| SMARTCyp: a 2D method for prediction of cytochrome P450-mediated drug metabolism P Rydberg, DE Gloriam, J Zaretzki, C Breneman, L Olsen ACS medicinal chemistry letters 1 (3), 96-100, 2010 | 366 | 2010 |
| Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities M Groenning, L Olsen, M van de Weert, JM Flink, S Frokjaer, ... Journal of structural biology 158 (3), 358-369, 2007 | 336 | 2007 |
| Ionotropic glutamate-like receptor δ2 binds D-serine and glycine P Naur, KB Hansen, AS Kristensen, SM Dravid, DS Pickering, L Olsen, ... Proceedings of the National Academy of Sciences 104 (35), 14116-14121, 2007 | 195 | 2007 |
| 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ... Chemical science 4 (8), 3110-3117, 2013 | 194 | 2013 |
| The SMARTCyp cytochrome P450 metabolism prediction server P Rydberg, DE Gloriam, L Olsen Bioinformatics 26 (23), 2988-2989, 2010 | 173 | 2010 |
| Prediction of activation energies for hydrogen abstraction by cytochrome P450 L Olsen, P Rydberg, TH Rod, U Ryde Journal of medicinal chemistry 49 (22), 6489-6499, 2006 | 143 | 2006 |
| Location of the antidepressant binding site in the serotonin transporter J Andersen, O Taboureau, KB Hansen, L Olsen, J Egebjerg, ... Journal of Biological Chemistry 284 (15), 10276-10284, 2009 | 140 | 2009 |
| Thioflavin T hydroxylation at basic pH and its effect on amyloid fibril detection V Fodera, M Groenning, V Vetri, F Librizzi, S Spagnolo, C Cornett, L Olsen, ... The Journal of Physical Chemistry B 112 (47), 15174-15181, 2008 | 140 | 2008 |
| Quantum chemical geometry optimizations in proteins using crystallographic raw data U Ryde, L Olsen, K Nilsson Journal of computational chemistry 23 (11), 1058-1070, 2002 | 132 | 2002 |
| Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques P Vasanthanathan, O Taboureau, C Oostenbrink, NPE Vermeulen, ... Drug Metabolism and Disposition 37 (3), 658-664, 2009 | 127 | 2009 |
| Prediction of cytochrome P450 mediated metabolism L Olsen, C Oostenbrink, FS Jørgensen Advanced drug delivery reviews 86, 61-71, 2015 | 125 | 2015 |
| Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter J Andersen, L Olsen, KB Hansen, O Taboureau, FS Jørgensen, ... Journal of Biological Chemistry 285 (3), 2051-2063, 2010 | 122 | 2010 |
| SMARTCyp 3.0: enhanced cytochrome P450 site-of-metabolism prediction server L Olsen, M Montefiori, KP Tran, FS Jørgensen Bioinformatics 35 (17), 3174-3175, 2019 | 108 | 2019 |
| Sulfoxide, sulfur, and nitrogen oxidation and dealkylation by cytochrome P450 P Rydberg, U Ryde, L Olsen Journal of chemical theory and computation 4 (8), 1369-1377, 2008 | 106 | 2008 |
| RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes J Zaretzki, P Rydberg, C Bergeron, KP Bennett, L Olsen, CM Breneman Journal of chemical information and modeling 52 (6), 1637-1659, 2012 | 100 | 2012 |
| Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4‐pyridine‐dicarboxylic acid as an in vitro and … LH Kristensen, AL Nielsen, C Helgstrand, M Lees, P Cloos, JS Kastrup, ... The FEBS journal 279 (11), 1905-1914, 2012 | 96 | 2012 |
| Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands P Vasanthanathan, J Hritz, O Taboureau, L Olsen, F Steen Jørgensen, ... Journal of chemical information and modeling 49 (1), 43-52, 2009 | 92 | 2009 |
| Evaluation of carbohydrate molecular mechanical force fields by quantum mechanical calculations L Hemmingsen, DE Madsen, AL Esbensen, L Olsen, SB Engelsen Carbohydrate research 339 (5), 937-948, 2004 | 82 | 2004 |
| New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design L Olsen, S Jost, HW Adolph, I Pettersson, L Hemmingsen, FS Jørgensen Bioorganic & medicinal chemistry 14 (8), 2627-2635, 2006 | 73 | 2006 |
| Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction A Bach, CN Chi, GF Pang, L Olsen, AS Kristensen, P Jemth, ... Angewandte Chemie International Edition 48 (51), 9685-9689, 2009 | 72 | 2009 |
Flemming Steen JørgensenProfessor, Department of Drug Design and Pharmacology, University of CopenhagenVerified email at sund.ku.dk
