| Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2 D Héja, A Kocsis, J Dobó, K Szilágyi, R Szász, P Závodszky, G Pál, P Gál Proceedings of the National Academy of Sciences 109 (26), 10498-10503, 2012 | 300 | 2012 |
| MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity J Dobó, V Harmat, L Beinrohr, E Sebestyén, P Závodszky, P Gál The Journal of Immunology 183 (2), 1207-1214, 2009 | 174 | 2009 |
| Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of α1-proteinase inhibitor with porcine pancreatic elastase A Dementiev, J Dobó, PGW Gettins Journal of Biological Chemistry 281 (6), 3452-3457, 2006 | 168 | 2006 |
| MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked J Dobó, D Szakács, G Oroszlán, E Kortvely, B Kiss, E Boros, R Szász, ... Scientific reports 6 (1), 31877, 2016 | 163 | 2016 |
| Effects of MASP-1 of the complement system on activation of coagulation factors and plasma clot formation K Hess, R Ajjan, F Phoenix, J Dobó, P Gál, V Schroeder PloS one 7 (4), e35690, 2012 | 155 | 2012 |
| C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease L Beinrohr, V Harmat, J Dobó, Z Loörincz, P Gál, P Závodszky Journal of Biological Chemistry 282 (29), 21100-21109, 2007 | 143 | 2007 |
| Structural basis for activation of the complement system by component C4 cleavage RT Kidmose, NS Laursen, J Dobó, TR Kjaer, S Sirotkina, L Yatime, ... Proceedings of the National Academy of Sciences 109 (38), 15425-15430, 2012 | 141 | 2012 |
| Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions P Gál, J Dobó, P Závodszky, RBM Sim Molecular immunology 46 (14), 2745-2752, 2009 | 139 | 2009 |
| Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1 J Dobó, B Major, KA Kékesi, I Szabó, M Megyeri, K Hajela, G Juhász, ... PloS one 6 (5), e20036, 2011 | 136 | 2011 |
| C1, MBL–MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation L Beinrohr, J Dobó, P Závodszky, P Gál Trends in Molecular Medicine 14 (12), 511-521, 2008 | 133 | 2008 |
| Multiple roles of complement MASP-1 at the interface of innate immune response and coagulation J Dobó, V Schroeder, L Jenny, L Cervenak, P Závodszky, P Gál Molecular immunology 61 (2), 69-78, 2014 | 125 | 2014 |
| Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system SE Degn, L Jensen, P Gál, J Dobó, SH Holmvad, JC Jensenius, S Thiel Journal of immunological methods 361 (1-2), 37-50, 2010 | 120 | 2010 |
| Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and-2 are essential for lectin pathway activation and reveal structural … D Héja, V Harmat, K Fodor, M Wilmanns, J Dobó, KA Kékesi, P Závodszky, ... Journal of Biological Chemistry 287 (24), 20290-20300, 2012 | 116 | 2012 |
| The emerging roles of mannose‐binding lectin‐associated serine proteases (MASP s) in the lectin pathway of complement and beyond J Dobó, G Pál, L Cervenak, P Gál Immunological reviews 274 (1), 98-111, 2016 | 115 | 2016 |
| The control of the complement lectin pathway activation revisited: both C1-inhibitor and antithrombin are likely physiological inhibitors, while α2-macroglobulin is not K Paréj, J Dobó, P Závodszky, P Gál Molecular immunology 54 (3-4), 415-422, 2013 | 112 | 2013 |
| Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in … S Thiel, L Jensen, SE Degn, HJ Nielsen, P Gál, J Dobó, JC Jensenius Clinical & Experimental Immunology 169 (1), 38-48, 2012 | 109 | 2012 |
| Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors NKH Wong, M Kojima, J Dobo, G Ambrus, RB Sim Molecular immunology 36 (13-14), 853-861, 1999 | 103 | 1999 |
| Be on target: strategies of targeting alternative and lectin pathway components in complement-mediated diseases J Dobó, A Kocsis, P Gál Frontiers in immunology 9, 1851, 2018 | 98 | 2018 |
| Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation … M Megyeri, V Harmat, B Major, Á Végh, J Balczer, D Héja, K Szilágyi, ... Journal of Biological Chemistry 288 (13), 8922-8934, 2013 | 98 | 2013 |
| Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and-2 … A Kocsis, KA Kékesi, R Szász, BM Végh, J Balczer, J Dobó, P Závodszky, ... The Journal of Immunology 185 (7), 4169-4178, 2010 | 97 | 2010 |
Péter GálInstitute of Molecular Life Sciences, HUN-REN, Research Centre for Natural SciencesVerified email at enzim.hu
