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MC1639A1 - Derives de la glycerine - Google Patents

Derives de la glycerine

Info

Publication number
MC1639A1
MC1639A1 MC841745A MC1745A MC1639A1 MC 1639 A1 MC1639 A1 MC 1639A1 MC 841745 A MC841745 A MC 841745A MC 1745 A MC1745 A MC 1745A MC 1639 A1 MC1639 A1 MC 1639A1
Authority
MC
Monaco
Prior art keywords
group
oxy
formula
carbonyl
propoxy
Prior art date
Application number
MC841745A
Other languages
English (en)
French (fr)
Inventor
Richard Barner
Kaspar Burri
Jean-Marie Cassal
Paul Hadvary
Georges Hirth
Klaus Mueller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1639A1 publication Critical patent/MC1639A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MC841745A 1983-12-30 1984-12-27 Derives de la glycerine MC1639A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH698583 1983-12-30
CH449884 1984-09-20

Publications (1)

Publication Number Publication Date
MC1639A1 true MC1639A1 (fr) 1986-01-09

Family

ID=25695617

Family Applications (1)

Application Number Title Priority Date Filing Date
MC841745A MC1639A1 (fr) 1983-12-30 1984-12-27 Derives de la glycerine

Country Status (15)

Country Link
US (1) US4731373A (da)
EP (1) EP0147768B1 (da)
AU (1) AU571625B2 (da)
CA (1) CA1266476A (da)
DE (1) DE3476661D1 (da)
DK (2) DK160818C (da)
ES (2) ES8603374A1 (da)
FI (1) FI82686C (da)
HU (1) HU195775B (da)
IL (1) IL73920A (da)
MC (1) MC1639A1 (da)
NO (1) NO165192C (da)
NZ (1) NZ210633A (da)
PH (1) PH21482A (da)
PT (1) PT79783B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737518A (en) * 1984-04-03 1988-04-12 Takeda Chemical Industries, Ltd. Lipid derivatives, their production and use
WO1986001507A1 (en) * 1984-08-23 1986-03-13 Sandoz Ag Cyclimmonium salts
US4863941A (en) * 1985-06-18 1989-09-05 Hoffmann-La Roche Inc. Glycerol derivatives
GB8528959D0 (en) * 1985-11-25 1986-01-02 Leo Pharm Prod Ltd Chemical compounds
US5089657A (en) * 1987-03-11 1992-02-18 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
EP0301751B1 (en) * 1987-07-31 1993-03-10 Takeda Chemical Industries, Ltd. Pyridinium derivatives, their production and use
US4920134A (en) * 1987-08-07 1990-04-24 Takeda Chemical Industries, Ltd. 2-O-pyrimidinyl glycerol derivatives
ES2005031A6 (es) * 1987-10-13 1989-02-16 Uriach & Cia Sa J Procedimiento para la obtencion de 1,3-dioxolanos 2,4-disustituidos.
US5185334A (en) * 1989-07-31 1993-02-09 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
WO1989007099A1 (en) * 1988-02-05 1989-08-10 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
WO1989007100A1 (en) * 1988-02-05 1989-08-10 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
EP0336142A3 (en) * 1988-04-04 1991-04-24 American Cyanamid Company Novel antagonists of platelet activating factor
FI97883C (fi) * 1988-07-04 1997-03-10 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen glyserolijohdannaisen valmistamiseksi
US5273985A (en) * 1988-07-04 1993-12-28 Eisai Co., Ltd. Glycerin derivative and its pharmacological use
EP0356765A3 (en) * 1988-08-19 1991-08-07 Takeda Chemical Industries, Ltd. Carboxylic acid derivatives, their production and use
US4981860A (en) * 1989-01-30 1991-01-01 Takeda Chemical Industries, Ltd. Pyridinium nitrate, composition containing same and their use for inhibiting platelet activating factor
ES2013834A6 (es) * 1989-01-30 1990-06-01 Uriach & Cia Sa J Procedimiento para la obtencion de derivados 4-sustituidos de 2-alcoxitetrahidrofurano.
ES2010145A6 (es) * 1989-03-02 1989-10-16 Uriach & Cia Sa J Procedimiento para la obtencion de derivados de la 2-picolilamina.
US5391785A (en) * 1990-01-16 1995-02-21 La Jolla Pharmaceutial Company Intermediates for providing functional groups on the 5' end of oligonucleotides
CA2073846C (en) * 1991-07-15 2007-09-18 David S. Jones Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides
ES2062943B1 (es) * 1993-03-23 1995-11-16 Uriach & Cia Sa J Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas.
KR100361933B1 (ko) * 1993-09-08 2003-02-14 라 졸라 파마슈티칼 컴파니 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
US6458953B1 (en) * 1998-12-09 2002-10-01 La Jolla Pharmaceutical Company Valency platform molecules comprising carbamate linkages
AU2001268228A1 (en) * 2000-06-08 2001-12-17 La Jolla Pharmaceutical Company Multivalent platform molecules comprising high molecular weight polyethylene oxide
RU2414453C2 (ru) * 2008-07-17 2011-03-20 Сергей Иванович МАЛЕКИН 1-алкил-2-алкилкарбамоил-глицерины, обладающие антигипертензивной активностью, и способ их получения
CN107082870A (zh) 2012-03-30 2017-08-22 三菱化学株式会社 环氧组合物
RU2621347C1 (ru) * 2016-05-27 2017-06-02 Государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет "Министерства здравоохранения Российской Федерации (ГБОУ ВПО СибГМУ Минздрава России) Способ получения 1-алкил-2-алкилкарбамоилглицеринов

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE932611C (de) * 1949-12-22 1955-09-05 Ciba Geigy Verfahren zur Herstellung von Polyalkylenglykolaethern isocyclischer Verbindungen
DE1199254B (de) * 1963-09-20 1965-08-26 Krewel Leuffen Gmbh Verfahren zur Herstellung von O, N-Dicarbaethoxyderivaten von substituierten 1, 3-Aminoalkoholen
NL133296C (da) * 1966-12-30
BE741022A (da) * 1968-11-02 1970-04-01
US3686238A (en) * 1970-01-19 1972-08-22 Syntex Corp Glycerol esterified with 2-naphthyl-acetic acids and fatty acids
US3671557A (en) * 1970-09-17 1972-06-20 Smith Kline French Lab 1,2-diacylglycerol 3-(2,2,2-trichloroethyl) carbonates
DE2422170C2 (de) * 1974-05-08 1982-09-23 Bayer Ag, 5090 Leverkusen Polymerisierbare N,N-disubstituierte Carbamoyloxyalkylcarbonsäureester, Verfahren zu ihrer Herstellung und ihre Verwendung
DD121507B1 (de) * 1975-09-29 1989-11-29 Hans Brachwitz Verfahren zur herstellung von 1-o-acyl-und 1-0-alkyl-2-halogenpropandiol-(1,3)
GB1514389A (en) * 1975-12-08 1978-06-14 Abbott Lab Glycerides with antibacterial properties
DE2820892A1 (de) * 1978-05-12 1979-11-22 Nattermann A & Cie Neue strukturanaloga von glyveriden und verfahren zu deren herstellung
US4551532A (en) * 1980-05-08 1985-11-05 Takeda Chemical Industries, Ltd. Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity
EP0054715A3 (de) * 1980-12-18 1982-09-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Propionsäureester, Herstellung dieser Verbindungen, Unkrautbekämpfungsmittel, die diese Verbindungen als Wirkstoffe enthalten, sowie Verwendung solcher Verbindungen und Mittel zur Bekämpfung von Unkräutern
US4493832A (en) * 1981-07-03 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same
JPS58192825A (ja) * 1982-05-06 1983-11-10 Takeda Chem Ind Ltd グリセロール誘導体
EP0094586A3 (en) * 1982-05-13 1984-06-06 Ono Pharmaceutical Co., Ltd. Glycerol derivatives, process for preparing same and pharmaceutical composition containing same
JPS5988447A (ja) * 1982-11-11 1984-05-22 Ono Pharmaceut Co Ltd グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤
JPS60104066A (ja) * 1983-11-10 1985-06-08 Ono Pharmaceut Co Ltd グリセリン誘導体

Also Published As

Publication number Publication date
DK200590D0 (da) 1990-08-21
EP0147768B1 (de) 1989-02-08
PH21482A (en) 1987-10-28
DK160818B (da) 1991-04-22
AU571625B2 (en) 1988-04-21
IL73920A0 (en) 1985-03-31
DK514284D0 (da) 1984-10-26
NO844635L (no) 1985-07-01
US4731373A (en) 1988-03-15
NO165192C (no) 1991-01-09
ES8701138A1 (es) 1986-11-16
PT79783B (en) 1987-01-05
ES547020A0 (es) 1986-11-16
FI82686B (fi) 1990-12-31
IL73920A (en) 1988-06-30
AU3719684A (en) 1985-07-04
FI844332L (fi) 1985-07-01
NZ210633A (en) 1988-08-30
EP0147768A2 (de) 1985-07-10
DK160818C (da) 1991-10-07
ES539136A0 (es) 1986-01-01
FI844332A0 (fi) 1984-11-05
EP0147768A3 (en) 1985-10-09
DK514284A (da) 1985-07-01
HUT37112A (en) 1985-11-28
FI82686C (fi) 1991-04-10
DK200590A (da) 1990-08-21
ES8603374A1 (es) 1986-01-01
NO165192B (no) 1990-10-01
DE3476661D1 (en) 1989-03-16
HU195775B (en) 1988-07-28
PT79783A (en) 1985-01-01
CA1266476A (en) 1990-03-06

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