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MA30865B1 - Utilisation de cyclosporines modifiees - Google Patents

Utilisation de cyclosporines modifiees

Info

Publication number
MA30865B1
MA30865B1 MA31842A MA31842A MA30865B1 MA 30865 B1 MA30865 B1 MA 30865B1 MA 31842 A MA31842 A MA 31842A MA 31842 A MA31842 A MA 31842A MA 30865 B1 MA30865 B1 MA 30865B1
Authority
MA
Morocco
Prior art keywords
cyclosporins
modified
modified cyclosporins
cyclophiline
immunosuppressive
Prior art date
Application number
MA31842A
Other languages
English (en)
Inventor
Motoyuki Kohjima
Makoto Nakamuta
Original Assignee
Univ Kyushu
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyushu, Novartis Ag filed Critical Univ Kyushu
Publication of MA30865B1 publication Critical patent/MA30865B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'INVENTION CONCERNE UNE CYCLOSPORINE DE LIAISON À LA CYCLOPHILINE NON IMMUNOSUPPRESSIVE, QUI PRÉSENTE DES PROPRIÉTÉS UTILES DANS LA PRÉVENTION OU LE TRAITEMENT DES MALADIES DU FOIE.
MA31842A 2006-10-12 2009-05-06 Utilisation de cyclosporines modifiees MA30865B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82922806P 2006-10-12 2006-10-12

Publications (1)

Publication Number Publication Date
MA30865B1 true MA30865B1 (fr) 2009-11-02

Family

ID=39092021

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31842A MA30865B1 (fr) 2006-10-12 2009-05-06 Utilisation de cyclosporines modifiees

Country Status (17)

Country Link
US (1) US20100130408A1 (fr)
EP (1) EP2073831A1 (fr)
JP (1) JP5455632B2 (fr)
KR (1) KR20090083902A (fr)
CN (1) CN101557819A (fr)
AU (1) AU2007306316B2 (fr)
BR (1) BRPI0719189A2 (fr)
CA (1) CA2665415A1 (fr)
IL (1) IL197966A0 (fr)
MA (1) MA30865B1 (fr)
MX (1) MX2009003743A (fr)
NO (1) NO20091694L (fr)
RU (1) RU2463071C2 (fr)
SG (1) SG175621A1 (fr)
TN (1) TN2009000135A1 (fr)
WO (1) WO2008043797A1 (fr)
ZA (1) ZA200902300B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011063076A1 (fr) 2009-11-19 2011-05-26 Itherx Pharmaceuticals, Inc. Méthodes de traitement du virus de l'hépatite c avec des composés d'oxo-acétamide
CN101843893B (zh) * 2010-05-21 2012-02-01 中国人民解放军第三军医大学 环孢素a在制备抗轮状病毒药物中的应用
EP2576552A4 (fr) * 2010-06-01 2013-11-13 Aupex Pharmaceutical Inc Inhibiteurs benzoquinolone de vmat2
WO2014047167A1 (fr) 2012-09-18 2014-03-27 Auspex Pharmaceuticals, Inc. Pharmacocinétiques de formulations d'inhibiteurs de benzoquinoline deutéré du transporteur 2 de monoamine vésiculaire
US9550780B2 (en) 2012-09-18 2017-01-24 Auspex Pharmaceuticals, Inc. Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
EA201791466A1 (ru) 2013-12-03 2017-11-30 Оспекс Фармасьютикалз, Инк. Способы получения соединений бензохинолина
KR102528845B1 (ko) 2015-03-06 2023-05-08 오스펙스 파마슈티칼스, 인코포레이티드 비정상적 불수의 운동 장애의 치료 방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
FR2757521B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757522B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
JPH1180026A (ja) * 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
US20030216303A1 (en) * 1998-03-06 2003-11-20 Michael Ambuhl Emulsion preconcentrates containing cyclosporin or a macrolide
USRE40987E1 (en) * 1998-07-01 2009-11-17 Debiopharm S.A. Cyclosporin with improved activity profile
DE60045890D1 (de) * 1999-04-27 2011-06-09 Mitsubishi Tanabe Pharma Corp Arzneimittel zur präventiven oder therapeutische Behandlung von Lebererkrankungen
US7335647B2 (en) * 2000-10-11 2008-02-26 Kensuke Egashira Drugs for liver diseases
US20030213603A1 (en) * 2002-05-14 2003-11-20 Fisher David B. Dual use extension apparatus for a tool
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
US7079552B2 (en) * 2003-09-09 2006-07-18 Harris Corporation Mobile ad hoc network (MANET) with quality-of-service (QoS) protocol hierarchy and related methods
JP4892486B2 (ja) * 2004-10-01 2012-03-07 デビオファーム ソシエテ アノニム Ｃ型肝炎感染の治療のための［ｄ−ｍｅａｌａ］３−［ｅｔｖａｌ］４−シクロスポリンの使用、及び当該［ｄ−ｍｅａｌａ］３−［ｅｔｖａｌ］４−シクロスポリンを含む医薬組成物
SI1802650T1 (sl) * 2004-10-01 2012-03-30 Scynexis Inc Eter in tioeter substituirani ciklosporinski derivati za zdravljenje in preventivo pred infekcijami s hepatitisom c
KR20070087624A (ko) * 2004-12-23 2007-08-28 노파르티스 아게 Ｈｃｖ 치료용 조성물
US8512690B2 (en) * 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors

Also Published As

Publication number Publication date
CA2665415A1 (fr) 2008-04-17
NO20091694L (no) 2009-07-10
SG175621A1 (en) 2011-11-28
RU2009117699A (ru) 2010-11-20
CN101557819A (zh) 2009-10-14
JP2010505912A (ja) 2010-02-25
KR20090083902A (ko) 2009-08-04
MX2009003743A (es) 2009-06-18
JP5455632B2 (ja) 2014-03-26
AU2007306316A1 (en) 2008-04-17
AU2007306316B2 (en) 2011-10-27
TN2009000135A1 (en) 2010-10-18
ZA200902300B (en) 2010-10-27
BRPI0719189A2 (pt) 2018-08-14
WO2008043797A1 (fr) 2008-04-17
RU2463071C2 (ru) 2012-10-10
EP2073831A1 (fr) 2009-07-01
US20100130408A1 (en) 2010-05-27
IL197966A0 (en) 2011-08-01

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