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MA39951A - Détection de l'adn provenant d'un type spécifique de cellule et méthodes associées - Google Patents

Détection de l'adn provenant d'un type spécifique de cellule et méthodes associées

Info

Publication number
MA39951A
MA39951A MA039951A MA39951A MA39951A MA 39951 A MA39951 A MA 39951A MA 039951 A MA039951 A MA 039951A MA 39951 A MA39951 A MA 39951A MA 39951 A MA39951 A MA 39951A
Authority
MA
Morocco
Prior art keywords
dna
methods
originates
detection
cells
Prior art date
Application number
MA039951A
Other languages
English (en)
Inventor
Sebastian Grömminger
Wera Hofmann
Matthias Sachse
Hamed Said
Original Assignee
Lifecodexx Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP14167775.7A external-priority patent/EP2942401A1/fr
Priority claimed from EP14167769.0A external-priority patent/EP2942400A1/fr
Application filed by Lifecodexx Ag filed Critical Lifecodexx Ag
Publication of MA39951A publication Critical patent/MA39951A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)

Abstract

La présente invention concerne des méthodes permettant de détecter une quantité d'adn qui provient de cellules d'un type donné, l'échantillon comprenant un tel adn mélangé avec de l'adn qui ne provient pas de telles cellules. De telles méthodes sont basées sur une méthylation différentielle, au niveau de certaines régions, de l'adn qui provient du type donné de cellules par comparaison avec l'adn mélangé. De telles méthodes peuvent être appliquées en particulier à la détection, à partir d'un liquide biologique provenant d'une femme enceinte, de l'adn acellulaire provenant d'un fœtus ou du placenta d'un fœtus, ou à la détection, à partir d'un liquide biologique provenant d'un individu, de l'adn acellulaire provenant de cellules d'une tumeur. Par conséquent, de telles méthodes ont une utilité diagnostique, pronostique et/ou prédictive pour détecter un risque accru d'un individu souffrant d'un état de santé tel qu'une prééclampsie ou un cancer ou de développer celui-ci, et/ou pour faciliter des méthodes (ultérieures) diagnostiques, pronostiques et/ou prédictives telles que la détection de la trisomie chromosomique dans un fœtus, y compris des grossesses gémellaires. La présente invention concerne également des compositions, des kits, des produits-programmes informatiques et d'autres aspects qui sont utilisés dans la pratique de telles méthodes, utiles pour celle-ci ou associés à celle-ci.
MA039951A 2014-05-09 2015-05-08 Détection de l'adn provenant d'un type spécifique de cellule et méthodes associées MA39951A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14167775.7A EP2942401A1 (fr) 2014-05-09 2014-05-09 Détection d'ADN qui provient d'un type cellulaire spécifique
EP14167769.0A EP2942400A1 (fr) 2014-05-09 2014-05-09 Détection multiplexe d'ADN qui provient d'un type cellulaire spécifique

Publications (1)

Publication Number Publication Date
MA39951A true MA39951A (fr) 2017-03-15

Family

ID=53189029

Family Applications (1)

Application Number Title Priority Date Filing Date
MA039951A MA39951A (fr) 2014-05-09 2015-05-08 Détection de l'adn provenant d'un type spécifique de cellule et méthodes associées

Country Status (11)

Country Link
US (2) US10801067B2 (fr)
EP (2) EP3521454A1 (fr)
JP (1) JP6681841B2 (fr)
CN (1) CN107223159A (fr)
AU (1) AU2015257654A1 (fr)
CA (1) CA2985134A1 (fr)
IL (1) IL248637A0 (fr)
MA (1) MA39951A (fr)
RU (1) RU2016147914A (fr)
SG (1) SG11201608993RA (fr)
WO (1) WO2015169947A1 (fr)

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US20170314073A1 (en) 2017-11-02
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US20200407793A1 (en) 2020-12-31
US10801067B2 (en) 2020-10-13
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EP3140421B1 (fr) 2020-03-25
EP3140421A1 (fr) 2017-03-15
CA2985134A1 (fr) 2015-11-12
JP6681841B2 (ja) 2020-04-15
EP3521454A1 (fr) 2019-08-07
US11965207B2 (en) 2024-04-23
WO2015169947A9 (fr) 2015-12-30
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