| The serpins are an expanding superfamily of structurally similar but functionally diverse proteins GA Silverman, PI Bird, RW Carrell, FC Church, PB Coughlin, PGW Gettins, ... Journal of Biological Chemistry 276 (36), 33293-33296, 2001 | 1644 | 2001 |
| Serpin structure, mechanism, and function PGW Gettins Chemical reviews 102 (12), 4751-4804, 2002 | 1622 | 2002 |
| Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 Å and full insertion of the reactive center loop into β-sheet A E Stratikos, PGW Gettins Proceedings of the National Academy of Sciences 96 (9), 4808-4813, 1999 | 281 | 1999 |
| Mechanism of serpin action: evidence that C1 inhibitor functions as a suicide substrate PA Patston, P Gettins, J Beechem, M Schapira Biochemistry 30 (36), 8876-8882, 1991 | 233 | 1991 |
| Molecular mechanisms of antithrombin–heparin regulation of blood clotting proteinases. A paradigm for understanding proteinase regulation by serpin family protein proteinase … ST Olson, B Richard, G Izaguirre, S Schedin-Weiss, PGW Gettins Biochimie 92 (11), 1587-1596, 2010 | 232 | 2010 |
| Alkaline phosphatase, solution structure, and mechanism JE Coleman, P Gettins Advances in Enzymology and Related Areas of Molecular Biology 55, 381-452, 1983 | 222 | 1983 |
| Serpins: structure, function and biology PGW Gettins, PA Patston, ST Olson Chapman & Hall, 1996 | 196 | 1996 |
| Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor M Simonovic, PGW Gettins, K Volz Proceedings of the National Academy of Sciences 98 (20), 11131-11135, 2001 | 191 | 2001 |
| The ternary complex of antithrombin–anhydrothrombin–heparin reveals the basis of inhibitor specificity A Dementiev, M Petitou, JM Herbert, PGW Gettins Nature structural & molecular biology 11 (9), 863-867, 2004 | 183 | 2004 |
| Major proteinase movement upon stable serpin–proteinase complex formation E Stratikos, PGW Gettins Proceedings of the National Academy of Sciences 94 (2), 453-458, 1997 | 174 | 1997 |
| Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of α1-proteinase inhibitor with porcine pancreatic elastase A Dementiev, J Dobó, PGW Gettins Journal of Biological Chemistry 281 (6), 3452-3457, 2006 | 168 | 2006 |
| Pathogenic α1-antitrypsin polymers are formed by reactive loop-β-sheet A linkage P Sivasothy, TR Dafforn, PGW Gettins, DA Lomas Journal of Biological Chemistry 275 (43), 33663-33668, 2000 | 166 | 2000 |
| Mechanism of heparin activation of antithrombin. Evidence for reactive center loop preinsertion with expulsion upon heparin binding JA Huntington, ST Olson, B Fan, PGW Gettins Biochemistry 35 (26), 8495-8503, 1996 | 157 | 1996 |
| The role of conformational change in serpin structure and function P Gettins, PA Patston, M Schapira Bioessays 15 (7), 461-467, 1993 | 144 | 1993 |
| . alpha. 1-Proteinase Inhibitor Variant T345R. Influence of P14 Residue on Substrate and Inhibitory Pathways DB Hood, JA Huntington, PGW Gettins Biochemistry 33 (28), 8538-8547, 1994 | 139 | 1994 |
| Exosite determinants of serpin specificity PGW Gettins, ST Olson Journal of Biological Chemistry 284 (31), 20441-20445, 2009 | 116 | 2009 |
| Mechanism of acceleration of antithrombin-proteinase reactions by low affinity heparin: role of the antithrombin binding pentasaccharide in heparin rate enhancement VJ Streusand, I Björk, PGW Gettins, M Petitou, ST Olson Journal of Biological Chemistry 270 (16), 9043-9051, 1995 | 113 | 1995 |
| Inhibitory serpins. New insights into their folding, polymerization, regulation and clearance PGW Gettins, ST Olson Biochemical Journal 473 (15), 2273-2293, 2016 | 108 | 2016 |
| Transmission of conformational change from the heparin binding site to the reactive center of antithrombin PGW Gettins, B Fan, BC Crews, IV Turko, ST Olson, VJ Streusand Biochemistry 32 (33), 8385-8389, 1993 | 108 | 1993 |
| NMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related protein W Huang, K Dolmer, PGW Gettins Journal of Biological Chemistry 274 (20), 14130-14136, 1999 | 105 | 1999 |
Klavs DolmerField Service Engineer, Agilent TechnologiesVerified email at agilent.com
