.The system is constituted from unpenetrable tegumental layer for active substance, stocky reservoir layer, in case of necessity from protecting layer of detachment. Reservoir layer contains 67-90% weight of polymer material from block copolymer group on styrene base and 1,3 diene, polyisobutylene, polymer on acrylate base and/or mateckylate and complex ethers of hydrogenated calophonium, as well as 10-25% weight of softener on hydrocarbon base and/or complex ethers and 6,3-11,7% weight of physostigmine.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3843239A DE3843239C1 (en) | 1988-12-22 | 1988-12-22 | |
| SU894742793A RU2011384C1 (en) | 1988-12-22 | 1989-12-21 | Transdermal therapeutic system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD107B1 MD107B1 (en) | 1994-12-31 |
| MD107C2 true MD107C2 (en) | 1995-07-31 |
Family
ID=25875486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0095A MD107C2 (en) | 1988-12-22 | 1994-04-28 | Transdermal therapeutical system |
Country Status (2)
| Country | Link |
|---|---|
| LV (1) | LV5578A3 (en) |
| MD (1) | MD107C2 (en) |
-
1993
- 1993-06-30 LV LV930925A patent/LV5578A3/en unknown
-
1994
- 1994-04-28 MD MD94-0095A patent/MD107C2/en active IP Right Grant
Non-Patent Citations (1)
| Title |
|---|
| Cererea nr. 3606892, DE, A 61 K 31/465, A 61 K 31/44, 1988. * |
Also Published As
| Publication number | Publication date |
|---|---|
| LV5578A3 (en) | 1994-05-10 |
| MD107B1 (en) | 1994-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20090427 |